8 Questions
Which molecule does eculizumab bind to with a very high affinity?
C5
What is required to work in conjunction with activated macrophages in the early stages of infection to kill infected endothelial cells (ECs)?
Helper T cells
In the chronological order of T cell responses, what comes after Recognition of the specific antigen?
Clonal Expansion (Proliferation)
What specifically results in the clonal expansion of T cells?
Interleukin 2 (IL-2)
Where are extracellular antigens processed and then presented to T cells?
Vesicles
What is the first signal when a T cell encounters an antigen?
T-cell receptor (TCR) recognition
Where must effector cytotoxic T lymphocytes (CTLs) migrate to carry out their functions?
Peripheral tissues at the site of infection
Do T cells interact with free or soluble antigens?
No, they do not.
Test your knowledge on eculizumab, C5 binding, immune response to Rickettsia, macrophages, T cell phases, and helper T cells. Learn about the mechanisms of action of eculizumab and the coordination between different immune cells during infection.
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