Mitochondrial Electron Transport Chain Quiz
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Questions and Answers

Which complex in the mitochondrial electron transport chain is responsible for pumping 4H+ out of the mitochondrial matrix?

  • Complex I (correct)
  • Complex III
  • Complex II
  • Complex IV

    • What compound is generated by Complex II in the electron transport chain?

  • Succinate
  • FADH
  • QH2 (correct)
  • NAD+

    • Where are electrons transferred to in Complex I of the electron transport chain?

  • FAD
  • Ubiquinone (Q) (correct)
  • NAD+
  • Succinate

    • Which dehydrogenase enzyme is involved in Complex I of the mitochondrial electron transport chain?

    <p>NADH dehydrogenase</p> Signup and view all the answers

    Which complex generates FADH2 in the electron transport chain?

    <p>Complex II</p> Signup and view all the answers

    How many protons are pumped out of the mitochondrial matrix by Complex II in the electron transport chain?

    <p>No protons</p> Signup and view all the answers

    What is the overall mechanism of electron transfer in Complex I?

    <p>$Q \to QH_2$</p> Signup and view all the answers

    Which complex in the electron transport chain is sometimes referred to as succinate dehydrogenase?

    <p>$FADH_2$ reductase</p> Signup and view all the answers

    Which complex in the electron transport chain takes 4 electrons from cytochrome c?

    <p>Complex IV</p> Signup and view all the answers

    What is the function of a respirasome?

    <p>Assists with substrate channeling</p> Signup and view all the answers

    Which poison inhibits Complex III in the electron transport chain?

    <p>Cyanide (CN–)</p> Signup and view all the answers

    How do uncouplers affect the electron transport chain?

    <p>Generate heat instead of ATP</p> Signup and view all the answers

    Which electron carrier is found in Complex III of the electron transport chain?

    <p>Cyt bH</p> Signup and view all the answers

    What is the main function of Complex I in the electron transport chain?

    <p>Pumps 2H+ out of the mitochondrial matrix</p> Signup and view all the answers

    Which poison acts on ATP synthase in the electron transport chain?

    <p>Antimycin A1</p> Signup and view all the answers

    What is the function of Complex III in the electron transport chain?

    <p>Transferring electrons to cytochrome c</p> Signup and view all the answers

    What is the role of Ubiquinone in the Q Pool Defined?

    <p>Containing oxidized and reduced forms in the mitochondrial membrane</p> Signup and view all the answers

    Why is cytochrome c referred to as a soluble electron carrier?

    <p>It can move freely between complexes in the electron transport chain</p> Signup and view all the answers

    What differentiates QH2 from cytochrome c in terms of electron carriers?

    <p>QH2 carries only one electron while cytochrome c carries two electrons</p> Signup and view all the answers

    What is the primary function of Complex IV in electron transport?

    <p>Reducing O2 to H2O</p> Signup and view all the answers

    Which component of the electron transport chain involves Fe and Cu as electron carriers?

    <p>Complex IV</p> Signup and view all the answers

    'Q Cycle and Electron Transport' addresses which significant issue faced by the electron transport chain?

    <p>Leakiness of the electron transport chain</p> Signup and view all the answers

    What is the main responsibility of ATP synthase?

    <p>Producing ATP</p> Signup and view all the answers

    Which complex of ATP synthase contains multiple subunits?

    <p>F1 complex</p> Signup and view all the answers

    What rotates in the F0 complex of ATP synthase as protons move between subunits?

    <p>c subunit</p> Signup and view all the answers

    What forces conformational changes in the F1 complex of ATP synthase?

    <p>Spinning shaft</p> Signup and view all the answers

    Which part of ATP synthase is turned by protons moving through the F0 complex?

    <p>$ ext{γ subunit}$</p> Signup and view all the answers

    What is the electrochemical potential derived from the uneven distribution of electrons across the inner mitochondrial matrix called?

    <p>$ ext{Proton Motive Force}$</p> Signup and view all the answers

    Which enzyme is primarily responsible for producing ATP from ADP and Pi?

    <p>$ ext{ATP Synthase}$</p> Signup and view all the answers

    In which complex do protons move between a and b subunits?

    <p>$ ext{F0}$ complex</p> Signup and view all the answers

    What occurs to form ATP in ATP Synthase?

    <p>$ ext{Binding of ADP and Pi}$</p> Signup and view all the answers

    What type of catalysis does ATP Synthase exhibit during rotation?

    <p>$ ext{Rotational}$</p> Signup and view all the answers

    Match the following components with their roles in the electron transport chain:

    <p>Complex III = Transfer electrons from coenzyme Q to cytochrome c Cytochrome c = Shuttles electrons between Complex III and Complex IV Complex IV = Transfers electrons from cytochrome c to oxygen Coenzyme Q = Accepts electrons from Complex I and Complex II</p> Signup and view all the answers

    Match the following TCA cycle intermediates with their specific roles:

    <p>Citrate = Formed from condensation of oxaloacetate and acetyl-CoA Isocitrate = Undergoes oxidative decarboxylation to form alpha-ketoglutarate Succinyl-CoA = Generates GTP through substrate-level phosphorylation Malate = Converted to oxaloacetate in the last step of the cycle</p> Signup and view all the answers

    Match the following processes with their outcomes in oxidative phosphorylation:

    <p>Proton pumping by Complex I = Contributes to establishing the proton gradient across the inner mitochondrial membrane ATP synthase activity = Converts the proton gradient into ATP production Oxygen consumption at Complex IV = Forms water as a byproduct Electron transfer through Complex II = Contributes electrons directly to the electron transport chain</p> Signup and view all the answers

    Match the following terms with their descriptions related to electron transport chain regulation:

    <p>Allosteric regulation of dehydrogenases by NADH = Inhibits energy production when NADH levels are high Anaplerotic reactions = Replenish citric acid cycle intermediates to maintain metabolic flux Regulation based on substrate availability = Increased substrates enhance pathway flux Role of Ca2+ as an allosteric regulator = Impacts mitochondrial function under varying calcium levels</p> Signup and view all the answers

    Match the following molecules with their contributions to electron transfer in oxidative phosphorylation:

    <p>FADH2 = Donates electrons directly to the electron transport chain at Complex II NADH = Supplies electrons to Complex I, initiating the electron flow Cytochrome c = Transfers electrons between Complexes III and IV Ubiquinone (Coenzyme Q) = Accepts electrons from both Complex I and Complex II</p> Signup and view all the answers

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