24 Questions
During a parasite infection, which type of immune cells are typically elevated in a complete blood cell count?
Eosinophils
Which type of immune cells are usually elevated in a complete blood cell count during a bacterial infection?
Neutrophils
Where do B cells originate from for generative lymphoid organ development and maturation?
Bone marrow
Where do T cells originate from for generative lymphoid organ development and maturation?
Thymus
Which immune cells recirculate through blood and lymph after maturity, waiting for a specific antigen?
B cells
Where in the body does positive and negative selection occur with T cells to ensure an appropriate immune response?
Thymus
Which secondary/peripheral lymphoid organs do T cells primarily stay in after positive and negative selection?
Thymus
Where do B cells move after maturity to concentrate and wait for a specific antigen recognition?
(Blood) Lymph nodes and spleen
Which kind of lymphocytes are more flexible and have more tolerance after maturation?
(Mature) Lymphocytes
What kind of immune cells are elevated during a parasite infection?
Neutrophils
How do lymphocytes move from the bone marrow into the lymph nodes?
Via bloodstream
Where does the development and maturation of B cells occur for generative lymphoid organs?
Bone marrow
Where do lymphocytes enter the lymph nodes?
Through the lymph node capsule
What role do plasma cells play in the immune response?
Secrete antibodies
What is the primary function of a Natural Killer (NK) cell?
Kill virus-infected cells
What is the main function of dendritic cells?
Initiate adaptive immune response
How do naïve B and T cells leave the lymph nodes?
Through efferent lymphatic vessels
What is the function of integrin molecules during phagocyte migration?
Allow for firm adhesion to endothelium
Which molecule is directly associated with the inhibition of virus gene expression and assembly?
Interferon
What is the role of pattern recognition receptors (PRRs) in the immune system?
Recognize microbial patterns
What initiates the adaptive immune response in relation to dendritic cells?
Activating T cells
What are the two main functions of dendritic cells?
Respond to microbes by secreting cytokines to initiate inflammation and stimulate adaptive immune system.
What is the difference between a naïve B cell and a plasma cell?
Naïve B cell is a B cell that has not yet been exposed to an antigen, and plasma cells are a type of effector cell that secrete antibodies.
What kind of receptor recognizes microbial patterns such as a bacterial cell wall lipid?
Pattern Recognition Receptors (PRRs)
Test your knowledge of immune cells and their responses to parasite and bacterial infections. Explore topics such as elevated blood cell counts, lymphocyte movement from the bone marrow, and cell development and maturation.
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