Manuka Honey Benefits and Potency
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Manuka Honey Benefits and Potency

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Questions and Answers

What does a higher UMF number indicate in Manuka honey?

  • Higher concentration of sugars.
  • Increased flavor intensity.
  • Higher moisture content.
  • Stronger antibacterial activity. (correct)
  • Which of the following best describes MGO in Manuka honey?

  • A measurement of sugar levels.
  • A direct measurement of methylglyoxal concentration. (correct)
  • A grading system for taste.
  • A scale for anti-inflammatory properties.
  • Why might UMF provide a more accurate representation of Manuka honey's antibacterial activity compared to MGO?

  • UMF is based on general honey production techniques.
  • MGO focuses solely on flavor profiles.
  • MGO only measures microbial resistance.
  • UMF accounts for other antibacterial factors besides methylglyoxal. (correct)
  • What are the recommended daily usage amounts of Manuka honey?

    <p>1-2 tablespoons.</p> Signup and view all the answers

    Which of the following applications is NOT a common use for Manuka honey?

    <p>As a hair conditioner.</p> Signup and view all the answers

    What role does melatonin play in the sleep-wake cycle?

    <p>It regulates the sleep-wake cycle based on ambient light.</p> Signup and view all the answers

    Which of the following is a common side effect of melatonin supplementation?

    <p>Daytime sleepiness</p> Signup and view all the answers

    In which situation is ramelteon primarily prescribed?

    <p>For chronic insomnia</p> Signup and view all the answers

    How does valerian root assist with sleep?

    <p>By increasing GABA activity in the brain</p> Signup and view all the answers

    What is a potential interaction between melatonin and other medications?

    <p>Melatonin may increase the risk of bleeding with blood thinners.</p> Signup and view all the answers

    What is the primary use of Jamieson Relaxing Herbal Formula?

    <p>To relieve insomnia and reduce nervous tension</p> Signup and view all the answers

    Which ingredient in the formula is primarily recognized for its use as a sedative to relieve anxiety?

    <p>Valerian Extract</p> Signup and view all the answers

    What benefit does Catnip Extract provide in the Jamieson Relaxing Herbal Formula cap?

    <p>Treats stomach cramps and irritations</p> Signup and view all the answers

    What is a combined effect of the Jamieson Relaxing Herbal Formula when used together?

    <p>Relieves gastrointestinal problems related to anxiety</p> Signup and view all the answers

    Which extract in the formula is considered best for mild to moderate anxiety?

    <p>Passion Flower Extract</p> Signup and view all the answers

    What primary benefit is Maca commonly associated with?

    <p>Enhancing cognitive function</p> Signup and view all the answers

    Which condition is saffron NOT indicated to help with?

    <p>High blood pressure</p> Signup and view all the answers

    Which vitamin is found in high levels in royal jelly?

    <p>Vitamin B6</p> Signup and view all the answers

    What is one of the key functions of saffron as a supplement?

    <p>Increasing serotonin levels</p> Signup and view all the answers

    Which group of individuals should exercise caution when using royal jelly?

    <p>Asthmatic patients</p> Signup and view all the answers

    What is a primary benefit of taking Maca supplements?

    <p>Support hormone balance</p> Signup and view all the answers

    Which of the following is an indication for using FluShield?

    <p>Boosting immunity against colds</p> Signup and view all the answers

    How is Maca believed to affect energy levels?

    <p>By boosting energy and stamina</p> Signup and view all the answers

    What is the recommended frequency of taking FluShield for adults?

    <p>Three times daily</p> Signup and view all the answers

    Which of the following describes a role of Maca in relation to cognitive function?

    <p>It may improve mood and enhance cognitive function</p> Signup and view all the answers

    What is one potential consequence of being underweight?

    <p>Inhibited growth</p> Signup and view all the answers

    Which dietary strategy is recommended for gaining weight?

    <p>Eat more frequently</p> Signup and view all the answers

    Which of the following supplements is used to improve nutrition in older, undernourished people?

    <p>Branched-chain amino acids</p> Signup and view all the answers

    What is the purpose of Biored Forte® Capsules?

    <p>Stimulating appetite and improving digestion</p> Signup and view all the answers

    Which pharmacological intervention is recommended for individuals with a BMI of 27 or higher who have comorbidities?

    <p>Medication</p> Signup and view all the answers

    What is a recommended dose of branched-chain amino acids for improving nutrition in older, undernourished individuals?

    <p>4 grams taken three times daily</p> Signup and view all the answers

    What is one of the indications for using Biored Forte® Capsules?

    <p>Low body weight</p> Signup and view all the answers

    Which of the following is NOT a tip for gaining weight?

    <p>Exercise 60 minutes a day</p> Signup and view all the answers

    Which supplement has been suggested to improve depression symptoms in people with anorexia?

    <p>Zinc gluconate</p> Signup and view all the answers

    What is the aim of dietary modifications for obesity management?

    <p>Aim for a 600 kcal daily energy deficit</p> Signup and view all the answers

    What is one of the roles of chromium in managing obesity?

    <p>Helps maintain healthy blood sugar levels</p> Signup and view all the answers

    Which dietary supplement is recommended to help relieve PMS symptoms?

    <p>Vitamin B6</p> Signup and view all the answers

    What is the primary benefit of taking evening primrose oil?

    <p>Relieves symptoms of PMS</p> Signup and view all the answers

    What dietary supplement is specifically indicated to help with dysmenorrhea?

    <p>Fish oil omega-3s</p> Signup and view all the answers

    Which vitamin is essential for preventing neural tube defects (NTDs) during pregnancy?

    <p>Folic Acid</p> Signup and view all the answers

    What is one of the primary roles of chromium in managing obesity?

    <p>Increasing insulin sensitivity</p> Signup and view all the answers

    Which dietary supplement is primarily recommended for preventing neural tube defects during pregnancy?

    <p>Folic Acid</p> Signup and view all the answers

    What is a significant benefit of taking evening primrose oil?

    <p>Reducing symptoms of PMS</p> Signup and view all the answers

    Which supplement is indicated for providing relief from painful menstrual cramps due to dysmenorrhea?

    <p>Omega-3 fish oil</p> Signup and view all the answers

    What is an effect of adequate calcium and vitamin D intake during pregnancy?

    <p>Supporting bone health</p> Signup and view all the answers

    What is a primary indication of Biored Forte® Capsules?

    <p>Low body weight</p> Signup and view all the answers

    Which of the following is a recommended dose of zinc for improving nutrition in individuals with anorexia?

    <p>100 mg of zinc gluconate daily</p> Signup and view all the answers

    What is one of the aims of dietary modifications for obesity management?

    <p>Create a daily energy deficit of 600 kcal</p> Signup and view all the answers

    Which dietary strategy is advised for gaining weight effectively?

    <p>Eat more frequently and choose nutrient-rich foods</p> Signup and view all the answers

    Which of the following medications is included in pharmacological interventions for individuals with a BMI ≥30?

    <p>Saxenda or Victoza</p> Signup and view all the answers

    What is a common effect of being underweight?

    <p>Inhibited growth</p> Signup and view all the answers

    Which of the following is a dietary strategy to effectively gain weight?

    <p>Consume more calorie-dense foods</p> Signup and view all the answers

    What is the recommended dosage for branched-chain amino acids in older, undernourished individuals?

    <p>4 grams taken three times daily</p> Signup and view all the answers

    Which dietary supplement is suggested to stimulate appetite in underweight individuals?

    <p>Dried Brewer Yeast</p> Signup and view all the answers

    What is the primary aim of pharmacological interventions for individuals with a BMI ≥30?

    <p>Mimic GLP-1 to regulate appetite</p> Signup and view all the answers

    Which supplement is recommended for improving insulin sensitivity and managing obesity?

    <p>Jamieson Chelated Chromium</p> Signup and view all the answers

    What is one of the significant roles of folic acid during pregnancy?

    <p>Preventing neural tube defects</p> Signup and view all the answers

    Which of the following is a key benefit of evening primrose oil?

    <p>Reduction of PMS symptoms</p> Signup and view all the answers

    What supplementation is suggested to combat painful menstrual cramps due to dysmenorrhea?

    <p>Omega-3 Fatty Acids</p> Signup and view all the answers

    Which statement correctly describes the symptoms required for a PMDD diagnosis?

    <p>Symptoms must be present in at least three consecutive menstrual cycles.</p> Signup and view all the answers

    Which dietary supplement is thought to be effective in reducing hot flushes during menopause?

    <p>St. John's wart</p> Signup and view all the answers

    What is the main dietary benefit of zinc supplementation in relation to hair health?

    <p>Strengthens the protein structure of hair follicles</p> Signup and view all the answers

    Which of the following supplements is indicated for treating age-related osteoporosis when combined with fish oil?

    <p>Calcium</p> Signup and view all the answers

    What is the recommended dosage frequency for Cystine B6® tablets to promote hair health?

    <p>2 tablets twice daily</p> Signup and view all the answers

    Which of the following supplements has shown evidence to likely reduce triglyceride levels effectively?

    <p>Green Tea</p> Signup and view all the answers

    What is a primary benefit of using chromium supplements?

    <p>Improves insulin sensitivity and helps manage obesity</p> Signup and view all the answers

    Which dietary supplement is specifically indicated for the prevention of neural tube defects during pregnancy?

    <p>Folic Acid</p> Signup and view all the answers

    What common symptom of menopause is characterized by sudden sensations of heat and sweating?

    <p>Hot flashes</p> Signup and view all the answers

    What is a primary benefit of consuming branched-chain amino acids for undernourished individuals?

    <p>Reduce anorexia and improve overall nutrition.</p> Signup and view all the answers

    Which dietary supplement is recommended to relieve symptoms of PMS?

    <p>Evening Primrose Oil</p> Signup and view all the answers

    Which human physiological issue is most directly associated with being underweight?

    <p>Fertility issues.</p> Signup and view all the answers

    Which of the following dietary supplements may help manage painful menstrual cramps associated with dysmenorrhea?

    <p>Vitamin B1 (Thiamine)</p> Signup and view all the answers

    What is the recommended dose of zinc gluconate to potentially aid in weight gain for individuals with anorexia?

    <p>100 mg daily.</p> Signup and view all the answers

    Which dietary modification is specifically recommended for obesity management?

    <p>Reduce daily energy intake by 600 kcal.</p> Signup and view all the answers

    Which ingredient in Biored Forte® Capsules is known to improve digestion?

    <p>Dried Brewer Yeast.</p> Signup and view all the answers

    What is a primary benefit of Vitamin E supplementation?

    <p>Provides antioxidant effects</p> Signup and view all the answers

    Which condition is Vitamin D indicated for when dosed appropriately?

    <p>Hypocalcemia</p> Signup and view all the answers

    What should be avoided when taking L-Arginine due to potential interactions?

    <p>PDE 5 inhibitors</p> Signup and view all the answers

    Which dietary supplement is often used to manage symptoms of BPH?

    <p>Saw Palmetto</p> Signup and view all the answers

    For which condition is the combination of Vitamin E and Vitamin C suggested?

    <p>Dementia</p> Signup and view all the answers

    What is the recommended daily dosage range of zinc for addressing infertility issues?

    <p>66-500 mg</p> Signup and view all the answers

    Which mineral is primarily indicated for improving muscle contractility and helping lower blood pressure?

    <p>Magnesium</p> Signup and view all the answers

    What is the most commonly used formulation for treating iron-deficiency anemia?

    <p>Ferrous sulfate</p> Signup and view all the answers

    How much vitamin C can enhance iron absorption when consumed with iron supplements?

    <p>200 mg per 30 mg iron</p> Signup and view all the answers

    What concentration of elemental zinc is provided by Jamieson Zinc 10 mg?

    <p>77.6 mg of Zinc Gluconate</p> Signup and view all the answers

    Which dietary supplement is considered effective for reducing hot flushes during menopause?

    <p>Soy isoflavones</p> Signup and view all the answers

    Which of the following treatments is specifically indicated for managing vaginal dryness in menopausal women?

    <p>Local vaginal estrogen</p> Signup and view all the answers

    Which combination of supplements is recommended for treating age-related osteoporosis?

    <p>Evening primrose, fish oil, and calcium</p> Signup and view all the answers

    What is the primary function of Cysteine in Cystine B6® tablets concerning hair health?

    <p>Transporting essential minerals for hair regrowth</p> Signup and view all the answers

    Which dietary supplement is likely effective in the management of hypercholesterolemia?

    <p>Green Tea</p> Signup and view all the answers

    Study Notes

    Manuka Honey

    • Manuka honey is produced from the Manuka tree (Leptospermum scoparium) native to New Zealand.
    • It's known for its distinct flavor and potential health benefits.
    • UMF (Unique Manuka Factor) and MGO (Methylglyoxal) measure the potency of Manuka honey.
    • UMF grades the honey's overall antibacterial activity based on methylglyoxal concentration.
    • A higher UMF number indicates stronger antibacterial activity.
    • MGO directly measures the methylglyoxal concentration in Manuka honey.
    • A higher MGO value also indicates stronger antibacterial activity.
    • Some studies suggest that UMF might provide a more accurate indication of antibacterial activity due to factors beyond methylglyoxal.

    Uses of Manuka Honey

    • Topical application: for wounds, cuts, and skin infections.
    • Oral consumption: to boost immunity, aid digestion, and treat sore throats.
    • Skincare: as a natural moisturizer and anti-inflammatory agent.
    • Recommended dosage is typically 1-2 tablespoons per day.
    • Can be taken directly, mixed with beverages, or applied topically as needed.
    • Consult a healthcare professional before using for medical purposes, especially if you have allergies or other health conditions.

    Insomnia

    • Insomnia is a sleep disorder characterized by difficulty falling asleep, staying asleep, or both despite adequate opportunity for sleep.
    • Common causes include stress, anxiety, medical conditions, and lifestyle factors like irregular sleep schedules, caffeine, or alcohol consumption.
    • Symptoms include difficulty falling asleep, frequent waking during the night, waking up too early, daytime tiredness, irritability, anxiety, concentration difficulties, and memory problems.
    • Treatments include behavioral therapies, prescription medications, and over-the-counter sleep aids.

    Melatonin

    • Melatonin is a natural hormone mainly produced by the pineal gland in the brain.
    • It regulates the sleep-wake cycle and circadian rhythm.
    • Melatonin production decreases with age.
    • The pineal gland receives information from the optic nerve about light levels and adjusts melatonin output accordingly.
    • Melatonin levels increase at night when light decreases, promoting sleep.
    • Light exposure breaks down and suppresses melatonin production.
    • Melatonin plays a crucial role in the sleep-wake cycle, and irregularities can cause sleep problems.
    • Melatonin is generally considered safe.
    • Melatonin is used for:
      • Insomnia, especially delayed sleep phase syndrome and jet lag.
      • Nicotine withdrawal symptoms.
      • Benzodiazepine withdrawal symptoms.
      • Managing cluster headaches.
      • Winter depression.
      • Adjuvant therapy for cancer treatment.
    • Common side effects of melatonin include daytime sleepiness, headache, dizziness, and hypothermia.
    • Melatonin may interact with caffeine, pseudoephedrine, anticoagulants, anti-platelet drugs, NSAIDs, and antihypertensive medications.
    • It's advisable to avoid using melatonin during pregnancy and lactation.

    Ramelteon

    • Ramelteon is a medication for insomnia.
    • It's a selective melatonin receptor agonist, mimicking the effects of melatonin.
    • It binds to receptors in the brain involved in sleep regulation, promoting sleep onset and improving sleep quality.
    • It's primarily prescribed for chronic insomnia, typically for short-term use.
    • It has a low potential for addiction or abuse.
    • Common side effects include dizziness, drowsiness, headache, and nausea.
    • Ramelteon may interact with liver diseases and depressants, especially fluvoxamine.

    Valerian

    • Valerian root is used as a sleep aid and mild nervous system sedative.
    • It relieves anxiety, irritability, and insomnia.
    • It increases GABA activity in the brain, leading to sedative effects.
    • Common side effects include drowsiness, headaches, and stomach upset.
    • Allergic reactions are possible for those sensitive to plants in the valerian family.
    • Recommended dose is 400 to 900 mg of valerian extract up to 2 hours before bedtime.

    Serotonin and Melatonin

    • Serotonin is a precursor to melatonin, meaning the pineal gland converts serotonin into melatonin in the dark.
    • Exposure to bright light increases serotonin levels, promoting wakefulness.
    • Conversely, darkness at night stimulates melatonin production, promoting sleepiness.
    • Imbalances in these hormones can affect mood and sleep, contributing to conditions like depression, anxiety, and insomnia.

    Passionflower

    • Passionflower is considered best for mild to moderate anxiety.
    • It reduces muscle tension and insomnia.
    • It calms nerves.
    • It prevents agitation, mood swings, headaches, and hot flashes from anxiety.
    • It increases GABA activity in the brain.
    • It may interact with serotonin receptors, which are involved in mood regulation and sleep.
    • It has antioxidant properties.
    • Common side effects include drowsiness, stomach upset, and allergic reactions.

    Relaxing Herbal Formula

    • A blend of valerian, catnip, hops, and passionflower extracts.
    • Promotes restful sleep and relaxation.
    • Relieves nervous anxiety.
    • Natural sedative and muscle relaxant.
    • Treats stomach pains and gastrointestinal upset related to anxiety and nervousness, including Irritable Bowel Syndrome (IBS).
    • Synergistic formula of valerian, catnip, hops, and passionflower for combined benefits.

    Jamieson Relaxing Herbal Formula

    • Jamieson Relaxing Herbal Formula is designed to relieve insomnia, reduce nervous tension and anxiety without addiction or habit formation.
    • Each capsule contains Valerian Extract, Catnip Extract, Hops Extract, and Passion Flower Extract.
    • The formula uses specific ratios (4:1 or 5:1) to create the equivalent of a specific amount of raw herb.

    Mechanism of Action

    • Valerian root is a sleep aid, mild nervous system sedative to relieve anxiety, irritability and insomnia.
    • Catnip is a unique herbal anxiety remedy that can treat stomach cramps, spasms and irritations common in anxiety.
    • Hops Strobile is used to relieve gastric spasms due to nervousness. It is also a muscle relaxant and promotes restful sleep.
    • Passionflower is most effective for mild to moderate anxiety. It works by reducing muscle tension and insomnia, calming nerves to prevent agitation, mood swings, headaches, and hot flashes from anxiety.
    • The synergistic formula of Valerian, Catnip, Hops, and Passionflower helps treat stomach pain and gastrointestinal problems related to anxiety, stress and nervousness.

    Benefits and Uses

    • Promotes restful sleep and relaxation.
    • Relieves nervous anxiety.
    • Acts as a natural sedative and muscle relaxant to treat stomach pains and gastrointestinal upset related to anxiety and nervousness.
    • May be helpful for Irritable Bowel Syndrome (IBS).

    Maca

    • Native to the high Andes Mountains of Peru
    • Adaptogen: helps the body adapt to stress
    • Nutritional value: rich in vitamins, minerals, and antioxidants
    • Used to improve fertility, enhance energy, and support hormonal balance

    Uses of Maca

    • Hormone balance: often used to support hormone balance, particularly in women
    • Menopause: may help alleviate symptoms of menopause, such as hot flashes and mood swings
    • Fertility: improve fertility in both men and women
    • Energy and stamina: believed to boost energy levels and enhance athletic performance
    • Mood and cognitive function: may help improve mood, reduce stress, and enhance cognitive function
    • Libido and sexual function: often used as a natural aphrodisiac and may help improve libido and sexual function

    Saffron Supplement

    • Indications: fatigue, anxiety, sleep difficulty, antidepressant, bad mood, stress, PMS, immunity, antioxidant, nervous IBS
    • Helps in the temporary relief of symptoms associated with stress
    • Natural antidepressant: increases serotonin levels
    • Anti-anxiety: relieves stress, bad mood, and sleep difficulty
    • Reduces PMS symptoms: including mood swings, cramps, bloating and acne
    • Antioxidant: reduces inflammation, removes free radicals, delays the effects of aging and cancer
    • Immunity function: increases the number of white blood cells
    • Anti-inflammatory: reduces the level of inflammatory molecules
    • Dose: 1 capsule per day for 3-6 months before breakfast on an empty stomach

    Royal Jelly (Honey Bee Milk)

    • Contains B vitamins (including high levels of B5 and B6), as well as vitamins A, C, D, and E, DNA, minerals, enzymes, hormones, 18 amino acids, gelatin, calcium, copper, iron, phosphorus, potassium, silicon, sulfur, antibacterial and antibiotic components
    • Uses: boost energy, strengthen the immune system, alleviate menopausal symptoms, lower cholesterol levels in people with hyperlipidemia
    • Caution: Be careful with asthmatic patients and those with allergies or dermatitis

    Royal Jelly (Nemr Royal 1000)

    • Nutritive tonic
    • Increase libido
    • Increase physical performance
    • Increase sexual performance
    • Improve sperm quality and motility
    • Increase the immune system
    • Powerful antioxidants

    Maca with Royal Jelly Cross Selling

    • New marriage
    • Planning to have a baby
    • Premature ejaculation therapy
    • Erectile dysfunction therapy
    • Personal lubricant

    Maca

    • Native to the high Andes Mountains of Peru
    • Adaptogen - helps the body adapt to stress.
    • Rich in vitamins, minerals, and antioxidants
    • Used to improve fertility, enhance energy, and support hormonal balance

    Maca Uses

    • Hormone balance: Often used to support hormone balance, particularly in women.
    • Menopause: May help alleviate symptoms of menopause, such as hot flashes and mood swings.
    • Fertility: May improve fertility in both men and women.
    • Energy and stamina: Believed to boost energy levels and enhance athletic performance.
    • Mood and cognitive function: May help improve mood, reduce stress, and enhance cognitive function.
    • Libido and sexual function: Often used as a natural aphrodisiac and may help improve libido and sexual function.

    FluShield™

    • Clinically proven to fight the onset and symptoms of flu, colds and upper-respiratory infections
    • The Only Nutraceutical product in Saudi market with an approved medical claim by SFDA

    FluShield™ Benefits

    • Potent, natural formula helps boost the immune system
    • Fast-acting and free of immune-suppressing isobutylamides
    • Can be taken for the duration of the cold and flu season

    FluShield™ Directions

    • Adults: Take 1 softgel 3 times daily.
    • Consult a health care practitioner for use beyond 2 months.

    FluShield™ Cross-selling Opportunities

    • Common cold medicines: FluShield can be used with other common cold medicines to reduce the severity of symptoms and the duration of treatment.
    • Vitamin C: FluShield can be used for infection prevention, starting one week before potential virus exposure and continuing for one week after.
    • With Antibiotics: Can be used with antibiotics for upper respiratory tract infections.

    Weight Gain

    • Weight gain requires consuming more calories than you burn.
    • Underweight individuals may experience inhibited growth, fragile bones and teeth, a weak immune system, anemia, hair loss, and fertility issues.
    • Tips for Gaining Weight:
      • Eat more frequently.
      • Choose nutrient-rich foods.
      • Try smoothies and shakes.
      • Watch when you drink.
      • Make every bite count.
      • Add extras to your dishes for more calories.
    • Dietary supplements for weight gain:
      • Branched-chain amino acids (valine, leucine, and isoleucine): reduce anorexia and improve nutrition in older, undernourished individuals. Dosage: 4 grams three times daily.
      • Zinc supplement: might help gain weight and improve depression symptoms in individuals with anorexia. Dosage: 100 mg of zinc gluconate daily.
      • Meal replacement shakes: can be a convenient source of calories and nutrients. Dosage: 4 servings with 2 cups of water or milk.

    Biored Forte® Capsules

    • Compositions: Dried Brewer Yeast 600 mg – Conc Fenugreek extract 100 mg.
    • Indications: Low body weight, loss of appetite, improves digestion and stomach health.
    • Features: Natural plant source, Dried Brewer Yeast, Conc. Fenugreek extract.
    • Dried Brewer Yeast: Appetite stimulation, improved digestion, skin, hair, and nail vitality, regulates blood sugar level & cholesterol, treats anemia.
    • Conc. Fenugreek extract: Accelerate the transformation of carbohydrates into fats (lipogenesis). Accelerate the deposition of fats in adipose tissues.
    • Dosage: One tablet twice daily.
    • BMI calculation: BMI = Weight in kilograms / (Height in meters)2

    Obesity Management Guidelines Summary

    • Dietary Modifications: Aim for a 600 kcal daily energy deficit.
    • Physical Activity: Adults should do at least 30 minutes of moderate-intensity exercise five days a week.
    • Preventing obesity may require 45-60 minutes of daily exercise, especially without calorie adjustments.
    • Behavioral Change: Address emotional eating, stress management, and social support.
    • Pharmacological Interventions: Consider medication for those with BMI ≥30 or ≥27 with comorbidities.
    • Surgery: Evaluate as an option for those with BMI ≥40 or ≥35 with comorbidities.

    Weight Management/Weight Reduction Medications

    • Centrally Acting Medications: Saxenda or Victoza (liraglutide), Ozempic (Simaglutide), Mounjaro (Tirzepatide): Mimics GLP-1, a hormone that regulates appetite.
    • Peripherally Acting Medications: Xenical (orlistat): Inhibits lipase, reducing fat absorption.

    Dietary Supplements for Weight Reduction

    • Supplements that impair dietary intake: Fibers (ex. Extra Ananas).
    • Supplements that peripherally act to impair dietary absorption: Chitosan (ex. applefit PLUS).
    • Supplements that increase energy expenditure: Chromium (ex. Jamieson Chromium Chelate), Green Tea, and Caffeine.
    • Others: Garcinia (Hydroxy citric acid, HCA): has a role in preventing fatty acid synthesis and lipogenesis. (ex. Ysana SlimYsana and Garcimium).

    Jamieson CHROMIUM 200 MCG

    • Chromium (HVP chelate) 200 mcg.
    • Benefits:
      • Helps maintain healthy blood sugar levels.
      • Decreases triglycerides and total cholesterol levels while increasing HDL (good) cholesterol levels.
      • Use for weight loss programs and obese patients.
      • Decrease appetite.
      • Prevent from diabetes.
      • Jamieson Chelated Chromium is formulated with vegetable protein for optimal absorption to support healthy glucose metabolism and help metabolize carbohydrates and fats.
    • Directions: Adults: Take 1 tablet daily with a meal.
    • Chromium is helpful in managing obesity and increasing insulin sensitivity.

    Chromium Cross Selling Opportunities

    • Obesity-control medicines that don't contain Chromium. Ex. Xenical and Fatlos.
    • Pre-Diabetic (Obese & has a family history of Diabetes)

    Weight Gain

    • Requires consuming more calories than burned
    • Underweight individuals may experience inhibited growth, fragile bones, weakened immune system, anemia, hair loss, and fertility issues

    Weight Gain Tips

    • Eat more frequently
    • Choose nutrient-rich foods
    • Incorporate smoothies and shakes
    • Be mindful of calorie intake from beverages
    • Maximize calorie density of meals
    • Add additional calories to dishes

    Dietary Supplements for Weight Gain

    • Branched-chain amino acids (BCAAs): reduce anorexia and improve nutrition in older individuals; 4 grams three times daily
    • Zinc supplement: may help gain weight and improve depression symptoms; 100 mg of zinc gluconate daily

    Biored Forte Capsules: Weight Gain

    • Contains dried brewer's yeast and concentrated fenugreek extract
    • Dried brewer's yeast benefits: appetite stimulation, improved digestion, skin/hair/nail health, blood sugar regulation, cholesterol management, anemia treatment
    • Concentrated fenugreek extract benefits: accelerates carbohydrate transformation into fats (lipogenesis), promotes fat deposition in adipose tissue
    • Dosage: one tablet twice daily

    Obesity Management Guidelines

    • Dietary Modifications: aim for a 600 kcal daily energy deficit
    • Physical Activity: adults should engage in at least 30 minutes of moderate-intensity exercise five days a week; preventing obesity may require 45-60 minutes of daily exercise
    • Behavioral Change: address emotional eating, stress management, and social support
    • Pharmacological Interventions: consider medication for individuals with BMI ≥30 or ≥27 with comorbidities
    • Surgery: evaluate as an option for those with BMI ≥40 or ≥35 with comorbidities

    Weight Management Medications

    • Centrally Acting Medications: mimic GLP-1, a hormone that regulates appetite; examples include Saxenda/Victoza (liraglutide), Ozempic (semaglutide), Mounjaro (tirzepatide)
    • Peripherally Acting Medications: inhibit lipase, reducing fat absorption; example: Xenical (orlistat)

    Dietary Supplements for Weight Reduction

    • Supplements that impair dietary intake: fibers, e.g., Extra Ananas
    • Supplements that peripherally act to impair dietary absorption: Chitosan, e.g., applefit PLUS
    • Supplements that increase energy expenditure: Chromium, e.g., Jamieson Chromium Chelate, Green Tea, Caffeine
    • Others: Garcinia (Hydroxy citric acid, HCA): role in preventing fatty acid synthesis and lipogenesis following high-carbohydrate intake, e.g., Ysana SlimYsana and Garcimium

    Jamieson Chromium Chelate

    • Benefits include maintaining healthy blood sugar levels, decreasing triglycerides and total cholesterol levels while increasing HDL (good) cholesterol levels, weight loss support (particularly for obese patients), appetite reduction, diabetes prevention
    • Formulation supports healthy glucose metabolism and helps metabolize carbohydrates and fats
    • Dosage: one tablet daily with a meal

    Chromium Cross-Selling Opportunities

    • Obesity-control medicines without Chromium: e.g., Xenical and Fatlos
    • Pre-Diabetic individuals (obese with a family history of diabetes)

    Women's Health - Pregnancy and Lactation

    • Folic Acid: prevents neural tube defects (NTDs) like spina bifida and anencephaly, may reduce cleft lip and palate risk
    • Iron: prevents iron-deficiency anemia in the mother, ensuring adequate iron for baby's growth and development
    • Calcium and Vitamin D: support bone health in both mother and baby, preventing osteoporosis in the mother and ensuring strong baby bones

    Dietary Supplements for Pregnancy and Lactation

    • Folic acid: at least 400-600 mcg continued during the first month of pregnancy
    • Vitamin C: improves iron absorption
    • Omega-3 Fish Oil: 2.7 g of omega-3 fatty acids from week 18-30 of pregnancy to delivery (essential for baby's eye and brain growth, development, reducing asthma and allergic conditions, preventing premature delivery, and lowering postpartum depression)
    • Pyridoxine (B6): for nausea and vomiting, 25 mg every 8 hours for 72 to 96 hours

    Women's Health - Dysmenorrhea

    • Painful menstrual cramps in the lower abdomen
    • Believed to be caused by excess prostaglandins and leukotrienes, causing uterine contractions

    Dietary Supplements for Dysmenorrhea

    • Fish oil omega-3s: EPA 1080 mg and DHA 720 mg (2 gm fish oil)
    • Vitamin E: 200 IU twice starting 2 days before the menstrual period, continuing through the first 3 days of bleeding
    • Vitamin B1 (Thiamine): 100 mg daily for 90 days to alleviate pain

    Women's Health - Premenstrual Syndrome (PMS)

    • Premenstrual Dysphoric Disorder (PMDD) is a severe form of PMS causing significant emotional and physical symptoms before menstruation

    Symptoms of PMDD

    • Emotional symptoms: depression, anxiety, irritability, anger, mood swings, crying spells
    • Physical symptoms: fatigue, bloating, breast tenderness, abdominal pain, food cravings, headaches

    PMDD Diagnosis

    • Symptoms must be present in the five days before the period for at least three consecutive menstrual cycles
    • Symptoms must end within four days after the period starts
    • Symptoms must interfere with normal activities

    Dietary Supplements for PMS

    • Vitamin D + Calcium + Magnesium + Manganese: significantly reduce depressed mood, water retention, and pain
    • Vitamin E: reduces anxiety, cravings, and depression; dosage: 400 IU daily
    • Brewer's Yeast plus multivitamins
    • Ginkgo Biloba: 80 mg twice daily, starting on the 16th day of the menstrual cycle until the 5th day of the next cycle
    • Vitamin B6: 50-100 mg per day
    • Insufficient evidence: Royal Jelly with Bee pollen

    Jamieson Evening Primrose Oil

    • Natural source of gamma-linolenic acid (GLA) and omega-6 fatty acids
    • Uses: PMS symptoms relief (bloating, breast tenderness, cramps, irritability, mood swings), eczema, diabetic neuropathy, osteoporosis (in combination with fish oil and calcium)

    Cross-Selling Opportunities for Primrose Oil

    • Topical corticosteroids and emollients for treating eczema
    • PMS-symptom relieving medicines

    Jamieson Evening Primrose Oil Features

    • Uses purest and most potent evening primrose seeds grown in Canada
    • Seeds are cold-pressed, and oil is slowly extracted without chemical solvents for maximum potency
    • Formulation guarantees 10% GLA in each capsule (50 mg)
    • Contains vitamin E to prevent rancidity

    Women's Health - Menopause

    • Natural process when ovaries stop producing estrogen, typically around age 51
    • Perimenopause: years leading up to menopause, characterized by fluctuating hormone levels
    • Common Symptoms: hot flashes, sleep problems, vaginal dryness, increased urinary tract infections

    Menopause Treatment Options

    • Hormone therapy: replacing lost estrogen
    • Estrogen receptor modulators: provide estrogen benefits with fewer risks
    • Antidepressants and anti-seizure medications: manage mood swings and hot flashes
    • Local vaginal estrogen: address vaginal dryness and discomfort

    Dietary Supplements for Menopause

    • Soy: reduces hot flushes; 50-120 mg/day of isoflavones
    • St. John's Wort: may improve hot flushes; 300 mg once daily
    • Evening primrose: in combination with fish oil and calcium for treating age-related osteoporosis

    Women's Health - Hair and Skin Health

    • Supplements for Hair Loss: Vitamin B5 (Pantothenic acid), Vitamin B7 (Biotin) in combination with zinc

    Cystine B6 Tablets

    • Ingredients: Cysteine, Zinc, vitamin B6, Arginine
    • Indications: hair loss, hair density, shiny hair, nail health
    • Dosage: 2 tablets twice daily for 3 months

    Cystine B6 Benefits

    • Cysteine: transports essential minerals (iron and zinc) for hair regrowth, strengthens hair, prevents hair curls, protects hair from damage, reduces frizz and adds shine, does not increase body weight
    • Zinc: deficiency can lead to changes in hair follicle protein structure, weakening hair follicles, resulting in increased hair loss
    • Vitamin B6: binds to testosterone receptors, preventing DHT formation
    • Arginine: supports blood flow and hair growth

    Supplements for Wrinkles and Whitening

    • Glutathione (Gluta500 Tab, Gluta Maxx)
    • Pycnogenol for 3 months (Pycnox tab)

    Acne Supplement

    • Zinc (oral and topical): 30-130 mg elemental zinc daily (10 mg Jamieson Zinc (elemental) = 77.6 mg of Zinc Gluconate)

    Weight Gain

    • Requires consuming more calories than you burn.
    • Underweight individuals may experience inhibited growth, fragile bones, weakened immune system, anemia, hair loss, and fertility issues.
    • Tips for weight gain include; eating more frequently, choosing nutrient-rich foods, consuming smoothies and shakes, making every bite count, and adding extras to your dishes for more calories.

    Supplements for Weight Gain

    • Branched-chain amino acids may help reduce anorexia and improve nutrition in older undernourished people. Dose: 4 grams 3 times daily.
    • Zinc supplement may help gain weight and reduce depression symptoms in people with anorexia. Dose: 100 mg of zinc gluconate daily.
    • Meal replacement shakes like Ensure Max and Serious Mass are recommended. Dose: 4 servings mixed with 2 cups of water or milk.

    Biored Forte® Capsules

    • Composition: Dried Brewer Yeast 600 mg – Conc Fenugreek extract 100 mg.
    • Indications: Low body weight, loss of appetite, improved digestion, and stomach health.
    • Features: Natural plant source, Dried Brewer Yeast, Conc.Fenugreek extract
    • Dried Brewer Yeast: stimulates appetite, improves digestion, enhances skin, hair, and nail vitality, regulates blood sugar level and cholesterol, treats anemia.
    • Conc.Fenugreek extract: Accelerates transformation of carbohydrates into fats (lipogenesis) and deposition of fats in adipose tissues.
    • Dose: One tablet twice daily.

    Obesity Management Guidelines Summary

    • Dietary Modifications: Aim for a 600 kcal daily energy deficit.
    • Physical Activity: Adults should do at least 30 minutes of moderate-intensity exercise five days a week. Preventing obesity may require 45-60 minutes of daily exercise, especially without calorie adjustments.
    • Behavioral Change: Address emotional eating, stress management, and social support.
    • Pharmacological Interventions: Consider medication for those with BMI ≥30 or ≥27 with comorbidities.
    • Surgery: Evaluate as an option for those with BMI ≥40 or ≥35 with comorbidities.

    Weight Management/Weight Reduction Medications

    • Centrally Acting Medications: Saxenda or Victoza (liraglutide), Ozempic (Simaglutide), Mounjaro (Tirzepatide): Mimics GLP-1, a hormone that regulates appetite.
    • Peripherally Acting Medications: Xenical (orlistat): Inhibits lipase, reducing fat absorption.

    Dietary Supplements for Weight Reduction

    • Supplements that impair dietary intake: Fibers, ex. Extra Ananas
    • Supplements that peripherally act to impair dietary absorption: Chitosan ex. applefit PLUS
    • Supplements that increase energy expenditure: Chromium ex. Jamieson Chromium Chelate, Green Tea and Caffeine.
    • Others: Garcinia ex. Ysana SlimYsana and Garcimium: Contains Hydroxy citric acid (HCA) which plays a role in preventing fatty acid synthesis and lipogenesis following ingestion of a high carbohydrate diet.

    Jamieson CHROMIUM 200 MCG

    • Contains Chromium (HVP chelate) 200 mcg, for optimal absorption to support healthy glucose metabolism and help metabolize carbohydrates and fats.
    • Benefits:
      • Helps maintain healthy blood sugar levels
      • Decreases triglycerides and total cholesterol levels while increasing HDL (good) cholesterol levels.
      • Used for weight loss programs and obese patients
      • Decreases appetite
      • Prevents diabetes
    • Directions: Adults: Take 1 tablet daily with a meal. Chromium is helpful in managing OBESITY and increasing insulin-sensitivity.

    Chromium Cross-selling Opportunities

    • Obesity-control medicines that don't contain Chromium. Ex. Xenical and Fatlos.
    • Pre-Diabetic (Obese and has a family history of Diabetes)

    Women's Health/Pregnancy and Lactation

    • Folic Acid: Prevents neural tube defects (NTDs) like spina bifida and anencephaly, may also reduce the risk of cleft lip and palate.
    • Iron: Prevents iron-deficiency anemia in the mother, which can lead to fatigue, weakness, and other health problems, ensures the baby receives adequate iron for growth and development, especially important for premature and low-birth-weight infants.
    • Calcium and Vitamin D: Support bone health in both the mother and baby, adequate intake is essential for preventing osteoporosis in the mother and ensuring strong bones in the baby.

    Dietary Supplements for Pregnancy and Lactation (Prenatal Vitamins)

    • Folic acid: Dose at least 400-600 mcg continued during the 1st month of pregnancy.
    • Vitamin C: Improves iron absorption.
    • Omega-3 Fish Oil: 2.7g of omega-3 fatty acids from week 18-30 pregnancy till delivery, essential for baby's eye and brain growth, early development, reduces chances of asthma and allergic conditions, prevents premature delivery, lowers postpartum depression.
    • Pyridoxine (B6): 25 mg every 8 hours for 72 to 96 hours, used for nausea and vomiting.

    Women's Health/Dysmenorrhea

    • Dysmenorrhea is a medical term used to describe painful menstrual cramps in the lower abdomen.
    • It's believed to be caused by excessive or imbalanced levels of prostaglandins and leukotrienes, substances that cause contractions in the uterus.
    • These contractions can lead to pain and discomfort during menstruation.

    Dietary Supplements for Dysmenorrhea

    • Fish oil omega-3s: EPA 1080 mg and DHA 720 mg (2 gm fish oil).
    • Vitamin E: 200 IU twice starting 2 days before the menstrual period and continuing through the first 3 days of bleeding
    • Vitamin B1 (Thiamine): 100 mg daily for 90 days stops pain.

    Women's Health/Premenstrual Syndrome (PMS)

    • Premenstrual Dysphoric Disorder (PMDD) is a severe form of PMS that causes significant emotional and physical symptoms during the days leading up to a woman's menstrual period.

    Symptoms of PMDD

    • Emotional symptoms: Depression, anxiety, irritability, anger, mood swings, crying spells.
    • Physical symptoms: Fatigue, bloating, breast tenderness, abdominal pain, food cravings, headaches.

    Diagnosis of PMDD

    • Symptoms must be present in the five days before the period for at least three consecutive menstrual cycles.
    • Symptoms must end within four days after the period starts.
    • Symptoms must interfere with some of the woman's normal activities.

    Dietary Supplementation for PMS

    • Vitamin D + Calcium + Magnesium + Manganese: Significantly reduce depressed mood, water retention, and pain.
    • Vitamin E: Reduces anxiety, craving, and depression. Dose: 400 IU daily.
    • Brewer’s Yeast plus multivitamins.
    • Ginkgo Biloba: 80 mg twice daily, starting on the 16th day of the menstrual cycle until the 5th day of the next cycle.
    • Vitamin B6: 50-100 mg per day.
    • Insufficient evidence: Royal Jelly with Bee pollen.

    Jamieson Evening Primrose Oil

    • An important natural source of Gamma linolenic acid (GLA) and Omega 6 fatty acids.

    Uses of Primrose Oil

    • PMS (Pre-Menstrual Syndrome): Relief of PMS symptoms (bloating, breast tenderness, abdominal cramps, irritability, and mood swings)
    • Eczema
    • Diabetic Neuropathy
    • Osteoporosis with fish oil and Calcium

    Cross-selling Opportunities of Primrose Oil

    • Topical Corticosteroids & Emolients for treating Eczema.
    • PMS-symptoms relieving medicines.

    Why Jamieson Evening Primrose Oil?

    • Uses purest and most potent evening primrose seeds grown in Canada.
    • Seeds are cold-pressed and the oil is slowly extracted without the use of chemical solvents to ensure max potency.
    • Formulation guarantees 10% of GLA in each capsule (50 mg).
    • Contains Vit.E to help prevent rancidity of EPO.

    Women's Health/Menopause

    • Menopause is a natural biological process that occurs in women when their ovaries stop producing estrogen.
    • This typically happens around the age of 51.
    • The years leading up to menopause, characterized by fluctuating hormone levels, are known as perimenopause.

    Common Symptoms of Menopause:

    • Hot flashes: Sudden sensations of heat and sweating.
    • Sleep problems: Insomnia, night sweats, and difficulty falling asleep.
    • Vaginal dryness: Can lead to discomfort during sex.
    • Increased urinary tract infections: Due to changes in the vaginal environment.

    Treatment Options

    • Hormone therapy: Replacing lost estrogen can help alleviate many menopausal symptoms.
    • Estrogen receptor modulators: Can provide some of the benefits of estrogen without the same risks.
    • Antidepressants and anti-seizure medications: May help manage mood swings and hot flashes.
    • Local vaginal estrogen: Can address vaginal dryness and discomfort

    Dietary Supplements for Menopause

    • Soy: Help reducing hot flushes, 50-120 mg/day of isoflavones.
    • St.John's Wort: It might help improve hot flushes with 300 mg once daily.
    • Evening primrose in combination with fish oil and calcium for treating age-related Osteoporosis.

    Women's Health/Hair and Skin Health

    Supplements for Hair Loss:

    • Vitamin B5 (Pantothenic acid)
    • Vitamin B7 (Biotin) in combination with Zinc.

    Cystine B6® Tablets:

    • Ingredients: Cysteine, Zinc, Vitamin B6, Arginine
    • Indications: Hair loss, hair density, shiny hair, nail health.
    • Dosage: 2 tablets/ twice daily for 3 months

    Features and Benefits:

    • Cysteine:
      • Transports two essential minerals (iron and zinc) that are vital nutrients for hair regrowth.
      • Strengthens the hair and makes them straight.
      • Prevents hair waves and curls.
      • Protects hair from damage.
      • Decreases frizz and adds shine.
      • Doesn’t increase body weight.
    • Zinc:
      • Deficiency causes changes in the protein structure of hair follicles leading to weakening of their structural integrity.
      • Means new hairs will fall off quicker than they should.
    • Vitamin B6:
      • Vitamin B6 binds to the testosterone receptors and stops the formation of DHT.
    • Arginine:
      • Supports blood flow and hair growth.

    Supplements for Wrinkles and Whitening

    • Glutathione (Gluta500 Tab, Gluta Maxx)
    • Pycnogenol for 3 months (Pycnox tab)

    Acne Supplement

    • Zinc (oral and topical): Orally with doses of 30-130 mg elemental zinc daily. (10 mg Jamieson Zinc (elemental) = 77.6 mg of Zinc Gluconate (The most highly absorbable salt from zinc)
    • Co-enzyme Q10: 60 mg twice daily.
    • Vitamin C: 500 mg daily in addition to regular antihypertensive drugs

    Hypertension

    • Garlic: Decreases blood pressure, systolic by 16 mmHg and diastolic by 9 mmHg. 600 - 1200 mg daily divided into 3 doses.
    • Fish Oil: Reduces systolic blood pressure by 3.4-5.5 mmHg and diastolic blood pressure by 2.0-3.5 mmHg in individuals with hypertension. 2-4g of omega-3 fatty acids daily for up to one year.
    • Cod liver oil: 20 ml daily. 20 ml cod liver oil that on average contains 1.8 grams EPA, 2.2 grams DHA, 15,000 IU vitamin A, and 1500 IU vitamin D.
    • Co-enzyme Q10: 120-200 mg per day divided into 2 doses
    • Calcium: 1000-1500 mg daily
    • Hibiscus: 240mL tea containing 1.25-2g of Hibiscus Calyx (6-30 minutes in boiling water) 1-3 times daily for 4-6 weeks.

    Dietary Supplements for Hypercholesterolemia

    • Likely Effective:
      • Green Tea: 3-10 cups OR 1-3 caps daily.
    • Possibly Effective:
      • Calcium carbonate: 400 mg three times daily reduces low-density lipoprotein (LDL) cholesterol by 4.4% and increases high-density lipoprotein (HDL) by 4.1% after 6 weeks of treatment (American Heart Association Step 1).
      • Magnesium: Calcium 1200 mg plus vitamin D 400 reduces the total cholesterol: HDL ratio and the LDL: HDL. In addition, it is supportive for patients suffering from Statin-induced myalgia.
      • Chromium: 15-200 mcg daily for 6-12 weeks decreases low-density lipoprotein (LDL) cholesterol and total cholesterol.
      • Artichoke: Modestly reduces total and low-density lipoprotein (LDL) cholesterol, and the LDL/high density lipoprotein (HDL) ratio over 6 to 12 weeks of treatment.
    • Insufficient Reliable Evidence To Rate:
      • Royal Jelly: 30-150mg for 4-6 weeks.
      • Vitamin C: 500 mg daily for at least 4 weeks reduces low-density lipoprotein (LDL) cholesterol by 7.9 mg/dL and reduces triglycerides by 20.1 mg/dL.
      • Brewer’s yeast: 5-30g of brewer's yeast containing 23-50mcg of chromium for 8-12 weeks may decrease the levels of total cholesterol and can increase levels of high-density lipoprotein (HDL)-cholesterol.
      • Black seed.

    For Statin-induced myopathy

    • Coenzyme Q10 dose (100-200 mg daily for 3 months).
    • Calcium plus Vitamin D.

    Coenzyme Q10 (Co Q10) Uses

    • Diabetic neuropathy: Dose 400mg daily for 12 weeks
    • Hypertension: Dose 100 to 120 mg daily
    • Prevent migraine headache: Dose 100 mg TID for 3 months
    • Male infertility: Dose 200 to 300 mg daily for 6 months
    • Improve Fibromyalgia
    • Reduce pre-eclampsia

    Dietary Supplements for Hypertriglyceridemia

    • Effective:
      • Fish oil: Fish oils are thought to lower triglycerides by decreasing secretion of VLDL, increasing VLDL apolipoprotein B secretion, and possibly by increasing VLDL clearance, decreasing VLDL size, and reducing triglyceride transport. The effect is dose-dependent (higher doses have greater effects), 2-4 gm of omega-3 fatty acids daily for 12 – 24 weeks, eg. Omacor (FDA approved).
    • Likely Effective:
      • Green Tea
      • Cod liver oil
    • Insufficient Reliable Evidence To Rate:
      • Vitamin B12.

    Dietary Supplements for Male Infertility:

    • Vitamin E: This antioxidant may help improve sperm quality and motility.
    • L-Carnitine: A naturally occurring compound that can boost sperm count and movement.
    • Acetyl L-carnitine: In combination with L-carnitine, this supplement may further enhance sperm quality.
    • CoQ10: This antioxidant can potentially improve sperm motility and density.
    • Zinc: When combined with other antioxidants, zinc may contribute to increased sperm count.
    • Horse chestnut: Increases sperm density in men with varicocele-associated infertility. It may not improve sperm motility.

    Vit E (Alpha-tocopherol)

    • Is the most active form in humans.
    • Found in eggs, fortified cereals, fruit, green leafy vegetables (such as spinach), meat, etc.
    • Has antioxidant effect.
    • Cardioprotective: Inhibits oxidation of (LDL) cholesterol and through the inhibition of platelet aggregation.
    • Enhances immune system.

    Drug-Drug Interactions

    • Anticoagulant/Antiplatelet drugs, e.g. aspirin, clopidogrel, dalteparin, enoxaparin, heparin and warfarin (added bleeding effect).

    Vitamin E Uses

    • Dementia (with Vit C): Dose 800 – 2000 IU/day.
    • Alzheimer’s disease.
    • Dysmenorrhea: Dose 200 IU twice daily or 500 IU starting 2 days before menstruation and continuing through the first 3 days of bleeding.
    • Premenstrual syndrome (PMS).
    • Physical performance and muscle strength in elderly patients.
    • Rheumatoid arthritis (reduce pain but not inflammation).
    • Infertility (asthenospermia or oligoasthenospermia with dose 200 – 600 IU daily).

    Dietary Supplements for Erectile dysfunction

    • Panax Ginseng: This herbal supplement may help improve blood flow and erectile function.
    • L-Arginine: An amino acid that can support blood flow and nitric oxide production, which are essential for erections.
    • L-Arginine Drug Interactions:
      • Avoid With Nitrates, PDE 5 inhibitors (Viagra, Cialis, Levitra), Anti-hypertensive drugs.
      • Avoid in recent heart attack, kidney malfunction, Herpes infection, and surgery.
    • Yohimbine: While it may improve erectile function in some cases, it's important to use it with caution and under medical supervision due to potential side effects and interactions with other medications.
    • Yohimbine Drug Interactions:
      • Avoid With Tricyclic antidepressant, antihypertensives, pseudoephedrine.
      • Avoid in recent Bleeding disorders, prostate, psychological problems e.g. anxiety, depression.

    Medications used for BPH:

    • Alpha blockers e.g., Cardura, Xatra
    • Phosphodiesterase-5 inhibitors Tadalafil may relax smooth muscles in the lower urinary tract in addition to ED treatment.
    • 5-alpha reductase inhibitors e.g., Finasteride and Dutasteride

    Dietary Supplements for BPH

    • Pumpkin Seeds: Rich in phytosterols, pumpkin seeds may help reduce prostate inflammation and improve urinary flow.
    • Saw Palmetto: This herbal extract has been used traditionally to treat BPH symptoms. It may help reduce prostate size and improve urinary function.
    • Garlic: While some studies suggest garlic may be beneficial for BPH symptoms, more research is needed to confirm its effectiveness.

    Weight Gain

    • Weight gain requires consuming more calories than you burn.
    • Underweight individuals may experience inhibited growth, fragile bones and teeth, a weak immune system, anemia, hair loss, and fertility issues.
    • Tips for gaining weight include eating more frequently, choosing nutrient-rich foods, incorporating smoothies and shakes, being mindful of beverage consumption, maximizing every bite, and adding extras to dishes for calorie increase.

    Dietary Supplements for Weight Gain

    • Branched-chain amino acids (BCAA) like valine, leucine, and isoleucine can reduce anorexia and improve nutrition in older, undernourished individuals. The recommended dosage is 4 grams three times daily.
    • Zinc supplements may promote weight gain and alleviate depression symptoms in individuals with anorexia. The recommended dosage is 100 mg of zinc gluconate daily.

    Biored Forte

    • Biored Forte capsules contain dried brewer's yeast and concentrated fenugreek extract.
    • Indications for use include low body weight, loss of appetite, improved digestion, and stomach health.
    • Dried brewer's yeast stimulates appetite and improves digestion, promotes skin, hair, and nail vitality, regulates blood sugar levels and cholesterol, and treats anemia.
    • Concentrated fenugreek extract accelerates the transformation of carbohydrates into fats (lipogenesis) and promotes fat deposition in adipose tissues.
    • The recommended dosage is one tablet twice daily.

    Obesity Management Guidelines Summary

    • Dietary modifications should aim for a 600 kcal daily energy deficit.
    • Adults should engage in at least 30 minutes of moderate-intensity exercise five days a week. Preventing obesity might require 45-60 minutes of daily exercise, especially without calorie adjustments.
    • Behavioral changes address emotional eating, stress management, and social support.
    • Pharmacological interventions may be considered for individuals with a BMI ≥30 or ≥27 with comorbidities.
    • Surgery can be evaluated as an option for those with a BMI ≥40 or ≥35 with comorbidities.

    Weight Management/Weight Reduction Medications

    • Centrally acting medications (Saxenda, Victoza, Ozempic, Mounjaro) mimic GLP-1, a hormone that regulates appetite.
    • Peripherally acting medications (Xenical) inhibit lipase, reducing fat absorption.

    Dietary Supplements for Weight Reduction

    • Supplements that impair dietary intake include fibers like Extra Ananas.
    • Supplements that act peripherally to impair dietary absorption include chitosan like applefit PLUS.
    • Supplements that increase energy expenditure include chromium like Jamieson Chromium Chelate, green tea, and caffeine.
    • Other supplements like Garcinia (Hydroxy citric acid, HCA) play a role in preventing fatty acid synthesis and lipogenesis following high-carbohydrate diet consumption. Examples include Ysana SlimYsana and Garcimium.

    Jamieson CHROMIUM 200 MCG

    • Chromium (HVP chelate) helps manage obesity, increases insulin sensitivity, and supports healthy glucose metabolism.
    • It aids in carbohydrate and fat metabolism.
    • The recommended dosage is one tablet daily with a meal.

    Chromium Cross-Selling Opportunities

    • Obesity control medicines not containing chromium like Xenical and Fatlos.
    • Pre-diabetic individuals (obese and with a family history of diabetes).

    Women's Health/Pregnancy and Lactation

    • Folic acid helps prevent neural tube defects like spina bifida and anencephaly. It may also reduce the risk of cleft lip and palate.
    • Iron prevents iron-deficiency anemia in the mother, which can lead to fatigue, weakness, and other health problems. It ensures adequate iron for the baby's growth and development, especially crucial for premature and low-birth-weight infants.
    • Calcium and vitamin D support bone health in both the mother and baby. Adequate intake is essential for preventing osteoporosis in the mother and ensuring strong bones in the baby.

    Dietary Supplements for Pregnancy and Lactation (Prenatal Vitamins)

    • Folic acid (dose at least 400-600 mcg continued during the first month of pregnancy).
    • Vitamin C for improved iron absorption.
    • Omega-3 fish oil (2.7g of omega-3 fatty acids from week 18-30 of pregnancy until delivery), essential for baby's eye and brain growth, early development, reduced risk of asthma or allergic conditions, prevention of premature delivery, and lower postpartum depression.
    • Pyridoxine (B6) for nausea and vomiting, 25 mg every 8 hours for 72 to 96 hours.

    Women's Health/Dysmenorrhea

    • Dysmenorrhea is painful menstrual cramps in the lower abdomen, caused by an excess or imbalance of prostaglandins and leukotrienes, which cause uterine contractions.

    Dietary Supplements for Dysmenorrhea

    • Fish oil omega-3s (EPA 1080 mg and DHA 720 mg - 2 gm of fish oil).
    • Vitamin E (200 IU twice daily starting 2 days before the menstrual period and continuing through the first 3 days of bleeding).
    • Vitamin B1 (Thiamine) (100 mg daily for 90 days).

    Women's Health/Premenstrual Syndrome (PMS)

    • Premenstrual Dysphoric Disorder (PMDD) is a severe form of PMS causing significant emotional and physical symptoms during the days leading up to a woman’s menstrual period.

    Symptoms of PMDD

    • Emotional symptoms: Depression, anxiety, irritability, anger, mood swings, crying spells.
    • Physical symptoms: Fatigue, bloating, breast tenderness, abdominal pain, food cravings, and headaches.

    Diagnosis of PMDD

    • Symptoms must be present in the five days before the period for at least three consecutive menstrual cycles.
    • Symptoms must end within four days after the period starts.
    • Symptoms must interfere with some of the woman's normal activities.

    Dietary Supplements for PMS

    • Vitamin D + Calcium + Magnesium + Manganese: Significantly reduce depressed mood, water retention, and pain.
    • Vitamin E: Reduces anxiety, craving, and depression with a dose of 400 IU daily.
    • Brewer's yeast plus multivitamins.
    • Ginkgo Biloba: 80 mg twice daily, starting on the 16th day of the menstrual cycle until the 5th day of the next cycle.
    • Vitamin B6: 50-100 mg per day.
    • Royal Jelly with Bee pollen (insufficient evidence to rate).

    Jamieson Evening Primrose Oil

    • Jamieson Evening Primrose Oil is a natural source of Gamma linolenic acid (GLA) and Omega 6 fatty acids.

    Uses of Primrose Oil

    • PMS (Pre-menstrual Syndrome): Relief of PMS symptoms (bloating, breast tenderness, abdominal cramps, irritability, and mood swings).
    • Eczema.
    • Diabetic neuropathy.
    • Osteoporosis in combination with fish oil and calcium.

    Cross-selling Opportunities of Primrose Oil

    • Topical corticosteroids and emollients for treating eczema.
    • PMS symptom-relieving medicines.

    Women's Health/Menopause

    • Menopause is a natural process where ovaries stop producing estrogen, typically around 51 years old. The years leading up to menopause are called perimenopause with fluctuating hormone levels.

    Common Symptoms of Menopause

    • Hot flashes: Sudden sensations of heat and sweating.
    • Sleep problems: Insomnia, night sweats, and difficulty falling asleep.
    • Vaginal dryness: Can lead to discomfort during sexual relations.
    • Increased urinary tract infections due to changes in vaginal environment.

    Treatment Options

    • Hormone therapy: Replacing lost estrogen can alleviate menopausal symptoms.
    • Estrogen receptor modulators: Provide benefits of estrogen without the same risks.
    • Antidepressants and anti-seizure medications: Can manage mood swings and hot flashes.
    • Local vaginal estrogen: Addresses vaginal dryness and discomfort.

    Dietary Supplements for Menopause

    • Soy: Helps reduce hot flushes, 50-120 mg/day of isoflavones.
    • St. John’s wort: Might improve hot flushes with 300 mg once daily.
    • Evening primrose in combination with fish oil and calcium for treating age-related Osteoporosis.

    Women's Health/Hair and Skin Health

    Supplements for Hair Loss

    • Vitamin B5 (Pantothenic acid).
    • Vitamin B7 (Biotin) in combination with Zinc.

    Cystine B6® Tablets

    • Ingredients: Cysteine, Zinc, Vitamin B6, Arginine.
    • Indications: Hair loss, hair density, shiny hair, and nail health.
    • Dosage: 2 tablets twice daily for 3 months.

    Supplements for Wrinkles and Whitening

    • Glutathione (Gluta500 Tab, Gluta Maxx).
    • Pycnogenol for 3 months (Pycnox tab).

    Acne Supplement

    • Zinc (oral and topical) orally with doses of 30-130 mg elemental zinc daily (10 mg Jamieson Zinc (elemental) = 77.6 mg of Zinc Gluconate).
    • Co-enzyme Q10: 60 mg twice daily.
    • Vitamin C: 500 mg daily in addition to regular antihypertensive drugs.

    Garlic

    • Decreases blood pressure, systolic by 16 mmHg and diastolic by 9 mmHg. Dosage: 600 – 1200 mg daily divided into 3 doses.

    Fish Oil

    • Reduces systolic blood pressure by 3.4-5.5 mmHg and diastolic blood pressure by 2.0-3.5 mmHg in individuals with hypertension. Dosage: 2-4g of omega-3 fatty acids daily for up to one year.

    Cod Liver Oil

    • Dosage: 20 ml daily. 20 ml cod liver oil contains 1.8 grams EPA, 2.2 grams DHA, 15,000 IU vitamin A, and 1500 IU vitamin D.

    Co-enzyme Q10

    • Dosage: 120-200 mg per day divided into 2 doses.

    Calcium

    • Dosage: 1000 – 1500 mg daily.

    Hibiscus

    • Dosage: 240mL tea containing 1.25-2g of Hibiscus Calyx (6-30 minutes in boiling water) 1-3 times daily for 4-6 weeks.

    Dietary Supplements for Hypercholesterolemia

    Likely Effective

    • Green Tea: 3 – 10 cups OR 1-3 caps daily.

    Possibly Effective

    • Calcium carbonate 400 mg three times daily reduces LDL cholesterol by 4.4% and increases HDL by 4.1% after 6 weeks of treatment (American Heart Association Step 1).
    • Magnesium: calcium 1200 mg plus vitamin D 400 reduces the total cholesterol: HDL ratio and the LDL: HDL. In addition, it supports patients suffering from statin-induced myalgia.
    • Chromium: 15-200 mcg daily for 6-12 weeks decreases LDL cholesterol and total cholesterol.
    • Artichoke (الخرشوف): Modestly reduces total and LDL cholesterol and the LDL/HDL ratio over 6 to 12 weeks of treatment.

    Insufficient Reliable Evidence to Rate

    • Royal Jelly: 30-150mg for 4-6 weeks.
    • Vitamin C: 500 mg daily for at least 4 weeks reduces LDL cholesterol by 7.9 mg/dL and reduces triglycerides by 20.1 mg/dL.
    • Brewer’s yeast: 5-30g of brewer's yeast containing 23-50mcg of chromium for 8-12 weeks may decrease total cholesterol and increase HDL-cholesterol levels.
    • Black seed.

    For Statin-induced Myopathy

    • Coenzyme Q10 (100-200 mg daily for 3 months).
    • Calcium plus vitamin D.

    Coenzyme Q10 (Co Q10) Uses

    • Diabetic neuropathy: 400mg daily for 12 weeks.
    • Hypertension: 100 to 120 mg daily.
    • Prevent migraine headache: 100 mg thrice daily for 3 months.
    • Male infertility: 200 to 300 mg daily for 6 months.
    • Improve Fibromyalgia.
    • Reduce pre-eclampsia.

    Dietary Supplements for Hypertriglyceridemia

    Effective

    • Fish oil: thought to lower triglycerides by decreasing secretion of VLDL, increasing VLDL apolipoprotein B secretion. The effect is dose-dependent, with higher doses having greater effects. Dosage: 2-4 gm of omega-3 fatty acids daily for 12 – 24 weeks, e.g. Omacor (FDA approved).

    Likely Effective

    • Green Tea.
    • Cod liver oil.

    Insufficient Reliable Evidence to Rate

    • Vitamin B12.

    Dietary Supplements for Male Infertility

    • Vitamin E: This antioxidant can improve sperm quality and motility.
    • L-Carnitine: A naturally occurring compound that can boost sperm count and movement.
    • Acetyl L-carnitine: In combination with L-carnitine, this supplement can enhance sperm quality.
    • CoQ10: A potential improver of sperm motility and density.
    • Zinc: When combined with other antioxidants, zinc can contribute to increased sperm count.
    • Horse chestnut: Increase sperm density in men with varicocele-associated infertility, but may not improve sperm motility.

    Vit E (Alpha-tocopherol)

    • Found in eggs, fortified cereals, fruits, green leafy vegetables, and meat. Possesses antioxidant, cardioprotective, and immune-enhancing effects.

    Drug Drug Interactions

    • Anticoagulant/Antiplatelet drugs e.g.aspirin, clopidogrel, dalteparin, enoxaparin, heparin, and warfarin (added bleeding effect).

    Vitamin E Uses

    • Dementia (with Vitamin C): 800 – 2000 IU/day.
    • Alzheimer’s disease.
    • Dysmenorrhea: 200 IU twice daily or 500 IU daily starting 2 days before menstruation and continuing through the first 3 days of bleeding.
    • Premenstrual syndrome (PMS).
    • Physical performance and muscle strength in elderly patients.
    • Rheumatoid arthritis (reduce pain but not inflammation).
    • Infertility (asthenospermia or oligoasthenospermia): 200 – 600 IU daily.

    Dietary Supplements for Erectile Dysfunction

    • Panax Ginseng: This herbal supplement can improve blood flow and erectile function.
    • L-Arginine: An amino acid that supports blood flow and nitric oxide production, which are essential for erections.
    • Yohimbine: Improves erectile function in some cases, but use it with caution and under medical supervision due to potential side effects and interactions.

    Drug Interactions of L-Arginine

    • Avoid with nitrates, PDE 5 inhibitors (Viagra, Cialis, Levitra), Anti-hypertensive drugs.
    • Avoid in recent heart attack, kidney malfunction, Herpes infection, and surgery.

    Drug Interactions of Yohimbine

    • Avoid with tricyclic antidepressant, antihypertensives, and pseudoephedrine.
    • Avoid in recent bleeding disorders, prostate issues, and psychological problems like anxiety and depression.

    Medications Used for BPH

    • Alpha blockers (e.g. Cardura, Xatra).
    • Phosphodiesterase-5 inhibitors (Tadalafil) relax smooth muscles in the lower urinary tract, along with ED treatment.
    • 5-alpha reductase inhibitors (e.g. Finasteride and Dutasteride).

    Dietary Supplements for BPH

    • Pumpkin Seeds: Rich in phytosterols, they can reduce prostate inflammation and improve urinary flow.
    • Saw Palmetto: Traditionally used to treat BPH symptoms, it may help reduce prostate size and improve urinary function.
    • Garlic: Some studies suggest potential benefit for BPH, but further research is needed.

    Vitamin D Levels (25-hydroxyvitamin D)

    • Deficient: 250 nmol/L.

    Vitamin D Doses

    • Vitamin D deficient patients: 50,000 IU once weekly for 8 weeks, then 1000 IU/d daily for maintenance.
    • Vitamin D inadequate patients: 5000 IU/d daily for 4-6 weeks, then 1000 IU/d daily for maintenance.
    • Vitamin D adequate: 1000 IU/d for maintenance.

    Fat-Soluble Vitamins / Vitamin D

    • Regulates calcium and phosphorus absorption in the intestines.
    • Maintains strong bones and teeth.
    • Supports immune function.

    Vit D Drug Drug Interactions

    • Aluminum (Antacids): Take vitamin D 2 hrs before or 4 hours after antacids (may increase Al absorption).
    • Digoxin (Lanoxin): May cause fatal cardiac arrhythmia in high doses.
    • Diltiazem.Verapamil.
    • Thiazide diuretics: Cause hypercalcemia.

    Vit D Required Daily Intake

    • Generally recommended daily intake for adults: 400-800 International Units (IUs).

    High Dose Vit D Side Effects

    • Hypercalcemia (excess calcium in the blood).
    • Kidney stones.
    • Nausea.
    • Vomiting.
    • Weakness.

    Jamieson™ D3 Tab

    • Formulated with Quali®-D, the world's premium, natural vitamin D3. Fully sustainable and traceable from farm to finish.
    • Manufactured using a 360 pure process.

    Indications

    • Essential for normal development and maintenance of bones and teeth.
    • Helps in the absorption and use of calcium and phosphorus in the body.
    • Prevents vitamin D deficiency.

    Vitamin E

    • Vit E (Alpha-tocopherol): is the most active form found in eggs, fortified cereals, fruit, green leafy vegetables, and meat.

    Vitamin E Uses

    • Dementia (with Vitamin C): 800-2000 IU/d.
    • Alzheimer's disease.
    • Dysmenorrhea: Reduce menstrual pain severity and duration, decrease blood loss (200 IU twice daily or 500 IU daily starting 2 days before menstruation and continuing through the first 3 days of bleeding).
    • Premenstrual syndrome (PMS).
    • Physical performance and muscle strength in elderly people.
    • Rheumatoid arthritis: Reduce pain but not inflammation.
    • Infertility (asthenospermia or oligoasthenospermia): 200-600 IU daily.
    • Antioxidant effect (cardioprotective effect): Inhibiting oxidation of (LDL) cholesterol and through the inhibition of platelet aggregation.
    • Enhance immune system.

    Vit E Drug Drug Interactions

    • Anticoagulant/Antiplatelet: Drugs, e.g. aspirin, clopidogrel, dalteparin, enoxaparin, heparin, and warfarin. Increased bleeding effect.

    Vit E Effect

    • Antioxidant effect.
    • Cardioprotective: Inhibiting oxidation of (LDL) cholesterol and through the inhibition of platelet aggregation.
    • Enhance immune system.

    Calcium (Ca)

    • Essential part of bones and teeth. The heart, nerves, and blood-clotting systems also need calcium to work. Found in eggs, fortified cereals, fruit, green leafy vegetables (such as spinach), meat, etc.

    Uses of Calcium

    • Dyspepsia (Antacids: Carbonate).
    • Hypocalcemia.
    • Increases fetal bone mineralization and density (during pregnancy).
    • Fall prevention in older people (Ca+Vit D).
    • Premenstrual Syndrome (PMS): Significantly reduce depressed mood, water retention, and pain associated with PMS, 1000-1200 mg/d.
    • Hypercholesterolemia: (reduce LDL and raise HDL) with vitamin D, 1200 mg/d.

    Calcium (Ca)

    • Recommended daily intake: 1000-1500 mg, divided into 2-3 doses
    • Calcium Carbonate is the most highly concentrated form of calcium, (40% elemental calcium), requires more acidity to be effectively absorbed, so it should be taken with meals
    • Calcium citrate exhibits the best absorption, does not require extra stomach acid to dissolve
    • Calcium can interact with: Quinolones, Tetracyclines, Bisphosphonates, Digoxin, Diltiazem, Verapamil, Levothyroxine, Thiazide diuretics

    Zinc (Zn)

    • plays a vital role in numerous bodily functions, including:
      • vision maintenance (hepatic synthesis of Retinol binding protein that transports vitamin A)
      • immune function, supporting neutrophils, natural killer cells, and T lymphocytes
      • bone mineralization

    Benefits and Uses of Zinc

    • Reduces duration and severity of acute and persistent diarrhea
    • Treats acne (oral and topical)
    • Supplementation can aid in cases of Anorexia nervosa (50-100mg daily for six weeks to six months)
    • Increases sperm count ( 66-500mg of zinc sulfate daily for 13-26 weeks)
    • May contribute to alleviating depression symptoms ( 25 mg daily for 12 weeks in addition to antidepressant medication)

    Zinc Drug Interactions

    • Quinolones
    • Tetracyclines
    • Chromium
    • Digoxin
    • Coffee and dairy products

    Jamieson™ Zinc, 10 mg

    • Contains 10 mg Jamieson Zinc, equivalent to 77.6 mg of Zinc Gluconate, a highly absorbable form
    • Indications:
      • Hair loss
      • Rashes and skin lesions
      • Acne
      • Sterility and Impotence (20-50 mg)
      • Immune Stimulant (12 mg /day)
      • Appetizer (14 mg, for 2 months)

    Iron (Fe)

    • Stored as Ferritin
    • Found in:
      • Lean meats
      • Fish
      • Beans
      • Particularly high levels in beef, liver, and lamb

    Benefits and Uses of Iron

    • Treats iron deficiency anemia
    • Addresses Anemia of chronic disease (chronic renal failure & chemotherapy)
    • Manages Pregnancy-related iron deficiency anemia
    • Alleviates ACE inhibitor-associated cough (256 mg ferrous sulfate)
    • Combats fatigue (Ferrous sulfate 80 mg daily)

    Effects and Benefits of Iron

    • Key role in oxygen transport and metabolism (Hemoglobin)
    • A cofactor in the synthesis of neurotransmitters: Dopamine, norepinephrine, and serotonin
    • Enhances immune system function

    Iron Side Effects

    • May cause gastric upset, pain, constipation, diarrhea, nausea, and vomiting
    • High doses are unsafe. Iron is the most common cause of poisoning deaths in children

    Optimizing Iron Absorption

    • Vitamin C can increase iron absorption (200 mg vitamin C for each 30 mg iron)
    • Iron should be taken on an empty stomach if possible
      • Food can decrease absorption by 40% to 50%
      • However, if side effects are significant, it can be taken with food

    Iron Formulation Comparison

    • Polysaccharide-iron complex (Ferrose, Hemamax)
      • 100 % elemental iron
      • Ferric iron complexed to hydrolyzed starch, resulting in a tasteless and odorless product
      • Bioavailability similar to ferrous sulfate
      • Promoted for reduced GI irritation, but this claim lacks definitive proof
    • Carbonyl iron
      • 100 % elemental iron
      • Consists of microparticles of highly purified elemental iron; not an iron salt
      • Dissolves in gastric secretion and converts to hydrochloride salt before absorption in the stomach
      • Slow absorption rate, sustained iron release for 1 to 2 days
      • Less toxic than iron salts
    • Ferrous fumarate (Haemovit, Feroglobin)
      • 33 % elemental iron
      • Similar efficacy and tolerability to ferrous sulfate
      • Moderately soluble in water
      • Almost tasteless
      • Example: 325 mg tablet provides 108 mg of elemental iron
    • Ferrous sulfate (Ferro-fol, Feromin)
      • 20 % elemental iron
      • Preferred formulation for treating iron-deficiency anemia due to its general tolerability, effectiveness, and low cost
      • Example: 325 mg tablet contains 65 mg of elemental iron
    • Ferrous gluconate (Foliron)
      • 12 % elemental iron
      • Similar efficacy and tolerability to ferrous sulfate
      • Example: 325 mg tablet contains 35 mg of elemental iron

    Magnesium (Mg)

    • Vital role in regulating muscle contractility via calcium ion transport
    • Relaxes the muscle after calcium stimulates contraction

    Benefits and Uses of Magnesium

    • Supports healthy nerve and muscle function
    • Contributes to bone and teeth development and maintenance
    • Lowers blood pressure and reduces risk of osteoporosis
    • Supports muscle function and bone health

    Jamieson Magnesium 100 mg

    • Highly absorbable complex of five magnesium sources
    • Promotes strong bones and supports heart health and muscle function
    • For adults and adolescents (14 years and older): Take 1 tablet 2 times daily
    • Store between 15°C and 25°C

    Jamieson™ Magnesium, 100 mg

    • Indications
      • Relieves pains and muscle cramps (Low back pain, Back of calf pain & leg pain, Neck pain)

    Cross Selling Opportunities:

    • Skeletal Muscle relaxants (Relaxon, Parafon)
    • Muscle relaxant massage creams (Myolex cream , Chondroheel cream)

    Weight Gain

    • Eating more calories than you burn is required for weight gain.

    Underweight Individuals

    • May experience inhibited growth, especially in children and teens.
    • May have fragile bones and teeth.
    • May have a weak immune system, leading to frequent illnesses.
    • May experience anemia, a condition characterized by low red blood cell count.
    • May experience hair loss.
    • May experience fertility issues.

    Tips for Gaining Weight

    • Eat more frequently throughout the day to increase calorie intake.
    • Choose nutrient-rich foods that provide essential vitamins and minerals.
    • Try smoothies and shakes as convenient sources of calories and nutrients.
    • Mindful drinking as beverages may displace calorie-rich foods.
    • Maximize calorie intake by adding extras to meals, like nuts, cheese, or avocado.

    Dietary Supplements for Weight Gaining

    • Branched-chain amino acids (BCAAs) like valine, leucine, and isoleucine can help improve nutrition in older, undernourished individuals. Take 4 grams three times daily.
    • Zinc supplements might help with weight gain and improve depression symptoms in individuals with anorexia. Take 100mg of zinc gluconate daily.
    • Meal replacement shakes like Ensure Max and Serious Mass can be a convenient calorie source. Take 4 servings with 2 cups of water or milk.

    Biored Forte® Capsules

    • A natural supplement containing dried brewer's yeast and concentrated fenugreek extract.
    • Used for promoting appetite, improving digestion, and supporting stomach health.
    • Dried brewer's yeast helps stimulate appetite, improve digestion, support skin, hair, and nail health, regulate blood sugar levels and cholesterol, and treat anemia.
    • Concentrated fenugreek extract accelerates the conversion of carbohydrates to fats (lipogenesis) and promotes fat deposition in adipose tissues.

    Obesity Management Guidelines

    • Dietary Modifications: Aim for a 600 kcal daily energy deficit.
    • Physical Activity: Adults should engage in at least 30 minutes of moderate-intensity exercise five days a week. Preventing obesity may require 45-60 minutes of daily exercise, especially without calorie adjustments.
    • Behavioral Change: Address emotional eating, stress management, and social support.
    • Pharmacological Interventions: Consider medication for those with BMI ≥30 or ≥27 with comorbidities.
    • Surgery: Evaluate as an option for those with BMI ≥40 or ≥35 with comorbidities.

    Weight Management/Weight Reduction Medications

    • Centrally acting medications: Saxenda, Victoza (liraglutide), Ozempic (semaglutide), Mounjaro (tirzepatide) mimic GLP-1, a hormone that regulates appetite.

    • Peripherally acting medications: Xenical (orlistat) inhibits lipase, reducing fat absorption.

    Dietary Supplements for Weight Reduction

    • Supplements that impair dietary intake: Fibers like Extra Ananas.

    • Supplements that peripherally act to impair dietary absorption: Chitosan like applefit PLUS.

    • Supplements that increase energy expenditure: Chromium like Jamieson Chromium Chelate, Green Tea, and Caffeine.

    • Other supplements: Garcinia (hydroxy citric acid, HCA) plays a role in preventing fatty acid synthesis and lipogenesis after consuming a high-carbohydrate diet like Ysana SlimYsana and Garcimium. Jamieson CHROMIUM 200 MCG Chromium (HVP chelate) 200 mcg.

    Chromium Benefits

    • Helps maintain healthy blood sugar levels.
    • Decreases triglycerides and total cholesterol levels while increasing HDL (good) cholesterol levels.
    • Used for weight loss programs and obese patients.
    • Decreases appetite.
    • May help prevent diabetes.
    • Jamieson Chelated Chromium is formulated with vegetable protein for optimal absorption to support healthy glucose metabolism and help metabolize carbohydrates and fats.
    • Take 1 tablet daily with a meal.
    • May be helpful in managing obesity and increasing insulin sensitivity.

    Chromium Cross-selling Opportunities

    • Obesity-control medicines that don't contain Chromium. Ex: Xenical and Fatlos.
    • Pre-diabetic individuals (obese with a family history of diabetes).

    Women’s Health/Pregnancy and Lactation

    • Folic Acid: Helps prevent neural tube defects (NTDs) like spina bifida and anencephaly. May also reduce the risk of cleft lip and palate.
    • Iron: Prevents iron-deficiency anemia in the mother, which can lead to fatigue, weakness, and other health problems. Ensures the baby receives adequate iron for growth and development, especially important for premature and low-birth-weight infants.
    • Calcium and Vitamin D: Support bone health in both the mother and baby. Adequate intake is essential for preventing osteoporosis in the mother and ensuring strong bones in the baby.

    Dietary Supplements for Pregnancy and Lactation (Prenatal Vitamins)

    • Folic Acid: Take at least 400-600 mcg continued during the 1st month of pregnancy.
    • Vitamin C: Improves iron absorption.
    • Omega-3 Fish Oil: Take 2.7g of omega-3 fatty acids from week 18-30 pregnancy until delivery.
    • Pyridoxine (B6): For nausea and vomiting, take 25 mg every 8 hours for 72 to 96 hours.

    Women’s Health/Dysmenorrhea

    • Dysmenorrhea refers to painful menstrual cramps in the lower abdomen.
    • It is believed to be caused by an excess or imbalance of prostaglandins and leukotrienes, substances that cause uterine contractions.

    Dietary Supplements for Dysmenorrhea

    • Fish Oil Omega-3s: Take EPA 1080 mg and DHA 720 mg (2 gm fish oil).
    • Vitamin E: Take 200 IU twice daily starting 2 days before the menstrual period and continuing through the first 3 days of bleeding.
    • Vitamin B1 (Thiamine): Take 100 mg daily for 90 days to stop pain.

    Women’s Health/Premenstrual Syndrome (PMS)

    • Premenstrual Dysphoric Disorder (PMDD) is a severe form of premenstrual syndrome (PMS) causing significant emotional and physical symptoms in the days leading up to a woman's menstrual period.
    • These symptoms can interfere with daily life and relationships.

    Symptoms of PMDD

    • Emotional Symptoms: Depression, anxiety, irritability, anger, mood swings, crying spells.
    • Physical Symptoms: Fatigue, bloating, breast tenderness, abdominal pain, food cravings, headaches.

    Diagnosis of PMDD

    • Symptoms must be present in the five days before the period for at least three consecutive menstrual cycles.
    • Symptoms must end within four days after the period starts.
    • Symptoms must interfere with some of the woman's normal activities.

    Dietary Supplement s for PMS

    • Vitamin D + Calcium + Magnesium + Manganese: Significantly reduce depressed mood, water retention, and pain.
    • Vitamin E: Reduces anxiety, craving, and depression with a dose of 400 IU daily.
    • Brewer’s Yeast plus multivitamins.
    • Ginkgo Biloba: Take 80 mg twice daily, starting on the 16th day of the menstrual cycle until the 5th day of the next cycle.
    • Vitamin B6: Take 50-100 mg per day.
    • Royal Jelly with Bee pollen: Insufficient evidence to rate effectiveness.

    Jamieson Evening Primrose Oil

    • An essential natural source of Gamma linolenic acid (GLA) and Omega 6 fatty acids.
    • Used for relieving PMS symptoms like bloating, breast tenderness, abdominal cramps, irritability, and mood swings.
    • Used for treating eczema, diabetic neuropathy, and osteoporosis in combination with fish oil and calcium.

    Jamieson Evening Primrose Oil Benefits

    • Uses the purest and most potent evening primrose seeds grown in Canada.
    • Seeds are cold-pressed, and the oil is slowly extracted without chemical solvents for maximum potency.
    • Formulated to guarantee 10% GLA in each capsule (50 mg).
    • Contains Vitamin E to help prevent rancidity.

    Cross-Selling Opportunities for Primrose Oil

    • Topical corticosteroids and emollients for treating eczema.
    • PMS-symptom relieving medicines.

    Women’s Health/Menopause

    • Menopause is a natural process where women's ovaries stop producing estrogen, typically around age 51.
    • The years leading up to menopause, characterized by fluctuating hormone levels, are called perimenopause.

    Common Symptoms of Menopause

    • Hot flashes: Sudden sensations of heat and sweating.
    • Sleep problems: Insomnia, night sweats, and difficulty falling asleep.
    • Vaginal dryness: Can lead to discomfort during sex.
    • Increased urinary tract infections: Due to changes in the vaginal environment.

    Treatment Options for Menopause

    • Hormone therapy: Replacing lost estrogen can alleviate many menopausal symptoms.
    • Estrogen receptor modulators: Provide some benefits of estrogen without the same risks.
    • Antidepressants and anti-seizure medications: Help manage mood swings and hot flashes.
    • Local vaginal estrogen: Addresses vaginal dryness and discomfort.

    Dietary Supplements for Menopause

    • Soy: Helps reduce hot flushes. Take 50-120 mg/day of isoflavones.
    • St. John’s Wart: Might help improve hot flushes. Take 300 mg once daily.
    • Evening Primrose: Used in combination with fish oil and calcium for treating age-related osteoporosis.

    Women’s Health/Hair and Skin Health

    Supplements for Hair Loss

    • Vitamin B5 (Pantothenic acid).
    • Vitamin B7 (Biotin) in combination with Zinc.

    Cystine B6® Tablets

    • Ingredients: Cysteine, Zinc, Vitamin B6, Arginine.
    • Indications: Hair loss, hair density, shiny hair, nail health.
    • Dosage: 2 tablets/twice daily for 3 months.

    Cystine B6® Benefits

    • Cysteine: Transports essential minerals (iron and zinc) for hair regrowth, strengthens hair, prevents waves and curls, protects hair from damage, decreases frizz, and adds shine without increasing body weight.
    • Zinc: Deficiency can cause changes in the hair follicle protein structure, weakening their structural integrity, leading to faster hair loss.
    • Vitamin B6: Binds to testosterone receptors and stops DHT formation.
    • Arginine: Supports blood flow and hair growth.

    Supplements for Wrinkles and Whitening

    • **Glutathione ** (Gluta500 Tab, Gluta Maxx).
    • **Pycnogenol ** for 3 months (Pycnox tab).

    Acne Supplement

    • Zinc (oral and topical): Take orally with doses of 30-130 mg elemental zinc daily (10 mg Jamieson Zinc (elemental) = 77.6 mg of Zinc Gluconate).
    • Co-enzyme Q10: Take 60 mg twice daily.
    • Vitamin C: Take 500 mg daily in addition to regular antihypertensive drugs.

    Dietary Supplements for Hypertension

    • Garlic: Decreases blood pressure, systolic by 16 mmHg and diastolic by 9 mmHg. Take 600-1200 mg daily divided into 3 doses.
    • Fish Oil: Reduces systolic blood pressure by 3.4-5.5 mmHg and diastolic blood pressure by 2.0-3.5 mmHg. Take 2-4g of omega-3 fatty acids daily for up to a year.
    • Cod Liver Oil: Take 20 ml daily (contains 1.8 grams EPA, 2.2 grams DHA, 15,000 IU vitamin A, and 1500 IU vitamin D).
    • Co-enzyme Q10: Take 120-200 mg per day divided into 2 doses.
    • Calcium: Take 1000 – 1500 mg daily.
    • Hibiscus: Drink 240mL tea containing 1.25-2g of Hibiscus Calyx (6-30 minutes in boiling water) 1-3 times daily for 4-6 weeks.

    Dietary Supplements for Hypercholesterolemia

    • Green Tea: Take 3-10 cups OR 1-3 capsules daily.

    • Possibly Effective:*

    • Calcium Carbonate: Take 400 mg three times daily to reduce LDL cholesterol by 4.4% and increase HDL by 4.1% after 6 weeks.

    • Magnesium: Combine with calcium (1200 mg) and vitamin D (400 IU) to reduce the total cholesterol: HDL ratio and LDL: HDL ratio. Supports patients suffering from Statin-induced myalgia.

    • Chromium: Take 15-200 mcg daily for 6-12 weeks to decrease LDL cholesterol and total cholesterol.

    • Artichoke: Modestly reduces total and LDL cholesterol, and the LDL/HDL ratio over 6 to 12 weeks of treatment.

    • Insufficient Evidence to Rate:*

    • Royal Jelly: Take 30-150 mg for 4-6 weeks.

    • Vitamin C: Take 500 mg daily for at least 4 weeks to reduce LDL cholesterol by 7.9 mg/dL and triglycerides by 20.1 mg/dL.

    • Brewer’s yeast: Take 5-30g of brewer's yeast containing 23-50mcg of chromium for 8-12 weeks may decrease the levels of total cholesterol and can increase levels of high density lipoprotein (HDL)-cholesterol.

    • Black seed.

    For Statin-induced Myopathy

    • Coenzyme Q10: Take 100-200 mg daily for 3 months.
    • Calcium plus vitamin D.

    Coenzyme Q10 (Co Q10) Uses

    • Diabetic neuropathy: Take 400mg daily for 12 weeks.
    • Hypertension: Take 100 to 120 mg daily.
    • Prevent migraine headache : Take 100 mg TID for 3 months.
    • **Male infertility :**Take 200 to 300 mg daily for 6 months.
    • Improve Fibromyalgia.
    • Reduce pre-eclampsia.

    Dietary Supplements for Hypertriglyceridemia

    • Effective:*

    • Fish Oil: Decreases secretion of VLDL, increases VLDL apolipoprotein B secretion, increasing VLDL clearance, decreasing VLDL size, and reducing triglyceride transport. The effect is dose-dependent, with higher doses having greater effects. Take 2-4 gm of omega-3 fatty acids daily for 12-24 weeks.

    • Likely Effective:*

    • Green Tea.

    • Cod Liver Oil.

    • Insufficient Reliable Evidence to Rate:*

    • Vitamin B12.

    Dietary supplements for Male Infertility

    • Vitamin E: Improves sperm quality and motility.
    • L-Carnitine: Boosts sperm count and movement.
    • Acetyl L-carnitine: Enhances sperm quality, especially when combined with L-carnitine.
    • CoQ10: Improves sperm motility and density.
    • Zinc: Increases sperm count when combined with other antioxidants.
    • Horse Chestnut: Increase sperm density in men with varicocele- associated infertility, it may not improve sperm motility.

    Vitamin E (Alpha-tocopherol)

    • The most active form in humans
    • Found in eggs, fortified cereals, fruit, green leafy vegetables (such as spinach), meat, etc.
    • Anti-oxidant effect
    • Cardioprotective: inhibiting oxidation of (LDL) cholesterol and through the inhibition of platelet aggregation
    • Enhance immune system
    • Drug Drug interaction:* Anticoagulant/Antiplatelet drugs, e.g.aspirin, clopidogrel, dalteparin, enoxaparin, heparin and warfarin (added bleeding effect)

    Vitamin E Uses

    • Dementia (with Vit C ) dose 800 – 2000 IU/day
    • Alzheimer’s disease
    • Dysmenorrhea (dose 200 IU twice daily or 500 IU starting 2 days before menstruation and continuing through the first 3 days of bleeding)
    • Premenstrual syndrome (PMS)
    • Physical performance and muscle strength in elderly patient
    • Rheumatoid arthritis (reduce pain but not inflammation )
    • Infertility (asthenospermia or oligoasthenospermia with dose 200 – 600 IU daily)

    Dietary supplements for Erectile dysfunction:

    • Panax Ginseng: Improves blood flow and erectile function.
    • L-Arginine: Supports blood flow and nitric oxide production, essential for erections.
    • *( L-Arginine Drug interactions: 1.Avoid With Nitrates, PDE 5 inhibitors (Viagra, Cialis, Levitra), Anti-hypertensive drugs) 2.Avoid in recent heart attack, kidney malfunction, Herpes infection, and Surgery)
    • Yohimbine: May improve erectile function in some cases but should be used with caution and under medical supervision due to potential side effects and interactions with other medications. (Yohimbine Drug interactions: 1.Avoid With Tricyclic antidepressant, antihypertensives, pseudoephedrine) 2.Avoid in recent Bleeding disorders, prostate, psychological problems e.g.anxiety, depression)

    Medications used for BPH

    • Alpha blockers: e.g., Cardura, Xatra
    • Phosphodiesterase-5 inhibitors Tadalafil may relax smooth muscles in the lower urinary tract in addition to ED treatment.
    • 5-alpha reductase inhibitors: e.g., Finasteride and Dutasteride

    Dietary supplements for BPH

    • Pumpkin Seeds: Rich in phytosterols, pumpkin seeds may help reduce prostate inflammation and improve urinary flow.
    • Saw Palmetto: This herbal extract has been traditionally used to treat BPH symptoms. It may help reduce prostate size and improve urinary function.
    • Garlic: Some studies suggest garlic may be beneficial for BPH symptoms, but more research is needed to confirm its effectiveness.

    Vitamin D Levels (25-hydroxyvitamin D)

    • Deficient: <250 nmol/L).

    Vitamin D Doses

    • Vitamin D deficient patients: 50,000 IU once weekly for 8 weeks then 1000 IU/d daily for maintenance.
    • Vitamin D inadequate patients: 5000 IU/d daily for 4-6 weeks then 1000 IU/d daily for maintenance.
    • Vitamin D adequate: 1000 IU/d for maintenance.

    Fat-Soluble Vitamins / Vitamin D

    • Regulates calcium and phosphorus absorption in the intestines.
    • Helps maintain strong bones and teeth.
    • Supports immune function.
    • Vitamin D drug drug interactions:
      • Aluminum (Antacids): Take vitamin D 2 hrs before, or 4 hours after antacids (may increase Al absorption).
      • Digoxin (Lanoxin): May cause fatal cardiac arrhythmia in case of high doses.
      • Diltiazem.Verapamil.
      • Thiazide diuretics: cause hypercalcemia.

    Vitamin D required Daily Intake

    • Generally recommended daily intake for adults: 400-800 International Units (IUs).

    High Dose Vit D Side Effects

    • Hypercalcemia (excess calcium in the blood).
    • Kidney stones.
    • Nausea.
    • ** Vomiting**.
    • Weakness.

    Jamieson™ D3 Tab

    • Formulated with Quali®-D, the world’s premium, natural vitamin D3.
    • Fully sustainable and traceable from farm to finish.
    • Manufactured using 360 pure process.

    Jamieson™ D3 Tab Indications

    • Essential for normal development and maintenance of bones and teeth.
    • Helps in the absorption and use of calcium and phosphorus in the body.
    • Helps prevent vitamin D deficiency.

    Vitamin E

    • Vit E (Alpha-tocopherol): is the most active form in humans. Found in eggs, fortified cereals, fruit, green leafy vegetables (such as spinach), meat, etc.

    Vitamin E Uses

    1. Dementia (with Vitamin C): 800-2000 IU/d
    2. Alzheimer's disease
    3. Dysmenorrhea: reduce menstrual pain severity and duration and decrease blood loss (200 IU twice daily or 500 IU daily starting 2 days before menstruation and continuing through the first 3 days of bleeding)
    4. Premenstrual syndrome (PMS)
    5. Physical performance and muscle strength in elderly people
    6. Rheumatoid arthritis: reduce pain but not inflammation
    7. Infertility (asthenospermia or oligoasthenospermia): 200-600 IU daily
    8. Antioxidant effect (Cardioprotective effect): Inhibiting oxidation of (LDL) cholesterol and Through the inhibition of platelet aggregation
    9. Enhance immune system

    Vitamin E drug drug interactions

    1. Anticoagulant/Antiplatelet: Drugs, e.g.aspirin, clopidogrel, dalteparin, enoxaparin, heparin, and warfarin Increased bleeding effect

    Vitamin E Effect

    • Antioxidant effect.
    • Cardioprotective: inhibiting oxidation of (LDL) cholesterol and through the inhibition of platelet aggregation.
    • Enhance immune system.

    Calcium (Ca)

    • Essential part of bones and teeth.
    • The heart, nerves, and blood-clotting systems also need calcium to work.
    • Found in eggs, fortified cereals, fruit, green leafy vegetables (such as spinach), meat, etc.

    Uses of Calcium

    1. Dyspepsia (Antacids: Carbonate)
    2. Hypocalcemia
    3. Increases fetal bone mineralization and density (during pregnancy)
    4. Fall prevention in older people (Ca+Vit D)
    5. Premenstrual Syndrome (PMS): significantly reduce depressed mood, water retention, and pain associated with PMS, 1000-1200 mg/d
    6. Hypercholesterolemia: (reduce LDL and raise HDL) with vitamin D, 1200 mg/d

    Jamieson Kids Multi Chewable

    • Contains iron, to promote healthy growth and development
    • Formulated with no artificial colours or flavours
    • Contains 12 vitamins and 6 minerals
    • Provides essential vitamins and minerals for normal growth and development (Vitamin A, C, D, B complex, Iron & Zinc)
    • Helps prevent iron deficiency.

    Jamieson Adults Multi Chewable

    • Provides 100% of the body's daily vitamin needs
    • Contains 14 vitamins and 8 minerals
    • Provides Lutein & Choline
    • Citrus Twist flavor
    • Formulated to Health Canada's recommendations

    Herbal supplements/ Ginkgo Biloba

    • Has antioxidant and free radical scavenging properties
    • Competitively inhibits platelet-activating factor (PAF)
    • Improves blood flow to capillaries throughout the body
    • Inhibits toxicity and cell death induced by beta-amyloid peptides in Alzheimer patients
    • Improves memory and speed of cognitive processing
    • Effective for Vertigo and equilibrium disorders
    • Aids in Premenstrual syndrome (PMS) relief
    • Improves Fibromyalgia symptoms (physical fitness levels, emotional feelings, social activities, overall health, and pain)

    Drug Drug Interactions: Ginkgo Biloba

    • Bleeding risk if taken with anticoagulant/antiplatelet drugs (aspirin, clopidogrel, dalteparin, enoxaparin, heparin, and warfarin).
    • Bleeding risk if taken with other herbs that may cause bleeding (G.G.Corns, Ginger, Garlic, Clove)

    Herbal supplements/ Ginseng

    • Aids in Erectile dysfunction
    • Increases insulin sensitivity with diabetic patients
    • Enhances Memory
    • Enhances Appetite

    Drug Drug Interactions: Ginseng

    • Bleeding risk if taken with anticoagulant/antiplatelet drugs (aspirin, clopidogrel, dalteparin, enoxaparin, heparin and warfarin)

    Omega 3 Supplements

    • Contraindications: Seafood Allergy, anti-coagulant anti-platelet drugs (DISPRIN 81, ASPIRIN PROTECT 100, Plavix), elevated triglyceride levels (> 500)

    Omega 3 Doses

    • Adult: Less than 3 gm daily
    • Children: 1/3 to 1/2 of adult dose

    Benefits and Uses of Omega-3:

    • Improves dry eye symptoms
    • Improves dry skin (Atopic Dermatitis)
    • Aids in pregnancy and fetus brain development
    • Improves depression and works with anti-depressant medications (SSRI)
    • Helps with hypertriglyceridemia and hypercholesterolemia
    • Reduces inflammation (Arthritis)
    • Reduces inflammation (Asthma)
    • Reduces inflammation (Dysmenorrhea)

    Major Minerals/Zinc (ZN)

    • Plays a key role in the maintenance of vision
    • Important for immune system function
    • Involved in the mineralization of bone

    Uses of Zinc

    • Reduces the duration and severity of diarrhea.
    • Treats acne
    • Treats anorexia nervosa
    • Increases sperm count in infertile men
    • Works in conjunction with anti-depressant drugs
    • Enhances the immune system

    Cross-selling Opportunities: Zinc

    • PDE5 inhibitors/Sexual tonics: Improves synthesis of Testosterone
    • Hair Loss Topical preparations + Priorin tablets
    • Appetite Stimulant
    • Acne treatment

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    Description

    Explore the unique qualities of Manuka honey, derived from the Manuka tree in New Zealand. This quiz delves into its potential health benefits, the importance of UMF and MGO in measuring potency, and its various uses in topical and oral applications. Test your knowledge about this remarkable natural product!

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