6 Questions
What membrane-bound antibodies do Naïve B cells express?
IgM and IgD
What type of response occurs when polysaccharide antigen activates marginal zone B cells?
T-independent IgM responses
What antibodies are mainly produced when polysaccharide antigen activates marginal zone B cells?
IgM, natural antibodies
What is directly related to the strategy of increasing heavy-chain isotype switching?
Cytokines and CD40L-CD40 interaction
Which cell can present an antigen to a B cell in the lymph node follicle without processing the antigen?
Follicular dendritic cells (FDC)
What process is required for antigen receptor-mediated signal transduction in B cells?
Cross-linking of two or more membrane Ig molecules
Test your knowledge on the membrane-bound antibodies expressed by Naïve B cells and the type of response that occurs when polysaccharide antigens activate marginal zone B cells. Learn about immunoglobulins M and D (IgM and IgD), as well as the role of marginal zone B cells in immune responses.
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