Podcast Beta
Questions and Answers
What does CFU stand for in microbiology?
What is the significance of Minimum Inhibitory Concentration (MIC) in antimicrobial testing?
What does the term 'Minimum Bactericidal Concentration (MBC)' refer to?
What is the range for the frequency of resistant mutants among viable bacterial cells?
Signup and view all the answers
What is the primary purpose of breakpoints in antimicrobial susceptibility testing?
Signup and view all the answers
Why is susceptibility not a guarantee of therapeutic success with antibiotics?
Signup and view all the answers
What does an MIC of 2 μg/ml really signify?
Signup and view all the answers
What is the significance of Susceptible Dose Dependent (SDD) for certain drugs?
Signup and view all the answers
Which committee is responsible for determining breakpoints for antibiotics?
Signup and view all the answers
What is the major disadvantage of Microbroth Dilution Method compared to Macrobroth Dilution Method?
Signup and view all the answers
What is the purpose of the Inoculum Effect in relation to a MIC test?
Signup and view all the answers
Which testing method is described as 'like taking a poll' in terms of sample size accuracy?
Signup and view all the answers
Why is it crucial to detect resistance in pathogens?
Signup and view all the answers
What is a significant consequence of undetected resistance?
Signup and view all the answers
Which type of infection involves "~25% of all infections in ICU"?
Signup and view all the answers
What percentage of hospital acquired pneumonia cases involve gram-negative bacteria?
Signup and view all the answers
Why is Hospital Acquired Pneumonia (HAP) particularly challenging to diagnose?
Signup and view all the answers
What microbial etiology complicates the diagnosis of Hospital Acquired Pneumonia (HAP)?
Signup and view all the answers
What type of testing is necessary to identify resistance mechanisms?
Signup and view all the answers
What is a key feature of molecular diagnostic testing?
Signup and view all the answers
What are some common types of infections that may require rapid pathogen identification?
Signup and view all the answers
What is a potential consequence of inadequate therapy for S.pneumoniae infections?
Signup and view all the answers
What is a disadvantage of the agar dilution method mentioned in the text?
Signup and view all the answers
Which method involves applying a plastic strip coated with an antibiotic gradient?
Signup and view all the answers
What is a common drawback of qualitative disk diffusion assays?
Signup and view all the answers
What is the aim of automated susceptibility tests mentioned in the text?
Signup and view all the answers
What can be a limitation of molecular detection of resistance genes according to the text?
Signup and view all the answers
In the context provided, what can rapid susceptibility methods help determine for serious infections?
Signup and view all the answers
What was a significant finding in the Doern study comparing different antibacterial testing methods?
Signup and view all the answers
What societal impact did rapid susceptibility methods have as mentioned in the text?
Signup and view all the answers
In the context provided, what is a concern associated with the routine use of molecular detection of resistance genes in hospitals?
Signup and view all the answers
What is highlighted as a significant advantage of rapid susceptibility methods based on environmental impact?
Signup and view all the answers