Podcast
Questions and Answers
What is the primary mechanism by which alleles with reduced fitness can persist in a population?
What is the primary mechanism by which alleles with reduced fitness can persist in a population?
- Propagation via heterozygous genotypes (correct)
- Gene flow from a neighboring population
- Balancing selection
- Heterozygote advantage
What is the term for the phenomenon where the heterozygous genotype is fitter than either homozygote?
What is the term for the phenomenon where the heterozygous genotype is fitter than either homozygote?
- Balancing selection
- Heterozygote advantage (correct)
- Non-random mating
- Heterozygote disadvantage
What is the condition in which a missense mutation in the β-globin gene leads to the production of abnormal hemoglobin?
What is the condition in which a missense mutation in the β-globin gene leads to the production of abnormal hemoglobin?
- Sickle-cell anaemia (correct)
- Sickle-cell trait
- Thalassemia
- Malaria
What is the condition required for the maintenance of Hardy-Weinberg equilibrium?
What is the condition required for the maintenance of Hardy-Weinberg equilibrium?
What is the geographic distribution of the sickle-cell anaemia allele (HbS) strongly correlated with?
What is the geographic distribution of the sickle-cell anaemia allele (HbS) strongly correlated with?
What is the Hardy-Weinberg theorem in the context of a single gene with two alleles?
What is the Hardy-Weinberg theorem in the context of a single gene with two alleles?
What is the consequence of a population not being in Hardy-Weinberg equilibrium at a particular genetic locus?
What is the consequence of a population not being in Hardy-Weinberg equilibrium at a particular genetic locus?
What is the definition of evolution from a population genetics perspective?
What is the definition of evolution from a population genetics perspective?
What is the frequency of the normal homozygous individuals in a population, assuming the Irish population is in HWE at the CFTR genetic locus?
What is the frequency of the normal homozygous individuals in a population, assuming the Irish population is in HWE at the CFTR genetic locus?
What is the purpose of the Hardy-Weinberg theorem in the context of predicting the incidence of inherited disease?
What is the purpose of the Hardy-Weinberg theorem in the context of predicting the incidence of inherited disease?
What is the frequency of the AA genotype in a population at Hardy-Weinberg equilibrium?
What is the frequency of the AA genotype in a population at Hardy-Weinberg equilibrium?
Cystic fibrosis is an autosomal recessive disorder. What is the genotype of an individual who is a carrier of the disease?
Cystic fibrosis is an autosomal recessive disorder. What is the genotype of an individual who is a carrier of the disease?
A population is in Hardy-Weinberg equilibrium. If the frequency of the A allele is 0.6, what is the frequency of the a allele?
A population is in Hardy-Weinberg equilibrium. If the frequency of the A allele is 0.6, what is the frequency of the a allele?
The Hardy-Weinberg theorem can be used to predict the incidence of inherited diseases. What is the frequency of the aa genotype in a population where the frequency of the a allele is 0.2?
The Hardy-Weinberg theorem can be used to predict the incidence of inherited diseases. What is the frequency of the aa genotype in a population where the frequency of the a allele is 0.2?
What is the relationship between the allele frequencies p and q in a population at Hardy-Weinberg equilibrium?
What is the relationship between the allele frequencies p and q in a population at Hardy-Weinberg equilibrium?
What is the frequency of the Fy0 allele in African populations?
What is the frequency of the Fy0 allele in African populations?
What is the effect of diploidy on genetic variation in a population?
What is the effect of diploidy on genetic variation in a population?
What is the effect of balancing selection on genetic variation in a population?
What is the effect of balancing selection on genetic variation in a population?
What is the susceptibility to malaria associated with the Fya allele?
What is the susceptibility to malaria associated with the Fya allele?
What is the role of natural selection in shaping a population's genotype frequencies?
What is the role of natural selection in shaping a population's genotype frequencies?
What is the reason for the increased frequency of the RP allele in Tristan da Cunha compared to Britain?
What is the reason for the increased frequency of the RP allele in Tristan da Cunha compared to Britain?
What is the effect of gene flow between populations on their genetic structure?
What is the effect of gene flow between populations on their genetic structure?
What is the result of gene flow from population 1 (fixed for the a allele) to population 2 (fixed for the A allele)?
What is the result of gene flow from population 1 (fixed for the a allele) to population 2 (fixed for the A allele)?
What is the purpose of the Hardy-Weinberg theorem in predicting the incidence of inherited disease?
What is the purpose of the Hardy-Weinberg theorem in predicting the incidence of inherited disease?
What is the effect of inbreeding on the genotype frequencies in a population?
What is the effect of inbreeding on the genotype frequencies in a population?
In the context of the Hardy-Weinberg theorem, what is the effect of self-fertilisation on the allele frequencies?
In the context of the Hardy-Weinberg theorem, what is the effect of self-fertilisation on the allele frequencies?
What is the minimum number of generations required to observe the effects of genetic drift in a small population?
What is the minimum number of generations required to observe the effects of genetic drift in a small population?
What is the primary assumption of the Hardy-Weinberg theorem regarding population size?
What is the primary assumption of the Hardy-Weinberg theorem regarding population size?
Which of the following conditions is NOT required for the maintenance of Hardy-Weinberg equilibrium?
Which of the following conditions is NOT required for the maintenance of Hardy-Weinberg equilibrium?
What is the likely outcome of the founder effect on the genetic makeup of a new colony?
What is the likely outcome of the founder effect on the genetic makeup of a new colony?
What is the reason for the lack of diversity at the major histocompatibility complex (MHC) genetic locus in cheetahs?
What is the reason for the lack of diversity at the major histocompatibility complex (MHC) genetic locus in cheetahs?
What is the probability of being affected by Retinitis Pigmentosa (RP) in the Tristan da Cunha population?
What is the probability of being affected by Retinitis Pigmentosa (RP) in the Tristan da Cunha population?
What is the frequency of the allele associated with Retinitis Pigmentosa (RP) in Britain?
What is the frequency of the allele associated with Retinitis Pigmentosa (RP) in Britain?
What is the term for the phenomenon where a few individual organisms colonise a new habitat?
What is the term for the phenomenon where a few individual organisms colonise a new habitat?
What is the likely consequence of a population experiencing a bottleneck effect?
What is the likely consequence of a population experiencing a bottleneck effect?
What is the condition caused by mutations in the rhodopsin gene (RHO) on HSA3?
What is the condition caused by mutations in the rhodopsin gene (RHO) on HSA3?
What is the effect of the founder effect on the genetic variation of a population?
What is the effect of the founder effect on the genetic variation of a population?
What is the probability of being a carrier of the allele associated with Retinitis Pigmentosa (RP) in Tristan da Cunha?
What is the probability of being a carrier of the allele associated with Retinitis Pigmentosa (RP) in Tristan da Cunha?
What is the term for the phenomenon where a population experiences a severe reduction in size, leading to a loss of genetic variation?
What is the term for the phenomenon where a population experiences a severe reduction in size, leading to a loss of genetic variation?
What is the probability of being a carrier of an autosomal recessive disease in a population where the frequency of the recessive allele is 0.4?
What is the probability of being a carrier of an autosomal recessive disease in a population where the frequency of the recessive allele is 0.4?
In a population at Hardy-Weinberg equilibrium, if the frequency of the AA genotype is 0.36, what is the frequency of the A allele?
In a population at Hardy-Weinberg equilibrium, if the frequency of the AA genotype is 0.36, what is the frequency of the A allele?
What is the genotypic frequency of individuals affected by an autosomal recessive disease in a population where the frequency of the recessive allele is 0.2?
What is the genotypic frequency of individuals affected by an autosomal recessive disease in a population where the frequency of the recessive allele is 0.2?
In a population at Hardy-Weinberg equilibrium, if the frequency of the A allele is 0.7, what is the frequency of the Aa genotype?
In a population at Hardy-Weinberg equilibrium, if the frequency of the A allele is 0.7, what is the frequency of the Aa genotype?
What is the purpose of the Hardy-Weinberg theorem in the context of predicting the incidence of inherited disease?
What is the purpose of the Hardy-Weinberg theorem in the context of predicting the incidence of inherited disease?
What is the probability of an individual being homozygous recessive for the RP allele in a population where the frequency of the RP allele is 0.7?
What is the probability of an individual being homozygous recessive for the RP allele in a population where the frequency of the RP allele is 0.7?
In a population at Hardy-Weinberg equilibrium, what is the frequency of the heterozygous genotype if the frequency of the A allele is 0.8 and the frequency of the a allele is 0.2?
In a population at Hardy-Weinberg equilibrium, what is the frequency of the heterozygous genotype if the frequency of the A allele is 0.8 and the frequency of the a allele is 0.2?
What is the effect of gene flow on the genotype frequencies in a population that was previously fixed for the a allele?
What is the effect of gene flow on the genotype frequencies in a population that was previously fixed for the a allele?
In a population at Hardy-Weinberg equilibrium, what is the frequency of the Aa genotype if the frequency of the A allele is 0.9 and the frequency of the a allele is 0.1?
In a population at Hardy-Weinberg equilibrium, what is the frequency of the Aa genotype if the frequency of the A allele is 0.9 and the frequency of the a allele is 0.1?
What is the effect of genetic drift on the allele frequencies in a population that has undergone a bottleneck effect?
What is the effect of genetic drift on the allele frequencies in a population that has undergone a bottleneck effect?
What is the primary reason why natural selection does not eliminate genetic variation in a population?
What is the primary reason why natural selection does not eliminate genetic variation in a population?
What is the expected frequency of the Fy0 allele in a population where malaria disease persists?
What is the expected frequency of the Fy0 allele in a population where malaria disease persists?
What is the effect of balancing selection on genetic variation in a population?
What is the effect of balancing selection on genetic variation in a population?
What is the role of diploidy in preserving genetic variation in a population?
What is the role of diploidy in preserving genetic variation in a population?
What is the purpose of the Hardy-Weinberg theorem in predicting the incidence of inherited disease?
What is the purpose of the Hardy-Weinberg theorem in predicting the incidence of inherited disease?
What is the consequence of a deviation from Hardy-Weinberg Equilibrium in a population?
What is the consequence of a deviation from Hardy-Weinberg Equilibrium in a population?
What is the probability of being a carrier of cystic fibrosis in the Irish population if the frequency of the mutated CFTR allele is 0.2?
What is the probability of being a carrier of cystic fibrosis in the Irish population if the frequency of the mutated CFTR allele is 0.2?
If the frequency of the normal CFTR allele is 0.8, what is the frequency of heterozygous carriers in the Irish population?
If the frequency of the normal CFTR allele is 0.8, what is the frequency of heterozygous carriers in the Irish population?
What is the requirement for the Hardy-Weinberg theorem to be applicable to a population?
What is the requirement for the Hardy-Weinberg theorem to be applicable to a population?
What is the consequence of a change in the allele frequencies in a population over time?
What is the consequence of a change in the allele frequencies in a population over time?
What is the genotype frequency of Aa in a population at Hardy-Weinberg equilibrium, if the frequency of the A allele is 0.4 and the frequency of the a allele is 0.6?
What is the genotype frequency of Aa in a population at Hardy-Weinberg equilibrium, if the frequency of the A allele is 0.4 and the frequency of the a allele is 0.6?
In a population, the frequency of the sickle-cell anaemia allele (HbS) is 0.2. What is the frequency of the AA genotype?
In a population, the frequency of the sickle-cell anaemia allele (HbS) is 0.2. What is the frequency of the AA genotype?
What is the effect of inbreeding on the genotype frequencies in a population?
What is the effect of inbreeding on the genotype frequencies in a population?
What is the probability of being affected by sickle-cell anaemia in a population where the frequency of the HbS allele is 0.2?
What is the probability of being affected by sickle-cell anaemia in a population where the frequency of the HbS allele is 0.2?
What is the condition required for the Hardy-Weinberg theorem to be applied?
What is the condition required for the Hardy-Weinberg theorem to be applied?
What is the expected frequency of the Aa genotype in a population that is in Hardy-Weinberg equilibrium, if the frequency of the A allele is 0.5?
What is the expected frequency of the Aa genotype in a population that is in Hardy-Weinberg equilibrium, if the frequency of the A allele is 0.5?
A population is in Hardy-Weinberg equilibrium, with allele frequencies p = 0.7 and q = 0.3. What is the expected frequency of the AA genotype?
A population is in Hardy-Weinberg equilibrium, with allele frequencies p = 0.7 and q = 0.3. What is the expected frequency of the AA genotype?
A population is not in Hardy-Weinberg equilibrium due to inbreeding. What is the expected effect on the genotype frequencies?
A population is not in Hardy-Weinberg equilibrium due to inbreeding. What is the expected effect on the genotype frequencies?
What is the condition required for the maintenance of Hardy-Weinberg equilibrium?
What is the condition required for the maintenance of Hardy-Weinberg equilibrium?
What is the application of the Hardy-Weinberg theorem in predicting the incidence of inherited disease?
What is the application of the Hardy-Weinberg theorem in predicting the incidence of inherited disease?
What is the genotype frequency of individuals affected by Retinitis Pigmentosa in Tristan da Cunha?
What is the genotype frequency of individuals affected by Retinitis Pigmentosa in Tristan da Cunha?
What is the allele frequency of the allele associated with Retinitis Pigmentosa in Tristan da Cunha?
What is the allele frequency of the allele associated with Retinitis Pigmentosa in Tristan da Cunha?
What is the effect of the bottleneck effect on the genetic variation of a population?
What is the effect of the bottleneck effect on the genetic variation of a population?
What is the probability of being a carrier of the allele associated with Retinitis Pigmentosa in Tristan da Cunha?
What is the probability of being a carrier of the allele associated with Retinitis Pigmentosa in Tristan da Cunha?
What is the expected genotype frequency of the AA genotype in a population at Hardy-Weinberg equilibrium, if the frequency of the A allele is 0.7?
What is the expected genotype frequency of the AA genotype in a population at Hardy-Weinberg equilibrium, if the frequency of the A allele is 0.7?
What is the expected allele frequency of the a allele in a population at Hardy-Weinberg equilibrium, if the frequency of the A allele is 0.6?
What is the expected allele frequency of the a allele in a population at Hardy-Weinberg equilibrium, if the frequency of the A allele is 0.6?
What is the consequence of a population not being in Hardy-Weinberg equilibrium at a particular genetic locus?
What is the consequence of a population not being in Hardy-Weinberg equilibrium at a particular genetic locus?
What is the purpose of the Hardy-Weinberg theorem in predicting the incidence of inherited disease?
What is the purpose of the Hardy-Weinberg theorem in predicting the incidence of inherited disease?
What is the likely consequence of a population experiencing a bottleneck effect?
What is the likely consequence of a population experiencing a bottleneck effect?
What is the term for the phenomenon where a few individual organisms colonise a new habitat?
What is the term for the phenomenon where a few individual organisms colonise a new habitat?
