Questions and Answers
What does glomerulonephritis literally mean?
Inflammation of glomeruli
What is the hallmark of glomerular disease?
Proteinuria
Which type of antibody deposition is observed in small-vessel vasculitis?
No antibody deposition
What is the classification basis for glomerulonephritis?
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Which disease is NOT associated with inflammation of glomeruli?
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Study Notes
Glomerulonephritis
- "Glomerulonephritis" literally means inflammation of the glomeruli (glomerulo- meaning "relating to glomeruli" and -nephritis meaning "inflammation of the kidney")
Hallmark of Glomerular Disease
- The hallmark of glomerular disease is the presence of hematuria (blood in the urine) and/or proteinuria (excess protein in the urine)
Antibody Deposition in Small-Vessel Vasculitis
- In small-vessel vasculitis, the type of antibody deposition observed is granular or "lumpy-bumpy" pattern of Immunoglobulin G (IgG) and Complement 3 (C3) deposition
Classification of Glomerulonephritis
- Glomerulonephritis is classified based on the pathogenesis and histological features of the disease
Disease NOT Associated with Glomeruli Inflammation
- Diabetes mellitus is a disease NOT associated with inflammation of glomeruli
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