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What is the term used to describe the hereditary material that is passed down from one generation to the next?
What is the term used to describe the hereditary material that is passed down from one generation to the next?
Genetic material
In which part of the cell is the genetic material stored?
In which part of the cell is the genetic material stored?
The nucleus
Acetabularia is a genus of what type of organism?
Acetabularia is a genus of what type of organism?
Acetabularia is a multicellular organism.
Acetabularia is a multicellular organism.
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The nucleus of a cell controls the form of the cap in Acetabularia.
The nucleus of a cell controls the form of the cap in Acetabularia.
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What is the term used to describe a cell formed by the union of a sperm and an ovule?
What is the term used to describe a cell formed by the union of a sperm and an ovule?
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The zygote's nucleus is a combination of nuclei from both the sperm and the ovule.
The zygote's nucleus is a combination of nuclei from both the sperm and the ovule.
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What is the biological process by which a cell replicates its DNA and divides into two identical daughter cells?
What is the biological process by which a cell replicates its DNA and divides into two identical daughter cells?
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Which of the following is NOT a phase of mitosis?
Which of the following is NOT a phase of mitosis?
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What specific structure within the nucleus is responsible for the condensation of DNA into chromosomes during prophase?
What specific structure within the nucleus is responsible for the condensation of DNA into chromosomes during prophase?
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The spindle apparatus, which is involved in chromosome separation during mitosis, is present in both plant and animal cells.
The spindle apparatus, which is involved in chromosome separation during mitosis, is present in both plant and animal cells.
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Mitosis results in the formation of daughter cells that have half the number of chromosomes as the parent cell.
Mitosis results in the formation of daughter cells that have half the number of chromosomes as the parent cell.
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Name three of the basic components of DNA.
Name three of the basic components of DNA.
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Which of the following is a purine base found in DNA?
Which of the following is a purine base found in DNA?
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What type of bond holds the two strands of DNA together in a double helix?
What type of bond holds the two strands of DNA together in a double helix?
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The two strands of DNA run in the same direction (parallel).
The two strands of DNA run in the same direction (parallel).
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Which phase of the cell cycle is characterized by DNA replication?
Which phase of the cell cycle is characterized by DNA replication?
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Which of the following models of DNA replication was proven to be correct by the Meselson and Stahl experiment?
Which of the following models of DNA replication was proven to be correct by the Meselson and Stahl experiment?
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What is the basic unit of genetic information that determines inherited characteristics?
What is the basic unit of genetic information that determines inherited characteristics?
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What is the term for the complete set of genetic information in an organism?
What is the term for the complete set of genetic information in an organism?
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What are the storage units of genes?
What are the storage units of genes?
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Humans have 48 chromosomes.
Humans have 48 chromosomes.
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Which of the following is NOT a characteristic of a dominant allele?
Which of the following is NOT a characteristic of a dominant allele?
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A recessive allele is only expressed when it is paired with another recessive allele.
A recessive allele is only expressed when it is paired with another recessive allele.
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What is the term used to describe the genetic makeup of an individual?
What is the term used to describe the genetic makeup of an individual?
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What is the term used to describe the observable characteristics of an individual?
What is the term used to describe the observable characteristics of an individual?
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Study Notes
Locating and Nature of Genetic Information
- Genetic information is stored in the cell's nucleus.
- Genetic material is transmitted during reproduction, ensuring offspring have similar characteristics.
- Genetic material is also called hereditary material
Learning Outcomes
- Students should be able to identify where genetic material is stored.
- Students should be able to explain how genetic material is transferred.
- Students should understand the chemical makeup of genetic material.
Introduction
- Reproduction produces new generations of a species with similar traits.
- Hereditary characteristics are coded by a hereditary program, also known as genetic material.
- Microscopic organisms (like bacteria) reproduce while maintaining the same hereditary material.
Experiments on Unicellular Organisms: Acetabularia
- Acetabularia is a genus of green algae found predominantly in subtropical waters of Mediterranean and other warm seas.
- It's a single-celled organism composed of a foot, stalk, and cap.
- The nucleus is located in the foot, while the cap and stalk don't contain any nucleus.
- Two types of Acetabularia exist: mediterranea (smooth disc shaped cap) and crenulata (branched flower-like cap).
Cutting and Transplantation Nucleus Experiments (Hämmerling Experiments)
- Hämmerling cut Acetabularia species into two parts (one with the nucleus, one without).
- The part with the nucleus regenerated the entire organism, including the missing part.
- The part without the nucleus did not regenerate.
- This demonstrated that the nucleus controls cellular traits.
- A nucleus transplant experiment involving a species without a nucleus was transplanted with a nucleus from a genus of different character, and successfully produced a cap similar to the nucleus donor.
Experiments on Multicellular Organisms: Toad Transplant Experiment
- Toad experiments transplanted nuclei from a mature animal cell into an enucleated egg cell.
- The developed tadpoles showed traits corresponding to the donor nucleus.
- The nucleus determines the organism's traits.
Conclusion
- The nucleus is responsible for cell functions and individual traits.
- The nucleus houses genetic information, directing cell development.
Ultrastructure of Nuclei
- Plant cells have similar structures to animal cells, but with some differences.
- Animal cells and plant cells contain the same organelles (like mitochondria, ribosomes, etc), but plant cells have a cell wall, and vacuoles that are larger in size than the vacuoles of animal cells.
- The nucleus is a roughly spherical or irregular dense organelle with a nuclear membrane composed of two membranes with a space in between them (perinuclear space).
Mitosis
- Mitosis is cell division where a single cell divides into two identical daughter cells.
- Mitosis is important in cell growth, repair, and reproduction in many organisms, including plants.
- During mitosis the genomic DNA is duplicated and each set is segregated into each daughter cell, so that both daughter cells carry an identical chromosomal set.
- The phases of mitosis are prophase, metaphase, anaphase and telophase.
Cytokinesis
- Cytokinesis is the division of the cytoplasm during cell division.
- In animal cells, a cleavage furrow forms and pinches the cell in two.
- In plant cells, a cell plate forms to separate the two daughter cells, due to the presence of a cell wall.
Mitosis Definition
- Mitosis is a type of cell division where a cell divides into two identical daughter cells.
- Somatic cells undergo mitosis to grow and repair tissues.
- Somatic cells have the same number of chromosomes and the same genetic characteristics as the parent cell.
Griffith's Experiments
- Griffith studied Streptococcus pneumoniae bacteria affecting mice.
- Two strains existed: smooth (S), virulent, and rough (R), non-virulent.
- The S strain's capsule protected it from the hosts immune system, leading to death.
- When heat-killed S strain was injected alongside the R strain, the mice still died.
- This seemed to indicate that some component from the dead S strain transformed the harmless R strain into a deadly S strain.
Avery and Colleagues' Experiment
- Avery and colleagues investigated the transforming principle.
- They treated different DNA and proteins of the S strain with enzymes to determine which component was the transforming principle.
- Results showed only the removal of DNA prevented transformation.
- This showed DNA was the genetic component.
Relationship Between Chromosomes and DNA
- DNA contains vast information; so DNA molecules had to be packaged into the nucleus which has small size compared to the total length of the DNA molecules.
- DNA packaging involves histone proteins forming nucleosomes.
- The nucleosomes coil to form a tightly packed structure called the chromosome.
DNA Replication Concept
- DNA replication creates identical copies during cell division (specifically during S phase).
- This process is essential for inheritance.
Meselson-Stahl Experiment
- Meselson and Stahl studied DNA replication.
- They used isotopes to label DNA strands during replication.
- They found that DNA replication is semi-conservative (each new DNA molecule contains one original strand and one new strand).
Basic Concepts in Genetics
- Genes are basic units of genetic information.
- The genome is a complete set of an organism's genetic information.
- Chromosomes are structures that store genetic information (genes).
- DNA is a nucleic acid containing genetic instructions guiding all life forms.
Human Genome
- Most human cells have 46 chromosomes: 22 pairs of autosomes and 2 sex chromosomes (XY in males, XX in females)
Locus and Allele
- A locus is a specific location/point on a chromosome where a gene is located
- An allele is a variant from of a gene at a specific locus.
Dominant and Recessive Alleles
- A dominant allele is expressed when it is paired with a recessive allele.
- Recessive alleles are only expressed when paired with another recessive allele.
Genotype and Phenotype
- Genotype represents the genetic makeup of an organism (alleles present at each locus).
- Phenotype reflects the observable traits of an organism resulting from its genotype (expression of alleles). The observable traits can include color, weight, diseases, and other characteristics.
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Description
This quiz explores the nature and location of genetic information within cellular structures, including how it is transmitted during reproduction. Students will learn to identify genetic material, understand its chemical composition, and its role in heredity. Additionally, the quiz includes insights into unicellular organisms like Acetabularia and their hereditary processes.