Digestive System and Metabolism Overview
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Questions and Answers

What roles do carbohydrates play in cellular respiration?

Carbohydrates provide the primary source of energy through glycolysis and the Krebs cycle.

Explain the significance of essential amino acids in metabolism?

Essential amino acids are crucial as the body cannot synthesize them; they must be obtained from dietary protein.

How do minerals contribute to metabolic processes?

Minerals act as cofactors for enzymes, facilitating biochemical reactions essential for metabolism.

Describe the relationship between vitamins and coenzymes in metabolic reactions.

<p>Vitamins often function as coenzymes, enhancing the activity of enzymes in metabolic pathways.</p> Signup and view all the answers

What are the two main dietary sources of lipids?

<p>Lipids are primarily sourced from animal products (saturated fats) and plant sources like nuts and oils (unsaturated fats).</p> Signup and view all the answers

Identify two types of proteins and their significance in nutrition.

<p>Complete proteins, from animal sources, contain all essential amino acids, while incomplete proteins, found in legumes, lack some essential amino acids.</p> Signup and view all the answers

Why are fruits and vegetables essential for vitamin intake?

<p>Fruits and vegetables are rich in vitamins that serve as coenzymes, vital for various enzymatic reactions.</p> Signup and view all the answers

Which types of foods are highest in mineral content?

<p>Foods richest in minerals include vegetables, legumes, milk, and certain meats.</p> Signup and view all the answers

How do amino acids contribute to ATP formation in the absence of other fuel sources?

<p>Amino acids are oxidized to form ATP mainly when glucose and fats are not available.</p> Signup and view all the answers

What role does the liver play in detoxifying ammonia from amino acid metabolism?

<p>The liver detoxifies ammonia by combining it with carbon dioxide to form urea.</p> Signup and view all the answers

Describe the difference between functional and structural proteins.

<p>Functional proteins include enzymes and antibodies, while structural proteins consist of connective tissue fibers and muscle proteins.</p> Signup and view all the answers

In what circumstances are amino acids primarily used for ATP formation?

<p>Amino acids are primarily used for ATP formation when other fuel sources, like glucose and fats, are insufficient.</p> Signup and view all the answers

What are the main components formed during the digestion of proteins?

<p>Proteins are digested into amino acids through gastrointestinal digestion.</p> Signup and view all the answers

Identify a primary function of fats in the body.

<p>Fats provide insulation and cushion to protect body organs.</p> Signup and view all the answers

What is the consequence of inadequate availability of essential amino acids?

<p>Inadequate essential amino acids can lead to decreased protein synthesis, affecting normal bodily functions.</p> Signup and view all the answers

How does the body conserve proteins?

<p>Proteins are carefully conserved by body cells to maintain structural and functional integrity.</p> Signup and view all the answers

What role do resident bacteria play in the large intestine during nutrient absorption?

<p>Resident bacteria in the large intestine help digest remaining nutrients and produce vitamin K and some B vitamins.</p> Signup and view all the answers

Describe the process that occurs when feces enter the rectum.

<p>The presence of feces in the rectum triggers a defecation reflex, relaxing the internal anal sphincter.</p> Signup and view all the answers

How is the energy value of food measured, and what is its significance in metabolism?

<p>The energy value of food is measured in kilocalories (kcal) or Calories (C), which represent the metabolic fuel for ATP production.</p> Signup and view all the answers

List the major nutrients essential for body maintenance and their roles.

<p>The major nutrients are carbohydrates, lipids, proteins, and water; they are crucial for growth, maintenance, and repair of body tissues.</p> Signup and view all the answers

What frequency and nature of movements occur in the large intestine to propel food residues?

<p>The large intestine exhibits sluggish peristalsis along with frequent haustral contractions and slow, powerful mass movements occurring three to four times daily.</p> Signup and view all the answers

Explain the role of minerals in the body, particularly in enzymatic functions.

<p>Minerals serve as essential cofactors for enzymes, aiding in various biochemical reactions necessary for metabolism.</p> Signup and view all the answers

Discuss the relationship between vitamins and coenzymes in metabolism.

<p>Vitamins serve as precursors to coenzymes, which are necessary for the proper functioning of enzymes involved in metabolic pathways.</p> Signup and view all the answers

What is the significance of a balanced diet from the five food groups?

<p>A balanced diet from the five food groups ensures adequate intake of all necessary nutrients for optimal health.</p> Signup and view all the answers

What are the two intrinsic nerve plexuses found in the alimentary canal wall?

<p>Submucosal nerve plexus and Myenteric nerve plexus.</p> Signup and view all the answers

Where does food enter the stomach from the esophagus?

<p>Food enters the stomach at the cardioesophageal sphincter.</p> Signup and view all the answers

What is the shape and location of the stomach in the abdominal cavity?

<p>The stomach is C-shaped and located on the left side of the abdominal cavity.</p> Signup and view all the answers

What is the role of the pyloric sphincter in the digestive process?

<p>The pyloric sphincter regulates the emptying of food from the stomach into the small intestine.</p> Signup and view all the answers

What structures comprise the peritoneal cavity and its associated ligaments?

<p>The peritoneal cavity consists of structures such as the visceral peritoneum, parietal peritoneum, and ligaments like the falciform ligament.</p> Signup and view all the answers

Identify two key functions of the peritoneum in the abdominal cavity.

<p>The peritoneum supports abdominal organs and provides a friction-reducing surface for organ movement.</p> Signup and view all the answers

How does the diaphragm function in relation to the abdominal cavity?

<p>The diaphragm separates the thoracic cavity from the abdominal cavity and plays a key role in respiration.</p> Signup and view all the answers

What is the function of the greater omentum within the abdominal cavity?

<p>The greater omentum serves to insulate and protect the abdominal organs, as well as store fat.</p> Signup and view all the answers

What is the primary purpose of teeth in the human digestive system?

<p>Teeth masticate (chew) food into smaller fragments.</p> Signup and view all the answers

At what age do humans typically have a full set of 20 deciduous teeth?

<p>By age 2.</p> Signup and view all the answers

What are the four types of permanent teeth and their respective functions?

<p>Incisors (cutting), canines (tearing), premolars (grinding), molars (grinding).</p> Signup and view all the answers

What major change occurs in a person's teeth between the ages of 6 and 12?

<p>Deciduous teeth are replaced by permanent teeth.</p> Signup and view all the answers

Which teeth are typically the first to appear in infants?

<p>Lower central incisors.</p> Signup and view all the answers

What are the two major regions of a tooth?

<p>Crown and root.</p> Signup and view all the answers

How many total teeth make up a full set of permanent teeth in adults?

<p>32 teeth, including the wisdom teeth.</p> Signup and view all the answers

What is the primary function of molars in the human dentition?

<p>Grinding food.</p> Signup and view all the answers

What is the function of the pylorus in the stomach?

<p>The pylorus acts as a funnel-shaped terminal end that regulates the passage of partially digested food into the duodenum.</p> Signup and view all the answers

How does the stomach's ability to stretch benefit digestion?

<p>The stomach can stretch to hold about 4 liters (1 gallon) of food, facilitating the storage and gradual processing of food during digestion.</p> Signup and view all the answers

Describe the difference between the greater and lesser curvature of the stomach.

<p>The greater curvature is the convex lateral surface, while the lesser curvature is the concave medial surface of the stomach.</p> Signup and view all the answers

What role do rugae play in the stomach's function?

<p>Rugae are internal mucosal folds that allow the stomach to expand when full and increase its surface area for digestion.</p> Signup and view all the answers

Explain the significance of the lesser and greater omentum in the abdominal cavity.

<p>The lesser omentum connects the liver to the lesser curvature of the stomach, while the greater omentum extends over the abdominal organs for protection and insulation.</p> Signup and view all the answers

What are the primary regions of the stomach and their locations?

<p>The primary regions of the stomach include the cardial region near the heart, the fundus lateral to the cardiac region, the body as the midportion, and the pylorus as the terminal end.</p> Signup and view all the answers

How do the muscular layers of the stomach contribute to its function?

<p>The stomach contains longitudinal, circular, and oblique muscular layers that facilitate churning and mixing of food, aiding in mechanical digestion.</p> Signup and view all the answers

Why is the stomach considered an essential component of the digestive system?

<p>The stomach plays a crucial role in breaking down food both mechanically and chemically, preparing it for absorption in the small intestine.</p> Signup and view all the answers

What are the two protein-digestion enzymes secreted in the stomach?

<p>Pepsin and rennin.</p> Signup and view all the answers

How do peristalsis and retropulsion differentiate in their roles in the stomach?

<p>Peristalsis moves food toward the pylorus, while retropulsion forces food back into the stomach.</p> Signup and view all the answers

What is the primary function of the pyloric sphincter?

<p>To regulate the passage of chyme into the small intestine.</p> Signup and view all the answers

What substances are primarily absorbed in the stomach?

<p>Alcohol and aspirin.</p> Signup and view all the answers

What enzymatic actions occur at the brush border in the small intestine?

<p>Breakdown of double sugars into simple sugars and completion of protein digestion.</p> Signup and view all the answers

Describe the flow of chyme as it moves from the stomach to the small intestine.

<p>Chyme is gradually pushed through the pyloric sphincter into the duodenum.</p> Signup and view all the answers

What role does grinding play in the stomach's activities?

<p>Grinding vigorously mixes food and prepares it for further digestion.</p> Signup and view all the answers

How long does it typically take for the stomach to empty its contents?

<p>About 4 to 6 hours.</p> Signup and view all the answers

What are the primary contents of feces produced in the large intestine?

<p>Feces primarily contains undigested food residues, mucus, bacteria, and water.</p> Signup and view all the answers

Explain the role of resident bacteria in the large intestine.

<p>Resident bacteria digest remaining nutrients, produce some vitamin K and B vitamins, and release gases.</p> Signup and view all the answers

Describe the process that triggers defecation.

<p>Defecation is triggered by the presence of feces in the rectum causing the internal anal sphincter to relax, followed by the relaxation of the voluntary external anal sphincter.</p> Signup and view all the answers

What distinguishes haustral contractions from mass movements in the large intestine?

<p>Haustral contractions are frequent, sluggish movements, while mass movements are powerful contractions occurring three to four times per day.</p> Signup and view all the answers

How does the body obtain chemical energy from food?

<p>The body oxidizes food to transform it into adenosine triphosphate (ATP), which is the chemical energy driving cellular activities.</p> Signup and view all the answers

List the major nutrients required by the body for maintenance.

<p>The major nutrients are carbohydrates, lipids, proteins, and water.</p> Signup and view all the answers

What is the significance of consuming a balanced diet from the five food groups?

<p>A balanced diet ensures adequate amounts of all needed nutrients for proper body function and health maintenance.</p> Signup and view all the answers

What functions do kilocalories serve in relation to food?

<p>Kilocalories measure the energy value of food, indicating how much energy that food provides to the body.</p> Signup and view all the answers

What are the main components produced during the metabolism of proteins?

<p>Amino acids and urea are the main components produced during protein metabolism.</p> Signup and view all the answers

How do fats contribute to the protection of body organs?

<p>Fats provide cushioning to protect body organs from physical impact.</p> Signup and view all the answers

In what way does the liver contribute to the detoxification process during protein metabolism?

<p>The liver combines ammonia with carbon dioxide to form urea, detoxifying ammonia.</p> Signup and view all the answers

What happens to amino acids when other fuel sources are not available?

<p>Amino acids are oxidized to form ATP for energy when other sources are lacking.</p> Signup and view all the answers

Identify the two main types of proteins and their roles in the body.

<p>Functional proteins (like enzymes and antibodies) and structural proteins (like muscle proteins).</p> Signup and view all the answers

What is the significance of myelin sheaths related to fats?

<p>Myelin sheaths are built from fats and serve to insulate nerve fibers for optimal signal transmission.</p> Signup and view all the answers

Describe how ammonia is processed during amino acid catabolism.

<p>Ammonia is detoxified in the liver, where it is converted to urea.</p> Signup and view all the answers

What role do amino acids play in the formation of ATP?

<p>Amino acids can be oxidized to produce ATP when carbohydrates and fats are insufficient.</p> Signup and view all the answers

What is the main purpose of incisors in human dentition?

<p>Incisors are primarily used for cutting food.</p> Signup and view all the answers

Describe the primary difference between deciduous and permanent teeth.

<p>Deciduous teeth are temporary and replaced by permanent teeth, which are meant to last a lifetime.</p> Signup and view all the answers

At what ages do permanent molars typically begin to emerge?

<p>Permanent molars generally begin to emerge between the ages of 6 and 13.</p> Signup and view all the answers

What is the function of canines in the human mouth?

<p>Canines are used for tearing and piercing food.</p> Signup and view all the answers

List the two major regions of a tooth.

<p>The two major regions of a tooth are the crown and the root.</p> Signup and view all the answers

How many teeth are classified as molars in a full set of human permanent teeth?

<p>In a full set of permanent teeth, there are 12 molars.</p> Signup and view all the answers

Why are premolars also known as bicuspids?

<p>Premolars are called bicuspids because they typically have two cusps that aid in grinding food.</p> Signup and view all the answers

What is the typical number of teeth a child has by the age of two?

<p>By the age of two, a child typically has 20 deciduous teeth.</p> Signup and view all the answers

What two hormones stimulate pancreatic juice secretion and bile contractions?

<p>CCK and secretin.</p> Signup and view all the answers

How are most substances absorbed in the small intestine?

<p>By active transport through cell membranes.</p> Signup and view all the answers

What movement in the small intestine aids in mixing chyme with digestive juices?

<p>Segmental movements.</p> Signup and view all the answers

What is the primary role of peristalsis in the digestive system?

<p>To propel food through the digestive tract.</p> Signup and view all the answers

Through which vein are absorbed substances transported to the liver?

<p>The hepatic portal vein.</p> Signup and view all the answers

In the process of digestion, what type of transport do lipids use for absorption?

<p>Diffusion.</p> Signup and view all the answers

What is the significance of water absorption along the length of the small intestine?

<p>It helps maintain hydration and nutrient concentration for absorption.</p> Signup and view all the answers

What specific action does CCK have once it reaches the pancreas?

<p>It induces the secretion of enzyme-rich pancreatic juice.</p> Signup and view all the answers

What are the primary components absorbed into the capillary blood in the villi of the small intestine?

<p>Glycerol and short-chain fatty acids.</p> Signup and view all the answers

How are the end products of digestion transported to the liver?

<p>They are transported via the hepatic portal vein.</p> Signup and view all the answers

What is the role of mucosal cells in nutrient absorption?

<p>Mucosal cells allow food to enter them before transferring it into blood or lymph capillaries.</p> Signup and view all the answers

Explain the phenomenon of defecation.

<p>Defecation is the elimination of indigestible substances from the GI tract as feces.</p> Signup and view all the answers

Describe the process of absorption in the digestive system.

<p>Absorption involves the transfer of digested nutrients into the bloodstream or lymphatic system.</p> Signup and view all the answers

What is the primary role of saliva in the breakdown of food in the mouth?

<p>Saliva aids in lubricating food and contains salivary amylase, which initiates the digestion of starch.</p> Signup and view all the answers

What role does the small intestine play in nutrient absorption?

<p>The small intestine is where most nutrient absorption occurs due to its villi and microvilli.</p> Signup and view all the answers

What is meant by the term 'segmentation' in the context of digestive processes?

<p>Segmentation refers to the rhythmic contractions that mix food in the small intestine.</p> Signup and view all the answers

Describe the buccal phase of swallowing.

<p>The buccal phase is voluntary, occurring in the mouth where food is formed into a bolus and pushed into the pharynx by the tongue.</p> Signup and view all the answers

Identify the main reasons for the mechanical breakdown of food in the digestive system.

<p>Mechanical breakdown facilitates digestion and increases the surface area for enzymatic action.</p> Signup and view all the answers

What happens during the pharyngeal-esophageal phase of swallowing?

<p>This involuntary phase transports the bolus through the pharynx and esophagus to the stomach via peristalsis.</p> Signup and view all the answers

How does water play a role in the large intestine?

<p>Water is primarily absorbed in the large intestine, contributing to stool formation.</p> Signup and view all the answers

What is the significance of the cardioesophageal sphincter during swallowing?

<p>The cardioesophageal sphincter opens when food presses against it, allowing the bolus to enter the stomach.</p> Signup and view all the answers

How does chewing contribute to digestion in the mouth?

<p>Chewing physically breaks down food into smaller pieces, increasing the surface area for enzymes to act upon.</p> Signup and view all the answers

Explain why absorption does not occur in the mouth.

<p>Absorption does not occur in the mouth because its primary functions are ingestion and mechanical breakdown of food, rather than nutrient uptake.</p> Signup and view all the answers

What are the responses of the body during the swallowing process?

<p>The body blocks the nasal passages and respiratory pathways to ensure safe swallowing and prevent aspiration.</p> Signup and view all the answers

Identify the triggers for saliva release during the chewing process.

<p>Saliva is released in response to mechanical pressure of chewing and psychic stimuli such as the sight or smell of food.</p> Signup and view all the answers

What is the role of the upper esophageal sphincter during swallowing?

<p>It prevents air from entering the esophagus and keeps food from entering the trachea.</p> Signup and view all the answers

How does gastrin influence stomach activity?

<p>Gastrin triggers the production of protein-digesting enzymes, mucus, and hydrochloric acid in the stomach.</p> Signup and view all the answers

What triggers the activation of pepsinogen into pepsin?

<p>Pepsinogen is activated into pepsin by the acidic pH created by hydrochloric acid in the stomach.</p> Signup and view all the answers

What is the function of hydrochloric acid in the stomach?

<p>Hydrochloric acid creates an acidic environment essential for activating digestive enzymes and killing harmful microorganisms.</p> Signup and view all the answers

Describe the role of the epiglottis during swallowing.

<p>The epiglottis covers the glottis to prevent food from entering the trachea and directs it into the esophagus.</p> Signup and view all the answers

What occurs at the cardioesophageal sphincter during digestion?

<p>The cardioesophageal sphincter relaxes to allow the bolus of food to enter the stomach from the esophagus.</p> Signup and view all the answers

How does the pH of stomach contents change with food presence?

<p>The presence of food raises the pH, leading to the release of gastrin, which then decreases the pH through acid production.</p> Signup and view all the answers

What is the significance of a hostile environment in the stomach?

<p>A hostile environment in the stomach helps activate digestive enzymes and inhibits the growth of harmful microorganisms.</p> Signup and view all the answers

What defines the difference between LDLs and HDLs in cholesterol transport?

<p>LDLs transport cholesterol to body cells and are considered 'bad' due to atherosclerosis risk, while HDLs carry cholesterol from cells to the liver for breakdown and are deemed 'good.'</p> Signup and view all the answers

How does energy balance affect body weight stability?

<p>Body weight remains stable when energy intake equals energy output, ensuring no excess energy is stored.</p> Signup and view all the answers

What is the energy yield of fats compared to carbohydrates and proteins?

<p>Fats yield 9 kcal/gram, while carbohydrates and proteins yield 4 kcal/gram each.</p> Signup and view all the answers

Identify two factors that may regulate food intake in the body.

<p>The levels of nutrients in the blood and certain hormones can regulate food intake.</p> Signup and view all the answers

What are the consequences of interference with the body’s energy balance?

<p>Interference can lead to obesity and malnutrition, causing various health issues.</p> Signup and view all the answers

How is energy produced in the body during metabolism?

<p>Energy is produced during glycolysis, the citric acid cycle, and the electron transport chain.</p> Signup and view all the answers

What role do lipoproteins play in cholesterol transport?

<p>Lipoproteins, like LDLs and HDLs, facilitate the transport of cholesterol since it cannot circulate freely in the bloodstream.</p> Signup and view all the answers

Why are LDLs referred to as 'bad lipoproteins'?

<p>LDLs are termed 'bad' because their accumulation can lead to atherosclerosis, increasing cardiovascular disease risk.</p> Signup and view all the answers

What is the dual role of the pancreas in digestion and metabolism?

<p>The pancreas produces digestive enzymes that break down food and secretes hormones like insulin and glucagon that regulate blood sugar levels.</p> Signup and view all the answers

How does the pancreas neutralize acidic chyme in the duodenum?

<p>The pancreas secretes alkaline fluid along with digestive enzymes to neutralize the acidic chyme that enters the duodenum from the stomach.</p> Signup and view all the answers

List the two primary hormones produced by the pancreas and their functions.

<p>The two primary hormones are insulin, which lowers blood sugar levels, and glucagon, which raises blood sugar levels.</p> Signup and view all the answers

Explain the significance of the pancreas in the digestive process?

<p>The pancreas is significant because it produces a wide range of digestive enzymes that are essential for breaking down carbohydrates, proteins, and fats.</p> Signup and view all the answers

Where is the pancreas located, and what is its anatomical structure?

<p>The pancreas is located on the right side of the body under the diaphragm, consisting of four lobes held by the falciform ligament.</p> Signup and view all the answers

What is the primary function of the falciform ligament in relation to the liver?

<p>The falciform ligament anchors the liver to the anterior abdominal wall and the diaphragm.</p> Signup and view all the answers

Describe the location and significance of the greater omentum in the abdominal cavity.

<p>The greater omentum hangs down from the greater curvature of the stomach and extends to cover the intestines, providing insulation and immune defense.</p> Signup and view all the answers

How do the mesenteries contribute to the stability of the small intestine?

<p>Mesenteries support the small intestine by anchoring it to the posterior abdominal wall and containing blood vessels and nerves.</p> Signup and view all the answers

What is the function of the visceral peritoneum in relation to abdominal organs?

<p>The visceral peritoneum covers and protects the abdominal organs while facilitating movement within the abdominal cavity.</p> Signup and view all the answers

Explain the relationship between the diaphragm and the abdominal cavity during respiration.

<p>The diaphragm contracts and flattens during inhalation, increasing the thoracic cavity's volume and helping to draw air into the lungs while also impacting abdominal pressure.</p> Signup and view all the answers

What are the two primary nerve plexuses found in the wall of the alimentary canal?

<p>The two primary nerve plexuses are the submucosal nerve plexus and the myenteric nerve plexus.</p> Signup and view all the answers

Which structure in the stomach prevents backflow of food into the esophagus?

<p>The cardioesophageal sphincter prevents backflow into the esophagus.</p> Signup and view all the answers

Describe the role of the pyloric sphincter in the digestive system.

<p>The pyloric sphincter controls the passage of food from the stomach into the small intestine.</p> Signup and view all the answers

What anatomical feature allows the stomach to expand as it fills with food?

<p>The stomach's ability to stretch is facilitated by its rugae, which are folds in the stomach lining.</p> Signup and view all the answers

How do the greater and lesser omentum differ in their functions within the abdominal cavity?

<p>The greater omentum stores fat and provides insulation while the lesser omentum connects the stomach to the liver.</p> Signup and view all the answers

Which two components are crucial for the regulation of GI tract mobility?

<p>The intrinsic nerve plexuses, specifically the submucosal and myenteric plexuses, are crucial.</p> Signup and view all the answers

What is the unique shape and standard position of the stomach in the human body?

<p>The stomach is C-shaped and located on the left side of the abdominal cavity.</p> Signup and view all the answers

What is the significance of the visceral and parietal peritoneum in abdominal cavity structures?

<p>The visceral peritoneum covers abdominal organs, while the parietal peritoneum lines the abdominal wall.</p> Signup and view all the answers

What are the primary components found in bile produced by the liver?

<p>Bile contains bile salts, bile pigments (mainly bilirubin), cholesterol, phospholipids, and electrolytes.</p> Signup and view all the answers

What is the significance of the cystic duct in the storage and release of bile?

<p>The cystic duct allows the bile to flow back to the gallbladder for storage when digestion is not occurring.</p> Signup and view all the answers

How does the gallbladder respond when fatty food enters the duodenum?

<p>The gallbladder contracts and spurts out stored bile into the duodenum to aid in fat digestion.</p> Signup and view all the answers

Describe the pathway bile takes from the liver to the duodenum.

<p>Bile leaves the liver via the common hepatic duct, travels through the bile duct, and enters the duodenum.</p> Signup and view all the answers

What role does bile play in the digestion of fats?

<p>Bile emulsifies fats, breaking them down into smaller droplets for easier digestion by enzymes.</p> Signup and view all the answers

What process occurs to bile while it is stored in the gallbladder?

<p>Bile is concentrated in the gallbladder through the removal of water.</p> Signup and view all the answers

Identify the location of the liver's bile ducts and their role.

<p>The right and left hepatic ducts converge to form the common hepatic duct, which transports bile from the liver.</p> Signup and view all the answers

What is bilirubin and its significance in bile production?

<p>Bilirubin is a bile pigment derived from the breakdown of hemoglobin and is a key component of bile.</p> Signup and view all the answers

What enzyme primarily digests proteins in the stomach?

<p>Pepsin is the enzyme that primarily digests proteins in the stomach.</p> Signup and view all the answers

What is the primary digestive action of the pylorus?

<p>The pylorus acts as a pump that meters out chyme into the small intestine.</p> Signup and view all the answers

Which substances are predominantly absorbed in the stomach?

<p>Alcohol and aspirin are virtually the only substances absorbed in the stomach.</p> Signup and view all the answers

What is the timeframe for the stomach to empty its contents after a meal?

<p>The stomach typically empties its contents in 4 to 6 hours.</p> Signup and view all the answers

What process occurs when peristaltic waves force contents back into the stomach?

<p>This process is called retropulsion.</p> Signup and view all the answers

What is the role of intestinal enzymes in the digestive process?

<p>Intestinal enzymes break down double sugars into simple sugars and complete some protein digestion.</p> Signup and view all the answers

Which enzyme is specifically involved in digesting milk protein in infants?

<p>Rennin is the enzyme that digests milk protein in infants.</p> Signup and view all the answers

What characteristic provides the stomach with its ability to stretch?

<p>The stomach has muscular layers and rugae that allow it to stretch.</p> Signup and view all the answers

What is the typical average caloric output of the BMR per hour for a 70-kg adult?

<p>About 60 to 72 kcal/hour.</p> Signup and view all the answers

Name one major factor that influences BMR and explain how it affects metabolic rate.

<p>Surface area; a smaller body typically has a higher BMR because of a higher heat loss relative to body mass.</p> Signup and view all the answers

What is the relationship between thyroxine levels and the metabolic rate?

<p>Higher levels of thyroxine result in a higher metabolic rate.</p> Signup and view all the answers

What is the total metabolic rate (TMR) and what must it equal to maintain homeostasis?

<p>TMR is the total kilocalories the body must consume, and it must equal the calories consumed to maintain homeostasis.</p> Signup and view all the answers

How does the body primarily lose heat during temperature regulation?

<p>Through the radiation of heat from the skin and the evaporation of sweat.</p> Signup and view all the answers

What part of the brain is responsible for regulating body temperature, and what role does it play?

<p>The hypothalamus; it initiates mechanisms to maintain body temperature through heat loss or heat-promoting methods.</p> Signup and view all the answers

Describe the temperature range the human body must maintain for homeostasis.

<p>Between 35.6ºC and 37.8ºC (96ºF and 100ºF).</p> Signup and view all the answers

What effect does muscle activity have on total metabolic rate?

<p>Muscle activity dramatically increases the total metabolic rate.</p> Signup and view all the answers

Study Notes

Digestive System and Body Metabolism

  • The digestive system has four main functions: ingestion, digestion, absorption, and defecation. Ingestion is taking in food, digestion is breaking food down into nutrient molecules, absorption is moving those nutrients into the bloodstream, and defecation is ridding the body of indigestible waste.

Anatomy of the Digestive System

  • Two main organ groups: the alimentary canal (GI tract) and accessory digestive organs.
  • The GI tract is a continuous, coiled, hollow tube that runs from the mouth to the anus. These organs are responsible for ingestion, digestion, absorption, and defecation.
  • Accessory digestive organs include teeth, tongue, and several large digestive organs. They assist in digestion in various ways.

Organs of the Alimentary Canal

  • Mouth (oral cavity)
  • Pharynx
  • Esophagus
  • Stomach
  • Small intestine
  • Large intestine
  • Anus

Anatomy of the Mouth

  • Mouth (oral cavity)—a mucous membrane-lined cavity.
  • Lips (labia)—anterior opening protection.
  • Cheeks—lateral walls.
  • Hard palate—anterior roof
  • Soft palate—posterior roof.
  • Uvula—fleshy projection of the soft palate.
  • Vestibule—area between the lips and teeth externally, and gums internally.
  • Oral cavity proper—area contained by the teeth.
  • Tongue—attached at the hyoid bone, styloid processes of the skull, and the lingual frenulum.
  • Tonsils (palatine and lingual)— located at the posterior end of the oral cavity, and at the base of the tongue respectively .

Functions of the Mouth

  • Mastication (chewing) of food
  • Tongue mixes masticated food with saliva.
  • Tongue initiates swallowing.
  • Taste buds on the tongue allow for taste. Papillae containing taste buds or taste receptors are found on the tongue surface.

Pharynx

  • Passageway for food, fluids, and air.
  • Food passes from the mouth posteriorly into the oropharynx (posterior to the oral cavity) and laryngopharynx (below the oropharynx and continuous with the esophagus).
  • Food is propelled to the esophagus by skeletal muscle layers (longitudinal outer layer and circular inner layer) via alternating contractions (peristalsis).

Esophagus

  • Anatomy: about 10 inches long, runs from pharynx to stomach.
  • Physiology: conducts food to the stomach by peristalsis; passageway for food only; respiratory system branches off after the pharynx.

Layers of Tissue in the Alimentary Canal Organs

  • Four layers from innermost to outermost: mucosa, submucosa, muscularis externa, and serosa.
  • Mucosa: innermost moist membrane consisting of surface epithelium, lamina propria (connective tissue), and a scant smooth muscle layer; lines the lumen (cavity).
  • Submucosa: soft connective tissue with blood vessels, nerve endings, mucosa-associated lymphoid tissue (MALT), and lymphatic vessels, just beneath the mucosa
  • Muscularis externa: smooth muscle (inner circular layer and outer longitudinal layer).
  • Serosa: outermost layer of the wall; contains fluid-producing cells, includes visceral peritoneum (innermost layer continuous with outermost layer) and parietal peritoneum (outermost layer lining the abdominopelvic cavity via the mesentery).
  • Intrinsic nerve plexuses: myenteric and submucosal regulate GI tract mobility and secretory activity.

Stomach

  • C-shaped organ on the left side of the abdominal cavity.
  • Food enters at the cardioesophageal sphincter from the esophagus; empties into the small intestine at the pyloric sphincter.
  • Regions: cardia (near the heart), fundus (expanded portion lateral to the cardiac region), body (midportion), pylorus (funnel-shaped terminal end)
  • Greater and lesser curvature (convex and concave medial surfaces respectively).
  • Rugae-internal folds of the mucosa when empty.
  • The stomach holds 4L of food.
  • The stomach mucosa consists of simple columnar epithelium, mostly mucous cells, which produce bicarbonate-rich alkaline mucus
  • Lined with gastric pits that lead to gastric glands secreting gastric juice, including intrinsic factor, needed for vitamin B12 absorption, chief cells (produce protein-digesting enzymes like pepsinogens), parietal cells (produce hydrochloric acid that activates enzymes), and mucous neck cells (produce thin acidic mucus).
  • Functions: temporary storage tank; site of food breakdown; chemical breakdown of protein begins; delivers chyme (processed food) to the small intestine.
  • Pyloric sphincter controls food release.
  • Peristaltic waves push and mix churning food.

Small Intestine

  • Body's major digestive organ; 7-13ft long. Extends from the pyloric sphincter to the ileocecal valve.
  • Subdivisions: duodenum, jejunum, ileum.
  • Chemical digestion begins here. Enzymes produced by intestinal cells and pancreas are carried to the duodenum. Bile from the liver enters the duodenum via the bile duct, joining the main pancreatic duct at the hepatopancreatic ampulla.
  • Structural modifications (increase area for absorption): villi (fingerlike projections with capillary beds and lacteals), microvilli (tiny projections of the plasma membrane with brush border enzymes), and circular folds (plicae circulares).
  • Peyer's patches are collections of lymphatic tissue located in the submucosa.

Large Intestine

  • Larger in diameter, but shorter than the small intestine; extends from the ileocecal valve to the anus
  • Subdivisions: cecum (saclike first part, appendix), colon (ascending, transverse, descending, and sigmoid—S-shaped), rectum, and anal canal.
  • Goblet cells produce alkaline mucus to lubricate the passage of feces.
  • Muscularis externa is reduced to three bands of muscle (teniae coli), creating haustra (pocketlike sacs).

Accessory Digestive Organs

  • Teeth
  • Salivary glands
  • Pancreas
  • Liver
  • Gallbladder

Teeth

  • Masticate food into smaller fragments.
  • Humans have two sets: deciduous (baby) teeth (20 by age 2) and permanent teeth (32).
  • Teeth are classified by function (incisors, canines, premolars, molars): cutting, tearing, piercing, and grinding.
  • Teeth have two major regions: crown and root.
    • Crown: enamel covers it. Dentin forms most of the tooth and contains the pulp cavity with blood vessels and nerve fibers (pulp). Root canal where the pulp cavity extends into the root
    • Root: Cement covering the outer surface and periodontal membrane attaching tooth to jaw.

Salivary Glands

  • Three pairs (parotid, submandibular, sublingual) that empty secretions into the mouth.
  • Saliva: a mixture of mucus and serous fluids; moistens and binds food into a bolus, containing amylase for starch digestion, lysozymes and antibodies to inhibit bacteris.

Pancreas

  • Soft, pink, triangular gland.
  • Posterior to the parietal peritoneum and mostly retroperitoneal.
  • Extends across the abdomen from spleen to duodenum.
  • Produces a wide spectrum of digestive enzymes and alkaline fluid introduced to neutralize acidic chyme.
  • Pancreas produces hormones (insulin and glucagon).

Liver

  • Largest gland in the body.
  • Located on the right side under the diaphragm.
  • Composed of four lobes, suspended from the diaphragm and abdominal wall by the falciform ligament. Liver manufactures bile, detoxifies drugs and alcohol, degrades hormones produces cholesterol, albumin, and clotting proteins.
  • Plays a central role in metabolism.
  • Liver can regenerate from damage or removal.

Gallbladder

  • Green sac in a shallow fossa in the liver's inferior surface.
  • Stores bile when digestion isn't occurring.
  • Concentrates bile by removing water.
  • Releases stored bile into the duodenum when fatty food arrives.

Functions of the Digestive System

  • Overview of gastrointestinal processes and controls, digestion, and absorption.

Overview of Gastrointestinal Processes and Controls

  • Ingestion: placing food into the mouth.
  • Propulsion: movement of food from one digestive region to another via peristalsis and segmentation (mixing in the small intestine).

Activities in the Mouth, Pharynx, and Esophagus

  • Ingestion and breakdown
  • Food is placed in the mouth, physically broken down by chewing, and mixed with saliva containing amylase for starch digestion. Essentially, no food absorption occurs in the mouth
  • Swallowing (deglutition) occurs in two phases: the voluntary buccal phase in the mouth; the involuntary pharyngeal-esophageal phase where the pharynx and esophagus transport the bolus (mass of food) to the stomach via peristalsis. The cardioesophageal sphincter opens to let food enter the stomach

Activities in the Stomach

  • Food breakdown: gastric juice is regulated by neural and hormonal factors; the presence of food or rising pH triggers the release of the hormone gastrin; gastrin causes stomach glands to produce protein-digesting enzymes, mucus, and hydrochloric acid.
  • Hydrochloric acid makes the stomach contents very acidic; activates pepsinogen to pepsin for protein digestion; provides a hostile environment for microorganisms; alcohol and aspirin are virtually the only items absorbed in the stomach.
  • Food propulsion: peristaltic waves occur from the fundus to the pylorus, forcing food past the pyloric sphincter; the pylorus meters out chyme into the small intestine (3 ml at a time); retropulsion (peristaltic waves close the pyloric sphincter), forcing contents back into the stomach; stomach empties in 4–6 hours.

Activities of the Small Intestine

  • Chyme breakdown and absorption; intestinal enzymes from the brush border function to break double sugars into simple sugars, complete some protein digestion; intestinal enzymes and pancreatic enzymes help to complete digestion of all food groups; pancreatic enzymes play the major role in the digestion of fats, proteins, and carbohydrates; alkaline content neutralizes acidic chyme and facilitates enzymatic function.
  • Release of pancreatic juice from the pancreas into the duodenum is stimulated by vagus nerves and hormones (secretin and cholecystokinin (CCK)). CCK also stimulates the liver and gallbladder to release bile, an emulsifier to facilitate fat absorption and that is needed for absorption of fat-soluble vitamins (K, D, E, and A).
  • Chyme propulsion and segmentation, mix chyme with digestive juices; assist in propelling food.
  • Water and end products of digestion are absorbed; most are absorbed by active transport through cell membranes, while lipids are absorbed by diffusion; substances are transported to the liver by the hepatic portal vein or lymph.

Activities of the Large Intestine

  • Nutrient breakdown and absorption. No digestive enzymes. Resident bacteria digest remaining nutrients; produce some vitamins K and B.
  • Water, vitamins, ions, and remaining water are absorbed.
  • Remaining materials are eliminated via feces, containing undigested food residues, mucus, bacteria, and water.
  • Propulsion and defecation; sluggish peristalsis when food residue arrives; haustral contractions are frequent; mass movements are slow, powerful movements. Presence of feces causes a defecation reflex, internal anal sphincter relaxes, and voluntary (external) anal sphincter relaxes and defecation occurs.

Part III: Developmental Aspects of the Digestive System and Metabolism

  • The alimentary canal is present by the fifth week of development; digestive glands arise from the mucosa of the canal; the fetus receives nutrients through the placenta.

  • Newborns have feeding needs that are frequent, with inefficient/sluggish peristalsis and common vomiting.

  • The rooting and sucking reflexes help newborns to find and take nourishment. Teething begins around age 6 months.

  • Problems:

    • Gastroenteritis (intestinal tract inflammation) at any age.
    • Appendicitis (appendicitis) common in adolescents
    • Middle age issues (ulcers, gallbladder problems, and decreased metabolic rate)
    • Later middle age (Obesity, diabetes mellitus increased gastrointestinal issues and cancer rates).

Part II: Nutrition and Metabolism

  • Most foods are metabolized into energy for cells, measured in kilocalories.
  • Major nutrients (carbohydrates, lipids, proteins, and water) and minor nutrients (vitamins and minerals).
  • A diet consisting of foods from the five food groups guarantees adequate amounts of all needed nutrients.
  • Dietary recommendations for these nutrients exist and include the Healthy Eating Pyramid (1992) and MyPlate (2011).

Carbohydrate Metabolism

  • Preferred source for cellular energy (ATP) through glucose breakdown and oxidation, via glycolysis, citric acid cycle, and electron transport chain.
  • Hyperglycemia and hypoglycemia issues can occur with glucose imbalances.

Fat Metabolism

  • Provides reserve energy, insulates, and protects organs.
  • Excessive fat breakdown causes acidosis.

Protein Metabolism

  • Proteins are the building blocks of cell structures and functional molecules.
  • Oxidized when other fuel sources are limited to form ATP.
  • Liver detoxifies ammonia (released during protein catabolism) by combining it with carbon dioxide to form urea.

The Central Role of the Liver in Metabolism

  • Liver is the main metabolic organ for various processes (bile production, drug/alcohol detoxification, hormone breakdown, cholesterol metabolism).
  • Liver performs: (glycogenesis, glycogenolysis, and gluconeogenesis).
  • Involved in fat and amino acid metabolism, and blood protein production (e.g., albumin and clotting proteins).

Body Energy Balance

  • Energy intake equals total energy output (heat, work, and energy storage).
  • Body temperature regulation via the hypothalamus. Mechanisms that control body heat loss (radiation of heat from skin, sweating) or heat production (vasoconstriction of blood vessels to skin, shivering).
  • Fever is uncontrolled hyperthermia caused by infection.
  • Basic metabolic rate (BMR) is the amount of heat produced by the body per unit time at rest. Factors that affect BMR include surface area, gender, age, and thyroxine production.
  • Total metabolic rate (TMR) is the amount of kilocalories the body must consume to fuel ongoing activities. It increases with muscle activity, requiring equivalent calorie consumption in a well-balanced diet.
  • Interference with energy balance leads to obesity or malnutrition.

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Chapter 14 Digestive System PDF

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Explore the key functions and anatomy of the digestive system, including the roles of the alimentary canal and accessory digestive organs. This quiz covers essential knowledge on digestion, absorption, and the organs involved throughout the gastrointestinal tract.

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