Immunodeficiency Quiz
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Questions and Answers

Which component of innate immunity is affected in chronic granulomatous disease (CGD)?

  • Macrophages
  • T cells
  • Complement system
  • Phagocytes (correct)

Which type of infections are most common in CGD patients?

  • Parasitic infections
  • Fungal infections (correct)
  • Bacterial infections
  • Viral infections

Which genetic mutation causes X-linked CGD?

  • Mutation in a gene on the Y chromosome
  • Mutation in a gene on the X chromosome (correct)
  • Mutation in a subunit of the NADPH oxidase
  • Mutation in a gene on the Z chromosome

Which complement protein deficiency may result in increased bacterial or viral infection or increased incidence of systemic lupus erythematosus?

<p>C4 (C)</p> Signup and view all the answers

Which complement protein deficiency may result in severe infections and may be fatal?

<p>C3 (D)</p> Signup and view all the answers

Which immunodeficiency disease affects phagocytes and natural killer (NK) cells, leading to increased susceptibility to bacterial infection?

<p>Chédiak-Higashi syndrome (B)</p> Signup and view all the answers

Which signaling molecule is associated with severe bacterial (most often pneumococcal) pneumonias when mutated?

<p>MyD88 (A)</p> Signup and view all the answers

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