Hepatitis B and AIHA: Clinical Features and Transmission
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Questions and Answers

What is a characteristic of Autoanti-I?

  • It is directed against the I antigen found on the RBCs of rare donor bloods.
  • It is directed against the I antigen found on the RBCs of most random donor bloods. (correct)
  • It is an alloantibody found in A1 or A1B individuals.
  • It is a benign warm autoantibody.

    • What is the most common type of autoantibody found in A1 or A1B individuals?

  • Anti-I
  • Anti-i
  • Anti-H (correct)
  • Anti-Pr

    • What is the typical temperature at which the IgM autoantibody reacts in Cold Hemagglutinin Disease?

  • At 4°C, 25°C, and 31°C (correct)
  • Only at 31°C
  • Only at 25°C
  • Only at 4°C

    • What is a symptom of Cold Hemagglutinin Disease?

    <p>Acrocyanosis in hands and feet</p> Signup and view all the answers

    What is a laboratory finding in Cold Hemagglutinin Disease?

    <p>Positive DAT</p> Signup and view all the answers

    What is a complication of Cold Hemagglutinin Disease?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is a mode of transmission of Hepatitis B?

    <p>Multipleneedle use (drug abuse)</p> Signup and view all the answers

    What is the average incubation period of Hepatitis B?

    <p>60-90 days</p> Signup and view all the answers

    What is the characteristic of an autoantibody in Autoimmune Hemolytic Anemia (AIHA)?

    <p>IgG subclass reactivity</p> Signup and view all the answers

    What is a symptom of Hemolytic Anemia?

    <p>Jaundice</p> Signup and view all the answers

    What is the diagnostic test for AIHA?

    <p>Serologic testing</p> Signup and view all the answers

    What is a factor that determines the occurrence of AIHA?

    <p>Thermal amplitude of Ab reactivity</p> Signup and view all the answers

    What is the typical onset of Warm Autoimmune Hemolytic Anemia (WAIHA)?

    <p>Insidious and triggered by infection or trauma</p> Signup and view all the answers

    What is the significance of reticulocytopenia in WAIHA?

    <p>It is associated with high mortality rate</p> Signup and view all the answers

    What is the importance of choosing the 'least incompatible' RBCs for transfusion in WAIHA?

    <p>To ensure compatibility with alloantibodies in the patient's serum</p> Signup and view all the answers

    What is a common symptom of WAIHA?

    <p>Pallor</p> Signup and view all the answers

    What is the significance of increased unconjugated bilirubin in WAIHA?

    <p>It is a sign of hemolysis</p> Signup and view all the answers

    Why is transfusion generally avoided in WAIHA?

    <p>Because it may accelerate hemolysis</p> Signup and view all the answers

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