Hepatitis B and AIHA: Clinical Features and Transmission

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What is a characteristic of Autoanti-I?

It is directed against the I antigen found on the RBCs of rare donor bloods.

It is directed against the I antigen found on the RBCs of most random donor bloods. (correct)

It is an alloantibody found in A1 or A1B individuals.

It is a benign warm autoantibody.

What is the most common type of autoantibody found in A1 or A1B individuals?

Anti-I

Anti-i

Anti-H (correct)

Anti-Pr

What is the typical temperature at which the IgM autoantibody reacts in Cold Hemagglutinin Disease?

At 4°C, 25°C, and 31°C (correct)

Only at 31°C

Only at 25°C

Only at 4°C

What is a symptom of Cold Hemagglutinin Disease?

Acrocyanosis in hands and feet Signup and view all the answers

What is a laboratory finding in Cold Hemagglutinin Disease?

Positive DAT Signup and view all the answers

What is a complication of Cold Hemagglutinin Disease?

All of the above Signup and view all the answers

Which of the following is a mode of transmission of Hepatitis B?

Multipleneedle use (drug abuse) Signup and view all the answers

What is the average incubation period of Hepatitis B?

60-90 days Signup and view all the answers

What is the characteristic of an autoantibody in Autoimmune Hemolytic Anemia (AIHA)?

IgG subclass reactivity Signup and view all the answers

What is a symptom of Hemolytic Anemia?

Jaundice Signup and view all the answers

What is the diagnostic test for AIHA?

Serologic testing Signup and view all the answers

What is a factor that determines the occurrence of AIHA?

Thermal amplitude of Ab reactivity Signup and view all the answers

What is the typical onset of Warm Autoimmune Hemolytic Anemia (WAIHA)?

Insidious and triggered by infection or trauma Signup and view all the answers

What is the significance of reticulocytopenia in WAIHA?

It is associated with high mortality rate Signup and view all the answers

What is the importance of choosing the 'least incompatible' RBCs for transfusion in WAIHA?

To ensure compatibility with alloantibodies in the patient's serum Signup and view all the answers

Hepatitis B and AIHA: Clinical Features and Transmission

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Questions and Answers

What is a characteristic of Autoanti-I?

What is the most common type of autoantibody found in A1 or A1B individuals?

What is the typical temperature at which the IgM autoantibody reacts in Cold Hemagglutinin Disease?

What is a symptom of Cold Hemagglutinin Disease?

What is a laboratory finding in Cold Hemagglutinin Disease?

What is a complication of Cold Hemagglutinin Disease?

Which of the following is a mode of transmission of Hepatitis B?

What is the average incubation period of Hepatitis B?

What is the characteristic of an autoantibody in Autoimmune Hemolytic Anemia (AIHA)?

What is a symptom of Hemolytic Anemia?

What is the diagnostic test for AIHA?

What is a factor that determines the occurrence of AIHA?

What is the typical onset of Warm Autoimmune Hemolytic Anemia (WAIHA)?

What is the significance of reticulocytopenia in WAIHA?

What is the importance of choosing the 'least incompatible' RBCs for transfusion in WAIHA?

What is a common symptom of WAIHA?

What is the significance of increased unconjugated bilirubin in WAIHA?

Why is transfusion generally avoided in WAIHA?

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