Acute Coronary Syndromes Quiz

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which modifiable risk factor can lead to increased arterial shear stress and plaque rupture?

  • Diabetes Mellitus
  • Hypertension (correct)
  • Obesity
  • Poor Diet

What is a primary cause of myocardial infarction?

  • Complete occlusion of coronary artery
  • Oxygen starvation
  • Thrombus formation (correct)
  • Myocardial ischemia

Which of the following factors is NOT considered a modifiable risk factor for myocardial infarction?

  • Poor Diet
  • Dyslipidemia
  • Age (correct)
  • Smoking

What effect does diabetes mellitus have on the risk of myocardial infarction?

<p>Promotes endothelial dysfunction (D)</p> Signup and view all the answers

Which group has a higher predisposition to myocardial infarction, according to ethnicity?

<p>Native Americans (B)</p> Signup and view all the answers

In terms of risk factors for acute coronary syndrome (ACS), which of the following is true?

<p>Sedentary lifestyle contributes to metabolic syndrome (A)</p> Signup and view all the answers

Which population is generally at a higher risk of myocardial infarction before menopause?

<p>Males (D)</p> Signup and view all the answers

What is one consequence of a complete occlusion in the coronary artery?

<p>Ischemia leading to necrosis (A)</p> Signup and view all the answers

What is a primary cause of Acute Coronary Syndrome?

<p>Rupture of atherosclerotic plaque (D)</p> Signup and view all the answers

Which of the following is NOT considered a risk factor for Acute Coronary Syndrome?

<p>High levels of HDL cholesterol (C)</p> Signup and view all the answers

What initiates the thrombotic process in Acute Coronary Syndrome?

<p>Exposure of subendothelial proteins (A)</p> Signup and view all the answers

What is a consequence of prolonged myocardial ischemia?

<p>Myocardial infarction (D)</p> Signup and view all the answers

How does smoking contribute to the development of Acute Coronary Syndrome?

<p>By increasing oxidative stress and reducing nitric oxide (B)</p> Signup and view all the answers

Which process follows the rupture of an atherosclerotic plaque in the context of Acute Coronary Syndrome?

<p>Platelet aggregation and thrombus formation (A)</p> Signup and view all the answers

Which factor is NOT a non-modifiable risk factor for coronary artery disease (CAD)?

<p>Smoking habits (D)</p> Signup and view all the answers

What happens when a thrombus completely occludes a coronary artery?

<p>Subsequent myocardial ischemia and infarction (C)</p> Signup and view all the answers

How does atherosclerotic plaque rupture lead to a myocardial infarction?

<p>It exposes subendothelial collagen triggering platelet activation. (C)</p> Signup and view all the answers

Acute Coronary Syndrome is characterized by a spectrum that includes which of the following?

<p>Unstable angina, NSTEMI, and STEMI (C)</p> Signup and view all the answers

What happens to the heart muscle cells during myocardial necrosis?

<p>They die and are replaced by fibrous scar tissue. (B)</p> Signup and view all the answers

What effect does persistent ischemia have on the heart muscle?

<p>It leads to tissue death (necrosis). (C)</p> Signup and view all the answers

Which group is associated with a higher risk for cardiovascular disease?

<p>Individuals with a family history of CAD (A), Postmenopausal women (B)</p> Signup and view all the answers

What is one consequence of coronary artery occlusion due to thrombus formation?

<p>Lack of oxygen leading to myocardial ischemia (B)</p> Signup and view all the answers

What is a characteristic of the scar tissue that replaces infarcted heart cells?

<p>It is non-contractile and fibrous. (C)</p> Signup and view all the answers

Flashcards

Central obesity

A condition characterized by excess body fat around the abdomen, linked to increased risk of heart disease.

Metabolic syndrome

A cluster of health problems increasing the risk of heart disease, including high blood pressure, high blood sugar, and high cholesterol.

Saturated and trans fats

A type of fat that raises bad cholesterol (LDL) levels, increasing heart disease risk.

Myocardial infarction (MI)

A heart attack, caused by prolonged blockage of blood flow to a part of the heart muscle, leading to cell death.

Signup and view all the flashcards

Atherosclerosis

A buildup of plaque in the coronary arteries, which can rupture and trigger a heart attack.

Signup and view all the flashcards

Platelet aggregation

The process by which platelets clump together at the site of a ruptured plaque, forming a blood clot that can block blood flow.

Signup and view all the flashcards

Thrombus formation

The formation of a blood clot that blocks an artery, leading to a heart attack.

Signup and view all the flashcards

Myocardial necrosis

The death of heart muscle cells due to lack of oxygen caused by a blocked coronary artery.

Signup and view all the flashcards

What is Acute Coronary Syndrome (ACS)?

A group of heart conditions caused by a sudden decrease in blood flow to the heart, including Unstable Angina, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI), and ST-Segment Elevation Myocardial Infarction (STEMI).

Signup and view all the flashcards

What is the most likely cause of Acute Coronary Syndrome (ACS)?

The most common cause is the rupture of a plaque in a coronary artery, leading to the formation of a blood clot (thrombus).

Signup and view all the flashcards

What is atherosclerosis in relation to ACS?

This refers to the buildup of cholesterol and other fatty substances inside the arteries, creating plaques that can rupture and block blood flow.

Signup and view all the flashcards

Describe the process of plaque rupture in ACS.

A thin fibrous cap surrounding a plaque ruptures, releasing lipid-rich material into the bloodstream, which triggers platelets to stick together and form a clot.

Signup and view all the flashcards

How does a thrombus form in ACS?

The coagulation cascade is activated, leading to the formation of a fibrin network, which strengthens and stabilizes the growing clot.

Signup and view all the flashcards

What happens when a thrombus occludes a coronary artery during ACS?

The partial or complete blockage of coronary blood flow causes the heart muscle to be deprived of oxygen, leading to ischemia.

Signup and view all the flashcards

What is myocardial infarction in relation to ACS?

Persistent ischemia can lead to the death of the heart muscle, also known as heart attack.

Signup and view all the flashcards

Is Acute Coronary Syndrome (ACS) transmissible? Explain.

ACS is caused by atherosclerosis, a process that does not involve an infectious agent. Therefore, it is not transmissible.

Signup and view all the flashcards

What is a Myocardial Infarction (MI)?

A heart attack occurs when a part of the heart muscle is damaged or dies due to a lack of blood flow. This is usually caused by a blood clot blocking a coronary artery, which supplies blood to the heart.

Signup and view all the flashcards

What are the risk factors for MI?

Risk factors for MI are conditions or habits that increase your chances of having a heart attack. They can be modified (changed) by lifestyle adjustments or non-modifiable (unchangeable) due to genetics or aging.

Signup and view all the flashcards

How does hypertension contribute to MI?

High blood pressure puts extra strain on your arteries, making them more likely to rupture and cause blood clots. This increases the risk of a heart attack.

Signup and view all the flashcards

How does dyslipidemia contribute to MI?

High LDL cholesterol (bad cholesterol) builds up in your arteries, forming plaque. This plaque can rupture, trigger a blood clot, and block blood flow to the heart.

Signup and view all the flashcards

How does smoking contribute to MI?

Smoking damages blood vessels, increases blood clotting, and lowers oxygen levels in your blood, significantly increasing the risk of a heart attack.

Signup and view all the flashcards

How does diabetes contribute to MI?

Diabetes increases the risk of heart attacks by causing damage to blood vessels and negatively affecting blood sugar regulation.

Signup and view all the flashcards

How does obesity contribute to MI?

Obesity increases the risk of metabolic syndrome, a cluster of conditions including high blood pressure, high cholesterol, and insulin resistance, all of which heighten the risk of a heart attack.

Signup and view all the flashcards

How does physical inactivity contribute to MI?

Lack of physical activity increases the risk of developing several conditions such as obesity, diabetes, and high blood pressure, all of which contribute to heart attacks.

Signup and view all the flashcards

Study Notes

Acute Coronary Syndrome (ACS) and Myocardial Infarction

  • ACS: A spectrum of conditions caused by sudden reduction in blood flow to the heart. Includes Unstable Angina (UA), Non-ST-Segment Elevation Myocardial Infarction (NSTEMI), and ST-Segment Elevation Myocardial Infarction (STEMI).
  • Most Likely Cause of ACS: Rupture or erosion of atherosclerotic plaque in a coronary artery, leading to coronary thrombus formation.
  • Pathophysiology of Plaque Rupture/Erosion:
    • Thin fibrous caps of plaques rupture due to shear stress.
    • Lipid-rich material is released into bloodstream, triggering platelet adhesion, activation, and aggregation.
  • Thrombus Formation:
    • Platelets aggregate to form a platelet plug.
    • Coagulation cascade leads to fibrin deposition, stabilizing the thrombus.
  • Reduced Blood Flow and Ischemia:
    • Thrombus partially or completely occludes artery.
    • Reduced coronary blood flow leads to myocardial ischemia (oxygen starvation).
    • Prolonged ischemia results in myocardial infarction (heart attack).
  • Disease Transmission: Not transmissible. Caused by atherosclerosis, plaque rupture, and thrombus formation.
  • Modifiable Risk Factors for ACS: Hypertension, Dyslipidemia, Smoking, Diabetes, Obesity, Physical Inactivity, and Poor Diet.

Myocardial Infarction (MI)

  • MI: Heart attack, occurs when blood flow to part of heart muscle is blocked for an extended period (tissue death/necrosis).
  • Most Likely Cause of MI: Complete occlusion of a coronary artery due to a thrombus, following plaque rupture, or thromboembolism from a plaque rupture in coronary artery.
  • Pathophysiology of MI
    • Plaque rupture or erosion exposes subendothelial collagen and tissue factor.
    • Platelets release thromboxane A2, promoting vasoconstriction and platelet aggregation.
    • Coagulation cascade leads to fibrin formation, creating a thrombus.
    • Complete occlusion of coronary artery stops blood flow.
    • Lack of oxygen causes myocardial ischemia then necrosis of cardiac muscle cells within minutes.
  • Disease Transmission: Not transmissible. Caused by internal processes.
  • Non-Modifiable Risk Factors for MI: Age, Sex, Family history, and Ethnicity.
  • Modifiable Risk Factors for MI: Same as risk factors for ACS.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team
Use Quizgecko on...
Browser
Browser