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Questions and Answers
Which of the following correctly describes the flow of blood through the pulmonary circulation?
Which of the following correctly describes the flow of blood through the pulmonary circulation?
What is the primary function of the tunica media in arteries?
What is the primary function of the tunica media in arteries?
Which of the following correctly lists the layers of a blood vessel from the outermost to the innermost?
Which of the following correctly lists the layers of a blood vessel from the outermost to the innermost?
Which statement accurately describes the difference between arteries and veins?
Which statement accurately describes the difference between arteries and veins?
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What is the primary difference between the pulmonary circulation and the systemic circulation?
What is the primary difference between the pulmonary circulation and the systemic circulation?
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What is the primary role of the lymphatic system?
What is the primary role of the lymphatic system?
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Which structure is NOT a primary component of the lymphatic system?
Which structure is NOT a primary component of the lymphatic system?
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Which of the following trunks does NOT have a paired structure in the lymphatic system?
Which of the following trunks does NOT have a paired structure in the lymphatic system?
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What is the role of red bone marrow in the skeletal system?
What is the role of red bone marrow in the skeletal system?
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Which function of blood involves the stabilization of body temperature?
Which function of blood involves the stabilization of body temperature?
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Which lymphatic vessel drains the upper limb?
Which lymphatic vessel drains the upper limb?
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What is primarily transported by lymph?
What is primarily transported by lymph?
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Which type of bone marrow can be converted back into red bone marrow if needed?
Which type of bone marrow can be converted back into red bone marrow if needed?
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What is a significant function of blood related to injury?
What is a significant function of blood related to injury?
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Where is spongy bone primarily found in adults?
Where is spongy bone primarily found in adults?
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Which of the following statements about the role of iron in red blood cell production is incorrect?
Which of the following statements about the role of iron in red blood cell production is incorrect?
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Which of the following conditions is not a microcytic anemia?
Which of the following conditions is not a microcytic anemia?
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Which of the following statements about the role of erythropoietin in red blood cell production is correct?
Which of the following statements about the role of erythropoietin in red blood cell production is correct?
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Which of the following is not a function of platelets?
Which of the following is not a function of platelets?
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Which of the following statements about the coagulation cascade is correct?
Which of the following statements about the coagulation cascade is correct?
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Which of the following is not a natural anticoagulant produced by the body?
Which of the following is not a natural anticoagulant produced by the body?
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Which of the following conditions is characterized by an overproduction of lymphoblasts in the bone marrow?
Which of the following conditions is characterized by an overproduction of lymphoblasts in the bone marrow?
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Which of the following statements accurately describes a difference between plasma and serum?
Which of the following statements accurately describes a difference between plasma and serum?
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Which of the following is not a characteristic of a bacterial infection?
Which of the following is not a characteristic of a bacterial infection?
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Which of the following statements accurately describes the role of B cells in adaptive immunity?
Which of the following statements accurately describes the role of B cells in adaptive immunity?
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Which of the following is not a characteristic of Hodgkin's lymphoma?
Which of the following is not a characteristic of Hodgkin's lymphoma?
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Which of the following statements regarding the regulation of red blood cell production is incorrect?
Which of the following statements regarding the regulation of red blood cell production is incorrect?
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Which of the following statements about the lifespan of different blood cells is incorrect?
Which of the following statements about the lifespan of different blood cells is incorrect?
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Which of the following statements about the different types of leukocytes is incorrect?
Which of the following statements about the different types of leukocytes is incorrect?
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Which of the following statements about the different types of immunoglobulins is incorrect?
Which of the following statements about the different types of immunoglobulins is incorrect?
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Study Notes
Cardiovascular System
- Arteries carry oxygenated blood away from the heart
- Veins carry deoxygenated blood toward the heart
- Capillaries are the only avascular system in the body
- The artery structure consists of tunica adventitia (connective tissue), tunica media (smooth tissue), and tunica intima (vascular endothelium)
- The vein structure consists of tunica adventitia, tunica media, and tunica intima, but veins have a larger lumen
- Pulmonary circulation moves blood from the right ventricle to the lungs, then back to the left atrium
- Systemic circulation moves blood from the left ventricle to the body, then back to the right atrium
- The great vessels include the brachiocephalic, common carotid, subclavian, and descending aorta on the left side.
Lymphatic System
- Lymphatic system returns interstitial fluid to circulation and provides immune protection.
- It transports dietary fats.
- Primary structures of the lymph system include the thymus, red bone marrow, tonsils, and lymph nodes (cervical, axillary, inguinal).
- Spleen filters blood, containing lymphocytes
- MALT is found in the small intestine.
- Lymph flows into lymphatic capillaries, then lymphatic vessels, and eventually into the subclavian veins.
Skeletal System
- Provides protection, support, leverage for movement, and storage for minerals.
- Composed of collagen and calcium phosphate salts.
- Bones store red and yellow bone marrow
- Red marrow produces red blood cells, and yellow marrow is inactive red marrow which can be reactivated if needed.
Blood
- Specialized connective tissue
- Transports substances (nutrients, vitamins, minerals, oxygen, hormones)
- Regulates pH, ions, fluid loss upon injury, defence against toxins and pathogens.
- Regulates body temperature
- Adult males have 5-6 liters of blood and females 4-5 liters
- Blood pH is 7.4
Blood Components
- Plasma components include water, plasma proteins, and other solutes.
- Forme elements in blood include red blood cells, white blood cells, and thrombocytes.
- Red blood cells (erythrocytes) are responsible for oxygen transport (live 120 days); white blood cells (leukocytes) are part of the immune system (live longer); and thrombocytes are involved in clotting.
Hematopoiesis
- Process of blood cell formation.
- Begins with pluripotent hematopoietic stem cells.
- Development follows myeloid or lymphoid lines, depending on the cell type.
- Erythropoietin (EPO) is released by the kidneys in response to low oxygen levels
- This regulates RBC production in the bone marrow
RBC Disorders
- Polycythemia is excess RBCs.
- Anemia is deficiency in RBCs, due to decreased production, increased destruction, or blood loss.
- Deficiency in iron/B12/folate leads to microcytic or macrocytic anemia
Blood Cell Disorders
- Thalassemia: low synthesis of alpha/beta hemoglobin chains
- G6PD deficiency: related to oxidative stress and hemolysis- X-recessive
- Sickle cell disease: autosomal recessive, abnormal hemoglobin causes red blood cells to become rigid and sickle-shaped
- Anemia disorders are related to macrocytic or microcytic cells, along with evidence of haemolysis
WBC Disorders
- Leukopenia: abnormally low WBC count
- Leukocytosis: abnormally high WBC count
- Leukemia and lymphoma are malignancies arising from bone marrow/lymphoid tissue (respectively), resulting in high abnormal white blood cell counts.
Phagocytosis
- Cells engulf microbes and other foreign substances.
- Monocytes mature to macrophages in tissue and also phagocytize.
- Neutrophils also respond immediately.
Lymphocytes
- 20-30% of circulating WBCs
- Include T cells (cell-mediated immunity), B cells (antibody-mediated immunity), and Natural Killer cells.
- Develop in bone marrow, thymus, and lymphoid tissue.
Platelets
- Cell fragments involved in clotting
- Formed in bone marrow from megakaryocytes.
- Release granules with factors needed in clot formation and removal of clots
- Thrombocytosis is excessive platelet production
Clotting Disorders
- Conditions that cause abnormal blood clotting or failure to clot when needed
Endothelial Effects
- Endothelial cells line blood vessels.
- They can prevent blood clotting through smooth surface and protein production
- Damage causes loss of this effect, allowing clotting to occur
Immunity
- Innate immunity provides first-line defence against pathogens (bacteria, viruses, parasites).
- Adaptive immunity develops a specific immune response to pathogens.
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Description
Test your knowledge on the cardiovascular and lymphatic systems, including the structure and function of arteries, veins, and capillaries. Learn about pulmonary and systemic circulation, as well as the key components of the lymphatic system. This quiz is ideal for students studying human anatomy and physiology.