A&P The 7 Steps @ Neuromuscular Junction
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Questions and Answers

What happens after an action potential travels down the axon?

  • It triggers muscle contractions
  • It causes calcium to enter the cell
  • It releases acetylcholine
  • It reaches the axon terminal (correct)

What enters the axon terminal when electrically gated calcium channels open?

Calcium

What does calcium cause the vesicles to release?

ACH

ACH binds to receptors on the muscle after diffusing across the synaptic cleft.

<p>True (A)</p> Signup and view all the answers

What happens when ACH binding opens ion channels?

<p>Sodium rushes into the muscles (C)</p> Signup and view all the answers

What occurs if the muscle reaches the threshold of -55mV at the motor end plate?

<p>An action potential occurs on the muscle</p> Signup and view all the answers

Who breaks down ACH?

<p>Acetylcholine esterase</p> Signup and view all the answers

Study Notes

Neuromuscular Junction: Steps of Action Potential Transmission

  • An action potential (AP) travels down the axon to the axon terminal, initiating neurotransmitter release.
  • Voltage-gated calcium channels open in response to the AP, allowing calcium ions to enter the axon terminal.
  • The influx of calcium ions triggers vesicles to release acetylcholine (ACh) into the synaptic cleft.
  • Acetylcholine diffuses across the synaptic cleft and binds to its receptors on the muscle fibers.
  • Binding of ACh to receptors opens ion channels, resulting in sodium ions rushing into the muscle cells.
  • If the muscle reaches the threshold of -55mV at the motor end plate, it generates an action potential in the muscle.
  • Acetylcholine is broken down by acetylcholine esterase, terminating the signal and preventing continuous stimulation.

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Description

This quiz covers the essential steps involved in neuromuscular transmission, detailing the role of action potentials and calcium in synaptic function. It focuses on the release and action of acetylcholine at the neuromuscular junction. Perfect for anatomy and physiology students wanting to reinforce their understanding.

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