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MLGN 201 Fall 2019-2020: X Inactivation

13 Questions

2 Views

3.4 Stars

MLGN 201 Fall 2019-2020: X Inactivation

Created by

@TenderRing

Questions and Answers

What is the length of the human X chromosome in mega bases (MB)?

155 MB

How many protein coding genes are there on the X chromosome?

826

What does the rest of the X chromosome consist of, apart from the genes?

Interspersed DNA sequences

What is the gene density of the X chromosome compared to other chromosomes of similar size?

<p>Somewhat less gene-dense</p> Signup and view all the answers

In what context do the interspersed DNA sequences occur?

<p>Repeats all over our genome</p> Signup and view all the answers

What is the intended learning outcome of the lecture on X inactivation mechanisms and impacts?

<p>Describe the concept of gene regulation in eukaryotes</p> Signup and view all the answers

What is the ultimate goal of X inactivation?

<p>To equalize the expression of genes between members of different biological sexes</p> Signup and view all the answers

What is the Barr body?

<p>The inactivated X chromosome in female mammals</p> Signup and view all the answers

Which statement about X inactivation is not true?

<p>In extra embryonic membranes, only the paternal X is activated</p> Signup and view all the answers

At what stage does the onset of X inactivation vary with respect to?

<p>Blastocyst and embryonic stage</p> Signup and view all the answers

.What is the function of Xist RNA during X inactivation?

<p>Spreads to coat the inactive X chromosome and does not interact directly with DNA</p> Signup and view all the answers

.What is the function of Xce in relation to the X chromosome?

<p>Controls the activity of Xist RNA</p> Signup and view all the answers

.What is the purpose of Xic (X chromosome-inactivation center)?

<p>To initiate X inactivation on one of the X chromosomes</p> Signup and view all the answers

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