Antigen Structure, Processing and Presentation Overview
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Questions and Answers

What is an immunogen?

  • A low molecular weight substance
  • A conjugate of lipids with proteins
  • A foreign substance from the environment
  • A stimulus that produces an immune response (correct)

Which type of molecule can become immunogenic when coupled with a larger carrier molecule?

  • Lipids
  • Proteins
  • Polysaccharides
  • Haptens (correct)

What is the function of Major Histocompatibility Complex (MHC) in relation to antigens?

  • Production of antibodies
  • Formation of antigens
  • Generation of immune response
  • Antigen processing and presentation (correct)

Which of the following is NOT a type of antigen according to the text?

<p>Globulins (C)</p> Signup and view all the answers

What differentiates an antigen from an immunogen?

<p>Ability to generate an immune response (D)</p> Signup and view all the answers

Which type of molecule can be both an antigen and an immunogen at the same time?

<p>Proteins (B)</p> Signup and view all the answers

What is the term used to describe the small area on the antigen molecule that reacts specifically with antibodies?

<p>Epitope area (D)</p> Signup and view all the answers

Which type of antigenic determinant is recognized mainly by T cells?

<p>Sequential determinants (D)</p> Signup and view all the answers

Which of the following is considered a good immunogen among proteins?

<p>Pure proteins or glycoproteins (A)</p> Signup and view all the answers

What type of antigens have entered the body from the outside by inhalation, ingestion, or injection?

<p>Exogenous antigens (A)</p> Signup and view all the answers

Which type of antigen is non-immunogenic, but may act as haptens?

<p>Lipids (A)</p> Signup and view all the answers

What are sites on or within an antigen with which antibodies react called?

<p>Antigenic determinants (D)</p> Signup and view all the answers

What is the molecular weight range of high molecular weight antigens?

<p>More than 10,000 (D)</p> Signup and view all the answers

Which type of molecules are unable to induce an immune response by themselves and require a carrier molecule to act as a complete antigen?

<p>Incomplete antigens (A)</p> Signup and view all the answers

What is another name for antigenic determinants?

<p>Epitopes (A)</p> Signup and view all the answers

Which property makes molecules more effective antigens?

<p>Larger molecular masses between 5000 and 100,000 daltons (D)</p> Signup and view all the answers

What type of routes of administration are more immunogenic compared to the oral route?

<p>Parenteral routes (D)</p> Signup and view all the answers

What is the main characteristic of epitopes?

<p>Immunologically active regions that bind to specific receptors (D)</p> Signup and view all the answers

Which type of cells trap viral antigens in the body?

<p>Macrophages (A)</p> Signup and view all the answers

How are exogenous antigens mainly taken up by APCs?

<p>Phagocytosis (C)</p> Signup and view all the answers

Which of the following is NOT a human tissue antigen?

<p>Rh factor (B)</p> Signup and view all the answers

What is the major histocompatibility complex (MHC) involved in?

<p>Antigen presentation (B)</p> Signup and view all the answers

Which type of infection can lead to the generation of endogenous antigens within cells?

<p>Viral infection (A)</p> Signup and view all the answers

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