Microbiology and Antibiotics Mechanisms Lecture Notes
5 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Peptidoglycan synthesis begins with the stepwise synthesis in the cytoplasm of UDP-N-acetylmuramic acid-______

pentapeptide

The synthesis of UDP-N-acetylmuramic acid-pentapeptide involves the condensation of N-Acetylglucosamine with uridine diphosphate and then conversion to UDP-N-acetylmuramic acid by condensation with phosphoenolpyruvate and reduction in a series of ______

reactions

The amino acids of the pentapeptide are sequentially added without the involvement of ribosomes and tRNA, instead, each addition is catalyzed by a different enzyme and involves the split of ______ to ADP + Pi

ATP

The final cross-linking of peptidoglycan is accomplished by a transpeptidation reaction in which the free amino group of a pentaglycine residue displaces the terminal D-alanine residue of a neighboring pentapeptide, catalyzed by one of a set of enzymes called ______

<p>penicillin-binding proteins (PBPs)</p> Signup and view all the answers

D-Cycloserine interferes with one of the early stages of synthesis of peptidoglycan involving the assembly of the dipeptide D-alanyl-D-alanine by inhibiting the racemase enzyme which converts L-alanine to D-alanine and a ______ which couples two D-alanines together

<p>ligase</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser