23 Questions
What is an immunogen?
A stimulus that produces an immune response
Which type of molecule can become immunogenic when coupled with a larger carrier molecule?
Haptens
What is the function of Major Histocompatibility Complex (MHC) in relation to antigens?
Antigen processing and presentation
Which of the following is NOT a type of antigen according to the text?
Globulins
What differentiates an antigen from an immunogen?
Ability to generate an immune response
Which type of molecule can be both an antigen and an immunogen at the same time?
Proteins
What is the term used to describe the small area on the antigen molecule that reacts specifically with antibodies?
Epitope area
Which type of antigenic determinant is recognized mainly by T cells?
Sequential determinants
Which of the following is considered a good immunogen among proteins?
Pure proteins or glycoproteins
What type of antigens have entered the body from the outside by inhalation, ingestion, or injection?
Exogenous antigens
Which type of antigen is non-immunogenic, but may act as haptens?
Lipids
What are sites on or within an antigen with which antibodies react called?
Antigenic determinants
What is the molecular weight range of high molecular weight antigens?
More than 10,000
Which type of molecules are unable to induce an immune response by themselves and require a carrier molecule to act as a complete antigen?
Incomplete antigens
What is another name for antigenic determinants?
Epitopes
Which property makes molecules more effective antigens?
Larger molecular masses between 5000 and 100,000 daltons
What type of routes of administration are more immunogenic compared to the oral route?
Parenteral routes
What is the main characteristic of epitopes?
Immunologically active regions that bind to specific receptors
Which type of cells trap viral antigens in the body?
Macrophages
How are exogenous antigens mainly taken up by APCs?
Phagocytosis
Which of the following is NOT a human tissue antigen?
Rh factor
What is the major histocompatibility complex (MHC) involved in?
Antigen presentation
Which type of infection can lead to the generation of endogenous antigens within cells?
Viral infection
Learn about antigens, epitopes, types and sources of antigens, antigen processing and presentation, and the role of Major Histocompatibility Complex (MHC) in immunity generation. This presentation by Dr. Muna Oqal covers the definitions and functions of antigens in the immune system.
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