Tech Sheet_LiverSauce_RB03_web.pdf

DR SHADE’S LIVER SAUCE ® THIS INFORMATION IS PROVIDED AS A MEDICAL AND SCIENTIFIC EDUCATIONAL RESOURCE FOR THE USE OF PHYSICIANS AND OTHER LICENSED HEALTH CARE PRACTITIONERS (“PRACTITIONERS”). THIS INFORMATION IS INTENDED FOR PRACTITIONERS TO USE AS A BASIS FOR DETERMINING WHETHER TO RECOMMEND THESE...

DR SHADE’S LIVER SAUCE ® THIS INFORMATION IS PROVIDED AS A MEDICAL AND SCIENTIFIC EDUCATIONAL RESOURCE FOR THE USE OF PHYSICIANS AND OTHER LICENSED HEALTH CARE PRACTITIONERS (“PRACTITIONERS”). THIS INFORMATION IS INTENDED FOR PRACTITIONERS TO USE AS A BASIS FOR DETERMINING WHETHER TO RECOMMEND THESE PRODUCTS TO THEIR PATIENTS. ALL RECOMMENDATIONS REGARDING PROTOCOLS, DOSING, PRESCRIBING AND/OR USAGE INSTRUCTIONS SHOULD BE TAILORED TO THE INDIVIDUAL NEEDS OF THE PATIENT CONSIDERING THEIR MEDICAL HISTORY AND CONCOMITANT THERAPIES. THIS INFORMATION IS NOT INTENDED FOR USE BY CONSUMERS. Liver Sauce® is a premier liver and detoxification support formula. Our nanoformulated blend features four potent bitters to aid bile fluidity and flow, along with powerful liver and detoxification support from milk thistle, R-lipoic acid (RLA), diindolylmethane (DIM), quercetin, and luteolin. EDUCATION BILE FLOW IS CRITICAL TO HEALTH The liver plays a vital role in clearing the body of harmful toxins acquired externally from the environment and generated internally through metabolism and the gut microbiota.1 It converts toxins into water-soluble compounds via several distinct phases2,3 and produces a fluid, bile, that is released into the gut and ushers toxins out of the body via the stool. Bile flow is also critical for proper digestion,4 an intact gut lining, healthy small intestine flora, and normal cholesterol and blood sugar levels.5,6,7,8 Bile salts are antimicrobial, can denature bacterial endotoxins, and modify lipids.9,10 Stagnant bile flow impedes the flow of toxins out of the liver into the gallbladder and digestive tract for excretion.11 This includes endotoxin produced by gramnegative bacteria, a highly inflammatory bacterial byproduct that downregulates critical pumps (called phase III transporters) that transport toxins out of our cells.12,13 Poor bile flow can contribute to gastrointestinal dysbiosis and small intestinal bacteria overgrowth (SIBO).14,4 An inflamed and “leaky” gut then lets bacterial and other toxins slip into the bloodstream, triggering a systemic inflammatory response.15 That inflammatory response impairs liver and gallbladder function and further inhibits bile flow, contributing to cholestasis.16 BITTER HERBS STIMULATE BILE FLOW Bitters are herbs that support digestion, regulate blood sugar and activate the immune response.22,23,24,25 The four bitters in this formula include dandelion, gentian, goldenrod and myrrh, all to enhance elimination through the liver, gallbladder, digestive tract and kidneys. Each also offers protective antioxidant benefits. Gentian (Gentiana lutea) is one of the strongest herbal bitters and a liver protective agent that can increase levels of glutathione and superoxide dismutase.26,27 Dandelion (Taraxacum officinale) activates bile production28, has hepatoprotective effects29 and can increase antioxidant activity in the liver.30 Goldenrod (Solidago) promotes urination and elimination of toxins through the kidneys.31 Flavonoids from solidago help activate GSH-S-transferase, a critical enzyme in phase II detoxification.32 Myrrh (Commiphora myrrha) is cherished for its antimicrobial effect.33,34 It is also anti-inflammatory, antioxidant, and a cholesterol lowering agent.35,36,37 SPECIALIZED PHYTONUTRIENTS PROTECT AND SUPPORT LIVER DETOX When bile flow is enhanced and liver detoxification is stimulated, support for all three phases of detoxification is important. Milk thistle (Silybum marianum) is a premier liver-support herb that is anti-cholestatic38, antioxidant, anti-inflammatory, and hepatoprotective.39,40 Its most active constituent is silymarin, along with the flavonolignan silybin, also known as silibinin. It can prevent estrogen-induced decrease in bile-salt dependent bile flow.41 Silibinin and silymarin, R-lipoic acid, quercetin, and DIM (3,3’-Diindolylmethane) induce the critical Nrf2 pathway.42,43,44 Nrf2 is our internal, master antioxidant switch, which turns on the production of glutathione and numerous detoxifying enzymes. DIM, in combination with quercetin and luteolin, balance inflammation.45,46 Quercetin supports intestinal barrier function, reducing permeability.11 Quicksilver Delivery Systems® improves upon liposomal and emulsification technology with smaller, more stable particles made from the highest-grade ingredients available. In addition to exceptional absorption rates, these tiny liposomal and nanoemulsified particles increase diffusion across mucous membranes, enhance lymphatic circulation of nutrients, and support cellular delivery. References available at quicksilverscientific.com/liversaucereferences TS210024 Rev. 02 WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS. DO NOT USE IF PREGNANT, BREAST-FEEDING, OR PLANNING TO BECOME PREGNANT. KEEP OUT OF REACH OF CHILDREN. Consult a healthcare professional before use if you have any medical condition or are taking any other supplements or medications. Do not exceed recommended dosage. See www.quicksilverscientific.com for additional safety information. ® This information is for the use of licensed healthcare practitioners only and is intended to use as a basis for determining whether or not to recommend these products to their patients. This medical and scientific information is not for use by consumers.