7 Questions
What is the correct order of gene rearrangement in immunoglobulins for heavy and light chains?
Heavy gene rearrangement before light chain rearrangement
What is the function of the heavy chains in a B cell receptor (BCR)?
Deliver intracellular signals following antigen recognition
Which chromosome locus is responsible for the arrangement of Kappa light chain immunoglobulin genes?
Chromosome 2
Which of the following best describes the antigen receptors of naive B cells?
Membrane-bound IgM and IgD
What is the role of D gene segments in immunoglobulin gene rearrangement?
Not found on light chain loci, only on heavy chain locus
What is correct about the gene arrangement of heavy chain immunoglobulin genes?
Heavy genes are expressed before light genes
How does combinatorial diversity occur in antigen receptor genes?
Generated by different rearrangement combinations of V, D, and J gene segments
Test your knowledge on the genetic process involving V(D)J gene segments and constant domains in the immunoglobulin heavy chain. Learn about the arrangement of variable, diversity, joining, and constant gene segments on chromosome 14 locus.
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