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Biochemistry LE 6: Amino Acid Metabolism (Biosynthesis of NEAA and Specialized Products)

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38 Questions

What is the abbreviation of Tetrahydrobiopterin?

BH4

Which of the following is an amino acid?

Aspartate

What is the full form of GSH?

Reduced glutathione

What is the name of the cycle mentioned in the text?

Citric Acid Cycle

What is the topic of the Youtube Video mentioned in the text?

Amino Acid Metabolism

What is another name for the abbreviation BH2?

Quinoid dihydrobiopterin

What is the topic of the lecturer mentioned in the text?

Amino Acid Metabolism

What is the enzyme involved in the conversion of pyruvate to alanine?

Alanine aminotransferase (ALT)

What is the cofactor required for the transamination reaction?

PLP

What is the purpose of the glucose-alanine cycle in the liver?

To produce glucose from alanine

What is the source of alanine in the glucose-alanine cycle?

Muscle proteins

What is the role of glutamate in the transamination reaction?

Donates an amino group to pyruvate

What is the purpose of vitamins in the body?

To act as coenzymes

What is the fate of glucose produced in the liver through gluconeogenesis?

It is transported back to the muscle for energy use

What is the characteristic odor of the patient's skin and wet diaper?

Musty

What is the elevated amino acid in the patient's blood?

Phenylalanine

What is the reason for the patient's skin becoming paler?

Decreased melanin production

What is the classification of amino acids that cannot be synthesized by the human body?

Essential amino acids

How many amino acids are classified as essential out of the 21 amino acids?

10

What is the biochemical basis for the therapeutic strategy for the patient?

Reducing phenylalanine intake

Why did the patient's mother waive the newborn screening at birth?

The information is not provided in the scenario

What amino acid pair comprises the energy stores in the skeletal muscles?

Cysteine and serine

Which nucleotide is utilized in the synthesis of high-energy stored compounds?

ATP

What reaction converts the precursor amino acid to the neurotransmitter responsible for urticaria?

Decarboxylation

Which neurotransmitter is given to a patient who developed jet lag?

Melatonin

What is the rate-limiting step in the synthesis of the deficient neurotransmitter in Parkinson’s Disease?

Decarboxylation of DOPA to dopamine

What is the arginine-derived sublingual tablet given to a patient with hypertension and diabetes who developed angina?

Nitroglycerin

Which reaction is the major mechanism of detoxifying ammonia?

Amination of glutamate to glutamine

What is the role of Gabapentin in medical treatment?

Treating epilepsy

What is the potential benefit of Histamine in medical treatment?

Treating urticaria

Why is Serotonin important in medical treatment?

It regulates mood

What is required for the incorporation of oxygen into the -OH group of proline or lysine residue?

Ascorbic acid

What is the effect of ascorbic acid deficiency on collagen synthesis?

Impaired collagen synthesis

What is the role of ferrous ion in the collagen synthesis reaction?

It is oxidized to ferric ion

What is the consequence of ascorbic acid deficiency on wound healing?

Prolonged wound healing

What is the role of ascorbic acid in the body?

It is an antioxidant

What is the effect of ascorbic acid supplementation on patients recovering from surgery or illnesses?

It accelerates wound healing

What is the consequence of ascorbic acid deficiency on connective tissue?

It leads to the degeneration of connective tissue

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