Collagen Synthesis & Modifications
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Questions and Answers

Which step occurs after the synthesis of pre-pro α chain with a signal sequence?

  • Rapid cleavage of signal sequence in the ER (correct)
  • Hydroxylation and glycosylation
  • Secretion into the extracellular matrix
  • Assembly into a triple helical structure

    • What is the role of molecular chaperones and enzymes in collagen assembly?

  • Facilitation of triple helical structure assembly (correct)
  • Rapid cleavage of signal sequence in the ER
  • Assembly into a triple helical structure
  • Hydroxylation and glycosylation

    • What modifications do the collagen chains undergo after translation?

  • Hydroxylation and glycosylation (correct)
  • Synthesis of pre-pro α chain with a signal sequence
  • Assembly into a triple helical structure
  • Secretion into the extracellular matrix

    • Which step occurs after the signal sequence is rapidly cleaved in the ER?

    <p>Collagen chains undergo essential modifications</p> Signup and view all the answers

    What is the role of molecular chaperones and enzymes in collagen assembly?

    <p>Facilitating the assembly of collagen chains into a triple helical structure</p> Signup and view all the answers

    What is the function of collagen in the extracellular matrix?

    <p>Providing structural support to various tissues</p> Signup and view all the answers

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