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Inflammatory Bowel Disease Risk Factors and Genetic Factors Quiz

Test your knowledge on the risk factors and genetic factors associated with Inflammatory Bowel Disease (IBD) such as concordance rates among twins, risk among first-degree relatives, and the abnormal NOD2/CARD15 gene. Learn about the impact of smoking on IBD and its association with UC and CD.

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@IllustriousUranium
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Questions and Answers

What is the concordance rate among monozygotic twins for Crohn's Disease (CD) compared to Ulcerative Colitis (UC)?

70% for CD and 20% for UC

Which gene is abnormal in Inflammatory Bowel Disease (IBD) and functions as an intracellular sensor of bacteria?

NOD2/CARD15 gene

What is a common clinical presentation of Crohn’s Disease?

Right lower quadrant pain

Which part of the gastrointestinal tract does Crohn's Disease mainly affect?

<p>Right colon and distal ileum</p> Signup and view all the answers

What skin lesions are typical in perianal disease, a common presentation of Crohn’s Disease?

<p>Superficial ulcers</p> Signup and view all the answers

Which aspect of Crohn's Disease is characterized by minute superficial ulcers surrounded by a halo of erythema?

<p>Aphthous ulcers</p> Signup and view all the answers

What is the hallmark of ulcerative colitis?

<p>Sharp transition between diseased and uninvolved colon segments</p> Signup and view all the answers

Which genetic determinants play a less significant role in ulcerative colitis compared to Crohn’s disease?

<p>Continuous and symmetrical involvement</p> Signup and view all the answers

Which gene mutation is NOT associated with ulcerative colitis, but seen in Crohn's disease patients?

<p>NOD2/CARD15</p> Signup and view all the answers

Which symptom is NOT typically associated with the clinical presentation of ulcerative colitis?

<p>Weight gain</p> Signup and view all the answers

Why is smoking considered protective against ulcerative colitis?

<p>It reduces inflammation in the colon</p> Signup and view all the answers

What type of inflammation is characteristic of ulcerative colitis?

<p>Superficial</p> Signup and view all the answers

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