Antigen Structure, Processing and Presentation Overview
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Questions and Answers

What is an immunogen?

  • A low molecular weight substance
  • A conjugate of lipids with proteins
  • A foreign substance from the environment
  • A stimulus that produces an immune response (correct)
  • Which type of molecule can become immunogenic when coupled with a larger carrier molecule?

  • Lipids
  • Proteins
  • Polysaccharides
  • Haptens (correct)
  • What is the function of Major Histocompatibility Complex (MHC) in relation to antigens?

  • Production of antibodies
  • Formation of antigens
  • Generation of immune response
  • Antigen processing and presentation (correct)
  • Which of the following is NOT a type of antigen according to the text?

    <p>Globulins</p> Signup and view all the answers

    What differentiates an antigen from an immunogen?

    <p>Ability to generate an immune response</p> Signup and view all the answers

    Which type of molecule can be both an antigen and an immunogen at the same time?

    <p>Proteins</p> Signup and view all the answers

    What is the term used to describe the small area on the antigen molecule that reacts specifically with antibodies?

    <p>Epitope area</p> Signup and view all the answers

    Which type of antigenic determinant is recognized mainly by T cells?

    <p>Sequential determinants</p> Signup and view all the answers

    Which of the following is considered a good immunogen among proteins?

    <p>Pure proteins or glycoproteins</p> Signup and view all the answers

    What type of antigens have entered the body from the outside by inhalation, ingestion, or injection?

    <p>Exogenous antigens</p> Signup and view all the answers

    Which type of antigen is non-immunogenic, but may act as haptens?

    <p>Lipids</p> Signup and view all the answers

    What are sites on or within an antigen with which antibodies react called?

    <p>Antigenic determinants</p> Signup and view all the answers

    What is the molecular weight range of high molecular weight antigens?

    <p>More than 10,000</p> Signup and view all the answers

    Which type of molecules are unable to induce an immune response by themselves and require a carrier molecule to act as a complete antigen?

    <p>Incomplete antigens</p> Signup and view all the answers

    What is another name for antigenic determinants?

    <p>Epitopes</p> Signup and view all the answers

    Which property makes molecules more effective antigens?

    <p>Larger molecular masses between 5000 and 100,000 daltons</p> Signup and view all the answers

    What type of routes of administration are more immunogenic compared to the oral route?

    <p>Parenteral routes</p> Signup and view all the answers

    What is the main characteristic of epitopes?

    <p>Immunologically active regions that bind to specific receptors</p> Signup and view all the answers

    Which type of cells trap viral antigens in the body?

    <p>Macrophages</p> Signup and view all the answers

    How are exogenous antigens mainly taken up by APCs?

    <p>Phagocytosis</p> Signup and view all the answers

    Which of the following is NOT a human tissue antigen?

    <p>Rh factor</p> Signup and view all the answers

    What is the major histocompatibility complex (MHC) involved in?

    <p>Antigen presentation</p> Signup and view all the answers

    Which type of infection can lead to the generation of endogenous antigens within cells?

    <p>Viral infection</p> Signup and view all the answers

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