Immunoglobulin Functions Quiz
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Questions and Answers

What is the primary reason for the adaptive immune subsystem being the most important layer of defense?

  • Its ability to generate resistance proportional to the threat (correct)
  • Its ability to respond automatically to a diverse set of microorganisms
  • Its lack of flexibility in responding optimally
  • Its ability to cause substantial tissue damage

Which type of immunity is directed against extracellular invaders?

  • Innate immunity
  • Antibody (humoral) immunity (correct)
  • Adaptive immunity
  • Cell-mediated immunity

What is the function of regulatory cells and cytokines in the immune system?

  • To ensure that adaptive immune responses occur only under appropriate circumstances (correct)
  • To cause substantial tissue damage
  • To generate resistance proportional to the threat
  • To respond automatically to microbial invasion

What must occur sequentially for an antibody-mediated or cell-mediated immune response to occur?

<p>The capture and processing of foreign antigens, followed by recognition by lymphocytes (B)</p> Signup and view all the answers

What is the role of regulatory T cells (Treg cells)?

<p>Inhibit conventional immune responses and prevent the development of autoimmunity (A)</p> Signup and view all the answers

How do immune cells communicate with each other?

<p>Through physical contact and exchange of signals through receptors (D)</p> Signup and view all the answers

What is the primary function of cytokines in immune cell signaling?

<p>Promoting the synthesis of specific proteins in the target cell (A)</p> Signup and view all the answers

What is the role of interferons in immune cell interactions?

<p>Have substantial antiviral activity (B)</p> Signup and view all the answers

How do T cells protect animals against intracellular invaders?

<p>By mounting a cell-mediated response (A)</p> Signup and view all the answers

What makes it difficult to predict how a specific target cell will respond to cytokines?

<p>The complex mixtures of hundreds of different cytokines acting together (C)</p> Signup and view all the answers

Which type of dendritic cell triggers antibody formation?

<p>DC2 cells (C)</p> Signup and view all the answers

What type of immune response is promoted by Th1 cells?

<p>Cell-mediated immunity (C)</p> Signup and view all the answers

Which cytokine is secreted by Th2 cells?

<p>IL-4 (C)</p> Signup and view all the answers

What is the role of cytotoxic T cells in combating viral infections?

<p>Killing virus-infected cells (B)</p> Signup and view all the answers

Which protein do cytotoxic T cells express on their surface?

<p>CD8 (C)</p> Signup and view all the answers

What is the function of costimulation from a helper T cell for cytotoxic T cells?

<p>Enabling their function (D)</p> Signup and view all the answers

Which type of cell does IFN-gamma from Th1 cells activate to destroy intracellular bacteria?

<p>M1 macrophages (C)</p> Signup and view all the answers

What does the adaptive immunity rely on for enhanced and accelerated response against invading microbes?

<p>Recognition of previously encountered microbes (D)</p> Signup and view all the answers

What is the role of memory T cells in immunologic memory?

<p>Mounting enhanced immune responses (A)</p> Signup and view all the answers

Why do most cytotoxic T cells die once they are no longer needed?

<p>Lack of costimulation from helper T cells (A)</p> Signup and view all the answers

What is the main reason for immunologic memory resulting from adaptive immunity?

<p>Recognition of previously encountered microbes (D)</p> Signup and view all the answers

What is the role of antibodies in the immune system?

<p>They bind to foreign molecules and mark them for destruction by phagocytic cells (D)</p> Signup and view all the answers

Where are memory B cells located within an animal?

<p>They can persist within an animal for many years (A)</p> Signup and view all the answers

What is the role of T helper type 2 cells in the immune system?

<p>Provide assistance to B cells for antibody production (D)</p> Signup and view all the answers

Where are B cells and plasma cells located within the body?

<p>Within lymphoid organs (C)</p> Signup and view all the answers

Which class of immunoglobulin is usually confined to the bloodstream?

<p>IgM (D)</p> Signup and view all the answers

What triggers B cells to respond by mounting immune responses?

<p>Foreign antigens (B)</p> Signup and view all the answers

What is the main role of plasma cells?

<p>Synthesize and secrete enormous quantities of antibodies (B)</p> Signup and view all the answers

Where do B cells originate?

<p>Bone marrow (C)</p> Signup and view all the answers

What happens when an animal encounters an antigen for the second time?

<p>The memory B cells respond rapidly (B)</p> Signup and view all the answers

What must happen for a B cell to respond to a bound foreign antigen?

<p>It must also receive costimulation from helper T cells (B)</p> Signup and view all the answers

What is the role of IgG in the defense of the body?

<p>Eliminating organisms that succeed in penetrating deep into the body (B)</p> Signup and view all the answers

What is the function of IgE?

<p>To control invasion by parasites and mediate acute inflammation in allergic states (B)</p> Signup and view all the answers

Where are Langerhans cells primarily found?

<p>Dermis (C)</p> Signup and view all the answers

What is the role of MHC molecules?

<p>To determine whether an individual can respond to a foreign antigen (A)</p> Signup and view all the answers

Why do surviving T cells respond only to foreign antigens?

<p>Because normal body component receptors on T cells are killed during maturation in the thymus (A)</p> Signup and view all the answers

What is the main function of dendritic cells?

<p>To capture, process, and present foreign antigens to helper T cells (D)</p> Signup and view all the answers

What is the primary function of IgA on body surfaces?

<p>To complement the physical barriers of the body and block microbial invasion (B)</p> Signup and view all the answers

What is the significance of receptor molecules called MHC molecules on dendritic cells?

<p>They carry antigen-receptor complexes to the dendritic cell surface (A)</p> Signup and view all the answers

How are antibody responses regulated?

<p>By binding antigen fragments presented by dendritic cells (A)</p> Signup and view all the answers

What is the role of IgD in the immune response?

<p>To play a role in the response to the normal microbiota (D)</p> Signup and view all the answers

What happens if an animal lacks MHC molecules that can bind a specific antigen?

<p>It will be unable to respond to that specific antigen. (D)</p> Signup and view all the answers

What is the characteristic of MHC molecules expressed within an individual animal?

<p>They can bind many, perhaps most, foreign antigens. (B)</p> Signup and view all the answers

What happens when a dendritic cell presents MHC-associated antigen to T cells?

<p>All T cells with appropriate receptors will bind to the dendritic cell. (B)</p> Signup and view all the answers

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