Biosynthesis of Natural Products Judith K. Costantine Lecture Summary

Primary metabolites are closely engaged in the growth, development, and reproduction of an organism.

Biosynthesis is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.

Primary metabolites include sugars, amino acids, and fatty acids.

<p>Natural products are isolated chemical compounds or substances from living organisms.</p> Signup and view all the answers

<p>Students should be able to define biosynthesis, understand basic metabolic pathways, explain biosynthetic pathways for secondary metabolites, and identify starting substrates, intermediate compounds, enzymes, and end products.</p> Signup and view all the answers

<p>The mevalonate pathway is involved in the biosynthesis of isoprenoids and sterols.</p> Signup and view all the answers

<p>Isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)</p> Signup and view all the answers

<p>Acetyl-CoA</p> Signup and view all the answers

<p>Mevalonic acid</p> Signup and view all the answers

<p>3-hydroxy-3methylglutaryl coenzyme A reductase (HMGCoAR)</p> Signup and view all the answers

<p>Geranyl diphosphate (GPP)</p> Signup and view all the answers

<p>The mevalonate pathway</p> Signup and view all the answers

<p>1-deoxy-D-xylulose 5-phosphate pathway</p> Signup and view all the answers

<p>Methylerythritolphosphate</p> Signup and view all the answers

<p>Biosynthesis of aromatic amino acids</p> Signup and view all the answers

<p>Aromatic amino acids, vitamins, proteins, secondary metabolites</p> Signup and view all the answers

<p>Summarize the mevalonate and non-mevalonate pathways</p> Signup and view all the answers

<p>Different metabolic branches in different microorganisms</p> Signup and view all the answers