Industrial Pharmacy Lab 2: Rheology Part I
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Questions and Answers

What is the primary purpose of adding a lubricant to a powder mixture?

  • To increase the moisture content of the particles
  • To reduce friction between particles and machine walls (correct)
  • To convert the powder into granules
  • To make the particle surfaces more smooth

    • Which of the following statements about glidants is true?

  • Glidants can increase the electrostatic charge adhesion between particles
  • Glidants can make the particle surfaces smoother (correct)
  • Large concentrations of glidants are preferred for better flowability
  • Glidants can help reduce the moisture adsorbed on particle surfaces

    • What is a potential issue with using high concentrations of lubricants and glidants?

  • They can cause stickiness and poor flowability (correct)
  • They can increase the electrostatic charge between particles
  • They can reduce the moisture content of the particles
  • They can cause the particles to become too smooth

    • Which of the following is a factor that can improve powder flowability?

    <p>Converting the powder into granules with uniform size and shape</p> Signup and view all the answers

    What is a potential issue with over-drying particles during the drying process?

    <p>It can convert the granules into fine powder again</p> Signup and view all the answers

    Which of the following techniques can produce spherical, free-flowing granules?

    <p>Spray drying</p> Signup and view all the answers

    What is the purpose of granulation in improving powder flowability?

    <p>To convert fine powder into granules with uniform size and shape</p> Signup and view all the answers

    Which of the following statements about the concentration of lubricants and glidants is true?

    <p>The concentration is very critical and needs to be carefully controlled</p> Signup and view all the answers

    What is the purpose of drying particles in improving powder flowability?

    <p>To remove excess moisture, which can improve flowability</p> Signup and view all the answers

    Which of the following is not mentioned as a mechanism by which glidants improve powder flowability?

    <p>Increasing the electrostatic charge between particles</p> Signup and view all the answers

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