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Mechanisms of Health and Disease II: Neuromuscular Unit Quiz

12 Questions

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Mechanisms of Health and Disease II: Neuromuscular Unit Quiz

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Questions and Answers

What is the driving force for Na+ influx at resting membrane potentials?

Greater concentration of Na+ outside the cell than inside (correct)

Inactivation of the Na+ channels

Greater concentration of Na+ inside the cell than outside

Desensitization of the nicotinic acetylcholine receptor

What triggers the firing of an action potential by the muscle cell?

Desensitization of the nicotinic acetylcholine receptor

Depolarization of the muscle membrane (correct)

Inactivation of the voltage-gated sodium channels

Repolarization of the muscle membrane

How many acetylcholine molecules bind to the nicotinic acetylcholine receptor to activate it?

2 (correct)

What is the primary location of acetylcholinesterase (AChE) in the neuromuscular junction?

In the clefts of the neuromuscular junction Signup and view all the answers

What is the central problem of the neuromuscular junction?

Translating neuronal signals to muscular signals at a sustainable rate Signup and view all the answers

What is the key concept about the neuromuscular junction?

It is characterized by extensive folding of the membrane at the postsynaptic site Signup and view all the answers

What are the objectives related to the neuromuscular junction?

Explaining how drugs and toxins can affect the neuromuscular junction Signup and view all the answers

What is the main characteristic of the neuromuscular junction?

Sustainable translation of motor neuron signals to muscle cell signals Signup and view all the answers

What is the role of the presynaptic membrane?

To release ACh into the synaptic cleft Signup and view all the answers

What is the function of rapsyn at the neuromuscular junction?

To cluster nicotinic acetylcholine receptors Signup and view all the answers

How does the amount of ACh in a synaptic vesicle impact the postsynaptic membrane?

It causes a 0.3 to 0.5 mV depolarization Signup and view all the answers

What happens when voltage-gated Ca+2 channels on the presynaptic membrane allow Ca+2 to enter the cytoplasm?

Vesicles dock and become competent to release neurotransmitter Signup and view all the answers