7 Questions
Which component of innate immunity is affected in chronic granulomatous disease (CGD)?
Phagocytes
Which type of infections are most common in CGD patients?
Fungal infections
Which genetic mutation causes X-linked CGD?
Mutation in a gene on the X chromosome
Which complement protein deficiency may result in increased bacterial or viral infection or increased incidence of systemic lupus erythematosus?
C4
Which complement protein deficiency may result in severe infections and may be fatal?
C3
Which immunodeficiency disease affects phagocytes and natural killer (NK) cells, leading to increased susceptibility to bacterial infection?
Chédiak-Higashi syndrome
Which signaling molecule is associated with severe bacterial (most often pneumococcal) pneumonias when mutated?
MyD88
Test your knowledge on immunodeficiency by taking this quiz on abnormalities in phagocytes and the complement system. Learn about chronic granulomatous disease (CGD) caused by mutations in genes encoding subunits of the enzyme phagocyte NADPH oxidase. Challenge yourself and expand your understanding of immunodeficiency.
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