Mechanisms of Health and Disease II: Neuromuscular Unit Quiz
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Questions and Answers

What is the driving force for Na+ influx at resting membrane potentials?

  • Greater concentration of Na+ outside the cell than inside (correct)
  • Inactivation of the Na+ channels
  • Greater concentration of Na+ inside the cell than outside
  • Desensitization of the nicotinic acetylcholine receptor

What triggers the firing of an action potential by the muscle cell?

  • Desensitization of the nicotinic acetylcholine receptor
  • Depolarization of the muscle membrane (correct)
  • Inactivation of the voltage-gated sodium channels
  • Repolarization of the muscle membrane

How many acetylcholine molecules bind to the nicotinic acetylcholine receptor to activate it?

  • 2 (correct)
  • 1
  • 3
  • 4

What is the primary location of acetylcholinesterase (AChE) in the neuromuscular junction?

<p>In the clefts of the neuromuscular junction (D)</p> Signup and view all the answers

What is the central problem of the neuromuscular junction?

<p>Translating neuronal signals to muscular signals at a sustainable rate (D)</p> Signup and view all the answers

What is the key concept about the neuromuscular junction?

<p>It is characterized by extensive folding of the membrane at the postsynaptic site (A)</p> Signup and view all the answers

What are the objectives related to the neuromuscular junction?

<p>Explaining how drugs and toxins can affect the neuromuscular junction (D)</p> Signup and view all the answers

What is the main characteristic of the neuromuscular junction?

<p>Sustainable translation of motor neuron signals to muscle cell signals (B)</p> Signup and view all the answers

What is the role of the presynaptic membrane?

<p>To release ACh into the synaptic cleft (A)</p> Signup and view all the answers

What is the function of rapsyn at the neuromuscular junction?

<p>To cluster nicotinic acetylcholine receptors (B)</p> Signup and view all the answers

How does the amount of ACh in a synaptic vesicle impact the postsynaptic membrane?

<p>It causes a 0.3 to 0.5 mV depolarization (A)</p> Signup and view all the answers

What happens when voltage-gated Ca+2 channels on the presynaptic membrane allow Ca+2 to enter the cytoplasm?

<p>Vesicles dock and become competent to release neurotransmitter (A)</p> Signup and view all the answers

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