12 Questions
Which organelle is involved in the synthesis of the pre-pro α chain?
Endoplasmic reticulum
What happens to the signal sequence during the synthesis of the pre-pro α chain?
It is cleaved in the ER
What is the role of collagen in the extracellular matrix?
To form a strong and flexible network
Which enzyme is responsible for the formation of cross-links in extracellular matrix proteins?
Lysyl oxidase
What is the role of lysyl oxidase in collagen fibril formation?
It catalyzes the conversion of lysine residues into allysine
How are adjacent tropocollagen molecules arranged in the fibrillar array?
In a staggered pattern
Which enzyme is responsible for the formation of cross-links in collagen fibrils?
Lysyl oxidase
How are adjacent tropocollagen molecules arranged in the fibrillar array?
In an overlapping, parallel pattern
What is the role of lysyl oxidase in collagen fibril formation?
To catalyze the conversion of lysine residues into aldehydes
Which type of array do individual tropocollagen molecules form?
Staggered array
What is the role of lysyl oxidase in collagen fibril formation?
It forms cross-links in extracellular matrix proteins
What is the function of allysine in collagen fibrils?
It catalyzes the conversion of lysine residues into allysine
Test your knowledge on the synthesis of pre-pro α chain and the essential modifications collagen chains undergo in this quiz. Learn about the steps involved in ribosome-mediated synthesis, the role of the signal sequence, and the modifications that enhance stability.
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