Vaccines Part 2 Transcript PDF

Off with the different types of T cells and don't panic about this picture, but it is showing you just a visualization of the definitions Like we talked about the central memory T cells circulate between the blood secondary lymphoid tissues and lymphs And so that's why those arrows are drawn here Th...

Off with the different types of T cells and don't panic about this picture, but it is showing you just a visualization of the definitions Like we talked about the central memory T cells circulate between the blood secondary lymphoid tissues and lymphs And so that's why those arrows are drawn here Those affect your memory go wherever there's inflammation. So that's why there's this big gigantic arrow circle going throughout blood You know your cells lymph secondary lymphoid tissue with more lymph because again, they're gonna go anywhere. There's inflammation and then your resident memory is shown within Your skin cells are epithelial cells here because again, they'll go Wherever the site of infection is and that's where they will live out the rest of their life They do not travel they stay where that site of infection was and so resident memory T cells are the most numerous type of memory T cell within the body Now this is showing the difference between primary and secondary immune responses here. And so you know it's talking about Differences between innate and adaptive with the assumption that we have seen the pathogen before Because again, we talked about how IgM is the first antibody produced and it has low to medium affinity because the more times We see it, you know, we have that isotope switching somatic hypermutation things like that here, too And so there is kind of that delay in the beginning because you need to present antigen to then from dendritic cells to T cells And that innate immunity is working alone alone until the adaptive response is activated and ongoing And then once we have that secondary response, we've seen it before whether it's due to a vaccine or a booster shot Or it's your second time getting a common cold You will have close cooperation between innate and adaptive immunity from the start And you will have a large number of pathogen specific cells And so vaccines use premises from both these primary and secondary responses to keep us safe There's a quick video on how vaccines work overall