37 Questions
Which complex in the mitochondrial electron transport chain is responsible for pumping 4H+ out of the mitochondrial matrix?
Complex I
What compound is generated by Complex II in the electron transport chain?
QH2
Where are electrons transferred to in Complex I of the electron transport chain?
Ubiquinone (Q)
Which dehydrogenase enzyme is involved in Complex I of the mitochondrial electron transport chain?
NADH dehydrogenase
Which complex generates FADH2 in the electron transport chain?
Complex II
How many protons are pumped out of the mitochondrial matrix by Complex II in the electron transport chain?
No protons
What is the overall mechanism of electron transfer in Complex I?
$Q \to QH_2$
Which complex in the electron transport chain is sometimes referred to as succinate dehydrogenase?
$FADH_2$ reductase
Which complex in the electron transport chain takes 4 electrons from cytochrome c?
Complex IV
What is the function of a respirasome?
Assists with substrate channeling
Which poison inhibits Complex III in the electron transport chain?
Cyanide (CN–)
How do uncouplers affect the electron transport chain?
Generate heat instead of ATP
Which electron carrier is found in Complex III of the electron transport chain?
Cyt bH
What is the main function of Complex I in the electron transport chain?
Pumps 2H+ out of the mitochondrial matrix
Which poison acts on ATP synthase in the electron transport chain?
Antimycin A1
What is the function of Complex III in the electron transport chain?
Transferring electrons to cytochrome c
What is the role of Ubiquinone in the Q Pool Defined?
Containing oxidized and reduced forms in the mitochondrial membrane
Why is cytochrome c referred to as a soluble electron carrier?
It can move freely between complexes in the electron transport chain
What differentiates QH2 from cytochrome c in terms of electron carriers?
QH2 carries only one electron while cytochrome c carries two electrons
What is the primary function of Complex IV in electron transport?
Reducing O2 to H2O
Which component of the electron transport chain involves Fe and Cu as electron carriers?
Complex IV
'Q Cycle and Electron Transport' addresses which significant issue faced by the electron transport chain?
Leakiness of the electron transport chain
What is the main responsibility of ATP synthase?
Producing ATP
Which complex of ATP synthase contains multiple subunits?
F1 complex
What rotates in the F0 complex of ATP synthase as protons move between subunits?
c subunit
What forces conformational changes in the F1 complex of ATP synthase?
Spinning shaft
Which part of ATP synthase is turned by protons moving through the F0 complex?
$ ext{γ subunit}$
What is the electrochemical potential derived from the uneven distribution of electrons across the inner mitochondrial matrix called?
$ ext{Proton Motive Force}$
Which enzyme is primarily responsible for producing ATP from ADP and Pi?
$ ext{ATP Synthase}$
In which complex do protons move between a and b subunits?
$ ext{F0}$ complex
What occurs to form ATP in ATP Synthase?
$ ext{Binding of ADP and Pi}$
What type of catalysis does ATP Synthase exhibit during rotation?
$ ext{Rotational}$
Match the following components with their roles in the electron transport chain:
Complex III = Transfer electrons from coenzyme Q to cytochrome c Cytochrome c = Shuttles electrons between Complex III and Complex IV Complex IV = Transfers electrons from cytochrome c to oxygen Coenzyme Q = Accepts electrons from Complex I and Complex II
Match the following TCA cycle intermediates with their specific roles:
Citrate = Formed from condensation of oxaloacetate and acetyl-CoA Isocitrate = Undergoes oxidative decarboxylation to form alpha-ketoglutarate Succinyl-CoA = Generates GTP through substrate-level phosphorylation Malate = Converted to oxaloacetate in the last step of the cycle
Match the following processes with their outcomes in oxidative phosphorylation:
Proton pumping by Complex I = Contributes to establishing the proton gradient across the inner mitochondrial membrane ATP synthase activity = Converts the proton gradient into ATP production Oxygen consumption at Complex IV = Forms water as a byproduct Electron transfer through Complex II = Contributes electrons directly to the electron transport chain
Match the following terms with their descriptions related to electron transport chain regulation:
Allosteric regulation of dehydrogenases by NADH = Inhibits energy production when NADH levels are high Anaplerotic reactions = Replenish citric acid cycle intermediates to maintain metabolic flux Regulation based on substrate availability = Increased substrates enhance pathway flux Role of Ca2+ as an allosteric regulator = Impacts mitochondrial function under varying calcium levels
Match the following molecules with their contributions to electron transfer in oxidative phosphorylation:
FADH2 = Donates electrons directly to the electron transport chain at Complex II NADH = Supplies electrons to Complex I, initiating the electron flow Cytochrome c = Transfers electrons between Complexes III and IV Ubiquinone (Coenzyme Q) = Accepts electrons from both Complex I and Complex II
Test your knowledge on the mitochondrial electron transport chain including Complex IV and the formation of respirasome. Learn about the electron carriers, electron transfer, and the final electron acceptor in this crucial process of cellular respiration.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
