Inflammatory Bowel Disease Risk Factors and Genetic Factors Quiz
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Questions and Answers

What is the concordance rate among monozygotic twins for Crohn's Disease (CD) compared to Ulcerative Colitis (UC)?

  • 30% for CD and 50% for UC
  • 50% for CD and 30% for UC
  • 70% for CD and 20% for UC (correct)
  • 20% for CD and 70% for UC

    • Which gene is abnormal in Inflammatory Bowel Disease (IBD) and functions as an intracellular sensor of bacteria?

  • NOD2/CARD15 gene (correct)
  • TP53 gene
  • CFTR gene
  • BRCA1 gene

    • What is a common clinical presentation of Crohn’s Disease?

  • Back pain
  • Epigastric pain
  • Left upper quadrant pain
  • Right lower quadrant pain (correct)

    • Which part of the gastrointestinal tract does Crohn's Disease mainly affect?

    <p>Right colon and distal ileum</p> Signup and view all the answers

    What skin lesions are typical in perianal disease, a common presentation of Crohn’s Disease?

    <p>Superficial ulcers</p> Signup and view all the answers

    Which aspect of Crohn's Disease is characterized by minute superficial ulcers surrounded by a halo of erythema?

    <p>Aphthous ulcers</p> Signup and view all the answers

    What is the hallmark of ulcerative colitis?

    <p>Sharp transition between diseased and uninvolved colon segments</p> Signup and view all the answers

    Which genetic determinants play a less significant role in ulcerative colitis compared to Crohn’s disease?

    <p>Continuous and symmetrical involvement</p> Signup and view all the answers

    Which gene mutation is NOT associated with ulcerative colitis, but seen in Crohn's disease patients?

    <p>NOD2/CARD15</p> Signup and view all the answers

    Which symptom is NOT typically associated with the clinical presentation of ulcerative colitis?

    <p>Weight gain</p> Signup and view all the answers

    Why is smoking considered protective against ulcerative colitis?

    <p>It reduces inflammation in the colon</p> Signup and view all the answers

    What type of inflammation is characteristic of ulcerative colitis?

    <p>Superficial</p> Signup and view all the answers

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