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Summary

These notes cover the communication within the brain, including neurons, neurotransmitters, and the different types of nervous systems. The material also includes details about different stages of sleep, and potential psychoactive drug effects.

Full Transcript

Communication within the brain ============================== - Neuron: - Cell in nervous system that receives, integrates, and transmits information Parts of the neuron =================== - Dendrites: - Receives messages from other neurons - Soma: - Cell body...

Communication within the brain ============================== - Neuron: - Cell in nervous system that receives, integrates, and transmits information Parts of the neuron =================== - Dendrites: - Receives messages from other neurons - Soma: - Cell body - Cell nucleus - life support of neuron - Axon: - long thin fiber that transmits signals - Myelin sheath - insulating material that coats axons and speeds transmission of info - Terminal buttons: small knobs that secrete neurotransmitters to transmit the neuron's message - Synapse: - Tiny gap between neurons where info is transmitted ![](media/image2.png) How does a neuron transmit info? ================================ - Action potential (brief electrical charge) travels down axon to terminal buttons - When action potential reaches terminal buttons, they release neurotransmitters into synapse - Neurotransmitters: - chemical messengers released from terminal buttons that travel synapse to receptors on dendrites of other neurons - When enough neurotransmitters bind to receptors sites on the next neuron's dendrites, it causes the neuron to fire - This is an "all or nothing" phenomenon Neurotransmitters ================= - Several types, each with specific functions - Receptors on dendrites are specialized: only certain neurotransmitters can bind to them - Reuptake: the process of reabsorbing unused neurotransmitters - Agonists: - Chemical that mimics action of neurotransmitters causing similar effects. - Can also stop reuptake - Antagonists - Chemical that opposes the action of neurotransmitters - Blocks the receptor sites Other cells in the brain? ========================= - Glia cells: - Cells in the nervous system that support, nourish and protect neurons - Supply nourishment - Get rid of waste (dead neurons and extra sodium ions) - Provide insulation The Nervous System ================== - Electro-chemical communication systems - Two major branches: - Central Nervous System (CNS): - Brain and spinal cord - Peripheral Nervous System (PNS): - All nerves that are outside of brain and spinal cord - Somatic Nervous System: - Nerves that connect to voluntary skeletal muscles and sensory receptors - Controls all voluntary movement of the body - Afferent nerve fibers - Carry info to CNS from the body - Efferent nerve fibers - Carry info to body from CNS - Autonomic Nervous System - Made up of nerves that connect to the heart, blood vessels, organs, glands. - Sympathetic Nervous System - Mobilizes body's recourses for emergencies - Parasympathetic Nervous System - Calming system that tries to conserve body's resources when there isn't an immediate ![](media/image4.png) Stages of Sleep: REM ==================== - REM sleep characterized by: - Rapid eye movements (REM): Every 30 sec, eyes move rapidly under closed lids - Active Brain Waves, similar to Beta waves - High level of physiological arousal - Body is "paralyzed" - Paradoxical sleep: body still, peaceful while highly aroused - Frequent dreaming - Majority of dreaming occurs in REM Stages of Sleep =============== - Every night, go through stages multiple times - 1 -- 2 -- 3 -- 2 - But instead of re-entering stage one, we enter REM - Cycle repeats throughout sleep period - 1 -- 2 -- 3 -- 2 -- REM -- 2 -- 3 -- 2 REM - Each time through takes around 90 minutes - As time goes on less time in deep sleep, more time in REM as night passes Dreaming ======== - Everyone (with healthy non-medicated brains) dreams - REM: more dreams, dreams ore likely to be bizarre, emotional, vivid memorable. - NREM: fewer dreams, dreams mundane/boring - Usually includes familiar people and places - Affected by our daily experiences and culture - Majority have negative content - Might be because they are more memorable Dreams: What Do They Mean? ========================== - Freud and Psychoanalytic Theory: dreams represent unconscious desires/ conflicts. - Manifests content - Actual content of dream - Latent content - Hidden meaning of dream - No evidence to support this view subjective - Activation-Synthesis Theory - Dreams are a byproduct of neural activity - During REM sleep, random activation of brain triggers sensory system - Brain makes sense of random firing by synthesizing it with memories - Threat simulation theory - Dreams allow us to rehearse survival strategies - Social simulation theory - Dreams allow us to rehearse strategies dealing with social/behavioral situations Sleep Problems and Disorders ============================ - Sleep Paralysis: Waking up, feeling paralyzed - Usually occurs when waking or falling asleep - Cause: Brain becomes aware before deep muscle relaxation of REM stops - Hypnogogic Sleep Paralysis: - In addition to paralysis, experience hallucinations - Stress, sleep deprivation, alcohol increase likelihood Psychoactive Drugs: Hallucinogens ================================= - Distort perceptions and evoke sensory images in the absence of sensory stimulation - "Classic hallucinogens" (LSD, DMT, Psilocybin) affect serotonin system - Have dramatic effect on senses: - Sensations intensified, hallucinations, time distortion - Synesthesia: - Blending/crossing of sensory perceptions - Ex: tasting green from eating lettuce - Also effect mood/thoughts: - Often highly emotional - Can cause mystical/dream like state - Can have "bad trip" - Possible Medical Uses: - Treatment of alcohol, nicotine, and cocaine dependence (addiction) - In terminally ill: treatment of anxiety, depression, fear of death - Treatment of "treatment resistant" depression - Very low chance of dependency (addiction), no withdrawal effects, but tolerance (and cross-tolerance) develops quickly - Cross tolerance means if u take a different version of the drug, you will still have a tolerance MDMA ==== - Hard to classify, has properties of both stimulants (happy) and hallucinogens - Serotonin agonist (increases serotonin "feel good hormone"), also increases dopamine (but less than other stimulants) - Energizing, creates feelings of euphoria, aphrodisiac properties (associated with riskier sexual practices) - An "empathogen": - Enhances social intimacy, empathy, trust, feelings of safety - Possible Medical Uses: - Treatment of PTSD - Concerns/Risks: - Dehydration (or overhydration due to fears of dehydration) - Long term heavy users: - Increased risk of depression - Anxiety - Sleep disorders - Memory and cognitive deficits due to damage of serotonin systems - Effects may not be permanent - Impossible to know how strong/pure it is - Tolerance can build quickly, mild withdrawal symptoms possible, but rates of dependency are low Marijuana ========= - Most widely used illegal drug in US - Hard to classify with properties of stimulants, depressants, and hallucinogens - Works on brain's natural endocannabinoid system - Affects many areas of the brain to produce a variety of effects - Relaxation - Euphoria - Time distortion - Appetite increases - Enhancement of sensation and feelings - Memory impairment - Medical Uses: - Paim relief - Appetite stimulation - Control of nausea - Reduction of tremors and seizures - Correcting Common Misconceptions: - Marijuana DOES NOT cause "amotivational syndrome" - Marijuana is NOT a "gateway drug" (drug that is an excuse to use harder drugs) - Marijuana CAN have harmful effects: - Lung damage from smoke - High doses can cause paranoia, panic, fast heart rate nausea, vomiting - Reaction times slowed, judgement/thinking impaired so NO DRIVING! - Memory problems - People CAN become addicted (dependent) on marijuana - Heavy users may experience mild withdrawal symptoms - Psychological dependency can occur - Using it to escape from things/ it becomes the focus of your life - Estimate 5% develop dependency Sensation and Perception ======================== - Sensation: - Simulation of sense organs - Perception: - Process of organizing and interpreting sensory information - Absolute threshold: - Lowest intensity at which participant notices stimuli half the time Sensation ========= - Difference threshold (aka the just noticeable difference): - Smallest difference between two stimuli that is needed for a person to notice half of the time - Weber's Law: - differences between bigger/more intense stimuli need to be larger to be noticed - Selective attention: - Art of focusing on a specific stimulus while ignoring others - Inattentional Blindness: - Failure to notice unexpected events when working on a tasks - Sensory Adaptation: - Change in the responsiveness of the sensory system based on the average level of surrounding sensation - Bottom-up processing: - Using individual sensory pieces to build and perceive whole sensory events - Top-down processing: - Using context, expectations, etc. to perceive whole sensory event Visual System ============= - Vision is the dominant sense for most humans - The McGurk Effect - What you see changes what you hear ![](media/image6.png) - Pupil: - Black hole in your eye that light goes into. - Changes size to control the amount of light that goes in. - Iris - Colored part of eye - Helps control the size of the pupil to let more or less light into the eye - Cornea - Cover the outside of the eye - Lens - Transparent structure behind pupil that changes shape to focus light on back eye - Accommodation: - When lens adjusts to focus image - Image is inverted when it hits back of the eye brain then processes and flips it right side up - Nearsightedness (myopia) - Faraway objects are blurry - Eye is too long - Farsightedness (hyperopia) - Nearby objects are blurry - Eye is too short or lens does not thicken enough - Presbyopia - "Old vision" - Nearby objects are blurry - Lens becomes less elastic with age - Glasses changes focus of image - Retina - Inner surface of eye - Made up photoreceptors - Light sensitive neurons - Types of photoreceptors: - Cones: - Short, stubby cells located in the center of the retina - Fovea: center of retina, which contains only cones - Vision in bright light and color vision, fine detail - Rods: - Elongated cells more concentrated on sides of retina - More sensitive to light, night vision, vision in low light, peripheral vision - Not sensitive to color - Optic Nerve: - Axons of all neurons in retina gather together and leave eye through optic disc - Blind spot: - Hole in retina where light cannot be processed 6 basic taste receptors

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