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Questions and Answers
What is the primary function of hemoglobin in red blood cells?
Which type of blood cell is primarily involved in immune response?
What percentage of blood is made up of plasma?
Which component of blood is responsible for clotting?
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Which structure acts as the heart's natural pacemaker?
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What is the primary role of albumins in plasma?
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What percentage of red blood cells are typically found in blood volume?
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During exercise, blood flow is rerouted primarily towards which organs?
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What is the lifespan of an average red blood cell?
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The conducting system of the heart includes all of the following EXCEPT:
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What is the primary role of the sensory division of the nervous system?
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Which of the following accurately describes the autonomic nervous system?
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What is the structure containing a collection of neuron cell bodies outside of the CNS called?
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In which nervous system division do the action potentials travel from the CNS to skeletal muscles?
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Which statement about the enteric nervous system is true?
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What characterizes the sympathetic division of the autonomic nervous system?
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Which aspect distinguishes the somatic nervous system from the autonomic nervous system?
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Where are the cell bodies of the first neuron located in the autonomic nervous system pathway?
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Which division of the nervous system primarily handles voluntary actions?
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What is the role of the autonomic ganglion in the autonomic nervous system?
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What is the primary function of the kidneys?
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Where are the kidneys located in the body?
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What is the role of the renal artery?
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Which structure is part of the renal corpuscle in the nephron?
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What differentiates juxtamedullary nephrons from cortical nephrons?
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What is the function of Bowman's capsule?
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Which layer of Bowman's capsule is composed of podocytes?
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How does the afferent arteriole differ from the efferent arteriole in the nephron?
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What structure directly follows the renal pelvis in the path of urine flow?
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Which characteristic is unique to the loop of Henle compared to other parts of the nephron?
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What structure connects the spinal cord to the rest of the brain?
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Which spinal nerves are responsible for the lower limbs?
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Which meningeal layer is the thickest and most superficial?
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Where are the cell bodies of motor neurons located within the spinal cord?
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What is the main function of the medulla oblongata?
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Which type of response is generally faster, a reflex or a voluntary reaction?
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What is the function of the cerebrospinal fluid within the meninges?
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Which part of the brain is responsible for regulating rapid eye movement during sleep?
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How many pairs of spinal nerves emerge from the spinal cord?
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The outer layer of the spinal nerves is called:
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What is the cauda equina?
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Which structure is primarily responsible for coordinating locomotion?
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Which type of reflex involves the contraction of skeletal muscles?
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What type of neuron carries sensory information into the spinal cord?
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Which layer of the meninges sits directly over the brain and cannot be removed?
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What is the primary role of cerebrospinal fluid?
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Which of the following statements about cranial nerves is correct?
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What characterizes the sympathetic nervous system?
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Where are the cell bodies of the parasympathetic nervous system located?
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What is a structural difference between the somatic and autonomic nervous systems?
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Which effect does the parasympathetic division have on the digestive tract?
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How does the autonomic nervous system primarily regulate its functions?
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What does the term 'dual innervation' refer to?
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What type of fluid primarily lines the brain's ventricles?
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Which cranial nerve function includes a combination of sensory, somatic, and parasympathetic functions?
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Which function is typically managed by the sympathetic nervous system?
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What is the primary function of ependymal cells in the brain?
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Which of the following is true regarding the actions of the parasympathetic division?
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Study Notes
Cardiovascular Response to Exercise
- Blood pressure increases during exercise due to redirected blood flow towards the brain and cardiac muscles.
- Hormonal control includes epinephrine (adrenaline), which increases heart rate and stroke volume through vasoconstriction in response to stress.
Cardiac Conducting System
- Comprises an internal pacemaker and nerve pathways throughout the myocardium.
- Action potentials generate rapid changes in membrane potential, serving as electrical signals that stimulate cardiac muscle contractions.
- The heart has the ability to generate its own action potentials demonstrating auto-rhythmicity.
- Key components include:
- Sinoatrial (SA) node: primary pacemaker located in the atrial wall producing regular action potentials.
- Atrioventricular (AV) node: located at the junction of the atrium and ventricle.
- Atrioventricular bundle and branches: conduct impulses from the AV node to the ventricular walls via Purkinje fibers.
Blood Composition
- Blood is a life-sustaining fluid, vital for disease diagnosis and composed of:
- Plasma (55%): Mostly water (91%), proteins (7% including albumins, globulins, and fibrinogen), and other solutes (2%).
- Buffy coat: Contains white blood cells and platelets.
- Formed elements (45%): Red blood cells possess a haematocrit value, indicating the proportion of blood that is cellular.
- Average blood volume is 5-6 liters in males and 4-5 liters in females, with blood pH ranging from 7.35 to 7.45.
Blood Cells
- Erythrocytes (Red Blood Cells):
- Biconcave shape (7.5µm) without nucleus or organelles, providing a large surface area for oxygen transport.
- Contain hemoglobin, which carries 98.5% oxygen and facilitates carbon dioxide transport.
- Leukocytes (White Blood Cells):
- Complete cells that indicate infection when their count is elevated.
- Various types exist, contributing to the immune response.
Renal System Anatomy
- Consists of:
- Kidneys: urine formation.
- Ureters: urine passage.
- Urinary bladder: urine storage.
- Urethra: urine expulsion.
- Renal capsule surrounds each kidney, supported by adipose tissue and renal fascia.
Kidney Location and Anatomy
- Kidneys lie posterior to the parietal peritoneum, with the right kidney slightly lower due to the liver.
- Each kidney measures approximately 11cm long and 5cm wide, weighing around 130g.
- The hilum serves as the entry and exit point for blood vessels and nerves.
Internal Anatomy of the Kidney
- Organized into two key regions:
- Outer cortex and inner medulla.
- Urine flows through nephrons, the functional units of the kidney comprising various structures including the renal corpuscle.
Types of Nephrons
- Approximately 1.3 million nephrons per kidney:
- Juxtamedullary nephrons (15%): Deep cortical location with long loops of Henle.
- Cortical nephrons (85%): Located near the cortex with shorter loops.
Renal Corpuscle
- Includes the glomerulus (capillary network) and Bowman's capsule (filtering chamber).
- Blood filtration occurs here, with higher pressure in afferent arterioles compared to efferent arterioles aiding in this process.
Bowman's Capsule and Filtration Membrane
- Parietal layer: Simple squamous epithelium transitioning to cuboidal epithelium in the proximal convoluted tubule.
- Visceral layer: Composed of podocytes surrounding the glomerular capillaries, essential for filtration.
Nervous System Overview
- Divided into central (CNS) and peripheral (PNS) systems, which communicate through sensory and motor outputs.
- PNS further divides into somatic (voluntary control of skeletal muscles) and autonomic (involuntary control of smooth and cardiac muscles).
Autonomic Nervous System
- Sympathetic division: Responsible for "fight or flight" responses; arises from the thoraco-lumbar region.
- Prepares the body for action in stressful situations and works in conjunction with the parasympathetic division for homeostasis.
Enteric Nervous System
- Nerve plexus within the digestive tract managing sensory information and motor functions related to digestion.
Sensory and Motor Division
- Sensory (afferent) division detects stimuli and transmits signals to the CNS.
- Motor (efferent) division transmits signals from the CNS to muscles and glands for physiological responses.### Reflexes
- Knee jerk, Golgi tendon, Babinski, and pupillary reflexes are examples of reflexes.
- Reflexes are quick, involuntary responses to stimuli requiring no brain involvement.
- Reactions are voluntary, slower, and involve the brain and spinal cord.
- Reaction time can improve with practice, demonstrated through actions like catching a ball.
Spinal Cord Overview
- The spinal cord runs from the foramen magnum to the first or second lumbar vertebrae.
- Split into cervical, thoracic, lumbar, sacral, and coccygeal regions.
- Comprises 31 pairs of spinal nerves; configured as follows:
- Cervical: 8 pairs
- Thoracic: 12 pairs
- Lumbar: 5 pairs
- Sacral: 5 pairs
- Coccygeal: 1 pair
- Enlargements in the cervical and lumbar regions correspond to upper and lower limbs.
Anatomy of Meninges
- Meninges protect the CNS and encompass the brain and spinal cord.
- Dura mater is the tough, outer layer with a subdural space for serous fluid.
- Arachnoid mater features a web-like structure with a subarachnoid space containing CSF and blood vessels.
- Pia mater is the delicate, innermost layer enveloping the CNS and rich in blood vessels.
Spinal Cord Structure
- White matter is organized into dorsal, ventral, anterior, and lateral columns.
- Grey matter has posterior, lateral, and anterior horns.
- Commissures connect left and right sides of grey matter.
- Dorsal roots carry sensory nerves, while ventral roots carry motor nerves.
Neuron Organization
- Autonomic motor neuron cell bodies in the lateral horn; somatic in the grey matter horns.
- Nerve structure consists of:
- Endoneurium surrounding each axon.
- Perineurium encasing nerve fascicles.
- Epineurium encompassing whole nerves.
Nervous System Anatomy
- Sympathetic nerve cell bodies are located between T1 and L2 (thoracolumbar division).
- Parasympathetic cell bodies range from S2 to S4 and in cranial nerve nuclei (craniosacral division).
- Autonomic system involves two neurons: preganglionic and postganglionic.
Brain and Its Structure
- The brain weighs approximately 1.5 kg, consisting of around 100 billion neurons.
- Organized into the forebrain, midbrain, and hindbrain.
- The brainstem (comprised of midbrain, pons, and medulla oblongata) connects the spinal cord and brain.
Brainstem Functions
- Medulla oblongata is crucial for autonomic regulation, controlling heart rate and respiration.
- The pons acts as a bridge for signal conduction and regulates REM sleep.
- Midbrain facilitates reflex movements in response to sensory stimuli.
Cerebellum Characteristics
- Smaller than the cerebrum, with an outer grey matter cortex and inner white matter medulla.
- Coordinates locomotor functions with the cerebrum.
Ventricles and CSF
- The brain has four interconnected ventricles lined with ependymal cells.
- Largest ventricles are the lateral ventricles, connected to the third and fourth ventricles.
- Cerebrospinal fluid (CSF) is primarily produced by the choroid plexus, cushioning the brain and spinal cord.
Cranial Nerves
- Twelve pairs of cranial nerves emerge from the brain, fulfilling sensory and motor roles.
Autonomic Nervous System
- Divided into sympathetic (fight or flight) and parasympathetic (rest and digest) systems.
- Sympathetic activation quickens heart rate, while parasympathetic promotes digestion.
- Both divisions can act on the same organs but in opposing manners.
Regulation of the Autonomic Nervous System
- Functions of the ANS are primarily regulated through reflexes and involve central nervous system centers like the hypothalamus.
- The spinal cord governs reflex activities, while the brain stem oversees heart rate, respiration, and other autonomic functions.
- Higher brain centers, such as the cerebrum and limbic system, modulate ANS responses based on emotional states or thoughts.
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Description
This quiz covers the effects of exercise on blood pressure, including the rerouting of blood flow and hormonal controls such as epinephrine. Understand how the body responds to stress and injury through the cardiac conducting system and its internal pacemaker. Test your knowledge on these critical physiological concepts.