Immune-Mediated Polyarthritis (IMPA) in Dogs
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Questions and Answers

Which is not a goal of therapy for Immune-Mediated Polyarthritis (IMPA)?

  • Resolution of inflammation
  • Promotion of muscle mass reduction (correct)
  • Supportive care
  • Pain control
  • What is the hallmark of Immune-Mediated Polyarthritis (IMPA) in synovial fluid analysis?

  • Septic synovial fluid
  • Suppurative synovial fluid
  • Lymphocytic synovial fluid (correct)
  • Clear synovial fluid
  • Which medication is commonly used for Immune-Mediated Polyarthritis (IMPA) treatment, but can lead to muscle mass reduction and increased ligament laxity in large/giant breed dogs?

  • NSAIDs
  • Mycophenolate
  • Prednisone (correct)
  • Cyclosporine
  • Which agents have shown promise in achieving remission in Immune-Mediated Polyarthritis (IMPA) cases as adjunctive therapy?

    <p>Leflunomide and cyclosporine</p> Signup and view all the answers

    What is an appropriate choice as a second agent to prednisone therapy in Immune-Mediated Polyarthritis (IMPA) cases?

    <p>Azathioprine</p> Signup and view all the answers

    What is a reliable marker for monitoring IMPA, as it correlates with joint fluid cellularity and joint mobility, and decreases with treatment efficacy?

    <p>Plasma C-Reactive Protein</p> Signup and view all the answers

    What is important for managing IMPA during the initial treatment phase?

    <p>Limiting activity</p> Signup and view all the answers

    What type of synovial fluid is not a hallmark of Immune-Mediated Polyarthritis (IMPA)?

    <p>Hyaluronic acid-rich synovial fluid</p> Signup and view all the answers

    Which medication can be used for anti-inflammatory and analgesic support in Immune-Mediated Polyarthritis (IMPA) cases where steroids are not suitable?

    <p>Gabapentin</p> Signup and view all the answers

    What involves gross and cytologic analysis including color, turbidity, viscosity, protein, cell count, and cytology?

    <p>Synovial fluid analysis</p> Signup and view all the answers

    What is a potential consequence of high steroid doses in large/giant breed dogs during Immune-Mediated Polyarthritis (IMPA) treatment?

    <p>Reduced muscle mass</p> Signup and view all the answers

    Which type of Immune-Mediated Polyarthritis (IMPA) is the most common?

    <p>Type 1 - Idiopathic</p> Signup and view all the answers

    What is the hallmark of Immune-Mediated Polyarthritis (IMPA) in synovial fluid analysis?

    <p>Antigen-antibody complex deposition</p> Signup and view all the answers

    What is a potential consequence of high steroid doses in large/giant breed dogs during Immune-Mediated Polyarthritis (IMPA) treatment?

    <p>Muscle mass reduction</p> Signup and view all the answers

    What involves gross and cytologic analysis including color, turbidity, viscosity, protein, cell count, and cytology?

    <p>Joint taps</p> Signup and view all the answers

    Which medication is commonly used for Immune-Mediated Polyarthritis (IMPA) treatment, but can lead to muscle mass reduction and increased ligament laxity in large/giant breed dogs?

    <p>Prednisone</p> Signup and view all the answers

    Which is not a cause of Immune-Mediated Polyarthritis (IMPA)?

    <p>Severe immune-complex deposition</p> Signup and view all the answers

    What is a reliable marker for monitoring IMPA, as it correlates with joint fluid cellularity and joint mobility, and decreases with treatment efficacy?

    <p>Inflammatory synovial fluid</p> Signup and view all the answers

    What is important for managing IMPA during the initial treatment phase?

    <p>Rule out secondary causes</p> Signup and view all the answers

    Which medication can be used for anti-inflammatory and analgesic support in Immune-Mediated Polyarthritis (IMPA) cases where steroids are not suitable?

    <p>Firocoxib</p> Signup and view all the answers

    Which agents have shown promise in achieving remission in Immune-Mediated Polyarthritis (IMPA) cases as adjunctive therapy?

    <p>Immunosuppressants</p> Signup and view all the answers

    What type of synovial fluid is not a hallmark of Immune-Mediated Polyarthritis (IMPA)?

    <p>Non-inflammatory</p> Signup and view all the answers

    What is a potential consequence of high steroid doses in large/giant breed dogs during Immune-Mediated Polyarthritis (IMPA) treatment?

    <p>Muscle mass reduction</p> Signup and view all the answers

    Study Notes

    Immune-Mediated Polyarthritis in Dogs: Diagnosis and Treatment

    • Differential diagnosis for joint taps includes ruling out secondary causes such as infectious bacterial, fungal, and neoplastic conditions
    • Synovial fluid analysis involves gross and cytologic analysis including color, turbidity, viscosity, protein, cell count, and cytology
    • Non-septic, suppurative, or lymphocytic synovial fluid is the hallmark of Immune-Mediated Polyarthritis (IMPA)
    • Goals of therapy for IMPA involve resolution of inflammation, pain control, and supportive care
    • Steroids are commonly used for IMPA treatment, but high doses in large/giant breed dogs can lead to muscle mass reduction and increased ligament laxity
    • Adjunctive agents such as leflunomide and cyclosporine have shown promise in achieving remission in IMPA cases
    • NSAIDs, tramadol, and gabapentin can be used for anti-inflammatory and analgesic support in cases where steroids are not suitable
    • Cyclosporine, mycophenolate, azathioprine, and leflunomide are appropriate choices as second agents to prednisone therapy
    • Neuropathic pain medications and NMDA antagonists can be used for pain management in IMPA cases
    • Hydration support and limiting activity during the initial treatment phase are important for managing IMPA
    • Monitoring IMPA involves repeat joint taps, considering plasma C-Reactive Protein, and assessing clinical signs for remission
    • Plasma C-Reactive Protein is a reliable marker for monitoring IMPA, as it correlates with joint fluid cellularity and joint mobility, and decreases with treatment efficacy

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    Description

    Test your knowledge on the diagnosis and treatment of Immune-Mediated Polyarthritis (IMPA) in dogs with this informative quiz. Explore differential diagnosis, synovial fluid analysis, therapy goals, treatment options, monitoring, and more.

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