Questions and Answers
What is the classification of enoxaparin (Lovenox)?
What is the action of enoxaparin?
Potentiates the inhibitory effect of antithrombin on factor Xa and thrombin.
Enoxaparin is contraindicated in: ______
Hypersensitivity, hypersensitivity to benzyl alcohol, positive in vitro test for antiplatelet antibody in the presence of enoxaparin, active major bleeding.
What precautions should be taken when using enoxaparin?
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Study Notes
Enoxaparin (Lovenox) Overview
- Classification:
- Therapeutic: anticoagulants
- Pharmacologic: antithrombotics
- Pregnancy Category: B, considered safe for use during pregnancy
Mechanism of Action
- Enhances the effect of antithrombin, leading to inhibition of factor Xa and thrombin.
- Therapeutic Effects: Primarily used to prevent thrombus (blood clot) formation, reducing the risk of venous thromboembolism and other clot-related issues.
Contraindications and Precautions
- Contraindications include:
- Hypersensitivity to enoxaparin or benzyl alcohol (found in multidose vials)
- Positive in vitro test for antiplatelet antibodies when enoxaparin is present
- Active major bleeding, which poses significant health risks
- Use cautiously in individuals with:
- Severe liver or kidney disease, as dosage may need adjustment based on creatinine clearance (CCr) levels
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Description
This quiz covers essential information about Enoxaparin (Lovenox), including its classification as an anticoagulant, its mechanism of action, therapeutic effects, contraindications, and precautions. Ideal for students and healthcare professionals, this quiz will enhance your understanding of this important medication.
