Introduction to Acute Coronary Syndrome

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56 Questions

What is the cardiac-specific isoenzyme that increases when there has been damage to cardiac cells?

CK-MB

Which biomarker remains elevated for a long period, often as long as 2 weeks, and can be used to detect recent myocardial damage?

Troponin T

What protein found in myocardial cells regulates the myocardial contractile process?

Troponin

What is used to evaluate ventricular function and can assist in diagnosing an MI, especially when the ECG is nondiagnostic?

Echocardiogram

Which enzyme level starts to increase within 1 to 3 hours after the onset of symptoms and peaks within 12 hours?

Myoglobin

What are used to diagnose an acute MI based on the release of cellular contents into the circulation when myocardial cells die?

Cardiac enzymes and biomarkers

What is the preferred term for coronary occlusion and myocardial infarction?

Myocardial infarction

Which condition includes reduced blood flow in a coronary artery, often due to rupture of an atherosclerotic plaque?

Unstable angina

What can result in chest pain and other symptoms that may be referred to as preinfarction angina?

Unstable angina

What results in complete occlusion of a coronary artery, leading to ischemia and necrosis of the myocardium?

Myocardial infarction

Which term is used synonymously with coronary occlusion and heart attack?

Myocardial infarction

What situation can result in chest pain and other symptoms that may be referred to as preinfarction angina?

Unstable angina

When does a clot begin to form on top of the coronary lesion but the artery is not completely occluded?

Unstable angina

What results in vasospasm (sudden constriction or narrowing) of a coronary artery?

Acute blood loss

What leads to decreased oxygen supply in the context of acute coronary syndrome?

Low blood pressure

What may result in chest pain and other symptoms that can be referred to as preinfarction angina?

Unstable angina

What condition results in necrosis of the myocardium supplied by a specific artery due to complete occlusion of the artery?

Myocardial infarction

What leads to increased demand for oxygen in the context of acute coronary syndrome?

Myocardial infarction

What is the main presenting symptom in most patients with acute coronary syndrome?

Chest pain

What do the signs and symptoms of MI, caused by stimulation of the sympathetic nervous system, include?

Cool, pale, and moist skin

What diagnostic tool provides information to assist in ruling out or diagnosing an acute MI?

12-lead ECG

What is a key diagnostic indicator for STEMI (ST-elevation myocardial infarction)?

ST-segment elevation

What do abnormal Q waves on an ECG indicate?

Necrotic tissue

How is NSTEMI (non-ST elevation myocardial infarction) diagnosed?

By blood levels of cardiac biomarkers

What is the first ECG indicator to return to normal during recovery from an MI?

ST-segment elevation

What differentiates NSTEMI from STEMI?

Elevated troponin levels without definite ECG evidence of acute MI

What causes the ST segment to rise at least 1 mm above the isoelectric line on an ECG during an acute MI?

Delayed myocardial repolarization

Which term refers to the differentiation between NSTEMI and STEMI based on diagnostic tests?

Acute coronary syndrome

What is the main goal of medical therapy for patients with acute coronary syndrome?

To prevent or minimize myocardial tissue death

What may be present during an MI without persistent ST elevation or other ECG changes?

Abnormal Q wave without ST-segment and T-wave changes

What is the preferred term for an emergent situation characterized by an acute onset of myocardial ischemia that can lead to myocardial death?

Myocardial infarction (MI)

What condition involves reduced blood flow in a coronary artery, often due to rupture of an atherosclerotic plaque, and may result in chest pain and other symptoms known as preinfarction angina?

Unstable angina

What occurs when plaque rupture and subsequent thrombus formation result in complete occlusion of a coronary artery, leading to ischemia and necrosis of the myocardium supplied by that artery?

Myocardial infarction (MI)

What is the term used to describe the spectrum of Acute Coronary Syndrome which includes unstable angina, NSTEMI, and STEMI?

Acute Coronary Syndrome (ACS)

Which condition involves sudden constriction or narrowing of a coronary artery and may lead to decreased oxygen supply, resulting in myocardial ischemia?

Vasospasm of a coronary artery

What type of situation results in reduced blood flow in a coronary artery, often due to rupture of an atherosclerotic plaque, but without complete occlusion of the artery?

Unstable angina

In which condition does a clot begin to form on top of the coronary lesion but the artery is not completely occluded?

Unstable angina

Which protein found in myocardial cells is specific for cardiac muscle and recognized as a reliable marker of myocardial injury?

Troponin T

What enzyme is a cardiac-specific isoenzyme found mainly in cardiac cells and increases when there has been damage to these cells?

CK-MB

Which enzyme level starts to increase within a few hours during acute MI and remains elevated for a long period, often as long as 2 weeks?

Troponin I

What diagnostic tool can be used to evaluate ventricular function and assist in diagnosing an MI, especially when the ECG is nondiagnostic?

Echocardiogram

What is the preferred term for coronary occlusion and heart attack?

MI (myocardial infarction)

Which condition results in necrosis of the myocardium supplied by a specific artery due to complete occlusion of the artery?

STEMI

What may be used to rule out an acute MI if negative results are obtained?

Elevated myoglobin level

When does myoglobin level start to increase after the onset of symptoms and when does it peak?

Starts within 1 to 3 hours and peaks within 12 hours

What can detect hypokinetic and akinetic wall motion and determine the ejection fraction?

Echocardiogram

What is the main presenting symptom in most patients with acute coronary syndrome?

Chest pain that occurs suddenly and continues despite rest and medication

What are the ECG changes that occur with an MI?

T-wave inversion, ST-segment elevation, and development of an abnormal Q wave

Which biomarker remains elevated for a long period, often as long as 2 weeks, and can be used to detect recent myocardial damage?

Troponin

What is the preferred term for coronary occlusion and myocardial infarction?

Heart attack

What may result in chest pain and other symptoms that can be referred to as preinfarction angina?

All of the above

What condition results in necrosis of the myocardium supplied by a specific artery due to complete occlusion of the artery?

STEMI

Which term refers to the differentiation between NSTEMI and STEMI based on diagnostic tests?

12-lead ECG

What enzyme level starts to increase within 1 to 3 hours after the onset of symptoms and peaks within 12 hours?

CK-MB

What results in complete occlusion of a coronary artery, leading to ischemia and necrosis of the myocardium?

Heart attack

What is used to evaluate ventricular function and can assist in diagnosing an MI, especially when the ECG is nondiagnostic?

Echocardiography

This quiz provides an introduction to acute coronary syndrome (ACS), covering its emergent nature, the spectrum of ACS including unstable angina, NSTEMI, and ST-segment elevation myocardial infarction, and the importance of prompt interventions to prevent myocardial death.

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