Module 11: Immunity, Inflammation, Pain PDF

Summary

This document is an overview of immunity, inflammation, and pain, likely intended as study material for undergraduate students in the healthcare field. It covers topics like innate immunity, adaptive immunity, and various types of pain. The document also features chapters on specific topics like antiviral therapy, vaccines, infectious diseases, and skin infections, providing detailed insights into these key areas.

Full Transcript

**Module 11: Immunity, Inflammation, Pain** =========================================== Chapter 6: Innate Immunity - Inflammation and Wound Healing ----------------------------------------------------------- ### Learning Objectives - - - Page 492 - figure 22.9 ### Immunity - - - -...

**Module 11: Immunity, Inflammation, Pain** =========================================== Chapter 6: Innate Immunity - Inflammation and Wound Healing ----------------------------------------------------------- ### Learning Objectives - - - Page 492 - figure 22.9 ### Immunity - - - - - - - - - ### 2nd Line of Defense: Inflammation - - - - - - ![](media/image12.png) ### Local Inflammatory Response Example - - - - - - - - - - - - - - - ### 2nd Line of Defense: Acute Inflammatory Response - - ### Mast Cells - - - ### Plasma Protein System and Inflammation - - - - - - - ![](media/image38.png) ### Phagocytosis: Neutrophils and Macrophages Cellular Mediators - - - - - - Regulating Inflammation - - - - - Acute and Chronic Inflammation - - - - - - - - - - - - Chapter 7: Adaptive Immunity ---------------------------- ### Learning Objectives - - - ### Adaptive Immunity - - - - - - - ### Elements of Adaptive Immunity - - - - - - Antigens and Immunogens (the invaders) - - - - - - - - - ### Overview of Immune Response ![](media/image35.png) ### Clonal Diversity - - - - ### Clonal Selection - - - - - ### Immune Response - - - - - - ### Effector T Cells - - - - - - ### B-Cell Clonal Selection - - - ### Antibodies - - - - - - - - ### Direct and Indirect Functions of Antibodies ### Memory Cells - - - - ### Other Cells - - - - - ### Primary and Secondary Response - - - - - - - - - - - - ### Chapter 15: Pain ---------------- ### Learning Objectives - - - ### Pain - - - - Acute Pain - - - - - - - - - - - - - - - - - ![](media/image26.png) Chronic Pain - - - - - - Neuropathic Pain - - - - - - - - - - - - - - - Chapter 24: Anti-Inflammatories ------------------------------- ### Learning Objectives - - - - - ### Inflammatory Disease Examples - - - - - - - - ![](media/image34.png) - - - - - - ![](media/image13.png) ### Salicylates - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - ### Clinical Judgment (Salicylates) - - - - - - - - - - - - - - - - - - ### Propionic Acid Derivatives: Ibuprofen - - - - - - - - - - - - - - - - - ### Clinical Judgment: Ibuprofen - - - - - - - - - - - - - - - - - - - - - - ### Nonsteroidal anti-inflammatory: Celecoxib - - - - - - - - - - - - - - - - ### Immunomodulator: Infliximab - - - - - - - - - - - - - - - ### Gout - - - - - - ### Antigout: Febuxostat, Allopurinol - - - - - - - - - - - - - - Chapter 35: Analgesics ---------------------- ### Learning Objectives - - ### Pain Terminology - - - - - - ### Nonopioid Analgesics - - - - - - - ### Acetaminophen - Nonopioid Analgesic - - - - - - - - - - - - - - - - - ### Clinical Judgment: Acetaminophen - - - - - - - - - - - - - - - - - ### Morphine - Opioid Analgesic - - - - - - - - - - - - - - - ### Clinical Judgment: Morphine - - - - - - - - - - - - - - - - - - - - - ### Nalbuphine - Opioid agonist-antagonist - - - - - - - - - - - - - - - - - - - ### Migraine Headaches - - - - - - - - - - - - ### Cluster Headaches - - - - - - - - - - ### Sumatriptan - Antimigraine - - - - - - - - - - - - - - - - - **Module 11: HIV, AIDS, Transplants, Vaccines** =============================================== Chapter 8: Alterations in Immunity ---------------------------------- ### Learning Objectives - - - - ### Organ Transplant - - - - - - - - - ### Transplant Rejection - - - - - - - - - - - ### Immune Deficiencies - - - - - - - - - ### Secondary Immune Deficiencies - - - - - - - - - ### Acquired Immunodeficiency Syndrome (AIDS) - - - - ### Human Immunodeficiency Virus (HIV) - - - - - - - - - - - - - - ![](media/image28.png) - - - - - - - - - - - - - - - - - - - - - - - - - - - ### Pediatric AIDS - - - - - Chapter 32: HIV/AIDS -------------------- ### Learning Objectives - - - - - - - ### Risk Factors for HIV Transmission - - - - - - ### Therapy for Viral Infections - - - - - - ### Challenges of Antiviral Therapy - - - ### Classifications of Antiviral Therapy - - - - - - - - - - - - - - - - - ### HIV Pharmacotherapy - - - - - - - ### Pregnant Clients - - - - - - - ### Therapeutic Goals in HIV-AIDS Care - - - - - - - - - - ### Pharmacotherapy for HIV: Antiretroviral Therapy - - - - - - ### Treatment Goals of Antiretroviral Therapy - - - ### Antiretroviral Drugs - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - ### Clinical Judgment - - - - - - - - ### Occupational Therapy Exposure to HIV and Postexposure Prophylaxis (PEP) - - - - - - Chapter 33: Transplant/Immune ----------------------------- ### Learning Objectives - - - - - ### Organ Transplants - ![](media/image17.png) ### Induction Therapy - - - - ### Maintenance Therapy - - - - - - - - - - - - - - - - - - - - - - - ### Clinical Judgment: Organ Transplants - Immunosuppression - - - - - - - - - - - - - - - - - ### Calculating Absolute Neutrophil Count (ANC) - - - - - - - - - - - - - ### Role of the Nurse - - - - - - - - Chapter 34: Vaccines -------------------- ### Learning Objectives - - - - - - - ### Vaccines - - - - ### Contraindications to Vaccinations - - - - - - - ### Diseases Prevented Through Vaccination - - - - - - - - - - - - - - ### Types of Vaccinations - - - - - ### Vaccines - - ### Routes for Vaccine Administration - - - - ### Varicella Vaccine - - - - - - - - - - - - - - - ### Clinical Judgment: Vaccines - - - - - - - - - - - - - - - ### Recommended Vaccination Schedule ![](media/image36.png) - - - - - - - - - - - - - - - - - **Module 13: Infections** ========================= Chapter 9: Infection -------------------- ### Learning Objectives - - - - - - ### Nature of Infection - - - - - - - - - ### Scientific Knowledge Base - - - - - - - - - - - - ### Process of Infection - - - - - - - - - - - - - - - - - - - - ### Bacterial Infections - - - - - - - ### Tuberculosis - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - ![](media/image32.png) ### Viral Infections - - - - - - - - ### Viral Infection: Influenza - - - - - - - - - - ### Non-HIV Antivirals - - - - - - - - - - - ### Fungal Infections - - - - - - - - - - - ### Parasitic Infections - - - - - - - - - - - - ### Antimicrobial Resistance - - - - Antibiotic Resistance - - - - - - - - - - - - - - Chapter 43: Skin Infections --------------------------- ### Learning Objectives - - ### Herpes Simplex Virus (HSV) - - - - - - - - - - - - - - - - - - - - - ### Herpes Zoster (Shingles) and Varicella (Chickenpox) - - - - - - - - - - - ### Fungal Infection: Candidiasis - - - - - - - - - - - - ### Tinea Fungal Infection - - - - Chapter 44: Skin Infections - Children -------------------------------------- ### Learning Objectives - - ### Tinea Capitis - - - - - - - ### Tinea Corporis - - - - - ### Oral "Thrush" in Children - - - - - - - - - - Antimicrobial Drugs ------------------- ### How Drugs Kill Bacteria - - - - - - ### Antibacterials: Antibiotic Combination Effects - - - - - - ### Antibacterial Spectrum - - - - - - - ### Antibacterials: General Adverse Reactions - - - - - - - - - - - - - ### Know for Most Antibiotic Medications - - - - - - - - - - - - ### Superinfection - - ### Mechanisms of Hypersensitivity Reactions ![](media/image44.png) ### Anaphylaxis - - - ### Prototype Drugs ![](media/image22.png) Chapter 27: Macrolides, Oxanolidinones, Lincosamides, Glycopeptides, & Lipopeptides ----------------------------------------------------------------------------------- ### Learning Objectives - ### Macrolides - - - ### Glycopeptides - - - - - - - - - ### Lincosamides - - ### Oxazolidinones - - ### Macrolide: Azithromycin - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Clinical Judgment: Macrolides - - - - - - - - - - - - - - - - - - - Chapter 28: Tetracyclines, Aminoglycosides, and Fluoroquinolones ---------------------------------------------------------------- Learning Objectives - Tetracyclines: Doxycycline - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Clinical Judgment: Tetracyclines - Doxycycline - - - - - - - - - - - - - - - - - - Aminoglycosides: Gentamicin Sulfate - - - - - - - - - - - - - - - - Clinical Judgment: Aminoglycoside Gentamicin - - - - - - - - - - - - - - - - Fluoroquinolones: Ciprofloxacin - - - - - - - - - - - - - - - - Clinical Judgment: Fluoroquinolones - Ciprofloxacin - - - - - - - - - - - - - - - - - - - Chapter 29: Sulfonamides and Nitroimidazoles -------------------------------------------- Learning Objectives - Sulfonamides: Trimethoprim-Sulfamethoxazole - - - - - - - - - - - - - - - - - - - - - - - Clinical Judgment: Trimethoprim-Sulfamethoxazole - - - - - - - - - - - - - - - - - - - - - Chapter 32: Antimalarials, Anthelmintics, Peptides/Ambicide ----------------------------------------------------------- Malaria - - - - - - - - - - - Antimalarial Drug - - - - - - - - Antimalarial: Chronique Phosphate - - - - - - - - - - - - - - - - - - - - - - - - - - - Nursing Process: Antimalarials - - - - - - - - - - - - - - - - Helminths - - - - - - - - - - - - - - - - Anthelmintic Drugs: Ivermectin - - - - - - - - - - - Nursing Process: Anthelmintics - - - - - - - - - - - - - - - - - Antibacterial Peptide Amebicide: Metronidazole - - - - - - - - - - - - - - - - Antimicrobial and Antiprotozoal: Peptide Metronidazole - - - - - - **Module 14: Obesity, Starvation, Anorexia of Aging, Nutrition, Vitamins & Minerals** ===================================================================================== Chapter 37: Structure and Function of the Digestive System ---------------------------------------------------------- ### Learning Objectives - - - ### Gastrointestinal Tract - Enteric System ![](media/image24.png) Chapter 39: Alterations of Digestive Function in Children --------------------------------------------------------- ### Learning Objectives - - ### Cleft Lip and Cleft Palate ![](media/image7.png)![](media/image7.png) ### Esophageal Atresia ![](media/image15.png) ### Infantile Hypertrophic Pyloric Stenosis - - - - - - - - ### Intestinal Malrotation - - - - - - - - - - ![](media/image41.png) ### Meconium Syndromes - - - - - - - - - - - ### Duodenal Obstruction - - - ![](media/image14.png) ### Jejunal and Ileal Obstruction - ![](media/image3.png) ### Hirschsprung Disease ![](media/image1.png) ### Anorectal Malformations ### Diarrhea in Infants and Children - - - - - - - - - - Chapter 21: Obesity, Starving, and Anorexia of Aging ---------------------------------------------------- ### Learning Objectives - - - - - - - ### Regulation of Food Intake and Energy Balance - - - - - ### Adipose Tissue - - - - - - - ![](media/image46.png) ### Classification of Adipose Tissue - - - - - - - - - - - - - - - - - - - - ### Adipose Tissue as an Endocrine Organ - - - - - ### Obesity - - - - - - - - - - - - - - - - - - - - - - - ![](media/image30.png) ### Adipokines and Obesity - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - ### Phenotypes of Obesity - - - - - - - ### Fast Food Restaurants Starvation - - - - - - - - - - - - - - - - - - - - ### Anorexia of Aging - - - - - - - - - - - - - - - Chapter 14: Nutritional Support ------------------------------- ### Learning Objectives - - - - - - ### Nutritional Support Benefits - - - - - - - - - ### Enteral (GI Tract) Feedings: Different Types of Nutritional Support - - - - - - ### Different Types of Nutritional Support - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - ![](media/image9.png) Clinical Judgment: Enteral Nutrition - - - Parenteral Nutrition - - - - - - - - - - - - - - - - - - - - ![](media/image43.png) Clinical Judgment: Total Parenteral Nutrition - - - ### Chapter 13: Vitamin and Mineral Replacement ------------------------------------------- ### Learning Objectives - - - - - - ### Vitamin Supplementation - Deficiencies That Require Supplementation Vitamins - - - - - - - - Vitamin A - - - - - - - - - - - - - - - - - - Vitamin D - - - - - - - - - - - - - - - Vitamin E - - - - - - - - - - - - - - - - - - Vitamin K - fat soluble - - - - - - - - - - - - - - - - Vitamin B Complex - water soluble - - - - - - - - - Vitamin C - - - - - - - - - - - - - - - Folic Acid (Folate) - - - - - - - - - - - - - - - Vitamin B12 - water soluble - - - - - - - - - - - - - - - - - - - - - - Clinical Judgment: Vitamins - - - - - - - - - - - - - - - Minerals Needed for Body Functions - - - - - Iron - - - - - - - - - - - - - - - - - - Copper - - - - - - - - - - - - - - - Zinc - - - - - - - - - - - - - Chromium - - - - - - - - - - - - - Selenium - - - - - - - - - - - - - Clinical Judgment: Vitamins and Iron - - - - - - - - - - -

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