Industrial Pharmacy Lab 2: Rheology Part I

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10 Questions

What is the primary purpose of adding a lubricant to a powder mixture?

To reduce friction between particles and machine walls

Which of the following statements about glidants is true?

Glidants can make the particle surfaces smoother

What is a potential issue with using high concentrations of lubricants and glidants?

They can cause stickiness and poor flowability

Which of the following is a factor that can improve powder flowability?

Converting the powder into granules with uniform size and shape

What is a potential issue with over-drying particles during the drying process?

It can convert the granules into fine powder again

Which of the following techniques can produce spherical, free-flowing granules?

Spray drying

What is the purpose of granulation in improving powder flowability?

To convert fine powder into granules with uniform size and shape

Which of the following statements about the concentration of lubricants and glidants is true?

The concentration is very critical and needs to be carefully controlled

What is the purpose of drying particles in improving powder flowability?

To remove excess moisture, which can improve flowability

Which of the following is not mentioned as a mechanism by which glidants improve powder flowability?

Increasing the electrostatic charge between particles

Explore the principles of rheology as applied to pharmaceutical materials in the preparation, development, and evaluation of dosage forms. Understand the importance of studying flow properties for manufacturing tablets and capsules.

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