Management of Diabetic Complications: Acute Complications Lecture
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Questions and Answers

What is the primary goal of achieving good glycemic control in diabetes mellitus?

  • Reducing the risk of long-term complications only
  • Reducing the risk of short-term complications only
  • Reducing the risk of tissue damage only
  • Reducing the risk of both short- and long-term complications (correct)

What symptoms are commonly associated with hypoglycemia in diabetic patients?

  • Blurred vision and slow wound healing
  • Vomiting, abdominal pain, and rapid breathing
  • Dizziness, confusion, and sweating (correct)
  • Excessive urination, fatigue, and weight loss

What differentiates diabetic ketoacidosis (DKA) from hyperosmolar hyperglycemic state (HHS)?

  • DKA is associated with low blood sugar levels, while HHS is associated with high blood sugar levels
  • DKA is more common in type 1 diabetes, while HHS is more common in type 2 diabetes (correct)
  • DKA and HHS are the same condition with different names
  • DKA is associated with high blood sugar levels, while HHS is not

Which complication is diabetes the leading cause of?

<p>Kidney failure (D)</p> Signup and view all the answers

What other complications can diabetes mellitus contribute to?

<p>All of the above (D)</p> Signup and view all the answers

What is the initial management for diabetic ketoacidosis (DKA)?

<p>Restoration of circulatory volume and tissue perfusion (B)</p> Signup and view all the answers

What are the common clinical signs of diabetic ketoacidosis (DKA)?

<p>Hyperventilation and Kussmaul respirations (B)</p> Signup and view all the answers

What is the main goal of therapy for diabetic ketoacidosis (DKA)?

<p>Replacing the fluid deficit (B)</p> Signup and view all the answers

What is the primary treatment for hyperglycemia in individuals with diabetes?

<p>Insulin therapy (D)</p> Signup and view all the answers

What should be evaluated in individuals with diabetes >40 years of age, according to the DCCT-EDIC study published in NEJM 2005?

<p>Atherosclerotic cardiovascular disease (ASCVD) risk (C)</p> Signup and view all the answers

What is the primary goal of managing hypertension in individuals with diabetes?

<p>Achieving a blood pressure goal of 10/&lt;12/&lt;12 (C)</p> Signup and view all the answers

What are the two major types of vascular and tissue damage that can occur as long-term complications of diabetes?

<p>Microvascular and macrovascular damage (D)</p> Signup and view all the answers

Which of the following is not a common symptom of elevated blood sugar in individuals with diabetes?

<p>Weight gain (D)</p> Signup and view all the answers

Which of the following is not a risk factor for developing complications from diabetes?

<p>Exercise (B)</p> Signup and view all the answers

Which of the following best describes the primary goal of managing hypertension in individuals with diabetes?

<p>To prevent or delay the progression of diabetic nephropathy (B)</p> Signup and view all the answers

Which of the following is the most common cause of nontraumatic limb amputations?

<p>Diabetic foot ulcers (D)</p> Signup and view all the answers

Which of the following is the most common cause of blindness in individuals with diabetes?

<p>Diabetic retinopathy (A)</p> Signup and view all the answers

What is the primary treatment for hyperglycemia in individuals with diabetic ketoacidosis (DKA), according to the Diabetes Care 2009 Jul; 32(7): 1335-1343 article?

<p>Fluid replacement, insulin therapy, and electrolyte correction (B)</p> Signup and view all the answers

According to the DCCT-EDIC study published in NEJM 2005, what is the recommended statin intensity for individuals with diabetes mellitus who are at higher risk for atherosclerotic cardiovascular disease (ASCVD)?

<p>High-intensity statin (A)</p> Signup and view all the answers

Which clinical sign is not typically associated with diabetic ketoacidosis (DKA), according to the Diabetes Care 2009 Jul; 32(7): 1335-1343 article?

<p>Bradycardia (B)</p> Signup and view all the answers

What is the main goal of therapy for diabetic ketoacidosis (DKA), according to the Diabetes Care 2009 Jul; 32(7): 1335-1343 article?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary goal of managing hypertension in individuals with diabetes, according to the DCCT-EDIC study published in NEJM 2005?

<p>Preventing cardiovascular disease (A)</p> Signup and view all the answers

What is the main complication that diabetes mellitus is the leading cause of, according to the DCCT-EDIC study published in NEJM 2005?

<p>Heart disease (D)</p> Signup and view all the answers

What is the formula for calculating the effective serum osmolality as mentioned in the text?

<p>2 × (measured Na+ level) + glucose level/18 (C)</p> Signup and view all the answers

In diabetic ketoacidosis (DKA), what is the primary goal of correcting electrolyte imbalances, specifically focusing on potassium?

<p>Correct hypokalemia (D)</p> Signup and view all the answers

How are Kussmaul respirations typically characterized in individuals with DKA?

<p>Hyperventilation with deep, labored breathing (C)</p> Signup and view all the answers

In the context of diabetic ketoacidosis, why is it essential to simultaneously manage circulatory volume and tissue perfusion?

<p>To restore normal blood glucose levels (B)</p> Signup and view all the answers

What is the main significance of assessing CVD risk using ASCVD calculator in individuals with diabetes?

<p>To guide statin therapy intensity (D)</p> Signup and view all the answers

Why is it essential for individuals with diabetes over 40 years of age to be on a moderate to high-intensity statin?

<p>To reduce ASCVD risk (A)</p> Signup and view all the answers

Which of the following is a common symptom of both hypoglycemia and hyperglycemia in individuals with diabetes?

<p>Excessive urination (A)</p> Signup and view all the answers

Which of the following complications is diabetes NOT the leading cause of?

<p>Periodontal disease (A)</p> Signup and view all the answers

Which of the following is a common complication of both microvascular and macrovascular damage in individuals with diabetes?

<p>Skin and soft tissue infections (B)</p> Signup and view all the answers

Which of the following is NOT a recommended treatment for managing diabetic ketoacidosis (DKA)?

<p>Metformin therapy (D)</p> Signup and view all the answers

Which of the following is NOT a risk factor for developing complications from diabetes?

<p>Exercise (C)</p> Signup and view all the answers

Which of the following is a common symptom of hyperosmolar hyperglycemic state (HHS), but NOT diabetic ketoacidosis (DKA)?

<p>Confusion and lethargy (B)</p> Signup and view all the answers

Elevated blood sugar can lead to hypoglycemia.

<p>False (B)</p> Signup and view all the answers

Hypoglycemia can lead to seizure and death.

<p>True (A)</p> Signup and view all the answers

Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are acute complications of diabetes.

<p>True (A)</p> Signup and view all the answers

Long-term complications of diabetes include vascular and tissue damage.

<p>True (A)</p> Signup and view all the answers

Diabetes is not a leading cause of blindness.

<p>False (B)</p> Signup and view all the answers

Individuals with diabetes do not have an increased risk of skin and soft tissue infections.

<p>False (B)</p> Signup and view all the answers

Individuals with diabetes over 40 years of age should not be on any statin medication.

<p>False (B)</p> Signup and view all the answers

Cessation of ketogenesis is a step in the initial management of diabetic ketoacidosis.

<p>True (A)</p> Signup and view all the answers

Changes in mental status are not a sign of diabetic ketoacidosis.

<p>False (B)</p> Signup and view all the answers

The formula for calculating effective serum osmolality includes serum glucose content.

<p>True (A)</p> Signup and view all the answers

The primary goal of therapy for diabetic ketoacidosis is to replace fluid deficit.

<p>True (A)</p> Signup and view all the answers

In diabetic ketoacidosis, correcting electrolyte imbalances does not involve managing potassium levels.

<p>False (B)</p> Signup and view all the answers

Hypoglycemia can lead to seizures and death.

<p>True (A)</p> Signup and view all the answers

In diabetic patients, elevated blood sugar can lead to skin and soft tissue infections.

<p>False (B)</p> Signup and view all the answers

Controlling blood sugar helps reduce the risk of both short- and long-term complications in type 1 and type 2 diabetes.

<p>True (A)</p> Signup and view all the answers

Diabetes is not a leading cause of blindness.

<p>False (B)</p> Signup and view all the answers

Vascular and tissue damage are considered long-term complications of diabetes.

<p>True (A)</p> Signup and view all the answers

Hypertension management is not a key aspect of managing diabetes.

<p>False (B)</p> Signup and view all the answers

Individuals with diabetes over 40 years of age should be on high-intensity statin therapy according to the DCCT-EDIC study.

<p>False (B)</p> Signup and view all the answers

One of the common clinical signs of diabetic ketoacidosis (DKA) is acetone breath.

<p>True (A)</p> Signup and view all the answers

Cessation of ketogenesis is a step in the initial management of hyperglycemia.

<p>False (B)</p> Signup and view all the answers

The primary goal of managing diabetic ketoacidosis (DKA) is to correct electrolyte imbalances.

<p>False (B)</p> Signup and view all the answers

Individuals with diabetes between 30-40 years of age should minimally be on a low to moderate intensity statin according to the DCCT-EDIC study.

<p>True (A)</p> Signup and view all the answers

Kussmaul respirations are characterized by shallow, rapid breathing patterns in individuals with diabetic ketoacidosis (DKA).

<p>False (B)</p> Signup and view all the answers

Controlling blood sugar helps reduce the risk of both short- and long-term complications in type 1 and type 2 diabetes.

<p>True (A)</p> Signup and view all the answers

Elevated blood sugar can lead to hypoglycemia.

<p>False (B)</p> Signup and view all the answers

Vascular and tissue damage are considered short-term complications of diabetes.

<p>False (B)</p> Signup and view all the answers

Kussmaul respirations are characterized by deep, slow breathing patterns in individuals with diabetic ketoacidosis (DKA).

<p>False (B)</p> Signup and view all the answers

Diabetes is the leading cause of nontraumatic limb amputations.

<p>True (A)</p> Signup and view all the answers

In diabetic ketoacidosis (DKA), correcting electrolyte imbalances does not involve managing potassium levels.

<p>False (B)</p> Signup and view all the answers

Individuals with diabetes over 40 years of age should minimally be on a moderate intensity statin according to the DCCT-EDIC study.

<p>False (B)</p> Signup and view all the answers

Kussmaul respirations are labored breathing patterns in individuals with diabetic ketoacidosis (DKA).

<p>False (B)</p> Signup and view all the answers

The primary goal of therapy for diabetic ketoacidosis is to restore circulatory volume and tissue perfusion.

<p>False (B)</p> Signup and view all the answers

Changes in mental status are common signs of dehydration in individuals with diabetic ketoacidosis.

<p>True (A)</p> Signup and view all the answers

Acetone breath is a usual sign of hyperglycemia in individuals with diabetes.

<p>True (A)</p> Signup and view all the answers

The formula for calculating the effective serum osmolality involves 2 times the measured sodium plus glucose divided by 18.

<p>True (A)</p> Signup and view all the answers

What is the primary goal of managing circulatory volume and tissue perfusion simultaneously in the context of diabetic ketoacidosis (DKA)?

<p>To rapidly restore fluid deficit (A)</p> Signup and view all the answers

Which of the following statements best describes the role of statins in individuals with diabetes over 40 years of age, according to the DCCT-EDIC study?

<p>Individuals with diabetes should minimally be on a moderate-intensity statin (A)</p> Signup and view all the answers

Which of the following is NOT a key aspect of managing hypertension in individuals with diabetes, as mentioned in the text?

<p>Variable mental status assessment (C)</p> Signup and view all the answers

Which of the following is NOT a common clinical sign of diabetic ketoacidosis (DKA)?

<p>Hypertension (C)</p> Signup and view all the answers

Which of the following is the primary goal of correcting electrolyte imbalances, specifically focusing on potassium, in individuals with diabetic ketoacidosis (DKA)?

<p>To prevent the progression of electrolyte imbalances (C)</p> Signup and view all the answers

Which of the following is NOT a step in the initial management of diabetic ketoacidosis (DKA)?

<p>Administration of diuretics to manage fluid overload (B)</p> Signup and view all the answers

Which of the following is the most accurate differentiator between DKA and HHS?

<p>HHS is more commonly associated with changes in mental status than DKA. (A)</p> Signup and view all the answers

Which of the following is the primary goal of managing hypertension in individuals with diabetes?

<p>Reducing the risk of atherosclerotic cardiovascular disease (B)</p> Signup and view all the answers

Which of the following is the main goal of therapy for diabetic ketoacidosis (DKA)?

<p>Restoring circulatory volume and tissue perfusion (B)</p> Signup and view all the answers

Which of the following long-term complications of diabetes is not primarily associated with vascular and tissue damage?

<p>Periodontal disease (A)</p> Signup and view all the answers

Which of the following is the most accurate statement about the DCCT-EDIC and UKPDS studies?

<p>The UKPDS found that intensive glycemic control in type 2 diabetes reduces both microvascular and macrovascular complications. (C)</p> Signup and view all the answers

Which of the following is NOT an approach to managing and preventing hypoglycemia?

<p>Initiating insulin therapy in non-insulin dependent diabetes (C)</p> Signup and view all the answers

What is the primary goal of managing hypertension in individuals with diabetes, as stated in the text?

<p>To reduce the risk of heart disease (A)</p> Signup and view all the answers

Why is it important for individuals with diabetes over 40 years of age to be on a moderate to high-intensity statin?

<p>To decrease the risk of heart disease (C)</p> Signup and view all the answers

Which nontraumatic condition is diabetes NOT the leading cause of?

<p>Erectile dysfunction (C)</p> Signup and view all the answers

What symptom is commonly associated with hyperosmolar hyperglycemic state (HHS) but NOT with diabetic ketoacidosis (DKA)?

<p>Profound dehydration (C)</p> Signup and view all the answers

Which is NOT a significant step in managing acute complications of diabetes?

<p>Preventing skin infections (B)</p> Signup and view all the answers

What is a key aspect in achieving good glycemic control to prevent acute complications in diabetes?

<p>Avoiding hypoglycemia (A)</p> Signup and view all the answers

What is the primary goal of managing hypertension in individuals with diabetes?

<p>To prevent both microvascular and macrovascular complications (C)</p> Signup and view all the answers

What is the typical mental status of a patient with diabetic ketoacidosis (DKA)?

<p>Stupor/coma (A)</p> Signup and view all the answers

Which of the following symptoms is NOT a usual sign of hyperglycemia in diabetic patients?

<p>Night sweats (D)</p> Signup and view all the answers

How is the effective serum osmolality calculated?

<p>2[measured Na+ (mEq/L)] + glucose (mg/dL)/18 (C)</p> Signup and view all the answers

What is the main goal of therapy for diabetic ketoacidosis (DKA)?

<p>To close the anion gap (A)</p> Signup and view all the answers

Which of the following is NOT a step in the initial management of diabetic ketoacidosis (DKA)?

<p>Resolution of hypoglycemia (C)</p> Signup and view all the answers

What is the recommended blood pressure goal for individuals with diabetes?

<p>130/80 mmHg (A)</p> Signup and view all the answers

What is the primary goal of managing hypertension in individuals with diabetes?

<p>To improve cardiovascular health (A)</p> Signup and view all the answers

Which is the preferred initial fluid for individuals with diabetic ketoacidosis (DKA)?

<p>0.9% normal saline (B)</p> Signup and view all the answers

Which is NOT a common clinical sign of diabetic ketoacidosis (DKA)?

<p>Hypotension (D)</p> Signup and view all the answers

Which of the following is NOT a risk factor for atherosclerotic cardiovascular disease (ASCVD) in individuals with diabetes?

<p>Age between 40 and 60 years (D)</p> Signup and view all the answers

Which of the following is the primary goal of good glycemic control in individuals with diabetes?

<p>To reduce the risk of long-term complications (A)</p> Signup and view all the answers

What are the short-term complications of poorly managed diabetes mellitus?

<p>Elevated blood sugar leading to excessive urination, fatigue, weight loss, and DKA or HHS (A)</p> Signup and view all the answers

Which of the following is a common complication of both microvascular and macrovascular damage in individuals with diabetes?

<p>Blindness (B)</p> Signup and view all the answers

What are the major complications of diabetes, according to the text?

<p>Increased risk of heart disease, blindness, limb amputations, and kidney failure (A)</p> Signup and view all the answers

What is the main significance of assessing CVD risk using the ASCVD calculator in individuals with diabetes?

<p>To identify those at higher risk for atherosclerotic cardiovascular disease (ASCVD) (B)</p> Signup and view all the answers

What is the main difference between diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS)?

<p>DKA is characterized by a high anion gap metabolic acidosis, while HHS is characterized by hyperosmolality and severe dehydration (A)</p> Signup and view all the answers

Which of the following is NOT a long-term complication of diabetes?

<p>Liver failure (C)</p> Signup and view all the answers

What is the primary goal of managing hypertension in individuals with diabetes, according to the DCCT-EDIC study?

<p>To reduce the risk of atherosclerotic cardiovascular disease (ASCVD) (D)</p> Signup and view all the answers

What is the primary treatment for hyperglycemia in individuals with diabetic ketoacidosis (DKA)?

<p>Insulin therapy (B)</p> Signup and view all the answers

Which of the following is NOT a common clinical sign of diabetic ketoacidosis (DKA)?

<p>Fever (B)</p> Signup and view all the answers

What is the recommended blood pressure goal for individuals with diabetes, according to the DCCT-EDIC study?

<p>130/80 mmHg (A)</p> Signup and view all the answers

What is the main difference between diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS)?

<p>DKA is characterized by ketosis, while HHS is not (B)</p> Signup and view all the answers

What is the main significance of assessing CVD risk using ASCVD calculator in individuals with diabetes?

<p>To determine the appropriate statin intensity (C)</p> Signup and view all the answers

What is the primary goal of achieving good glycemic control in diabetes mellitus?

<p>To reduce the risk of both short- and long-term complications (D)</p> Signup and view all the answers

Which of the following is a major complication of diabetes that is NOT directly associated with vascular and tissue damage?

<p>Periodontal disease (D)</p> Signup and view all the answers

Why is controlling blood sugar essential in individuals with diabetes over 40 years of age?

<p>To reduce the risk of heart disease and blindness (D)</p> Signup and view all the answers

What is the main difference between diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS)?

<p>Underlying causes of the conditions (D)</p> Signup and view all the answers

Which of the following represents a short-term complication of diabetes?

<p>Excessive urination and weight loss (A)</p> Signup and view all the answers

What is considered a primary approach to managing and preventing hypoglycemia?

<p>Regularly monitoring blood glucose levels (B)</p> Signup and view all the answers

Flashcards

Glycemic control goal

Reducing the risk of short- and long-term diabetes complications.

Hypoglycemia symptoms

Dizziness, confusion, and sweating.

DKA vs. HHS

DKA (type 1) vs. HHS (type 2) - differing types of diabetes.

Diabetes leading cause

Kidney failure is the primary complication of diabetes.

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DKA initial management

Restoring circulatory volume and tissue perfusion.

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DKA clinical signs

Hyperventilation and Kussmaul respirations.

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DKA therapy goal

Replacing the fluid deficit in the body.

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Hyperglycemia treatment

Insulin therapy.

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Diabetes >40 ASCVD risk

Evaluating atherosclerotic cardiovascular disease risk.

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Hypertension in diabetes goal

Achieve a blood pressure goal of 10/<12/<12.

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Vascular damage types

Microvascular and macrovascular damage.

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Non-symptom of elevated blood sugar

Weight gain.

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Non-risk factor for diabetes complications

Exercise.

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Hypertension management goal (diabetes)

Preventing or slowing down diabetic nephropathy.

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Nontraumatic limb amputation cause

Diabetic foot ulcers.

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Diabetes blindness cause

Diabetic retinopathy.

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DKA primary treatment (Diabetes Care 2009)

Fluid replacement, insulin, and electrolyte correction.

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High-risk diabetes statin intensity

High-intensity statin.

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Non-DKA clinical sign (Diabetes Care 2009)

Bradycardia (slow heart rate).

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DKA therapy goal (Diabetes Care 2009)

Correcting fluid loss, electrolyte imbalances, and high blood sugar.

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Diabetes hypertension management goal (DCCT-EDIC)

Preventing cardiovascular disease.

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Diabetes leading complication (DCCT-EDIC)

Heart disease.

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Effective serum osmolality formula

2 × (measured Na+) + (glucose/18).

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DKA potassium correction goal

Correct hypokalemia.

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Kussmaul respirations in DKA

Hyperventilation with deep, labored breathing.

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Simultaneous volume/perfusion DKA goal

Restoring normal blood glucose levels and blood flow.

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