Summary

This document is a lecture (9) on physiology, focusing on the higher control of autonomic functions. It details the integration of autonomic functions, including reflex mechanisms in the spinal cord, the brain stem's role in vital functions, and the higher control centers (hypothalamus and cerebral cortex).

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Physiology Higher control of autonomic functions LECTURE (9) DR. El-Sawy 0 Physiology Higher control of auton...

Physiology Higher control of autonomic functions LECTURE (9) DR. El-Sawy 0 Physiology Higher control of autonomic functions Autonomic functions are integrated within CNS This occurs at different levels. Simple autonomic functions are integrated reflexly e.g.  Primary centers for these reflexes are found in sacral Micturition, defecation & erection segments of spinal cord.  Spinal vasomotor centers (LHCs) : Vascular tone a) Maintain vascular tone b) Integrate some cutaneous vascular reactions. DR. El-Sawy 1 Physiology Higher control of autonomic functions  Vital centers that control: a) Cardiovascular & respiratory functions. b) Gastric secretion & vomiting. Medulla oblongata Pons  Control respiration and salivary secretion.  Control micturition and ocular reflexes i.e. pupillary light reflex and accommodation reflex. Midbrain DR. El-Sawy 2 Physiology Higher control of autonomic functions  It is principal higher center for autonomic nervous system  Considered as the head ganglion of autonomic nervous system.  Hypothalamus regulates various functions 1) Food intake 2) Adrenaline secretion 3) Body temperature Playing an important role in maintaining 4) Body water internal environment constant.  Hypothalamus can affect the activity of almost all the brain stem autonomic centers i.e. a. Stimulation of anterior nuclei of hypothalamus  ↑ parasympathetic functions :  ↓ heart rate, ↓ arterial blood pressure, pupillary constriction  ↑ motility of GIT and micturition b. Stimulation of posterior nuclei of hypothalamus  ↑ sympathetic functions :  ↑ heart rate, ↑ arterial blood pressure, pupillary dilatation  Erection of hair and adrenaline secretion DR. El-Sawy 3 Physiology Higher control of autonomic functions  Certain areas in the cerebral cortex can modify the autonomic functions either directly or through reticular formation e.g. 1- Cardiovascular and gastrointestinal changes :  That occur during psychological disturbances (e.g. acceleration of heart & increased blood pressure). 2- Increased blood flow in the skeletal muscles during exercise. 3- Increased secretion of saliva and gastric juice :  Even on thinking or seeing of food (conditioned reflex). 4- Voluntary control of micturition or defecation. 5- Some conscious control of heart rate & respiratory rate by yoga players. DR. El-Sawy 4 Physiology Higher control of autonomic functions  Group of tracts and nuclei that form a ring (limbus) around Def brain stem.  The limbic system, plus hypothalamus, are concerned with emotions (such as fear, anger, sadness, hunger and memory). Functions  Limbic stimulation produces autonomic effects, particularly changes in arterial blood pressure and respiration in response to emotional reactions. DR. El-Sawy 5

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