Mitochondrial Electron Transport Chain Quiz

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Questions and Answers

Which complex in the mitochondrial electron transport chain is responsible for pumping 4H+ out of the mitochondrial matrix?

  • Complex I (correct)
  • Complex III
  • Complex II
  • Complex IV

What compound is generated by Complex II in the electron transport chain?

  • Succinate
  • FADH
  • QH2 (correct)
  • NAD+

Where are electrons transferred to in Complex I of the electron transport chain?

  • FAD
  • Ubiquinone (Q) (correct)
  • NAD+
  • Succinate

Which dehydrogenase enzyme is involved in Complex I of the mitochondrial electron transport chain?

<p>NADH dehydrogenase (B)</p> Signup and view all the answers

Which complex generates FADH2 in the electron transport chain?

<p>Complex II (A)</p> Signup and view all the answers

How many protons are pumped out of the mitochondrial matrix by Complex II in the electron transport chain?

<p>No protons (B)</p> Signup and view all the answers

What is the overall mechanism of electron transfer in Complex I?

<p>$Q \to QH_2$ (B)</p> Signup and view all the answers

Which complex in the electron transport chain is sometimes referred to as succinate dehydrogenase?

<p>$FADH_2$ reductase (B)</p> Signup and view all the answers

Which complex in the electron transport chain takes 4 electrons from cytochrome c?

<p>Complex IV (C)</p> Signup and view all the answers

What is the function of a respirasome?

<p>Assists with substrate channeling (A)</p> Signup and view all the answers

Which poison inhibits Complex III in the electron transport chain?

<p>Cyanide (CN–) (B)</p> Signup and view all the answers

How do uncouplers affect the electron transport chain?

<p>Generate heat instead of ATP (B)</p> Signup and view all the answers

Which electron carrier is found in Complex III of the electron transport chain?

<p>Cyt bH (D)</p> Signup and view all the answers

What is the main function of Complex I in the electron transport chain?

<p>Pumps 2H+ out of the mitochondrial matrix (A)</p> Signup and view all the answers

Which poison acts on ATP synthase in the electron transport chain?

<p>Antimycin A1 (D)</p> Signup and view all the answers

What is the function of Complex III in the electron transport chain?

<p>Transferring electrons to cytochrome c (B)</p> Signup and view all the answers

What is the role of Ubiquinone in the Q Pool Defined?

<p>Containing oxidized and reduced forms in the mitochondrial membrane (D)</p> Signup and view all the answers

Why is cytochrome c referred to as a soluble electron carrier?

<p>It can move freely between complexes in the electron transport chain (A)</p> Signup and view all the answers

What differentiates QH2 from cytochrome c in terms of electron carriers?

<p>QH2 carries only one electron while cytochrome c carries two electrons (C)</p> Signup and view all the answers

What is the primary function of Complex IV in electron transport?

<p>Reducing O2 to H2O (A)</p> Signup and view all the answers

Which component of the electron transport chain involves Fe and Cu as electron carriers?

<p>Complex IV (B)</p> Signup and view all the answers

'Q Cycle and Electron Transport' addresses which significant issue faced by the electron transport chain?

<p>Leakiness of the electron transport chain (C)</p> Signup and view all the answers

What is the main responsibility of ATP synthase?

<p>Producing ATP (D)</p> Signup and view all the answers

Which complex of ATP synthase contains multiple subunits?

<p>F1 complex (A)</p> Signup and view all the answers

What rotates in the F0 complex of ATP synthase as protons move between subunits?

<p>c subunit (B)</p> Signup and view all the answers

What forces conformational changes in the F1 complex of ATP synthase?

<p>Spinning shaft (A)</p> Signup and view all the answers

Which part of ATP synthase is turned by protons moving through the F0 complex?

<p>$ ext{γ subunit}$ (D)</p> Signup and view all the answers

What is the electrochemical potential derived from the uneven distribution of electrons across the inner mitochondrial matrix called?

<p>$ ext{Proton Motive Force}$ (C)</p> Signup and view all the answers

Which enzyme is primarily responsible for producing ATP from ADP and Pi?

<p>$ ext{ATP Synthase}$ (B)</p> Signup and view all the answers

In which complex do protons move between a and b subunits?

<p>$ ext{F0}$ complex (D)</p> Signup and view all the answers

What occurs to form ATP in ATP Synthase?

<p>$ ext{Binding of ADP and Pi}$ (D)</p> Signup and view all the answers

What type of catalysis does ATP Synthase exhibit during rotation?

<p>$ ext{Rotational}$ (B)</p> Signup and view all the answers

Match the following components with their roles in the electron transport chain:

<p>Complex III = Transfer electrons from coenzyme Q to cytochrome c Cytochrome c = Shuttles electrons between Complex III and Complex IV Complex IV = Transfers electrons from cytochrome c to oxygen Coenzyme Q = Accepts electrons from Complex I and Complex II</p> Signup and view all the answers

Match the following TCA cycle intermediates with their specific roles:

<p>Citrate = Formed from condensation of oxaloacetate and acetyl-CoA Isocitrate = Undergoes oxidative decarboxylation to form alpha-ketoglutarate Succinyl-CoA = Generates GTP through substrate-level phosphorylation Malate = Converted to oxaloacetate in the last step of the cycle</p> Signup and view all the answers

Match the following processes with their outcomes in oxidative phosphorylation:

<p>Proton pumping by Complex I = Contributes to establishing the proton gradient across the inner mitochondrial membrane ATP synthase activity = Converts the proton gradient into ATP production Oxygen consumption at Complex IV = Forms water as a byproduct Electron transfer through Complex II = Contributes electrons directly to the electron transport chain</p> Signup and view all the answers

Match the following terms with their descriptions related to electron transport chain regulation:

<p>Allosteric regulation of dehydrogenases by NADH = Inhibits energy production when NADH levels are high Anaplerotic reactions = Replenish citric acid cycle intermediates to maintain metabolic flux Regulation based on substrate availability = Increased substrates enhance pathway flux Role of Ca2+ as an allosteric regulator = Impacts mitochondrial function under varying calcium levels</p> Signup and view all the answers

Match the following molecules with their contributions to electron transfer in oxidative phosphorylation:

<p>FADH2 = Donates electrons directly to the electron transport chain at Complex II NADH = Supplies electrons to Complex I, initiating the electron flow Cytochrome c = Transfers electrons between Complexes III and IV Ubiquinone (Coenzyme Q) = Accepts electrons from both Complex I and Complex II</p> Signup and view all the answers

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