23 Questions
What are the specific areas on the antigen molecule that react with antibodies called?
Antigenic determinants or epitopes
Which type of antigenic determinants are recognized mainly by T cells?
Sequential (or linear) determinants
Which type of antigens are poorly immunogenic?
Nucleic Acids
What is the characteristic of lipid antigens in terms of immunogenicity?
Non-immunogenic
What type of antigens have entered the body from the outside by inhalation, ingestion, or injection?
Exogenous antigens
What are the antigenic determinants that consist of amino acid residues spatially juxtaposed in the folded protein called?
Conformational determinants
How are exogenous antigens mainly taken up by antigen processing cells (APCs)?
By phagocytosis
What are endogenous antigens?
Antigens that are generated within cells
Which of the following is an example of human tissue antigen?
Blood group antigens A, B, and Rh
What is the role of major histocompatibility complex antigens (MHC)?
Presenting antigens to T cells
How can some exogenous antigens transform into endogenous antigens?
Through a process mediated by MHC molecules
Which of the following is NOT a type of antigen according to the text?
Nucleotides
What is the definition of an immunogen based on the text?
A stimulus that generates antibodies
Which term describes substances that become immunogenic by coupling to a larger carrier molecule?
Haptens
What type of antigens can be conjugates of lipids with proteins?
Lipoproteins
Which substances are capable of generating an immune response by themselves?
Immunogens
What does MHC stand for in the context of antigen processing and presentation?
Major Histocompatibility Complex
What is the role of high molecular weight antigens in inducing an immune response?
They require a carrier molecule to act as a complete antigen
Which of the following properties can make molecules more effective antigens?
Having distinctive shapes and novel subunit combinations
What are antigenic determinants also known as?
Epitopes
Why do high molecular weight antigens require carrier molecules to act as complete antigens?
Because they are incomplete antigens by themselves
What is the significance of the route of administration in antigenicity?
Parenteral routes are more immunogenic compared to oral routes
Which type of molecules are less likely to be effective antigens?
Molecules lacking distinctive shapes and novel subunit combinations
Learn about the structure, processing, and presentation of antigens in this presentation by Dr. Muna Oqal. Explore the definition of antigens and epitopes, types and sources of antigens, antigen processing and presentation, and the roles of Major Histocompatibility Complex (MHC) in generating immunity.
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