Cardiovascular Disease Overview and Atherosclerosis
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Questions and Answers

What is the most prevalent type of cardiovascular disease in adults?

  • Heart Failure
  • Coronary Artery Disease (correct)
  • Peripheral Vascular Disease
  • Arrhythmia
  • Which of the following substances primarily accumulates in the arterial walls during atherosclerosis?

  • Calcium deposits
  • Cholesterol crystals
  • Lipids and fibrous tissue (correct)
  • Glucose
  • What initiates the inflammatory response that leads to atherosclerosis?

  • Age-related degeneration
  • Injury to the vascular endothelium (correct)
  • High levels of HDL cholesterol
  • Antioxidant deficiency
  • What role do macrophages play in the development of atherosclerosis?

    <p>They become foam cells by ingesting lipids.</p> Signup and view all the answers

    What are fatty streaks in the context of atherosclerosis?

    <p>Early deposits of lipids in the arterial wall.</p> Signup and view all the answers

    Which lifestyle factor is known to initiate the injury that leads to atherosclerosis?

    <p>Smoking</p> Signup and view all the answers

    What is the main consequence of the proliferation of smooth muscle cells in the arterial wall?

    <p>Formation of a fibrous cap over lesions</p> Signup and view all the answers

    Which of the following populations is particularly affected by research into coronary vascular disorders?

    <p>Women, children, and diverse racial and ethnic groups</p> Signup and view all the answers

    What characterizes vulnerable plaque in the context of atherosclerosis?

    <p>It has a thin fibrous cap with ongoing inflammation.</p> Signup and view all the answers

    What results from the obstruction of blood flow due to a ruptured plaque?

    <p>Acute myocardial infarction (MI)</p> Signup and view all the answers

    Where do atherosclerotic lesions most commonly form in coronary arteries?

    <p>At the vessel branches</p> Signup and view all the answers

    What is a primary cause of angina pectoris?

    <p>Coronary atherosclerosis</p> Signup and view all the answers

    Which of the following can decrease blood flow to the heart besides atherosclerosis?

    <p>Myocardial trauma or congenital anomalies</p> Signup and view all the answers

    What condition refers to inadequate blood supply to cardiac muscle cells due to narrowed arteries?

    <p>Ischemia</p> Signup and view all the answers

    What happens to myocardial cells if the supply of blood is severely compromised for an extended period?

    <p>They may undergo irreversible damage and necrosis.</p> Signup and view all the answers

    Which factor does NOT contribute to increasing oxygen demand on the heart?

    <p>Acute blood loss</p> Signup and view all the answers

    Study Notes

    Cardiovascular Disease Overview

    • Cardiovascular disease is the leading cause of death across all racial and ethnic groups.
    • Research aims to identify prevention and treatment strategies for diverse populations affected by cardiac conditions.

    Coronary Artery Disease (CAD)

    • CAD is the most common type of cardiovascular disease in adults.
    • Understanding manifestations and assessment methods is crucial for nurses in managing CAD.

    Coronary Atherosclerosis

    • Atherosclerosis is characterized by abnormal lipid accumulation and fibrous tissue in arterial walls.
    • This condition narrows coronary vessels, reducing blood flow to the myocardium.
    • Atherosclerosis is an inflammatory response to arterial injury, involving changes to structural and biochemical properties of the walls.

    Pathophysiology of Atherosclerosis

    • Begins with fatty streaks in arterial intima, potentially starting in childhood.
    • Genetic and environmental factors influence lesion progression.
    • Arterial injury from factors like smoking and hypertension triggers inflammation.
    • Monocytes (macrophages) are attracted to the site, ingest lipids, and form foam cells that lead to plaque formation.
    • Stable plaques have a thick fibrous cap and resist stress; unstable plaques can rupture and cause thrombus formation.
    • Thrombus may obstruct blood flow, leading to acute coronary syndrome (ACS) and potentially myocardial infarction (MI).
    • Anatomical structure of coronary arteries favors atherosclerotic lesions at branch points.

    Clinical Manifestations of CAD

    • Symptoms depend on the severity of arterial lumen narrowing and thrombus formation.
    • As blood flow diminishes, cardiac muscle suffers from ischemia, leading to chest pain known as angina pectoris.
    • Angina results from significant coronary atherosclerosis and can result in irreversible myocardial damage if blood supply decreases sufficiently or persists over time.

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    Description

    This quiz delves into the critical aspects of cardiovascular diseases, focusing on coronary artery disease and atherosclerosis. It explores the prevalence of these conditions, their pathophysiology, and the importance of prevention and treatment strategies. Knowledge on how these diseases affect diverse populations is also covered.

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