Immunodeficiency: Innate Examples

1-phagocytes - complement - NK cells

Migration - engulf - intracellular-killing

Leukocyte adhesion deficiency - LAD 1 and LAD 2

<p>Defectin CD18 on neutrophilc - macrophage-dendritic cells</p> Signup and view all the answers

<p>ICAM -1 on activated endothelium</p> Signup and view all the answers

<p>Defect defect in production of CD 15 S present leukocytes it’s a ligand for selection on activated endothelium</p> Signup and view all the answers

<p>what defective adherence to endothelium surface and increases susceptibility to bacterial infection and new pus formation?</p> Signup and view all the answers

<p>Chronic granumalatous disease and chediak higashi syndrome</p> Signup and view all the answers

<p> X link disease defect in NADPH oxidation system or G6PD hydrogen and myeloperoxidase</p> Signup and view all the answers

<p>Okay, no radicals so the killing decreases so chronic bacterial infection and recruitment of more phagocytes so the lesion resembling granny Lomas is formed</p> Signup and view all the answers

<p>Autosomal recessive it happened due to defect in fusion of phagosomes end lysosomes in neutrophil macrophage and dentritic cells</p> Signup and view all the answers