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Questions and Answers
In muscle cells, fermentation produces ____.
In muscle cells, fermentation produces ____.
lactate and NAD+
Which term describes the degree to which an element attracts electrons?
Which term describes the degree to which an element attracts electrons?
Electronegativity
Which terms describe two atoms when they form a bond in which electrons are completely transferred from one atom to the other?
Which terms describe two atoms when they form a bond in which electrons are completely transferred from one atom to the other?
Anion and cation
Which of the following statements is true of the bonds in a water molecule?
Which of the following statements is true of the bonds in a water molecule?
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Which of the following statements is not true of most cellular redox reactions?
Which of the following statements is not true of most cellular redox reactions?
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What kind of bond is formed when lithium and fluorine combine to form lithium fluoride?
What kind of bond is formed when lithium and fluorine combine to form lithium fluoride?
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In the reaction 2H2 + O2 → 2H2O + energy, which molecule is oxidized and what kind of bond is formed?
In the reaction 2H2 + O2 → 2H2O + energy, which molecule is oxidized and what kind of bond is formed?
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Which of the following best describes the main purpose of the combined processes of glycolysis and cellular respiration?
Which of the following best describes the main purpose of the combined processes of glycolysis and cellular respiration?
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In the combined processes of glycolysis and cellular respiration, what is consumed and what is produced?
In the combined processes of glycolysis and cellular respiration, what is consumed and what is produced?
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Among the products of glycolysis, which compounds contain energy that can be used by other biological reactions?
Among the products of glycolysis, which compounds contain energy that can be used by other biological reactions?
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Which of the following describes the process of glycolysis?
Which of the following describes the process of glycolysis?
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How many NADH are produced by glycolysis?
How many NADH are produced by glycolysis?
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In glycolysis, ATP molecules are produced by ____.
In glycolysis, ATP molecules are produced by ____.
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Which of these is NOT a product of glycolysis?
Which of these is NOT a product of glycolysis?
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In glycolysis, what starts the process of glucose oxidation?
In glycolysis, what starts the process of glucose oxidation?
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In glycolysis there is a net gain of _____ ATP.
In glycolysis there is a net gain of _____ ATP.
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In the oxidation of pyruvate to acetyl CoA, one carbon atom is released as CO2. However, the oxidation of the remaining two carbon atoms—in acetate—to CO2 requires a complex, eight-step pathway—the citric acid cycle. Consider four possible explanations for why the last two carbons in acetate are converted to CO2 in a complex cyclic pathway rather than through a simple, linear reaction.
In the oxidation of pyruvate to acetyl CoA, one carbon atom is released as CO2. However, the oxidation of the remaining two carbon atoms—in acetate—to CO2 requires a complex, eight-step pathway—the citric acid cycle. Consider four possible explanations for why the last two carbons in acetate are converted to CO2 in a complex cyclic pathway rather than through a simple, linear reaction.
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What happened to most of the energy that the cell obtains from the oxidation of glucose?
What happened to most of the energy that the cell obtains from the oxidation of glucose?
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Which of these enters the citric acid cycle?
Which of these enters the citric acid cycle?
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In the citric acid cycle, ATP molecules are produced by ____.
In the citric acid cycle, ATP molecules are produced by ____.
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Which of these is NOT a product of the citric acid cycle?
Which of these is NOT a product of the citric acid cycle?
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Which statement about the citric acid cycle is correct?
Which statement about the citric acid cycle is correct?
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The electrons stripped from glucose in cellular respiration end up in which compound?
The electrons stripped from glucose in cellular respiration end up in which compound?
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In mitochondrial electron transport, what is the direct role of O2?
In mitochondrial electron transport, what is the direct role of O2?
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How would anaerobic conditions (when no O2 is present) affect the rate of electron transport and ATP production during oxidative phosphorylation?
How would anaerobic conditions (when no O2 is present) affect the rate of electron transport and ATP production during oxidative phosphorylation?
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Which statement best explains why more ATP is made per molecule of NADH than per molecule of FADH2?
Which statement best explains why more ATP is made per molecule of NADH than per molecule of FADH2?
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Which one of the following statements about the redox reactions of the electron transport chain is correct?
Which one of the following statements about the redox reactions of the electron transport chain is correct?
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In fermentation _____ is reduced and _____ is oxidized.
In fermentation _____ is reduced and _____ is oxidized.
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In the absence of oxygen, what is the net gain of ATP for each glucose molecule that enters glycolysis?
In the absence of oxygen, what is the net gain of ATP for each glucose molecule that enters glycolysis?
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What happens to the carbon in compounds that do not end up as CO2?
What happens to the carbon in compounds that do not end up as CO2?
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What is the oxidizing agent in the following reaction, Pyruvate + NADH + H+ → Lactate + NAD+?
What is the oxidizing agent in the following reaction, Pyruvate + NADH + H+ → Lactate + NAD+?
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The immediate energy source that drives ATP synthesis by ATP synthase during oxidative phosphorylation is the ____.
The immediate energy source that drives ATP synthesis by ATP synthase during oxidative phosphorylation is the ____.
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Which metabolic pathway is common to both fermentation and cellular respiration of a glucose molecule?
Which metabolic pathway is common to both fermentation and cellular respiration of a glucose molecule?
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In mitochondria, exergonic redox reactions provide the energy that establishes the ____.
In mitochondria, exergonic redox reactions provide the energy that establishes the ____.
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The final electron acceptor of the electron transport chain that functions in aerobic oxidative phosphorylation is ____.
The final electron acceptor of the electron transport chain that functions in aerobic oxidative phosphorylation is ____.
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When electrons flow along the electron transport chains of mitochondria, which of the following changes occurs?
When electrons flow along the electron transport chains of mitochondria, which of the following changes occurs?
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Most CO2 from catabolism is released during ____.
Most CO2 from catabolism is released during ____.
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Which of the following statements about the chemiosmotic synthesis of ATP is correct?
Which of the following statements about the chemiosmotic synthesis of ATP is correct?
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The molecule that functions as the reducing agent (electron donor) in a redox or oxidation-reduction reaction ____.
The molecule that functions as the reducing agent (electron donor) in a redox or oxidation-reduction reaction ____.
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Which of the following statements describes the results of this reaction, C6H12O6 + 6 O2 → 6 CO2 + 6 H2O + Energy?
Which of the following statements describes the results of this reaction, C6H12O6 + 6 O2 → 6 CO2 + 6 H2O + Energy?
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When a glucose molecule loses a hydrogen atom as the result of an oxidation-reduction reaction, the molecule becomes ____.
When a glucose molecule loses a hydrogen atom as the result of an oxidation-reduction reaction, the molecule becomes ____.
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Which of the following statements describes NAD+?
Which of the following statements describes NAD+?
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Where does glycolysis take place in eukaryotic cells?
Where does glycolysis take place in eukaryotic cells?
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The oxygen consumed during cellular respiration is involved directly in which process or event?
The oxygen consumed during cellular respiration is involved directly in which process or event?
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Why are carbohydrates and fats considered high energy foods?
Why are carbohydrates and fats considered high energy foods?
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Which process in eukaryotic cells will proceed normally whether oxygen (O2) is present or absent?
Which process in eukaryotic cells will proceed normally whether oxygen (O2) is present or absent?
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What is the term for metabolic pathways that release stored energy by breaking down complex molecules?
What is the term for metabolic pathways that release stored energy by breaking down complex molecules?
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A molecule that is phosphorylated ____.
A molecule that is phosphorylated ____.
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Why is glycolysis described as having an investment phase and a payoff phase?
Why is glycolysis described as having an investment phase and a payoff phase?
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For each molecule of glucose that is metabolized by glycolysis and the citric acid cycle, what is the total number of NADH + FADH2 molecules produced?
For each molecule of glucose that is metabolized by glycolysis and the citric acid cycle, what is the total number of NADH + FADH2 molecules produced?
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Carbon dioxide (CO2) is released during which of the following stages of cellular respiration?
Carbon dioxide (CO2) is released during which of the following stages of cellular respiration?
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How many carbon atoms are fed into the citric acid cycle as a result of the oxidation of one molecule of pyruvate?
How many carbon atoms are fed into the citric acid cycle as a result of the oxidation of one molecule of pyruvate?
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During cellular respiration, acetyl CoA accumulates in which location?
During cellular respiration, acetyl CoA accumulates in which location?
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Energy released by the electron transport chain is used to pump H+ into which location in eukaryotic cells?
Energy released by the electron transport chain is used to pump H+ into which location in eukaryotic cells?
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What is proton-motive force?
What is proton-motive force?
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Approximately how many molecules of ATP are produced from the complete oxidation of two molecules of glucose (C6H12O6) in aerobic cellular respiration?
Approximately how many molecules of ATP are produced from the complete oxidation of two molecules of glucose (C6H12O6) in aerobic cellular respiration?
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Where are the proteins of the electron transport chain located?
Where are the proteins of the electron transport chain located?
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Which of the following produces the most ATP when glucose (C6H12O6) is completely oxidized to carbon dioxide (CO2) and water?
Which of the following produces the most ATP when glucose (C6H12O6) is completely oxidized to carbon dioxide (CO2) and water?
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Where is ATP synthase located in the mitochondrion?
Where is ATP synthase located in the mitochondrion?
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One function of both alcohol fermentation and lactic acid fermentation is to ____.
One function of both alcohol fermentation and lactic acid fermentation is to ____.
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Which of the following normally occurs regardless of whether or not oxygen (O2) is present?
Which of the following normally occurs regardless of whether or not oxygen (O2) is present?
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Which metabolic pathway is common to both cellular respiration and fermentation?
Which metabolic pathway is common to both cellular respiration and fermentation?
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What is the purpose of beta oxidation in respiration?
What is the purpose of beta oxidation in respiration?
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Study Notes
Fermentation in Muscle Cells
- Fermentation in muscle cells produces lactate and regenerates NAD+.
- In anaerobic conditions, pyruvate is reduced while NADH is oxidized.
- Under anaerobic conditions, the net gain of ATP per glucose molecule during glycolysis is two ATP.
Glycolysis Overview
- Glycolysis is the initial stage of glucose oxidation and occurs in the cytosol.
- It starts with ATP investment, using stored ATP to ultimately yield a net gain of two ATP molecules.
- Two NADH are produced as part of the glycolysis process.
- Major products of glycolysis include ATP and pyruvate, which can be used by other biological reactions.
Citric Acid Cycle (Krebs Cycle)
- Acetyl CoA enters the citric acid cycle after the oxidation of pyruvate.
- ATP production in the citric acid cycle occurs through substrate-level phosphorylation.
- The last reaction of the cycle yields a substrate for the first reaction, indicating a cyclic nature.
- Most CO2 produced during cellular respiration originates from the citric acid cycle.
Electron Transport Chain (ETC)
- Electrons from glucose end up in water, with O2 acting as the final electron acceptor.
- The electron transport chain is responsible for establishing a proton gradient in the mitochondrial intermembrane space.
- ATP synthesis driven by the proton-motive force relies on the H+ concentration across the membrane holding ATP synthase.
Redox Reactions and ATP Production
- NAD+ is reduced to NADH in glycolysis, pyruvate oxidation, and the citric acid cycle.
- Fewer protons are pumped across the membrane when FADH2 is the electron donor compared to NADH, resulting in less ATP produced from FADH2.
- In glycolysis and the citric acid cycle, carbon that does not end up as CO2 is used for building blocks in complex molecules.
Energy Flow and Efficiency
- The complete oxidation of one glucose molecule can yield approximately 30-32 ATP, with oxidative phosphorylation accounting for the most ATP production.
- Beta oxidation is a metabolic pathway that breaks down fatty acids for energy.
- Both cellular respiration and fermentation share glycolysis as a common metabolic pathway.
Key Concepts of Cellular Respiration
- Chemiosmosis is the coupling of electron transport with proton movement across a membrane for ATP synthesis.
- ATP synthase is located in the mitochondrial inner membrane, where it utilizes the proton gradient to produce ATP.
- Carbohydrates and fats are high-energy foods due to their high electron content associated with hydrogen.
Miscellaneous
- The overall equation for glucose oxidation showcases glucose being oxidized and oxygen being reduced.
- NADH is seen as an essential reducing agent in metabolic reactions, losing electrons and potential energy during redox processes.
- Acetyl CoA accumulates in the mitochondrial matrix, serving as a significant metabolic intermediate.
Studying That Suits You
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Description
Test your knowledge of key concepts in Campbell's biology textbook, specifically Chapter 9. This quiz covers important terms and definitions related to cellular processes and biochemical concepts. Perfect for students needing a refresher or preparation for exams.