أسئلة المحاضرات (8 - 9 - 10) امبريولوجي (قبل التعديل)
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Questions and Answers

What does a urachal fistula indicate?

  • Absence of urachal structures
  • Development of abnormal urinary connections
  • Persistence of the distal part of the urachus
  • Persistence of the whole urachus (correct)

Which structure is primarily responsible for embryonic nutrition before placental function begins?

  • Allantois
  • Amniotic fluid
  • Umbilical cord
  • Yolk sac (correct)

Which of the following best describes the structure of the umbilical cord?

  • Covered with an amniotic sheath formed from extra-embryonic mesoderm (correct)
  • Covered by a thick fibrous layer with no underlying structures
  • Contains only the definitive yolk sac
  • Includes only two umbilical arteries

What physiological change occurs in the umbilical cord during the 6th to 10th week of development?

<p>Physiological hernia occurs (D)</p> Signup and view all the answers

What is the significance of cells migrating from the gut to the gonads?

<p>Formation of germ cells (B)</p> Signup and view all the answers

What does the left umbilical vein develop into after birth?

<p>Ligamentum teres of liver (B)</p> Signup and view all the answers

What type of umbilical cord attachment is characterized by being attached to the margin of the placenta?

<p>Marginal (B)</p> Signup and view all the answers

Which type of true knot in the umbilical cord affects placental circulation?

<p>True knot (D)</p> Signup and view all the answers

What structure does the chorion frondosum contribute to?

<p>Fetal part of the placenta (C)</p> Signup and view all the answers

Which type of villi is characterized by containing fetal blood vessels?

<p>Tertiary villi (A)</p> Signup and view all the answers

What is the fate of the chorion leave?

<p>Degenerates (C)</p> Signup and view all the answers

What can a long umbilical cord lead to during pregnancy?

<p>Formation of true knots (A)</p> Signup and view all the answers

Which anatomical structures are involved in the formation of primary villi?

<p>Syncytiotrophoblast and cytotrophoblast (C)</p> Signup and view all the answers

What is the main source of amniotic fluid in the amniotic cavity?

<p>Placenta (A), Fetal kidneys (B), Amnioblasts (D)</p> Signup and view all the answers

During which week does the amniotic cavity completely surround the embryo?

<p>4th week (C)</p> Signup and view all the answers

What characterizes oligohydramnios?

<p>Fluid less than 0.5 liters (A)</p> Signup and view all the answers

Which of the following is NOT a function of the amniotic cavity?

<p>Fuel fetal metabolism (D)</p> Signup and view all the answers

What is one cause of polyhydramnios?

<p>Diabetes in the mother (B)</p> Signup and view all the answers

What percentage of the amniotic fluid is composed of water?

<p>99% (B)</p> Signup and view all the answers

What is a potential consequence of prolonged oligohydramnios?

<p>Fetal adhesion and anomalies (A)</p> Signup and view all the answers

Which structure forms the roof of the amniotic cavity during its development?

<p>Amnioblasts (A), Somatic extra-embryonic mesoderm (C)</p> Signup and view all the answers

What is the weight of the placenta in relation to the baby?

<p>1/6 of baby weight (D)</p> Signup and view all the answers

Which structure forms the fetal part of the placenta?

<p>Chorion frondosum (C)</p> Signup and view all the answers

How does the placenta facilitate respiratory function for the fetus?

<p>Simple diffusion via the placental barrier (D)</p> Signup and view all the answers

What is a key characteristic of the maternal surface of the placenta?

<p>Cobblestone appearance (D)</p> Signup and view all the answers

At what week of pregnancy do changes in the placental barrier structure occur?

<p>After the 20th week (A)</p> Signup and view all the answers

Which hormone is secreted by the placenta to maintain the corpus luteum?

<p>Human chorionic gonadotropin (HCG) (D)</p> Signup and view all the answers

What condition is known as accessory placenta?

<p>Placenta succentriata (B)</p> Signup and view all the answers

Which function of the placenta involves the elimination of waste products from the fetus?

<p>Excretory function (C)</p> Signup and view all the answers

What is the function of the allantois in embryonic development?

<p>Extension from the yolk sac into the umbilical cord (A)</p> Signup and view all the answers

Which structure becomes incorporated inside the embryo during the 4th week?

<p>Yolk sac (D)</p> Signup and view all the answers

What happens to the extra-embryonic part of the allantois?

<p>It degenerates (A)</p> Signup and view all the answers

What is a common feature of Meckel’s diverticulum?

<p>Containing ectopic pancreatic tissue (B)</p> Signup and view all the answers

Which of the following options describes a vitelline cyst?

<p>Persistence of the middle part of the vitelline duct (C)</p> Signup and view all the answers

What can occur if the vitelline duct is obliterated but not degenerated?

<p>Vitelline band (B)</p> Signup and view all the answers

What marks the transition from the primary yolk sac to the second yolk sac?

<p>Communication through the neurenteric canal (D)</p> Signup and view all the answers

What does the distal part of the urachus become after its development?

<p>Median umbilical ligament (D)</p> Signup and view all the answers

What is a characteristic of placenta percreta?

<p>Chorionic villi penetrate into the surrounding organs (B)</p> Signup and view all the answers

Which type of twins arises from the fertilization of two separate eggs?

<p>Dizygotic twins (D)</p> Signup and view all the answers

What type of twin formation occurs at the bilaminar stage of development?

<p>Monoamniotic monochorionic (A)</p> Signup and view all the answers

Which of the following is not a characteristic of monozygotic twins?

<p>They are completely separate in appearance (C)</p> Signup and view all the answers

What is the primary cause of conjoined twins?

<p>Incomplete separation of the embryonic disc (C)</p> Signup and view all the answers

At which developmental stage do diamniotic dichorionic twins form?

<p>2 cell stage (B)</p> Signup and view all the answers

What percentage of twin births are typically dizygotic?

<p>70% (C)</p> Signup and view all the answers

Which of the following characteristics applies to dizygotic twins?

<p>Non-identical genetic makeup (B)</p> Signup and view all the answers

What is a primary cause of oligohydramnios?

<p>Renal agenesis (C)</p> Signup and view all the answers

Which component is primarily responsible for the maintenance of electrolyte balance in the amniotic cavity?

<p>Fetal kidney (A)</p> Signup and view all the answers

During which week of development does the amniotic cavity fully encapsulate the embryo?

<p>Fourth week (B)</p> Signup and view all the answers

What is the main composition of amniotic fluid?

<p>99% water (A)</p> Signup and view all the answers

What is a common fetal anomaly associated with oligohydramnios?

<p>Fetal adhesion (A)</p> Signup and view all the answers

What source primarily contributes to the production of amniotic fluid at later stages of fetal development?

<p>Fetal kidney (D)</p> Signup and view all the answers

What is the primary role of the yolk sac before the function of the liver begins?

<p>Nutritional provision to the embryo (B)</p> Signup and view all the answers

Which structure is formed from the allantois after birth?

<p>Median umbilical ligament (A)</p> Signup and view all the answers

What is the fate of the intra-embryonic part of the allantois?

<p>It forms the median umbilical ligament (A), It becomes the apex of the urinary bladder (C)</p> Signup and view all the answers

During which week does physiological hernia occur as a normal developmental change?

<p>6th to 10th week (C)</p> Signup and view all the answers

Which anomaly is characterized by the persistence of the whole vitelline duct?

<p>Vitelline fistula (D)</p> Signup and view all the answers

What is the correct description of the primitive umbilical cord's diameter?

<p>1 cm (B)</p> Signup and view all the answers

During which week does the second yolk sac begin to communicate with the amniotic cavity?

<p>Third week (A)</p> Signup and view all the answers

What contributes to the formation of Meckel’s diverticulum?

<p>Persistence of the proximal part of the vitelline duct (C)</p> Signup and view all the answers

What component is NOT part of the structure of the primitive umbilical cord?

<p>Amniotic fluid (C)</p> Signup and view all the answers

Which structure is formed from the medial part of the allantois?

<p>Median umbilical ligament (D)</p> Signup and view all the answers

What remains connected to the definitive yolk sac by the vitello-intestinal duct?

<p>Part of the yolk sac incorporated inside the baby (C)</p> Signup and view all the answers

In which population is Meckel’s diverticulum more prevalent?

<p>Males (C)</p> Signup and view all the answers

What defines the roof of the primary yolk sac?

<p>Hypoblast (A)</p> Signup and view all the answers

What is the primary reason for the occurrence of conjoined twins?

<p>Incomplete separation of the embryonic disc (C)</p> Signup and view all the answers

At which stage do diamniotic monochorionic twins develop?

<p>At the blastocyst stage (A)</p> Signup and view all the answers

Which type of twins is characterized by being genetically identical?

<p>Monozygotic (B)</p> Signup and view all the answers

What configuration characterizes placenta percreta?

<p>Chorionic villi penetrate myometrium and surrounding organs (D)</p> Signup and view all the answers

What percentage of twin births is typically attributed to dizygotic formation?

<p>70% (A)</p> Signup and view all the answers

Which statement about the appearance of monozygotic twins is true?

<p>They can share similar fingerprints (D)</p> Signup and view all the answers

What defines the fetal membranes configuration for diamniotic dichorionic twins?

<p>2 amnions, 2 chorions, and 2 placentas (A)</p> Signup and view all the answers

What is a potential site for fusion in conjoined twins?

<p>Cranial region (C)</p> Signup and view all the answers

What is the fate of the chorion frondosum during development?

<p>It forms the fetal part of the placenta. (C)</p> Signup and view all the answers

Which type of umbilical cord attachment is characterized by the cord being attached away from the placenta?

<p>Eccentric attachment (C)</p> Signup and view all the answers

What is a potential consequence of having a true knot in the umbilical cord?

<p>Loss of placental circulation, leading to fetal death (D)</p> Signup and view all the answers

What structure is primarily involved in the formation of tertiary villi?

<p>All listed structures including fetal blood vessels (D)</p> Signup and view all the answers

Which type of anomaly is characterized by a short umbilical cord?

<p>Causes fetal demise due to placental separation (A)</p> Signup and view all the answers

In the context of chorionic development, which type is destined to degenerate?

<p>Chorion leave (B)</p> Signup and view all the answers

How do absorbing villi function within the placenta?

<p>They exchange gases and materials between fetal and maternal blood. (C)</p> Signup and view all the answers

What results from the degeneration of the definitive yolk sac?

<p>It results in the loss of nutritional support for the embryo. (C)</p> Signup and view all the answers

What is the primary protective function of the placenta during pregnancy?

<p>To protect the fetus against maternal organisms (C)</p> Signup and view all the answers

Which surface of the placenta exhibits a characteristic cobblestone appearance?

<p>The maternal surface (A)</p> Signup and view all the answers

What happens to the structure of the placental barrier after the 20th week of pregnancy?

<p>It consists only of syncytiotrophoblast and fetal blood vessels (D)</p> Signup and view all the answers

Which hormone does the placenta primarily secrete to stimulate milk formation during pregnancy?

<p>Lactogen (D)</p> Signup and view all the answers

Which characteristic defines the weight of the placenta in relation to the baby's weight?

<p>It weighs approximately 1/6 of the baby weight (B)</p> Signup and view all the answers

What type of placenta anomaly is characterized by an accessory placenta?

<p>Placenta succentriata (B)</p> Signup and view all the answers

What is the main function of the placental barrier during fetal development?

<p>Separating maternal and fetal blood (C)</p> Signup and view all the answers

Which hormone is primarily responsible for maintaining the corpus luteum in early pregnancy?

<p>Human chorionic gonadotropin (HCG) (C)</p> Signup and view all the answers

What is the result of persistence of the entire urachus in embryonic development?

<p>Urachal fistula.</p> Signup and view all the answers

During which developmental week does the umbilical cord begin to take shape as a connecting stalk?

<p>During the 2nd week.</p> Signup and view all the answers

What are the two primary blood vessels found in a typical umbilical cord?

<p>Two umbilical arteries and one left umbilical vein.</p> Signup and view all the answers

What embryonic structure contributes to the formation of the median umbilical ligament after birth?

<p>Allantois.</p> Signup and view all the answers

What life-supporting function does the yolk sac provide before the liver takes over?

<p>Hematopoietic function for RBC formation.</p> Signup and view all the answers

What anatomical structure do the 2 umbilical arteries become after development?

<p>They become the medial umbilical ligaments.</p> Signup and view all the answers

What distinguishes a true knot from a false knot in the umbilical cord?

<p>A true knot affects placental circulation and can lead to fetal death, while a false knot does not.</p> Signup and view all the answers

During which stage are tertiary villi formed?

<p>Tertiary villi are formed when fetal blood vessels develop within them.</p> Signup and view all the answers

What condition is characterized by the persistent physiological hernia after the 10th week?

<p>Exomphalos or omphalocele.</p> Signup and view all the answers

What type of umbilical cord attachment is identified by being attached away from the placenta?

<p>This is known as a velamentous cord insertion.</p> Signup and view all the answers

What complications can arise from a short umbilical cord?

<p>It can lead to premature separation of the umbilical cord.</p> Signup and view all the answers

What are the primary components that make up primary villi?

<p>Primary villi are composed of syncytiotrophoblast and cytotrophoblast.</p> Signup and view all the answers

What are the different shapes of the placenta associated with placenta percreta?

<p>Zonary, Irregular, Bipartite, and Tripartite.</p> Signup and view all the answers

What is the genetic difference between dizygotic and monozygotic twins?

<p>Dizygotic twins are non-identical, whereas monozygotic twins are identical.</p> Signup and view all the answers

What is one of the key characteristics of conjoined twins?

<p>Twins may fuse at various body parts like the head or thorax.</p> Signup and view all the answers

How does the incidence of dizygotic twins compare to that of monozygotic twins?

<p>Dizygotic twins have a 70% incidence, while monozygotic twins have a 30% incidence.</p> Signup and view all the answers

How many zygotes are involved in the formation of dizygotic twins?

<p>Two zygotes.</p> Signup and view all the answers

Describe the process of amniotic fluid circulation in the amniotic cavity.

<p>Amniotic fluid is produced by amnioblasts and the placenta, is swallowed by the fetus, and excess fluid passes through the urinary system back into the cavity.</p> Signup and view all the answers

What are two potential causes of oligohydramnios?

<p>Placental insufficiency and renal agenesis are two potential causes.</p> Signup and view all the answers

Explain the significance of the amniotic cavity in fetal development.

<p>The amniotic cavity protects the fetus from trauma and infections, and allows for symmetrical growth and movement.</p> Signup and view all the answers

What is the maximum volume of amniotic fluid typically present at birth?

<p>The maximum volume of amniotic fluid at birth is approximately one liter.</p> Signup and view all the answers

Identify one fetal and one maternal cause of polyhydramnios.

<p>Esophageal atresia is a fetal cause, while diabetes is a maternal cause of polyhydramnios.</p> Signup and view all the answers

What characterizes the composition of amniotic fluid?

<p>Amniotic fluid is composed of 99% water and 1% organics, inorganic salts, and fetal epithelial cells.</p> Signup and view all the answers

What is one of the main developmental structures that form the floor of the amniotic cavity?

<p>The floor of the amniotic cavity is formed by epiblasts.</p> Signup and view all the answers

What effect does the rupture of the amniotic sac have during labor?

<p>Rupture of the amniotic sac allows the amniotic fluid to wash the vagina, facilitating vaginal birth.</p> Signup and view all the answers

What anatomical structures form the floor and roof of the primary yolk sac during embryonic development?

<p>The floor is formed by the hausser membrane and splanchnic extra-embryonic mesoderm, while the roof is formed by hypoblast.</p> Signup and view all the answers

Describe the fate of the intra-embryonic and extra-embryonic parts of the allantois.

<p>The extra-embryonic part degenerates, while the intra-embryonic part forms the urachus, which gives rise to the apex of the urinary bladder and the median umbilical ligament.</p> Signup and view all the answers

What anomalies are associated with the persistence of the vitelline duct?

<p>Anomalies include vitelline band, vitelline fistula, vitelline sinus, and vitelline cyst.</p> Signup and view all the answers

What structure is formed from the proximal part of the vitelline duct, and what percentage of people does it affect?

<p>Meckel’s diverticulum forms from the proximal part of the vitelline duct and occurs in about 2% of people.</p> Signup and view all the answers

In what manner does the second yolk sac communicate with the amniotic cavity?

<p>The second yolk sac communicates with the amniotic cavity through the neurenteric canal.</p> Signup and view all the answers

What key role does the definitive yolk sac play in embryonic development after folding occurs?

<p>Part of the yolk sac becomes incorporated inside the embryo to form gut, while another part remains outside as the definitive yolk sac.</p> Signup and view all the answers

What is the anatomical significance of the vitello-intestinal duct?

<p>The vitello-intestinal duct connects the yolk sac to the embryo and is critical for nutrient transfer during early development.</p> Signup and view all the answers

What occurs during the 4th week of embryonic development concerning the yolk sac?

<p>During the 4th week, part of the yolk sac is incorporated into the embryo to form the gut, while the rest remains as the definitive yolk sac linked by the vitello-intestinal duct.</p> Signup and view all the answers

What is the thickness and weight of the placenta as compared to the baby's weight?

<p>The placenta is approximately 2 cm thick and weighs about 1/6 of the baby's weight, which is around 0.5 kg.</p> Signup and view all the answers

Describe the appearance of the maternal surface of the placenta.

<p>The maternal surface of the placenta has a cobblestone appearance.</p> Signup and view all the answers

What structures form the placental barrier before the 20th week of pregnancy?

<p>Before the 20th week, the placental barrier consists of the syncytiotrophoblast, cytotrophoblast, extra-embryonic mesoderm, and fetal blood vessels.</p> Signup and view all the answers

What is the primary function of the placenta in terms of gas exchange for the fetus?

<p>The placenta facilitates gas exchange for the fetus through simple diffusion across the placental barrier.</p> Signup and view all the answers

Which hormones are secreted by the placenta to maintain pregnancy and support fetal development?

<p>The placenta secretes hormones such as human chorionic gonadotropin (HCG), progesterone, estrogen, lactogen, and relaxin.</p> Signup and view all the answers

What characterizes placenta previa as an anomaly?

<p>Placenta previa is characterized by the placenta's abnormal location over the cervix, which can lead to complications during delivery.</p> Signup and view all the answers

How does the thickness of the placenta change throughout pregnancy?

<p>The thickness of the placenta can vary but typically remains around 2 cm, particularly in the first and second trimesters.</p> Signup and view all the answers

Define placenta succenturiata and its significance.

<p>Placenta succenturiata refers to the presence of an accessory placenta, which can complicate delivery and increase risks of hemorrhage.</p> Signup and view all the answers

What forms the floor of the primary yolk sac during the second week of development?

<p>The floor is formed by the Hausser membrane and splanchnic extra-embryonic mesoderm.</p> Signup and view all the answers

How does the secondary yolk sac communicate with the amniotic cavity?

<p>It communicates through the neurenteric canal.</p> Signup and view all the answers

What are the features of Meckel's diverticulum?

<p>Meckel's diverticulum is present in 2% of people, occurs more commonly in males, is about two inches long, and is located two feet from the ileocecal junction.</p> Signup and view all the answers

What happens to the extra-embryonic portion of the allantois during development?

<p>The extra-embryonic part degenerates.</p> Signup and view all the answers

What structures remain connected by the vitello-intestinal duct?

<p>The part of the yolk sac incorporated inside the baby and the definitive yolk sac remain connected.</p> Signup and view all the answers

What anomaly occurs due to the persistence of the distal part of the urachus?

<p>A urachal sinus is formed.</p> Signup and view all the answers

What causes the formation of a vitelline fistula?

<p>A vitelline fistula forms due to the persistence of the entire vitelline duct.</p> Signup and view all the answers

What are the primary sources of amniotic fluid in the amniotic cavity?

<p>The primary sources are amnioblasts, the placenta, and the fetal kidneys.</p> Signup and view all the answers

How does excess amniotic fluid affect the fetus during development?

<p>Excess amniotic fluid can result in polyhydramnios, causing potential complications such as fetal anomalies and maternal discomfort.</p> Signup and view all the answers

During which week of development does the amniotic cavity begin to communicate with the yolk sac?

<p>The amniotic cavity communicates with the yolk sac during the 3rd week of development.</p> Signup and view all the answers

What are some of the key functions of the amniotic cavity?

<p>Key functions include preventing infection, protecting against trauma, and allowing free movement to prevent body adhesion.</p> Signup and view all the answers

What is oligohydramnios and what are its possible causes?

<p>Oligohydramnios is defined as having less than 0.5 liters of amniotic fluid, potentially caused by placental insufficiency, renal agenesis, or urinary tract obstruction.</p> Signup and view all the answers

What happens to the amniotic fluid when the fetus swallows it?

<p>When the fetus swallows amniotic fluid, excess water passes through the urinary system back into the amniotic cavity.</p> Signup and view all the answers

What is the characteristic composition of amniotic fluid at birth?

<p>At birth, amniotic fluid is composed of 99% water and 1% organic and inorganic materials.</p> Signup and view all the answers

What role does the amniotic fluid play during labor?

<p>During labor, the amniotic fluid helps in dilating the cervix and can wash the vagina upon rupture.</p> Signup and view all the answers

What is the clinical significance of a persistent urachal diverticulum?

<p>A persistent urachal diverticulum can lead to complications such as urinary tract infections or the formation of diverticulitis.</p> Signup and view all the answers

Describe the role of the yolk sac before the liver takes over hematopoiesis.

<p>The yolk sac is responsible for the formation of red blood cells during early embryonic development until the liver assumes this function.</p> Signup and view all the answers

What are the main components of the primitive umbilical cord?

<p>The primitive umbilical cord consists of a connecting stalk, umbilical vessels (two arteries and one vein), allantois, and Wharton’s jelly.</p> Signup and view all the answers

What anatomical changes occur in the umbilical cord structure during the 4th week of development?

<p>During the 4th week, the umbilical cord is carried from the caudal end to the ventral surface of the embryo as a result of body folding.</p> Signup and view all the answers

How does the allantois contribute to fetal development after birth?

<p>The allantois becomes the median umbilical ligament, which helps maintain the position of the urinary bladder.</p> Signup and view all the answers

What are the consequences of a true knot in the umbilical cord?

<p>A true knot can stop placental circulation, potentially causing fetal death.</p> Signup and view all the answers

Describe the role of anchoring villi in embryonic development.

<p>Anchoring villi fix the embryonic sac to the endometrium, providing stability for the developing embryo.</p> Signup and view all the answers

Explain the difference between chorion leave and chorion frondosum.

<p>Chorion leave is directed towards the decidua capsularis and degenerates, while chorion frondosum forms the fetal part of the placenta at the decidua basalis.</p> Signup and view all the answers

What happens to the umbilical vein after birth?

<p>The left umbilical vein becomes the ligamentum teres of the liver post-birth.</p> Signup and view all the answers

How can the length of the umbilical cord affect pregnancy outcomes?

<p>A long umbilical cord can lead to true knots formation, while a short cord may cause premature separation.</p> Signup and view all the answers

What are secondary villi, and what additional structure do they form?

<p>Secondary villi are formed from syncytiotrophoblast, cytotrophoblast, and somatic extra-embryonic mesoderm.</p> Signup and view all the answers

What is exomphalos, and when does it occur during development?

<p>Exomphalos, or omphalocele, is a persistent physiological hernia that occurs after the 10th week of gestation.</p> Signup and view all the answers

Identify the types of umbilical cord attachment and their characteristics.

<p>Eccentric attachment is away from the center, marginal is at the placental margin, and velamentous is further away from the placenta.</p> Signup and view all the answers

What is the characteristic shape of placenta percreta?

<p>The shape of placenta percreta can be zonary, irregular, bipartite, or tripartite.</p> Signup and view all the answers

What are the two types of twins based on their formation?

<p>The two types of twins are dizygotic and monozygotic.</p> Signup and view all the answers

What is the genetic characteristic of monozygotic twins?

<p>Monozygotic twins are genetically identical.</p> Signup and view all the answers

During which developmental stage do diamniotic dichorionic twins form?

<p>Diamniotic dichorionic twins form at the 2-cell stage.</p> Signup and view all the answers

What causes conjoined twins to occur?

<p>Conjoined twins arise due to the incomplete separation of the embryonic disc.</p> Signup and view all the answers

What is the incidence rate of dizygotic twins compared to monozygotic twins?

<p>Dizygotic twins have a 70% incidence rate, while monozygotic twins have a 30% incidence rate.</p> Signup and view all the answers

What are the different types of twin configurations during pregnancy?

<p>The configurations are diamniotic dichorionic, diamniotic monochorionic, and monoamniotic monochorionic.</p> Signup and view all the answers

Which type of twins may fuse at the dorsal surface?

<p>Conjoined twins may fuse at the dorsal surface.</p> Signup and view all the answers

What are the two main parts of the placenta and which structures form them?

<p>The fetal part is formed by the chorion frondosum, and the maternal part is formed by the decidua basalis.</p> Signup and view all the answers

Describe the shape and dimensions of the placenta.

<p>The placenta has a discoid shape, with a diameter of 20 cm and a thickness of 2 cm.</p> Signup and view all the answers

What is the placental barrier, and how does its structure change after the 20th week of pregnancy?

<p>The placental barrier is a membrane separating maternal and fetal blood; after the 20th week, it includes syncytiotrophoblast, extra-embryonic mesoderm, and fetal blood vessels.</p> Signup and view all the answers

What are the primary functions of the placenta?

<p>The placenta's main functions are protective, respiratory, excretory, nutritive, and secretory.</p> Signup and view all the answers

Which hormone secreted by the placenta is responsible for maintaining the corpus luteum during the first four months of pregnancy?

<p>Human chorionic gonadotropin (HCG) is responsible for maintaining the corpus luteum.</p> Signup and view all the answers

What is placenta previa, and how does it differ from a succenturiate placenta?

<p>Placenta previa occurs when the placenta covers the cervix, while a succenturiate placenta is characterized by an accessory placenta.</p> Signup and view all the answers

How does the placenta facilitate gas exchange for the fetus?

<p>The placenta facilitates gas exchange through simple diffusion across the placental barrier.</p> Signup and view all the answers

What is the normal weight of the placenta in relation to fetal weight?

<p>The placenta weighs approximately 1/6 of the baby's weight, or about 0.5 kg.</p> Signup and view all the answers

Flashcards

Amniotic Cavity

The fluid-filled space that surrounds the developing embryo.

Amniotic Fluid

The fluid inside the amniotic cavity that cushions and protects the developing fetus.

Amnioblasts

The cells that line the amniotic cavity and contribute to the production of amniotic fluid.

Oligohydramnios

A condition where there's too little amniotic fluid.

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Polyhydramnios

A condition where there's too much amniotic fluid.

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Fetal Kidneys

The main source of amniotic fluid after the first trimester.

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Fetal Adhesion

A condition that can occur when there's too little amniotic fluid, causing the fetus to be restricted in their movements and potentially leading to developmental problems.

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Rupture of Membranes

The process where the amniotic sac breaks and releases amniotic fluid, often signaling the start of labor.

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Primary Yolk Sac

The initial yolk sac forms during the second week of development. Its floor is made of the Hauser's membrane and splanchnic extra-embryonic mesoderm, while the roof is formed by the hypoblast.

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Secondary Yolk Sac

The second yolk sac appears in the third week of development and establishes a connection with the amniotic cavity through the neurenteric canal.

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Yolk Sac Incorporation

During the fourth week, the yolk sac becomes incorporated into the developing baby, forming the gut. A portion of the yolk sac remains outside the baby, becoming the definitive yolk sac.

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Vitelline Duct

The vitelline duct connects the yolk sac to the developing baby's gut during the fourth week. It typically disappears after birth.

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Vitelline Duct Anomalies

Anomalies related to the vitelline duct can occur due to incomplete closure or degeneration. These include:
-Vitelline Band
-Vitelline Fistula
-Vitelline Sinus
-Vitelline Cyst
-Meckel's Diverticulum

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Meckel's Diverticulum

Meckel's diverticulum is a common anomaly of the vitelline duct. It occurs in 2% of people and presents as a small pouch extending from the small intestine. It often occurs in males and can contain ectopic tissues.

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Allantois

The allantois is an extension of the yolk sac that extends into the umbilical cord.

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Allantois Fate

The allantois has two parts: the extraembryonic part, which degenerates, and the intraembryonic part called the urachus. The urachus contributes to the development of the urinary bladder and umbilical ligament.

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Urachal diverticulum

A congenital anomaly caused by the persistence of the proximal part of the urachus. It is basically a pouch that protrudes from the bladder.

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Urachal fistula

A congenital anomaly caused by the persistence of the entire urachus, which is a tube connecting the bladder to the umbilicus during fetal development.

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Umbilical cord

The structure connecting the fetus to the placenta, containing blood vessels and supporting tissues.

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Wharton's jelly

A gelatinous substance found within the umbilical cord, providing support and cushioning for the blood vessels.

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Physiological hernia

A physiological bulge that occurs during the 6th to 10th week of fetal development. It is caused by the intestines pushing against the abdominal wall.

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Eccentric Umbilical Cord Attachment

This condition occurs when the umbilical cord attaches to the placenta away from the center.

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Marginal Umbilical Cord Attachment

This is when the umbilical cord attaches to the edge of the placenta, like a ribbon tied to the side of a gift.

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Abnormal Umbilical Cord Number

An umbilical cord with one extra artery or vein (usually 2 arteries and 1 vein)

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Vilamentous Umbilical Cord Attachment

A cord with loose, thread-like vessels that are not attached to the placenta, which can cause complications.

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False Knot in the Umbilical Cord

This type of knot does not affect the blood flow in the umbilical cord.

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True Knot in the Umbilical Cord

A tight knot in the cord that blocks blood flow to the fetus, leading to potential death.

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Long Umbilical Cord

This condition involves the umbilical cord being longer than normal, increasing the risk of forming true knots.

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Short Umbilical Cord

This is when the umbilical cord is shorter than normal, potentially leading to premature separation of the cord from the placenta.

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Dizygotic Twins

A type of twin pregnancy where two separate fertilized eggs implant in the uterus.

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Monozygotic Twins

A type of twin pregnancy where one fertilized egg splits, resulting in two babies with identical DNA.

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Monoamniotic Monochorionic Twins

Twins that share a single placenta and amniotic sac. This occurs when the fertilized egg splits very late in development.

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Diamniotic Monochorionic Twins

Twins that share a single placenta but have separate amniotic sacs.

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Diamniotic Dichorionic Twins

Twins that have separate placentas and amniotic sacs.

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Conjoined Twins

Twins that are physically joined at birth, caused by incomplete separation of the embryonic disc.

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Placenta Percreta

A condition where the chorionic villi of the placenta penetrate the myometrium and may even reach other organs.

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Twins

The delivery of more than one embryo.

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Fetal Part of Placenta

The fetal component of the placenta, formed by the chorion frondosum, which contains fetal blood vessels and facilitates nutrient exchange.

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Maternal Part of Placenta

The maternal component of the placenta, formed by the decidua basalis, which provides a rich blood supply for the fetus.

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What is the placenta?

A disc-shaped organ that provides vital functions for the developing fetus throughout pregnancy.

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What is the Placental Barrier?

The placental barrier is a complex membrane that separates maternal and fetal blood, preventing direct mixing while allowing for exchange of substances.

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How Does the Placental Barrier Change During Pregnancy?

The placental barrier changes composition throughout pregnancy. Before 20 weeks, it's made of syncytiotrophoblast, cytotrophoblast, extra-embryonic mesoderm, and fetal blood vessels. After 20 weeks, the cytotrophoblast layer disappears, and by late pregnancy, only syncytiotrophoblast and fetal blood vessels remain.

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What is the Protective Function of the Placenta?

The placenta plays a crucial role in protecting the fetus against potential threats from the mother's immune system and environment.

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What is the Respiratory Function of the Placenta?

It allows for the exchange of oxygen and carbon dioxide between the mother and fetus through simple diffusion across the placental barrier.

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What is the Excretory Function of the Placenta?

The placenta allows the fetus to dispose of waste products, such as urea and uric acid, through simple diffusion across the placental barrier.

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What is the amniotic cavity?

The fluid-filled space that surrounds the developing embryo, formed by the epiblast floor and the amnioblast & somatic extra-embryonic mesoderm roof. It connects to the yolk sac during the third week.

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What is amniotic fluid?

The fluid inside the amniotic cavity, mainly composed of water (99%) and containing a small percentage of organic substances and inorganic salts. Its main source is the fetal kidney.

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What is rupture of membranes?

The process of the amniotic sac breaking, releasing amniotic fluid and usually signaling the beginning of labor.

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What is oligohydramnios?

A condition where there is too little amniotic fluid (less than 0.5 liters), usually caused by placental insufficiency, renal agenesis, or urinary tract obstruction.

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What is polyhydramnios?

A condition where there is too much amniotic fluid (more than 2 liters), often due to unknown causes (idiopathic). Other causes can be fetal issues like esophageal atresia or maternal conditions like diabetes.

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What are the main functions of amniotic fluid?

The main function of the amniotic fluid is to:

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What is rupture of membranes?

The process of the amniotic sac breaking, releasing amniotic fluid and usually signaling the beginning of labor.

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What is a premature rupture of membranes?

This situation occurs when the amniotic sac breaks, but the fluid doesn't flow out, a condition that can complicate the labor.

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What is the yolk sac?

The yolk sac is an important structure during embryonic development. It serves as a source of nutrition for the early embryo and plays a role in the formation of the gut.

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What is the vitelline duct?

The vitelline duct connects the yolk sac to the developing baby's gut. It normally disappears after birth, but failures in its development can lead to a number of anomalies.

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What is Meckel's diverticulum?

Meckel's diverticulum is a common anomaly of the vitelline duct, occurring in about 2% of people. It is a small pouch extending from the small intestine and can contain ectopic tissues.

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What is the allantois?

The allantois is an extension of the yolk sac that extends into the umbilical cord. It plays a role in the formation of the urinary bladder and umbilical ligament.

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What is the urachus?

The urachus is the intraembryonic part of the allantois. It contributes to the formation of the apex of the urinary bladder and the median umbilical ligament.

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What are urachal anomalies?

Urachal anomalies occur when the urachus doesn't close properly after birth. These can range from a small pouch to a persistent tube connecting the bladder to the belly button.

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What is a vitelline band?

Vitelline band is a remnant of the vitelline duct that persists and can cause problems like intestinal blockage or twisting.

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What is a vitelline fistula?

A vitelline fistula results from a complete failure of the vitelline duct to close, creating a direct connection from the small intestine to the outside of the abdomen.

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Yolk sac

Before the liver takes over, this structure produces red blood cells for the developing embryo.

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Primitive umbilical cord

The connecting stalk covered with amniotic sheath, filled with gelatinous material.

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What is the normal composition of the umbilical cord?

The umbilical cord normally contains two arteries carrying deoxygenated blood away from the fetus and one vein carrying oxygenated blood to the fetus.

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What happens to the umbilical cord after birth?

The umbilical arteries degenerate after birth and become ligaments, while the umbilical vein becomes the ligamentum teres of the liver.

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What are eccentric and marginal umbilical cord attachments?

An eccentric attachment occurs when the umbilical cord attaches to the placenta away from the center, while a marginal attachment positions it at the placental edge.

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What is the difference between false and true knots in the umbilical cord?

False knots are benign and don't affect placental circulation, but true knots can obstruct blood flow, potentially causing fetal death.

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What are the potential risks of a long or short umbilical cord?

A long cord can increase the risk of true knots forming, while a short cord can lead to premature separation from the placenta.

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What is exomphalus or omphalocele?

Exomphalus, or omphalocele, is a persistent physiological hernia occurring after the 10th week of gestation, meaning the intestines fail to retract into the abdomen.

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What are the different fates of chorion frondosum and chorion leave?

Chorion frondosum is the section of the chorion that faces the decidua basalis and contributes to forming the fetal part of the placenta, while chorion leave degenerates.

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What are the stages of chorion development?

The chorion develops through three stages: primary villi with syncytiotrophoblast and cytotrophoblast; secondary with the addition of extra-embryonic mesoderm; and finally tertiary with the inclusion of fetal blood vessels.

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What causes Conjoined Twins?

The incomplete separation of the embryonic disc leads to the development of conjoined twins.

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What causes Monozygotic Twins?

At the 2 cell stage, 4 cell stage, or blastocyst stage, differentiation of the cells is disrupted, leading to the formation of monozygotic twins.

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What are the parts of the placenta?

The fetal part is formed by the chorion frondosum, which is the outer layer of the placenta that connects to the fetus. The maternal part is formed by the decidua basalis, which is the lining of the uterus that is modified during pregnancy to support the placenta.

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What is the macroscopic structure of the placenta?

The placenta is shaped like a disc, about 20cm in diameter and 2cm thick. It typically weighs about 1/6th of the baby's weight.

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What are the surfaces of the placenta?

The maternal surface of the placenta has a rough, cobblestone appearance due to the presence of the decidua basalis. The fetal surface is smooth and is where the umbilical cord attaches.

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What is the primary yolk sac?

A structure that forms during the second week of development, with a floor made of epiblast and a roof made of amnioblasts and extra-embryonic mesoderm.

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What is the secondary yolk sac?

During the third week, this connects to the amniotic cavity through the neurenteric canal.

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What is yolk sac incorporation?

In the fourth week, the yolk sac becomes incorporated into the baby's developing gut.

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Urachus

The intraembryonic part of the allantois, contributing to the formation of the apex of the urinary bladder and the median umbilical ligament. Failure to close properly after birth can lead to various urinary tract anomalies.

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Exomphalus or Omphalocele

A persistent physiological hernia occurring after the 10th week of gestation, meaning the intestines fail to retract into the abdomen.

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Chorion frondosum

The section of the chorion that faces the decidua basalis and contributes to forming the fetal part of the placenta, while chorion leave degenerates.

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Umbilical Vessels

The umbilical vein carries oxygenated blood from the placenta to the fetus, while the umbilical arteries carry deoxygenated blood from the fetus to the placenta.

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Exomphalus (Omphalocele)

A persistent physiological hernia after the 10th week of gestation, where the intestines fail to retract into the abdomen.

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Chorion Laeve

The chorion facing the decidua capsularis, which degenerates during development.

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False Knot

A knot in the umbilical cord that doesn't affect placental circulation, often caused by the cord twisting.

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Describe the macroscopic structure of the placenta.

The placenta is a disc-shaped organ, about 20 centimeters in diameter and 2 centimeters thick. It typically weighs about 1/6th of the baby's weight.

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Macroscopic Structure of the Placenta

The placenta is a disc-shaped organ, about 20 centimeters in diameter and 2 centimeters thick. It typically weighs about 1/6th of the baby's weight.

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Amniotic fluid circulation

Amnioblasts and placenta produce fluid in the cavity while the fetus swallows and urinates, maintaining the balance.

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Yolk sac anomalies

Anomalies related to the yolk sac, which is a structure that provides nutrition for the early embryo.

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Placental Barrier

The membrane separating maternal & fetal blood, allowing for exchange of nutrients and waste while preventing direct mixing.

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Human Chorionic Gonadotropin (hCG)

Hormone produced by the placenta to maintain the corpus luteum, which produces progesterone during the first trimester.

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Progesterone

Hormone produced by the placenta after the fourth month of pregnancy that helps maintain the pregnancy.

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Estrogen

Hormone produced by the placenta during pregnancy that helps prepare the uterus for childbirth.

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Relaxin

Hormone produced by the placenta that relaxes ligaments and prepares the cervix for childbirth.

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Placenta Previa

A condition in which the placenta is implanted too low in the uterus, potentially blocking the birth canal.

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Study Notes

Fetal Membranes & Twins

  • Fetal membranes surround and protect the developing embryo/fetus, providing a protective environment and allowing for gas exchange, waste removal, and nutrition.
  • The amniotic cavity is filled with amniotic fluid, which cushions the embryo and prevents it from adhering to the membranes.
  • Amniotic fluid is mostly water, with a small percentage of organic and inorganic salts, and fetal epithelium.
  • Amniotic fluid originates in amnioblasts, the placenta, and the fetal kidney.
  • Excess amniotic fluid is absorbed back into the bloodstream, via the fetal kidneys, and waste products are removed by the maternal blood; fetus can also swallow some of the amniotic fluid.

Amniotic Fluid

  • Definition: Fluid that fills the amniotic cavity, surrounding the embryo.
  • Amount: Approximately one liter at birth.
  • Sources: Amnioblasts, placenta, and fetal kidneys.
  • Structure: Primarily water; also contains inorganic salts, organics, and fetal cells.
  • Circulation: Amniotic fluid is produced and absorbed by the fetus and placenta. Excess fluid is transported via the urinary system back to the amniotic cavity and waste products are returned to maternal blood; fetus can also swallow some of the fluid.

Oligohydramnios

  • Definition: Amniotic fluid volume less than 0.5 liters.
  • Causes: Placental insufficiency, renal agenesis, urinary tract obstruction.
  • Character: Fetal adhesions, other abnormalities.

Polyhydramnios

  • Definition: Amniotic fluid volume greater than 2 liters.
  • Causes: Idiopathic (most common), fetal issues (esophageal atresia), or maternal issues (diabetes).
  • Character: Maternal and fetal distress, possible true knots in the umbilical cord.

Yolk Sac

  • Definition: A cavity related to the ventral surface of the embryo.
  • Development: Formed during the second week, with a floor formed by the Heuser's membrane and a roof formed by the hypoblast. During the third week, it communicates with the amniotic cavity via the neurenteric canal. During the fourth week, some of the yolk sac is incorporated into the developing gut and some becomes the definitive yolk sac. Both are connected by the vitello-intestinal duct.

Vitelline Duct Anomalies

  • Vitelline band: The vitelline duct is obliterated but not completely degraded.
  • Vitelline fistula: Persistence of the entire vitelline duct.
  • Vitelline sinus: Persistence of the distal portion of the vitelline duct.
  • Vitelline cyst: Persistence of the middle portion of the vitelline duct.
  • Meckel’s diverticulum: Persistence of the proximal vitelline duct (occurs twice as commonly in males). It is approximately two inches long and is positioned a few feet from the ileocecal junction; it can have ectopic gastric or pancreatic tissue.

Allantois

  • Definition: Extension from the caudal part of the yolk sac into the umbilical cord.
  • Fate: Extra-embryonic part degenerates, while the intra-embryonic part becomes the urachus; the medial part forms the apex of the urinary bladder, and the distal part of the urachus forms the median umbilical ligament.
  • Anomalies: Persistence of the distal part (urachal sinus), middle part (urachal cyst), or the whole urachus (urachal fistula). A urachal diverticulum is the persistence of the proximal part of the urachus.

Umbilical Cord

  • Development: Forms during the second week as a connecting stalk and becomes positioned ventrally during the fourth week.
  • Structure: Primitive umbilical cord is ~50cm long and ~1cm in diameter and is composed of extra-embryonic mesoderm and the allantois. The umbilical cord contains umbilical vessels (2 arteries & 1 vein). Wharton's jelly surrounds the blood vessels.
  • Changes after birth: Allantois forms umbilical scar; two arteries are the left umbilical arteries; and the left umbilical vein is a ligament running to the liver.
  • Anomalies: Abnormal attachments to the placenta, number of vessels (2 or 3), and knots (true vs. false). Short or long cord and ectopic hernia (omphalocele). Variations in structure are possible.

Chorion

  • Structure: Syncytiotrophoblast, cytotrophoblast, and somatic extra-embryonic mesoderm.
  • Development: Primary villi develop from the syncytiotrophoblast and cytotrophoblast; Secondary villi develop by the addition of somatic extraembryonic mesoderm; tertiary villi have fetal blood vessels.
  • Types & Fate: Chorion leaves, chorion frondosum (fetal side of the placenta).
  • Function: Anchoring villi fix the embryonic sac to the endometrium; absorbing villi exchange gas and materials between the fetal and maternal blood.

Placenta

  • Parts: Fetal part (chorion frondosum) and maternal part (Decidua basalis).
  • Structure: Macroscopic structure is discoid, 20cm in diameter, 2cm thick and one-sixth of the fetal weight, with a cobblestone maternal surface and smooth fetal surface with umbilical cord.
  • Microscopic structure: Before 20th week, there are syncytiotrohpblast, cytotrophoblast & extra-embryonic mesoderm & fetal blood vessel. After 20th week, there are syncytiotrohpblast, extra-embryonic mesoderm & fetal blood vessel. Late in pregnancy, there are syncytiotrohpblast and fetal blood vessel.
  • Function: Gas exchange, nutrient transport, waste removal, and hormone secretion.

Placental anomalies

  • Placenta succentriata: Accessory placenta.
  • Placenta previa: Chorionic villi penetrate the myometrium of the uterine wall to surrounding organs.
  • Placenta percreta: The most severe form of the abnormal placenta previa in which the villi penetrate completely through the uterine wall, or endometrium (this is a more specific term).
  • Number anomalies: Abnormal number or abnormal placement of the placenta. Bipartite, zonary, irregular, or tripartite are terms used to describe variations in placental structure.

Twins

  • Definition: Delivery of more than one embryo.
  • Causes: Hereditary or medical (administration of exogenous gonadotropins).
  • Types: Dizygotic and monozygotic.
  • Dizygotic: Two oocytes are fertilized by two sperm- the two zygotes are viable and non-identical.
  • Monozygotic: One oocyte is fertilized by one sperm that splits to two zygotes. The zygotes are viable and genetically identical.
  • Conjoined Twins: Occur in monozygotic twins; the twins fuse at various stages of development and can fuse at the head, thorax, ventral surface or dorsal surface- this results in various degrees and locations of fusion.
  • Classification of monozygotic twins: Diamniotic-dichorionic, diamniotic-monochorionic, or monoamniotic-monochorionic, depending on the stage of separation.

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