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Drugs Affecting the Endocrine System: Anterior Pituitary Hormones

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Drugs Affecting the Endocrine System: Anterior Pituitary Hormones

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Questions and Answers

What is the mechanism of action of growth hormone (GH)?

Directly binds to somatomedins I and II

Stimulates thyroid hormone release

Directly stimulates GH receptors in the hypothalamus

Mediated through somatomedins insulin-like growth factor I and II (correct)

Which hormone is used in the treatment of GH deficiency in children?

Growth hormone (somatotropin) (correct)

Gonadotropins

Gonadotropin-releasing hormone (GnRH)

Growth hormone inhibiting hormone (somatostatin)

What is the therapeutic use of somatostatin?

Treatment of delayed ovulation

Treatment of ovarian inactivity

Stimulate insulin production

Treatment of acromegaly (correct)

Which hormone stimulates the synthesis of follicle-stimulating hormone (FSH) and luteinizing hormone (LH)?

Gonadotropin-releasing hormone (GnRH) Signup and view all the answers

What is the action of follicle-stimulating hormone (FSH)?

Increase follicle size and development Signup and view all the answers

What is the therapeutic use of gonadotropins?

Induce ovulation and follicular growth Signup and view all the answers

What is the main responsibility of adrenocorticotropic hormone (ACTH)?

Stimulate the synthesis and release of pro opiomelanocortin Signup and view all the answers

Why are hormones of the anterior and posterior pituitary not administered orally?

They are susceptible to destruction by proteolytic enzymes Signup and view all the answers

When does the highest concentration of adrenocorticotropic hormone (ACTH) typically occur?

6 AM Signup and view all the answers

Which gland is the target of ACTH in its mechanism of action?

Adrenal cortex Signup and view all the answers

What effect does stress have on the secretion of ACTH?

Stimulates its secretion Signup and view all the answers

What is the primary therapeutic use of corticotrophin (ACTH)?

Differentiating between primary and secondary adrenal insufficiency Signup and view all the answers