6 Questions
What is the role of the C3d complement protein fragment?
It enhances B cell responses against microbes by binding to the CR2 receptor
What is the correct chronological order of events in B cell activation and differentiation?
- Proliferation, 2. Differentiation, 3. Isotype switching, 4. Affinity maturation
Which membrane-bound antibodies do naive B cells express?
IgM and IgD
What type of response occurs when polysaccharide antigens activate marginal zone B cells?
T cell-independent antibody response
Which statement about the complement system is correct?
It is part of the innate immune response
What is the role of the BCR (B cell receptor) in B cell activation?
It recognizes microbial antigens and initiates signaling cascades
Test your knowledge on complement protein C3d, which enhances the antigen-dependent response by enhancing tyrosine phosphorylation of ITAMS. Learn about its role in the innate immune response, its interaction with B lymphocytes through the complement receptor type 2 (CR2), and how B cells recognize antigens via the CR2 receptor.
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