12 Questions
What is the mechanism of action of growth hormone (GH)?
Mediated through somatomedins insulin-like growth factor I and II
Which hormone is used in the treatment of GH deficiency in children?
Growth hormone (somatotropin)
What is the therapeutic use of somatostatin?
Treatment of acromegaly
Which hormone stimulates the synthesis of follicle-stimulating hormone (FSH) and luteinizing hormone (LH)?
Gonadotropin-releasing hormone (GnRH)
What is the action of follicle-stimulating hormone (FSH)?
Increase follicle size and development
What is the therapeutic use of gonadotropins?
Induce ovulation and follicular growth
What is the main responsibility of adrenocorticotropic hormone (ACTH)?
Stimulate the synthesis and release of pro opiomelanocortin
Why are hormones of the anterior and posterior pituitary not administered orally?
They are susceptible to destruction by proteolytic enzymes
When does the highest concentration of adrenocorticotropic hormone (ACTH) typically occur?
6 AM
Which gland is the target of ACTH in its mechanism of action?
Adrenal cortex
What effect does stress have on the secretion of ACTH?
Stimulates its secretion
What is the primary therapeutic use of corticotrophin (ACTH)?
Differentiating between primary and secondary adrenal insufficiency
Explore the effects of drugs on the endocrine system, specifically focusing on the hormones secreted by the anterior pituitary. Learn about how these peptides bind to specific receptors and activate genes to promote protein synthesis and hormone release. Understand why these hormones are administered through methods like intramuscular and subcutaneous injections, or intranasally instead of orally.
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