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Questions and Answers
What is a cyst?
What is a cyst?
What distinguishes a true cyst from a false cyst?
What distinguishes a true cyst from a false cyst?
Where can a sequestration dermoid be found?
Where can a sequestration dermoid be found?
What type of material might be found in a sequestration dermoid?
What type of material might be found in a sequestration dermoid?
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What is a sinus?
What is a sinus?
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Which of the following is an acquired cause of sinus?
Which of the following is an acquired cause of sinus?
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What is the cause of a thyroglossal fistula?
What is the cause of a thyroglossal fistula?
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What is the cause of a tracheo-oesophageal fistula?
What is the cause of a tracheo-oesophageal fistula?
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Which factor can lead to the persistence of a sinus or fistula?
Which factor can lead to the persistence of a sinus or fistula?
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What is an arterio-venous fistula (A-V fistula)?
What is an arterio-venous fistula (A-V fistula)?
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What is the characteristic feature of a traumatic cyst?
What is the characteristic feature of a traumatic cyst?
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What is the defining feature of a retention cyst?
What is the defining feature of a retention cyst?
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What is the primary cause of parasitic cysts?
What is the primary cause of parasitic cysts?
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What is the primary complication associated with cysts?
What is the primary complication associated with cysts?
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Which imaging technique may be required for deep-seated intra-abdominal or thoracic cysts?
Which imaging technique may be required for deep-seated intra-abdominal or thoracic cysts?
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What is the primary characteristic feature of an ulcer?
What is the primary characteristic feature of an ulcer?
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What is the defining characteristic feature of a fistula?
What is the defining characteristic feature of a fistula?
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What is the primary management approach for ulcers?
What is the primary management approach for ulcers?
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What is the primary approach for managing fistulas?
What is the primary approach for managing fistulas?
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What are compression symptoms associated with?
What are compression symptoms associated with?
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What is one of the most common causes of inflammation?
What is one of the most common causes of inflammation?
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Which microbes can cause inflammation?
Which microbes can cause inflammation?
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What are the characteristic responses of living tissue to injury?
What are the characteristic responses of living tissue to injury?
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What do bacteria release that can contribute to inflammation?
What do bacteria release that can contribute to inflammation?
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What are the stimuli for acute inflammation?
What are the stimuli for acute inflammation?
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What characterizes chronic inflammation?
What characterizes chronic inflammation?
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What can cause chronic inflammation?
What can cause chronic inflammation?
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What can cause endothelial damage leading to acute inflammation?
What can cause endothelial damage leading to acute inflammation?
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What is the response to an injury or infection that typically resolves once the injury has been addressed or the infection has been cleared?
What is the response to an injury or infection that typically resolves once the injury has been addressed or the infection has been cleared?
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What chemical mediators can cause endothelial cell retraction leading to intercellular gaps and vascular leakage?
What chemical mediators can cause endothelial cell retraction leading to intercellular gaps and vascular leakage?
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What can cause chronic inflammation in autoimmune diseases?
What can cause chronic inflammation in autoimmune diseases?
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What can result in chronic inflammation?
What can result in chronic inflammation?
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Under what conditions does chronic inflammation tend to occur?
Under what conditions does chronic inflammation tend to occur?
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What are some examples of autoimmune diseases with chronic inflammation as a common component?
What are some examples of autoimmune diseases with chronic inflammation as a common component?
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What can result from the multiplication of viruses inside host cells?
What can result from the multiplication of viruses inside host cells?
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What can bacteria emit that causes hypersensitivity reactions?
What can bacteria emit that causes hypersensitivity reactions?
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What can physical or chemical agents such as irritants and corrosive substances cause?
What can physical or chemical agents such as irritants and corrosive substances cause?
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What results from insufficient oxygen or nutrients due to inadequate blood flow?
What results from insufficient oxygen or nutrients due to inadequate blood flow?
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What are the systemic effects of inflammation?
What are the systemic effects of inflammation?
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"Fever is thought to enhance the efficiency of leukocyte killing and impair the replication of many invading organisms." This statement is associated with which condition?
"Fever is thought to enhance the efficiency of leukocyte killing and impair the replication of many invading organisms." This statement is associated with which condition?
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What can persistent inflammation lead to?
What can persistent inflammation lead to?
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What can inflammation affect that leads to neurological disorders such as multiple sclerosis, Alzheimer's disease, and Parkinson's disease?
What can inflammation affect that leads to neurological disorders such as multiple sclerosis, Alzheimer's disease, and Parkinson's disease?
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What plays a crucial role in the pathogenesis of many diseases and can be both protective and harmful?
What plays a crucial role in the pathogenesis of many diseases and can be both protective and harmful?
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What is essential for maintaining optimal health?
What is essential for maintaining optimal health?
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What is a common systemic response to inflammation often associated with infection?
What is a common systemic response to inflammation often associated with infection?
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Study Notes
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b-Tubuloembryonic cysts: collection of embryonic remnants, includes ependymal cyst (thryoglossal cyst, Ependymal cyst), acquired, and parasitic cysts.
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Cysts can be classified based on their origin:
- Retention cysts: result from the accumulation of secretion in glands due to obstruction of ducts (sebaceous cyst, parotid gland cyst).
- Traumatic cysts: caused by injury, such as a cystic tumor (cystic teratoma, cystadenoma).
- Degeneration cyst: degenerative changes within a cyst.
- Distension cyst: distension from the accumulation of fluid within a cyst (thyroid cyst, lymphatic cyst, hydrocele).
- Parasitic cyst: caused by parasitic infestation, such as a hydatid cyst.
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Clinical features vary according to site and size of the cyst:
- Pain: enlarging cysts, secondary to haemorrhage, infection, rupture, or torsion.
- Compression symptoms: haemorrhage in thyroglossal cyst, large ovarian cyst, obstruction to pelvic veins, causing varicose veins of the lower limbs.
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Diagnosis can be obvious in superficial cysts but may require ultrasound, CT scan, or MRI for deep-seated intra-abdominal or thoracic cysts.
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Complications include infection, haemorrhage, torsion, obstruction, calcification, and malignancy (rare).
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An ulcer is a break in the continuity of an epithelial surface, characterized by progressive destruction of the epithelium and a granulating base.
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Clinical examination includes assessment of size, shape, edge, floor, base, discharge, surrounding area, and lymph nodes.
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Management involves treating the cause of the ulcer, identifying and correcting comorbid factors, adequate drainage and debridement, antiseptics and topical antibiotics, and wound dressings (hydrogel, alginate, lyofoam, tegaderm, alleyn).
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A fistula is a communicating track between two epithelial surfaces, commonly between a hollow viscus and the skin (external fistula) or between two hollow viscera (internal fistula). The track is lined with granulation tissue and subsequently epithelialized.
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Fistulas require accurate assessment, as well as treatment of the underlying cause, drainage, and wound care with hydrogel, alginate, lyofoam, tegaderm, and alleyn.
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Viruses can cause cell death through multiplication inside host cells, leading to cell death or cell explosion, resulting in additional death.
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Bacteria emit specific gases (toxins) that can cause hypersensitivity reactions, resulting in inappropriate or excessive immune responses that damage tissues.
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Physical or chemical agents such as irritants and corrosive substances cause tissue damage leading to inflammation, which may occur through physical trauma, ultraviolet or other ionizing radiation, burns or excessive cooling (frostbite).
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Tissue necrosis, death of tissues, results from insufficient oxygen or nutrients due to inadequate blood flow, which is a potent inflammatory stimulus, often accompanied by an acute inflammatory response.
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Inflammation has both systemic and local effects. Systemic effects include fever, malaise, and leukocytosis, which is the presence of an abnormally high number of circulating white blood cells, often indicating a bacterial infection in the case of increased neutrophils, or a viral infection in the case of increased lymphocytes.
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Fever is a common systemic response to inflammation, often associated with infection, and is thought to enhance the efficiency of leukocyte killing and impair the replication of many invading organisms.
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Persistent inflammation can lead to chronic diseases such as arthritis, atherosclerosis, and cancer, and can result in tissue damage and fibrosis.
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Inflammation can also affect the central nervous system, leading to neurological disorders such as multiple sclerosis, Alzheimer's disease, and Parkinson's disease.
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The immune response to inflammation plays a crucial role in the pathogenesis of many diseases and can be both protective and harmful. A balanced immune response is essential for maintaining optimal health.
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Description
Test your knowledge about cysts, ulcers, fistulas, and sinuses. Learn about the characteristics of cysts including being fluid-filled sacs bound by a wall, the types of cysts, and their contents.