Self Test 01 Haematology And Blood Transfusion PDF

MODULE CODE: MLT06210 MODULE NAME: DIAGNOSTIC HAEMATOLOGY AND BLOOD TRANSFUSION SELF TEST 01 1. Answer item one (i) to twenty (xx) by choosing the letter of the most correct answer and write it in the box provided using CAPITAL letter...

MODULE CODE: MLT06210 MODULE NAME: DIAGNOSTIC HAEMATOLOGY AND BLOOD TRANSFUSION SELF TEST 01 1. Answer item one (i) to twenty (xx) by choosing the letter of the most correct answer and write it in the box provided using CAPITAL letter. i. Which of the following viral diseases cause high titers of cold antibodies? A. Mumps. B. Measles. C. Hepatitis D. Infectious mononucleosis E. Acquired Immunodeficiency Virus ii. Which of the following is assessed by the Bleeding time test? A. Coagulation and platelet function. B. Coagulation, endothelial and platelet function. C. Coagulation function and clotting factors pathway function. D. Platelet number, platelet function and endothelial function. E. Coagulation function, endothelial function and platelet number iii. Which among the following is a disorder associated with platelets not able to adhere to the subendothelial collagen when a blood vessel is injured? A. Leukemia Disease B. Thrombocytosis Disease C. Von Willebrand Disease D. Thrombocytopenia Disease E. Venous thromboembolism Disease iv. Which of the following is a Condition characterized by haemolysis of red blood cells following exposure of oxidative stress? A. Glucose-6-phosphate dehydrogenase deficiency B. Glucose-6-pyrophosphate deficiency. C. Dehydrofolate reductase deficiency. D. Lactate dehydrogenase deficiency. E. Vitamin B12 deficiency  v. Which of the following can result due to the use of infected serum in ABO grouping? A. Occasionally a false negative reaction. B. Always it gives a false negative reaction. C. Always it gives a false positive reaction. D. Most cases it gives a false positive reaction. E. Most cases it gives false negative reaction. vi. Which of the following Coagulation factors are involved in the Intrinsic Pathway? A. XII, XI, IX, X and VIII B. XII, XI, VII, X and VIII C. XII, IX, VIII, V and X D. XII, XI, IX, VII and X E. XII, XI, IX , III and X vii. Which of the following components are involved in the Fibrinolytic system? A. Plasminogen and Adenosine Diphosphate B. Plasmin, plasminogen Activator and platelets C. Plasmin, Adenosine Diphosphate and plasminogen D. Platelets, plasminogen activator, platelet inhibitor and adenosine Diphosphate E. Plasminogen, plasminogen activator, plasmin and plasminogen activator inhibitors viii. Which of the following are mediators of vasoconstriction in primary haemostasis? A. Platelets aggregation and serotonin. B. Compounds such as ADP and serotonin. C. Compound such as ADP and thromboxanes. D. Compounds like thrombokinase and serotonin. E. Compounds such as thromboxanes and serotonin. ix. Which of the following are the major components of haemostasis? A. Platelets, coagulation, fibrinolytic and aggregation. B. Platelets, vascular system, fibrinolytic and serotonin. C. Platelets, serotonin, fibrinolytic and endothelial system. D. Vascular system, platelets, coagulation and fibrinolytic. E. Vascular system, platelets, coagulation and white blood cells. x. Which of the following leads to the occurrence of Haemolytic Disease of a New born due to ABO incompatibility? A. Mother is blood group B and newborn is group A B. Mother is blood group A and newborn is group O C. Mother is blood group O and newborn group A or B D. Mother is blood group O Rhesus positive and new born group A or B Rh positive E. Mother is blood group O negative and newborn group A or group B Rh positive  xi. Which of the following is a compatibility test used to detect in vivo sensitization of Red blood cells? A. Fragility test B. Haemolysin test C. Capillary resistance test D. Direct Antiglobulin test E. Indirect antiglobulin test xii. Which of the following variations in amino acid arrangement leads to genetic changes that cause sickle cell disease? A. Valine replaces glycine in the sixth position of β- globin chain of haemoglobin. B. Valine replaces glutamic acid in sixth position of β- globin chain of haemoglobin C. Glycine replaces valine in the sixth position of β- globin chain of haemoglobin. D. Valine replaces glutamic acid in sixth position of α- globin chain of haemoglobin. E. Glutamic acid replaces methionine in sixth position of α - globin chain of haemoglobin. xiii. Which of the following antibodies are found in serum from Bombay phenotype individual? A. Antibody B and antibody O. B. Antibody A and antibody B. C. Incomplete anti D antibodies. D. Antibody A, antibody B and antibody H. E. Incomplete antibody D and antibody H. xiv. Which of the following technique is used in the laboratory for conclusive diagnosis of Leukemia? A. Venous blood B. Computed tomography C. Peripheral blood smears D. Bone marrow aspirations E. Gene expression profiling xv. Which of the following is a haematological disorder characterized by bite and blister cells in the peripheral thin blood smear? A. G6PD Deficiency B. Aplastic anaemia C. Pernicious anaemia D. Chronic blood loss E. Iron deficiency anaemia  xvi. Which of the following parameters is RAISED in an individual with Iron Deficiency Anaemia? A. MCV B. MCH C. Serum Iron D. Serum ferritin E. Total Iron Binding Capacity xvii. Which of the following is the major component of the acquired Immune system? A. Skin B. Lysozyme C. Macrophages D. Lymphocytes E. Normal flora bacteria xviii. Which of the following can cause FALSE NEGATIVE result in ABO Blood Grouping? A. Infected serum B. Cold Agglutinin C. Infected red cells D. Rouleaux formation E. Hemolysis of red cells xix. Which of the following is the immunoglobulin class of the naturally occurring ABO antibodies? A. IgG B. IgM C. IgA D. IgD E. IgE xx. Which of the following is the suitable stain for manual Reticulocyte Count Test? A. Brilliant cresyl blue stain B. Bromothymol blue stain C. Methylene blue stain D. Leishman stain E. Giemsa stain