11 Questions
Which environmental factors can affect mitochondrial function?
Chemicals, drugs, and antibiotics
Which type of inhibitors are used for HIV/HBV treatment to inhibit DNA POL?
DNA polymerase inhibitors
What can some antibiotics cause for specific mtDNA variants?
Organ of Corti hair cell loss and deafness
What do variants in the 12s rRNA gene make rRNA more like?
Bacterial rRNA
What is directly involved in β-cell signaling associated with obesity and adult-onset diabetes?
Mitochondria
What selectively metabolizes glucose into G-6-P then shunts glycolysis products to mitochondria to increase ATP?
Mitochondria
What inactivates/closes K+ channel allowing depolarization of the membrane?
ATP
What stimulates the release of insulin from vesicles in β-cells?
Calcium
What induces changes in methylation of the promoter region for PGC-1α?
Diet
What is potentially linked to neurological disorders with aging?
Gradual mitochondrial decline
What should be employed when considering specific antibiotic treatments?
Pharmacogenomics
Test your knowledge of multifactorial diseases associated with mitochondria with this quiz. Learn about how environmental chemicals, drugs, and antibiotics can impact mitochondrial function and cause conditions such as deafness and organ damage. Explore the effects of DNA polymerase inhibitors and mitochondrial toxins in the context of HIV and HBV treatment.
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