Industrial Pharmacy Lab 2: Rheology Part I
18 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary purpose of studying the rheological properties of pharmaceutical materials?

  • To understand the flow properties of materials during the preparation and development of pharmaceutical dosage forms. (correct)
  • To maintain a consistent flow rate of particles during the filling of tablets and capsules.
  • To determine the intermolecular forces acting on the surface of powder particles.
  • To ensure the constant weight of powder reaching the die during tablet compression.

    • What is the key reason for ensuring a constant flow rate of particles during the filling of tablets and capsules?

  • To achieve uniform weight of the final products.
  • To reduce the intermolecular forces acting on the surface of powder particles.
  • To prevent variations in the amount of granules filled in the die during compression. (correct)
  • To maintain constant content uniformity and good bioavailability.

    • What is the primary difference between a freely flowable powder and a non-freely (sticky) flowable powder?

  • The intermolecular forces acting on the particle surface. (correct)
  • The bulk density of the powder.
  • The compressibility of the powder.
  • The particle size distribution.

    • Which of the following is a key factor that can reduce the flow rate of powder particles?

    <p>Increased Van der Waals forces on the particle surface.</p> Signup and view all the answers

    What is the main consequence of having a good flow rate of powder particles during tablet compression?

    <p>All of the above.</p> Signup and view all the answers

    Which of the following is the MOST important reason for studying the rheological properties of pharmaceutical materials?

    <p>To ensure the consistent filling of tablets and capsules.</p> Signup and view all the answers

    What is the primary reason why irregular-shaped particles have poor flowability?

    <p>Irregular particles have rough surfaces that increase friction between particles.</p> Signup and view all the answers

    Which of the following is NOT a factor that reduces the flow rate of powders?

    <p>Electrical charge on the particles</p> Signup and view all the answers

    What is the relationship between particle size and flow rate, as described in the text?

    <p>There is an optimal particle size range for good flowability.</p> Signup and view all the answers

    How do frictional (electrostatic) forces affect the flowability of powders?

    <p>Frictional forces decrease the flowability of powders.</p> Signup and view all the answers

    What is the effect of moisture on the flowability of powders?

    <p>Moisture can either improve or reduce the flowability of powders, depending on the amount.</p> Signup and view all the answers

    Which of the following statements about the factors affecting the flowability of powders is NOT supported by the text?

    <p>Increasing the moisture content of powders always improves their flowability.</p> Signup and view all the answers

    Which of the following is NOT a mechanism by which glidants improve powder flowability?

    <p>Increasing the moisture content on the particle surface</p> Signup and view all the answers

    What is the primary reason for the need to carefully control the concentration of lubricants and glidants?

    <p>Their hydrophobic nature can cause stickiness and poor flowability at high concentrations</p> Signup and view all the answers

    Which of the following statements about granulation is NOT true?

    <p>It increases the flowability of powders by reducing particle surface area</p> Signup and view all the answers

    Which of the following is a potential issue with over-drying powders during the drying process?

    <p>It can convert granules back into fine powder with poor flowability</p> Signup and view all the answers

    Which technique is mentioned in the text for altering particle shape and texture to produce spherical, free-flowing granules?

    <p>Spray drying</p> Signup and view all the answers

    What is the primary function of lubricants in improving powder flow?

    <p>Both reducing friction between particles and between particles and equipment surfaces</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser