PPT 20 Module 3 ClinPharm PDF

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 + 1 !! year Elimination) Mitigation of symptoms. Modification of the EX : HIVPX. PX) disease > process. - Rational Selection > - 5 Rs (Dose Drug , , Route Time , , Erythematosus) symptoms Hydralazina like of drug-related problems > Resolution (Systemic Lupus - > - SIE - ·. Monitoring Prevention of - > 3 Dosing > - The dose makes the poison (Paracelsus) drug misadventure > - ADEs Butterfly-Rash Control of the px's overall therapy program. phenytoina > - SR's > - Rather than Drug-oriented XMOTOR Max Dose = 4g/4000mg Px MD5 &RPh - , > - Interprofessional Collaboration I PT & OT ( D > - Hepatotoxicity/Hepatonecrosis # NAPQ1 > - (YP450 = N-actyTimin Antidote : NAC ↓ crtations Non-toxic By products : 1 Cysteine. 2 Mercaptonic Acid  develops uker > - Over 60 old. Physical Dependence years taking dirnetics. Psychological Dependence Have YBP and & discuss. WI pre-existing Kidney discuss. Children/Teenagers recovering from viral infection. Decongestants Laxatives Antihistamines Sleep Aids Antacids Drycough/Prevent Ephedrine cough > - drycough phlegm - = Note : OTDrug St EE Mocolytiaroductive cough & Increase Dose : Brain Damage , Seizure , death. Children : Consult MD. ACE Hospital Pharmacy Community Pharmacy Nursing Homes ↑ BP + ↓BP = 150/120 = 10/110 > - Breast Cancer = Anastrozole , Tamoxifen > - Pharmacoeconomics 1 ADR Home Carc Services Clinics NSAIDS =CISEbleeding Ste : 30 mins) = Pxhasulcer = PPIs. 3 Oristat = + Vit. ADEK = Fat-soluble. = Hypovitaminosis. = weight loss , anti-obesity. ↳ PX interaction/TX Plan = Solution:Giv VitaminsContainingA. 3 FQ & TC = + Multivalent cations. I = Antibiotion (form chelates) = ↑ Metabolite = Note : Do not take antibiotics wh multivalent cation compounds. (P(P) ↳ Cantacids , milk ( + Other HCP XX  Cherbal products supplements vitamins) , , > - Most Important ! > - Note : Objective info from the - MD. y cigarettes y = X10 years = 1 3. smoking pack/year ! > - Info from the pX ! - > Constant !  Abdominal Part = 1-A-Perdiscontoa 7 General Flow & 9) Instrument &< > - Longs Crackle Stethoscope > - Medtech D monitoring > nurses > - - ~ No Ex (Prescription) ~ Prescribed by Official Prescriber ~ Off-the-shelf in stores ~ Bought & Pharmacy ~ Regulated by FDA 1 only ~ Intended to be used by person / OTC Drug Monographs FDA ~ Regulated by  Prescriber's Info # # PX's info Date (valid for 1 month) Superscription 60 X Inscription (info about the drug) Subscription Cinstruction to the Y ISmL RPh) Transcription Prescriber's signature (Instruction to PX) ↓ License No. valid for 3yrs. Small number of population. ADR] PhaMrchlagthan pas a * & Post-marketing Surveillance oxious ↓ Phase IV ↓ ADR happens at normal close. Just understand ! Collaboration Morning Sickness -) for morning sickness Interprofessional y ↑ Thal↓ idomidPhocomagic > - a ↳ gray baby syndrome ↓ Chloramphenicol Jetracycline, , Balproic Acid , Metimazole drugsthatcan Pass through plan > - state  Narrow = Prone Toxicity Wide = Safe T = ESO T 5 4 10 > - Safer D # # * ↓ # # * D ·no 1. Inaccurate/incomplete guidelines will provide the wrong info for ACP. "To do harm" and X do Harm than. good > - no no #. 2 Developing and updating guidelines. >Difficulttimeconsuming & mustbe * - done on a regularschea security. 3 Guidelines provide false sense of. 3. Allows for improved availability of medicines. # (STGs) · ] Follow ! * ↑ Stage/category =  * Cockcroft-Gault Equation = CrC) * dialysis CrCl = Co-agXWt(49))Mal CrCl = CoWt(9x085]Fa are · DrughSO DugBESO s Ex : Costs for drugs , investigations physician visits, , hospitalization , laboratory tests. · Drugh#995 DugBE] 8 Benefits Ex : transportation , food , lodging. · Ex : Loss in productivity , increased workloads. Drug A#2000 DugBESO E ↓ DRUG A VS. DRUG B Choose ↑ : Quality Value Effectivity S 4 years years 0 8 Utility. 0. 7 2 4. 2 8.  1. 1. 3. i ato mi ↓ lengthy follow-up ! RCT ↓lasibo 3. = No Pharmaceutical Standard Treatment = Studied Effect ! 1 Qualitative statistically proved , individuals , non-blind , = safety = 80-100 healthy MTC is determined. = effectiveness = 100-300 pX wh target discuse , single blinded , MEL. &. standard X - S &E 300-1 , 000 px w double blinded = = , animal = AE/ADE) SE test tobe glassware ,  I published · I > - pubMED ↳ Primary & Secondary (summarized) = Direct interaction to px , educate ! health Improve public. = = Patient Medication File/Profile = Medication Reconciliation Process ~is ra pers = 60 packs/year > = arrow (-) = Abdominal  = Normal Description "Polyria = ↑ urination. 2 Polydipsia = ↑ H20l Water intake Polyphagia ↑ Appetite > red-orange Rifampicin = > - = formintheKidney,solidmus ,trictioan ~ - Hydrated dehydrated/taking sp. medication  Acidic Basic Acidic LUNA HIPE Basic HIPE LUNA > - mean stream = Ind patak * D *  inelets > - > - 1. Proteins 3. Scrum Femalea # # Polycythemia - dehydration Anemia > - What type of anemia ? dengue polycythemia , vera , dehydrated blood loss , hemolytic anemia ,overhydration · L increase or Overhydration SlADH-Syndrome of Inappropriate Antidiuretic Hormone Sucretion > - clotting , immune response. ↑ Agb = Darker Normal RBC color ↓ Agb color Blood loss , hemolytic anemia. espouse to viers , infected tuba WataMakin cl , to a => > - ↓ Cl-mediatedImmunity calls , targeted by HIV/AIDS , activated Balls &T cells. inflammation tissue necrosis M1 , malignancies , 2) destroy infected CD8 cells. Cytotoxic , T cells , , = rheumatoid collagen discuss.  Pret Extwinsas Warfarin - > Blood dot - Coagulationa Blood thinner y * Prothrombin Bleeding (slow Coagulation (fast blood blood dot) dot) = Standard Value Wplasma + 16 Fibrinogena HaPiIt s intrinsic pathway 4. Von Willebrand Factor Acparin + Basophils  If Ha Renal Impairement Renal Disease > - Due to reduce exaction. ↓ Muscle Mass- > Music Wasting Waste < Blood concentrated to NAS & BUW GIT. Protein Malnutrition ↑ Nitrogen ↑ Protein Intake > - in Upper GI Bleeding DEA > - Impaired Kidney , biomarker for Heart Attack ! Hepatic Impairement- > Live is responsible for Urea Synthesis. Protein Malurtrition > - Reduced urea production , limited protein breakdown. > - Muscle Breakdown - > AMG 10 A > - Liver ~ Cardiac Muscle = For cell movement Hepatocellular Damage 1 Saraghae = > - Acpatobiliary Tract Obstruction > - Hepato Cellular Injury. Bilirubin Levels Bilirubinuria > - High in the blood. MI. Cellular Injury in Liver Damage. Rhabdomyolysis.  Urine * X VA crystal in joints > - Kidneya Early Pancreatic Inflammation Lipid V Elevated before 3rd & 4th > - Brain Damage > - Cardiovascular Diseases CA = Cancer % Major > - Primary Intra Extra Di So Phi Chlo Minor > - Secondary Intra Extra Mi Co Juli Bio  - * * * R Calcium Vit FeC(aDSeE ↓ Stum = Rate of enzymatic reaction. = Normal Caloric Intake , Protein deficiency. Basal Metabolic Rate. blurred distorted vision. of the eye that or = = Common Refractive error causes solution. = pH of a & Skeletal Muscle # # O2 is not available in y - > Folate/Folic Acid sufficient amounts. = Normal ↓ Glucose-6 - P04 Color Pala > - Dehydrogenase OSTEOCLAST vs. OSTEOBLAST ↓ ↓ Bone Breaking Bone Building  > - Metabolic Equal ↓W Respiratory Opposite Arterials I CO2 HCOs = = Respiratory Acidosis/Alkalosis Metabolic Acidosis/Alkalosis pH = ↓ Acidosis , ↑ Alkalosis  > - Vit B7. ↳ Pantothenic Acid Respiratory ↑i Mosis - Metabolic - Normal