Glomerular Diseases and Complications Quiz
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Questions and Answers

The following are features of Membrano-Proliferative GN except

  • Basement Membrane Spikes
  • Hypercellular Glomeruli
  • Thickened Basement Membranes
  • Presents as Nephrotic or Nephritic Syndrome (correct)
  • Accentuated Lobular Pattern
  • The most frequent outcome of Acute Diffuse Glomerulonephritis is

  • Complete Recovery on Conservative Therapy (correct)
  • Progression to Focal Segmental Glomerulosclerosis
  • Progression to Chronic Renal Failure
  • Progression to Acute Renal Failure
  • Progression to _Rapidly_ Progressive GN
  • Which of the following is a feature of Henoch-Schönlein Syndrome

  • Diffuse Thickening of Basement Membrane
  • Crescent Formation
  • Mesangial Deposition of IgA (correct)
  • Diffuse Cellularity of Glomeruli
  • Tram Track appearance of Basement Membrane
  • Which of the following does not cause Acute Diffuse Tubular Necrosis

    <p>Transfusion with Hepatitis B infected blood</p> Signup and view all the answers

    Which of the following is a cause of Surgically Treatable Hypertension

    <p>Fibromuscular Dysplasia of Renal Artery</p> Signup and view all the answers

    Which of the following can arise as a complication of using Ampicillin and is associated with Eosinophilia?

    <p>Interstitial Nephritis</p> Signup and view all the answers

    Causes of Nephrotic Syndrome include all of the following EXCEPT

    <p>Malaria</p> Signup and view all the answers

    The following are true about Primary Biliary Cirrhosis EXCEPT

    <p>Jaundice develops early in the course</p> Signup and view all the answers

    The most frequent Malignant Thyroid Tumor in the young is

    <p>Papillary Carcinoma</p> Signup and view all the answers

    Diabetic Microngiopathy can lead to all of the following EXCEPT

    <p>Myocardial Infarction</p> Signup and view all the answers

    Causes of Hypocalcemia include EXCEPT

    <p>None of the Above</p> Signup and view all the answers

    Which of the following will give rise to Lipiduria

    <p>Nephrotic Syndrome</p> Signup and view all the answers

    A 3 year old child with a solid 10cm Right Renal Mass is most likely having

    <p>Wilm's Tumor</p> Signup and view all the answers

    Which of the following is associated with Hyperplastic Arteriosclerosis and Fibrinoid Necrosis

    <p>Malignant Hypertension</p> Signup and view all the answers

    Which of the following Renal Changes is most likely to improve following a course of Corticosteroid Therapy

    <p>Patchy Tubular Necrosis</p> Signup and view all the answers

    Which of the following is a feature of Membranous Glomerulonephritis

    <p>Heavy Proteinuria</p> Signup and view all the answers

    Which of the following is a diagnostic feature of Rapidly Progressive Glomerulonephritis

    <p>Crescent Formation</p> Signup and view all the answers

    Which of the following is (are) a feature of Malignant Hypertension

    <p>A &amp; C</p> Signup and view all the answers

    Which of the following is not a feature of Diffuse Post Streptococcal Glomerulonephritis

    <p>Fusion of Podocyte Food Processes</p> Signup and view all the answers

    Low Serum Complement, Hypercellular Glomerulis and Subepithelial Immune Deposits are characteristically seen in

    <p>IgA Nephropathy</p> Signup and view all the answers

    Mesangial Deposits of IgA are characteristically seen in

    <p>IgA Nephropathy</p> Signup and view all the answers

    The expression Nodular Glomerulosclerosis is used to denote

    <p>A Pattern of Diabetic Glomerular Change</p> Signup and view all the answers

    Basement Membrane Spikes are characteristically seen in

    <p>Idiopathic Membranous GN</p> Signup and view all the answers

    Which Glomerular Disease is associated with C-ANCA

    <p>Type II RBGN</p> Signup and view all the answers

    Antiglomerular Basement Membrane Antibodies are characteristically seen in

    <p>Type I RBGN</p> Signup and view all the answers

    Which of the following is not a feature of Mesangial Cells

    <p>Metaplasia to Endothelial Cells</p> Signup and view all the answers

    Pyonephrosis is a known complication of

    <p>Acute Pyelonephritis</p> Signup and view all the answers

    Thyroidization is a feature of

    <p>Chronic Pyelonephritis</p> Signup and view all the answers

    Attenuation & Lamination of the Basement Membrane is seen in

    <p>Membrano-Proliferative GN</p> Signup and view all the answers

    Which of the following is associated with Fever, Purpuric Rash, Abdominal Colic & Proteinuria in children

    <p>Henoch-Schoen Lein Disease</p> Signup and view all the answers

    The following are features of the early stages of Ischemic Tubular Necrosis except

    <p>Hypotension</p> Signup and view all the answers

    Which of the following is associated with Hepatic Angiosarcoma

    <p>Benzene</p> Signup and view all the answers

    Asthma is most closely associated with

    <p>Hypertrophy of Mucus Glands</p> Signup and view all the answers

    A 3 month-old baby develops Azotemia following a Massive Gastroenteritis. Your most likely diagnosis is

    <p>Tubular Necrosis</p> Signup and view all the answers

    In the absence of smoking, Coal Worker Pneumoconiosis (CWP) does not predispose to

    <p>Pulmonary Tuberculosis</p> Signup and view all the answers

    The most prevalent Occupational Pneumoconiosis is

    <p>Silicosis</p> Signup and view all the answers

    The mechanism of cell and tissue injury in Silicosis is through

    <p>Inactivation of Cytochrome System</p> Signup and view all the answers

    Egg-Shell Calcification is characteristically seen in

    <p>Silicosis</p> Signup and view all the answers

    The following are true about Nasopharyngeal Carcinoma except

    <p>Radical Surgery is the standard treatment</p> Signup and view all the answers

    Which of the following is not a known risk for Carcinoma of the Larynx

    <p>Irradiation</p> Signup and view all the answers

    In Chronic Bronchitis, cigarettes smoking is not a factor in which of the following

    <p>Smooth Muscle Hyperplasia</p> Signup and view all the answers

    Bronchi in patients suffering from Chronic Bronchitis will most likely show

    <p>Both B &amp; C</p> Signup and view all the answers

    Which of the following is not a complication of Chronic Bronchitis

    <p>Pulmonary TB</p> Signup and view all the answers

    Microscopic Examination of Sputum from an Asthmatic will show

    <p>Both B &amp; C</p> Signup and view all the answers

    Following Myocardial Infarction due to Thrombosis in a Coronary Artery and management by Streptokinase (a thrombocytic agent), which of the following is likely to happen in myocardium

    <p>Apoptosis</p> Signup and view all the answers

    A 65 year old man has had Congestive Heart Failure for the past year. His Blood Pressure is 125/85 and is Afebrile. Chest X-Ray shows Left Ventricular Hypertrophy. Which of the following diseases is he most likely to have

    <p>Alcoholic Cardiomyopathy</p> Signup and view all the answers

    A 35 year old man who has Infective Endocarditis, which of the following laboratory findings is most likely to be present

    <p>Elevated Coxsackie B Viral Titer</p> Signup and view all the answers

    A Button-Hole Mitral Valve is most likely associated with

    <p>Rheumatic Heart Disease</p> Signup and view all the answers

    A 12 year old child who lives in a mud hut in Northeastern Brazil presents to the clinic in Congestive Heart Failure. On physical examination, she has Right Conjuctival Oedema, Preauricular Lymphadenopathy and Exophthalmos. The most likely etiology for these findings is

    <p>Chagas Disease</p> Signup and view all the answers

    A 44 year old previously healthy man had the sudden onset of Severe Dyspnea. A Chest X-Ray shows Pulmonary Atelectasis involving all of the Right Lung. This is most likely to have resulted from

    <p>Pulmonary Embolism</p> Signup and view all the answers

    A 5 week old baby was brought to the hospital because of difficulty of breathing and occasionally turning blue. There is a Pansystolic Murmer. Which of the following Congenital Cardiac Anomalies is most likely to be present

    <p>Ventricular Septal Defect</p> Signup and view all the answers

    Study Notes

    Membrano-Proliferative GN

    • Features EXCEPT basement membrane spikes
    • Most frequent outcome of Acute Diffuse Glomerulonephritis is complete recovery

    Henoch-Schoenlein Syndrome

    • Features include crescent formation, IgA deposition
    • Excludes diffuse thickening of basement membrane

    Acute Diffuse Tubular Necrosis

    • Not caused by post-partum hemorrhage
    • Excludes extensive burns, shock, sepsis, and transfusion with Hepatitis B

    Surgically Treatable Hypertension

    • Excludes IgA nephritis, diabetes mellitus, SLE nephritis, and Goodpasture syndrome
    • May be caused by fibromuscular dysplasia of the renal artery

    Ampicillin Complications

    • Interstitial nephritis is a possible complication
    • Post-streptococcal glomerulonephritis, IgA nephropathy, and acute tubular necrosis are excluded

    Nephrotic Syndrome Causes

    • Excludes malaria
    • Causes include diabetes, SLE, viral hepatitis, and post-streptococcal glomerulonephritis

    Primary Biliary Cirrhosis

    • Common in females, associated with pruritis, jaundice developing early, and increased alkaline phosphatase
    • Antimitochondrial antibodies are associated

    Malignant Thyroid Tumor

    • Most frequent in young patients is Papillary Carcinoma

    Diabetic Microangiopathy

    • Excludes Myocardial Infarction
    • Complications include retinopathy, nephropathy, and neuropathy

    Hypocalcemia Causes

    • Excludes granulomatous diseases, hypoparathyroidism, renal failure, and vitamin D deficiency.

    Lipiduria Causes

    • Ascending pyelonephritis, nephritic syndrome, and renal infarction are excluded

    Renal Mass

    • A 3-year-old child with a 10 cm right renal mass is likely to have Wilm's tumor.

    Hyperplastic Arteriosclerosis and Fibrinoid Necrosis

    • Associated with malignant hypertension and diabetes type II

    Renal Changes and Corticosteroid Therapy

    • Patchy tubular necrosis is unlikely to improve
    • Glomerular crescents, fusion of podocyte foot processes, hyperplastic arteriosclerosis are potential targets of improvement.

    Rapidly Progressive Glomerulonephritis (RPGN)

    • Diagnostic feature includes crescent formation.

    Malignant Hypertension

    • Features include hyperplastic arteriosclerosis and crescent formation.
    • Fibrinoid necrosis is also a feature.

    Diffuse Post-Streptococcal Glomerulonephritis

    • Features include hypertension, periorbital edema, granular casts in urine, and exclusion of fusion of podocyte foot processes.
    • Excludes immune complex deposition.
    • Features include hypertension and periorbital edema

    Low Complement, Hypercellular Glomeruli, Sub-epithelial Deposits

    • Characteristically seen in post-streptococcal glomerulonephritis (post-streptococcal GN).
    • Also applies to interstitial nephritis (minimal change disease)

    Mesangial Deposits of IgA

    • Characteristic of IgA Nephropathy

    Nodular Glomerulosclerosis

    • It represents a pattern of diabetic glomerular change, and is a manifestation of malignant hypertension
    • Exclusion of advanced pyelonephritis, thin membrane disease, crescent glomerulonephritis, and post-streptococcal GN.

    Type III Rapidly Progressive Glomerulonephritis (RBGN)

    • Associated with C-ANCA
    • Excludes type I RBGN, type II RBGN, IgA Nephropathy, Post-Streptococcal GN

    Antiglomerular Basement Membrane Antibodies

    • Characteristic of Type I and Type II RBGN

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    Renal Pathology Quiz PDF

    Description

    Test your knowledge on various glomerular diseases, their features, and outcomes. This quiz covers conditions such as Membranoproliferative GN, Henoch-Schoenlein Syndrome, and complications related to Ampicillin. Make sure to understand the exclusions and characteristics of each condition.

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